Bioactive Compound Series
Bioactive compounds exert a wide range of biological effects by interacting with molecular targets and modulating cellular processes. They are valuable tools for drug discovery, target validation, and mechanistic research.
MedChemExpress (MCE) offers a comprehensive portfolio of bioactive compounds for high-throughput screening (HTS), high-content screening (HCS), and drug repurposing. The collection includes over 30,000 compounds targeting more than 1,500 proteins or protein families across 20+ signaling pathways.
-
Novel Bioactive Compound Library3,288 compoundsHY-L111
-
Targeted Diversity Library2,289 compoundsHY-L099
-
Bioactive Compound Library Plus32,925 compoundsHY-L001P
-
Bioactive Compound Library27,319 compoundsHY-L001
-
Multi-Target Compound Library7,468 compoundsHY-L176
-
Bioactive Compound Library Max30,607 compoundsHY-L181
-
Withdrawn Drug Compound Library232 compoundsHY-L140
-
EMA-Approved Drug Library729 compoundsHY-L116
-
Pediatric Drug Library712 compoundsHY-L104
-
Drug Repurposing Compound Library5,154 compoundsHY-L035
-
Drug Repurposing Compound Library Plus6,161 compoundsHY-L035P
-
Clinical Compound Library2,569 compoundsHY-L026
-
Clinical Compound Library Plus3,306 compoundsHY-L026P
-
NMPA-Approved Drug Library1,532 compoundsHY-L053
-
FDA-Approved Drug Library Mini3,236 compoundsHY-L022M
-
FDA-Approved Drug Library3,236 compoundsHY-L022
-
FDA-Approved Drug Library Plus3,671 compoundsHY-L022P
-
FDA Approved & Pharmacopeial Drug Library3,748 compoundsHY-L066
-
Off-patent Drug Library2,920 compoundsHY-L141
-
FDA-Approved Anticancer Drug Library1,544 compoundsHY-L122
-
Classic FDA-Approved Drug Library168 compoundsHY-L261
-
Gut Microbial Metabolite Library473 compoundsHY-L078
-
Human Metabolite Library6,745 compoundsHY-L123
-
Human Endogenous Metabolite Compound Library759 compoundsHY-L030
-
Microbial Metabolite Library940 compoundsHY-L084
-
Mouse Metabolite Compound Library329 compoundsHY-L217
-
Amino Acid Metabolite Compound Library192 compoundsHY-L227
-
Mass Spectrometry Human Metabolite Library6,104 compoundsHY-L215
-
Nucleotide Metabolite Compound Library81 compoundsHY-L234
-
Lipid Metabolite Compound Library144 compoundsHY-L228
-
Mass Spectrometry Human Endogenous Metabolite Library663 compoundsHY-L207
-
Membrane Receptor-targeted Compound Library7,174 compoundsHY-L150
-
Membrane Protein-targeted Compound Library8,043 compoundsHY-L149
-
Coagulation and Anti-coagulation Compound Library1,533 compoundsHY-L136
-
Osteogenesis Compound Library1,006 compoundsHY-L131
-
Chemokine Compound Library264 compoundsHY-L132
-
Nuclear Receptor Compound Library1,099 compoundsHY-L126
-
5-HT Receptor Compound Library430 compoundsHY-L121
-
GABA Receptor Compound Library209 compoundsHY-L120
-
Potassium Channel Compound Library341 compoundsHY-L119
-
Sodium Channel Blocker Library199 compoundsHY-L118
-
Calcium Channel Blocker Library222 compoundsHY-L117
-
Oxygen Sensing Compound Library4,397 compoundsHY-L045
-
Wnt/Hedgehog/Notch Compound Library663 compoundsHY-L020
-
TGF-beta/Smad Compound Library467 compoundsHY-L018
-
Stem Cell Signaling Compound Library2,985 compoundsHY-L017
-
