Explore how anti-Aβ therapy is reshaping the AD treatment landscape, the rationale for multi-pathology combination strategies, and advances in biomarker-guided precision treatment.
Learning Centers
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Beyond Aβ Clearance: Exploring Multi-Pathology Strategies in Alzheimer’s Disease -
Beyond Target Competition: Payload Chemistry and the Next Stage of ADC Design Explore the rise of TOP1i-class payloads, the impact of payload–linker design on therapeutic window and developability, and how novel payloads are expanding ADC design boundaries. -
Molecular Glues: Rewiring Protein Interactions for Targeted Degradation Review the evolution of molecular glues from serendipitous discovery to rational design, highlighting how emerging targets and advances in screening, proteomics, structural biology, and AI are expanding the druggable proteome. -
Restoring Immune Tolerance: New Insights into Autoimmune Disease Research Explore the mechanisms driving immune tolerance breakdown in autoimmune diseases and emerging tolerance-restoring strategies, with a focus on IL-2-based immune modulation.
