Learning Centers

Explore emerging synthetic lethal vulnerabilities beyond BRCA–PARP and advances in their discovery and prediction through CRISPR screening, organoids, multi-omics, and AI.

Review the metabolic regulation of ferroptosis through iron homeostasis, lipid peroxidation and antioxidant defence, and the emerging polyamine–iron buffering axis.

Immunocytochemistry and immunofluorescence use antibodies and fluorescent labels to visualize specific molecules on the cell surface or inside cells. A typical workflow includes sample preparation, fixation, permeabilization, blocking, antibody incubation, counterstaining, mounting, and imaging.

Explore conserved antiviral mechanisms across mammals and bacteria, from virus recognition and immune signaling to metabolic defense and gasdermin-mediated cell death, and their implications for innate immune evolution.