Protein Tyrosine Kinase Compound Library1,706 compoundsHY-L016
-
PI3K/Akt/mTOR Compound Library1,182 compoundsHY-L015
-
NF-κB Signaling Compound Library1,857 compoundsHY-L014
-
Transcription Factor-Targeted Library2,618 compoundsHY-L090
-
Neuronal Signaling Compound Library3,968 compoundsHY-L013
-
Membrane Transporter/Ion Channel Compound Library2,299 compoundsHY-L011
-
MAPK Compound Library1,195 compoundsHY-L010
-
Kinase Inhibitor Library4,037 compoundsHY-L009
-
Phosphatase Inhibitor Library185 compoundsHY-L081
-
JAK/STAT Compound Library745 compoundsHY-L008
-
Immunology/Inflammation Compound Library8,746 compoundsHY-L007
-
Histone Modification Research Compound Library939 compoundsHY-L024
-
Protein-protein Interaction Inhibitor Library833 compoundsHY-L109
-
GPCR/G Protein Compound Library3,532 compoundsHY-L006
-
Epigenetics Compound Library2,059 compoundsHY-L005
-
Cell Cycle/DNA Damage Compound Library3,570 compoundsHY-L004
-
Ubiquitination Compound Library508 compoundsHY-L050
-
Reprogramming Compound Library3,282 compoundsHY-L039
-
Differentiation Inducing Compound Library2,625 compoundsHY-L038
-
Antioxidant Compound Library2,549 compoundsHY-L037
-
Neurotransmitter Receptor Compound Library2,595 compoundsHY-L062
-
Cytoskeleton Compound Library2,364 compoundsHY-L060
-
Angiogenesis-Related Compound Library3,738 compoundsHY-L088
-
Mitochondria-Targeted Compound Library1,207 compoundsHY-L089
-
Endoplasmic Reticulum Stress Compound Library385 compoundsHY-L054
-
Exosomes Compound Library53 compoundsHY-L072
-
Mechanoreceptors Compound Library388 compoundsHY-L095
-
TCA Cycle Compound Library73 compoundsHY-L148
-
Cuproptosis Compound Library463 compoundsHY-L133
-
Metabolism/Protease Compound Library7,412 compoundsHY-L012
-
Glycolysis Compound Library1,418 compoundsHY-L058
-
Autophagy Compound Library2,114 compoundsHY-L029
-
Apoptosis Compound Library3,698 compoundsHY-L003
-
Ferroptosis Compound Library1,275 compoundsHY-L051
-
Glucose Metabolism Compound Library1,824 compoundsHY-L092
-
Lipid Metabolism Compound Library1,026 compoundsHY-L091
-
Glutamine Metabolism Compound Library1,881 compoundsHY-L064
-
Pyroptosis Compound Library2,091 compoundsHY-L059
-
Anti-Cancer Metabolism Compound Library3,876 compoundsHY-L083
-
Lactic Acid Metabolite Compound Library59 compoundsHY-L250
-
Mitophagy Compound Library665 compoundsHY-L180
-
Epigenetics Compound Library Mini294 compoundsHY-L005M
-
Cytokine Inhibitors Library1,444 compoundsHY-L161
-
Serine/Threonine Kinase Inhibitor Library2,321 compoundsHY-L164
-
Dopamine Receptor Compound Library276 compoundsHY-L165
-
Ion Channel Compound Library1,759 compoundsHY-L166
-
Energy Metabolites Library86 compoundsHY-L263
-
Extracellular Vesicles (EVs) Compound Library713 compoundsHY-L168
-
Cell Death Inhibitor Library Mini23 compoundsHY-L162M
-
High-Efficiency Gene Editing Compound Library769 compoundsHY-L244
-
RNA Binding Bioactive Compound Library858 compoundsHY-L248
-
Cell Proliferation Compound Library3,708 compoundsHY-L201
-
Mitochondrial Protection Compound Library1,131 compoundsHY-L144
-
Metabolic Enzyme Compound Library4,441 compoundsHY-L146
-
Lactylation Compound Library6,256 compoundsHY-L249
-
