1. Recombinant Proteins
  2. Enzymes & Regulators
  3. Serine/Threonine Kinase Proteins
  4. AKT Serine/Threonine Kinase 1 (AKT1)

AKT Serine/Threonine Kinase 1 (AKT1)

Cat. No. Product Name / Synonyms Species Source
  • HY-P74421
    AKT1 Protein, Human (sf9, His)

    RAC-alpha serine/threonine-protein kinase; PKB; RAC-PK-alpha; AKT1; RAC

    Human Sf9 insect cells
    AKT1 Protein, part of the AKT kinase family, crucially regulates metabolism, proliferation, survival, growth, and angiogenesis. Phosphorylating over 100 substrates, it orchestrates insulin-induced SLC2A4/GLUT4 translocation, impacting glucose uptake, and governs glycogen storage by inhibiting GSK3A/B. AKT1 mediates insulin-stimulated protein synthesis via mTORC1, regulates FOXO factors, influences NF-kappa-B-dependent gene transcription, and enhances CREB1 activity. It modulates lipid metabolism, inhibiting lipolysis, and is involved in cell migration, adhesion, placental development, and responses to growth factors like PDGF, EGF, insulin, and IGF-I. Its role in SPATA13-mediated regulation adds complexity, highlighting AKT1's central role in cellular homeostasis and responsiveness to cues. AKT1 Protein, Human (sf9, His) is the recombinant human-derived AKT1 protein, expressed by Sf9 insect cells, with C-His labeled tag. The total length of AKT1 Protein, Human (sf9, His) is 480 a.a., with molecular weight of ~57 kDa.
Cat. No. Product Name Effect Purity