1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. EGF superfamily
  4. Betacellulin

Betacellulin (BTC) is a member of the epidermal growth factor (EGF) family which was originally identified as a secreted growth factor from pancreatic β-cell insulinomas. BTC is synthesized in a wide range of tissues of the adult body and in a large number cultured cells, including smooth muscle cells and epithelial cells. BTC has a high affinity and specificity for ErbB1/EGFR and ErbB4 and induces the growth of certain epithelial cell types. Homologous or heterologous dimers of ErbB family receptor are then formed to activate signal transduction pathways, such as PI3K/PDK1/Akt and RAS/RAF/MEK/Erk, leading to a series of biological effects. BTC has been implicated in a number of physiologic processes, including β-cell proliferation, keratinocyte proliferation and angiogenesis. BTC acts as an important regulator of ovarian follicle development, and can stimulate oocyte maturation and cumulus expansion.

Cat. No. Product Name / Synonyms Species Source
  • HY-P7005
    Probetacellulin Protein, Human

    rHuBetacellulin; Probetacellulin; BTC

    Human E. coli
    Probetacellulin Protein, Human is a glycoprotein, improves glucose tolerance by promoting β-cell differentiation and regeneration from ductal and/or acinar cells.
  • HY-P7142
    Probetacellulin Protein, Mouse (HEK293)

    rMuBetacellulin; BTC; Probetacellulin

    Mouse HEK293
    Probetacellulin Protein, Mouse (HEK293), a member of the epidermal growth factor (EGF) family, induces differentiation of pancreatic β-cells and promotes regeneration of β-cells in experimental diabetes.
  • HY-P70073
    Betacellulin/BTC Protein, Mouse (His)

    rMuBetacellulin/Btc, His; Btc; Betacellulin; Betacellulin; epidermal growth factor family member; Betacellulin; epidermal growth factor family member; isoform CRA_a; mCG_12529

    Mouse E. coli
  • HY-P7328
    Probetacellulin Protein, Human (HEK293)

    rHuBetacellulin; BTC

    Human HEK293
    Probetacellulin Protein, Human (HEK293) is a glycoprotein produced in HEK293 cells, improves glucose tolerance by promoting β-cell differentiation and regeneration from ductal and/or acinar cells.
  • HY-P7329
    Probetacellulin Protein, Mouse

    rMuBetacellulin; BTC

    Mouse E. coli
    Probetacellulin Protein, Mouse, induces differentiation of pancreatic β-cells and promotes regeneration of β-cells in experimental diabetes.
  • HY-P75478
    Betacellulin/BTC Protein, Mouse (HEK293, His-hFc)

    Btc; Betacellulin; Betacellulin epidermal growth factor family member

    Mouse HEK 293
  • HY-P77305
    BLOT2 Protein, Blomia tropicalis (HEK293, His)

    Type 2 allergen Blo t 2.047

    Others HEK 293
Cat. No. Product Name Effect Purity