Protease Inhibitor Library964 compoundsHY-L147
-
Mitochondrial Toxicity Compound Library539 compoundsHY-L155
-
Kinase Inhibitor Library Mini270 compoundsHY-L009M
-
KRAS Targeted Compound Library82 compoundsHY-L260
-
Cyclic Peptide Library100 compoundsHY-L110
-
Peptide Library2,706 compoundsHY-L105
-
Nucleotide Compound Library594 compoundsHY-L044
-
Lipid Compound Library2,054 compoundsHY-L043
-
Glycoside Compound Library912 compoundsHY-L042
-
Heterocyclic Compound Library6,519 compoundsHY-L138
-
Macrocyclic Compound Library471 compoundsHY-L041
-
Covalent Screening Library Plus6,135 compoundsHY-L036P
-
Covalent Screening Library1,613 compoundsHY-L036
-
Peptidomimetic Library371 compoundsHY-L033
-
Cysteine Targeted Covalent Library5,322 compoundsHY-L153
-
Boronic Acid Compound Library169 compoundsHY-L167
-
Peptide Compound Library869 compoundsHY-L105S
-
Dipeptide Compound Library80 compoundsHY-L255
-
Fatty Acids Compound Library427 compoundsHY-L182
-
Ionizable Lipid Compound Library91 compoundsHY-L251
-
Cysteine Targeted Covalent Fragment Library3,787 compoundsHY-L154
-
PROTAC Library568 compoundsHY-L151
-
Molecular Glue Compound Library127 compoundsHY-L137
-
Tumorigenesis-Related Compound Library146 compoundsHY-L100
-
Drug Metabolite Library456 compoundsHY-L098
-
Animal Disease Model Inducer Library52 compoundsHY-L097
-
Inactive Ingredient Library179 compoundsHY-L096
-
Chemical Probe Library282 compoundsHY-L063
-
Orally Active Compound Library5,589 compoundsHY-L061
-
CNS-Penetrant Compound Library1,214 compoundsHY-L028
-
Toxins for Antibody-Drug Conjugate Research Library115 compoundsHY-L023
-
Food-Sourced Compound Library2,050 compoundsHY-L094
-
Food Additive Library451 compoundsHY-L093
-
Drug-Induced Liver Injury (DILI) Compound Library642 compoundsHY-L076
-
Target Protein Ligand Library130 compoundsHY-L129
-
E3 Ligase Ligand Library185 compoundsHY-L128
-
Antibiotics Library745 compoundsHY-L067
-
Neuroprotective Compound Library1,866 compoundsHY-L070
-
Non-steroidal Anti-Inflammatory Compound Library636 compoundsHY-L130
-
Macrophage Related Compound Library290 compoundsHY-L174
-
Radiosensitizer Library40 compoundsHY-L179
-
Alkyne Compound Library438 compoundsHY-L258
-
Antibody Inhibitor Library1,999 compoundsHY-L177
-
Cancer Stem Cells Compound Library3,590 compoundsHY-L135
-
Immunopotentiator Compound Library150 compoundsHY-L172
-
Flavors and Fragrances Compound Library497 compoundsHY-L242
-
Highly Selective Inhibitors Library6,343 compoundsHY-L158
-
Radioprotector Library3,134 compoundsHY-L178
-
Inflammasomes related Compound Library180 compoundsHY-L175
-
Anti-Drug-Resistant Compound Library722 compoundsHY-L169
-
Azide Compound Library98 compoundsHY-L256
-
Steroid Hormones Library70 compoundsHY-L239
-
Neurotransmitter Compound Library53 compoundsHY-L186
-
Cell Death Library3,906 compoundsHY-L162
-
Mitochondrial Toxicity Compound Library539 compoundsHY-L155
-
Pesticide Compound Library537 compoundsHY-L183
-
Allosteric Modulators (AMs) Compound Library259 compoundsHY-L170
-
Plant Hormone Library45 compoundsHY-L240
-
Chinese Baijiu Compound Library679 compoundsHY-L241
-
Environmental Pollutant Compound Library292 compoundsHY-L247