Siglec-3/CD33
Siglec-3 (CD33) defines the CD33-related Siglec subgroup and is a canonical myeloid differentiation marker, present on myeloblasts, promonocytes and monocytes while absent from mature granulocytes and lymphoid cells. Structurally it is a compact type I transmembrane receptor with a single V-set Ig domain, one C2-set domain and cytoplasmic ITIM motifs that mediate inhibitory signaling upon binding sialylated glycans. CD33 gained prominence as the target of the antibody-drug conjugate gemtuzumab ozogamicin in acute myeloid leukemia and is now pursued with bispecific and other conjugate formats. Genome-wide studies have also identified CD33 as a susceptibility locus for Alzheimer's disease through effects on microglial amyloid-beta uptake.
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Siglec-3/CD33 Recombinant Proteins (19)
Siglec-3/CD33 Protein, Human (HEK293, hFc)
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Cat. No.: HY-P73642
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript; P67; CD33 Antigen; Sialic Acid-Binding Ig-Like Lectin 3; Siglec-3
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Siglec-3/CD33 Protein, Mouse (HEK293, Fc)
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Cat. No.: HY-P73640
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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Siglec-3/CD33 Protein, Mouse (HEK293, His)
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Cat. No.: HY-P72473
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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Siglec-3/CD33 Protein, Human (HEK293)
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Cat. No.: HY-P73643
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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Siglec-3/CD33 Protein, Cynomolgus/Rhesus Macaque (HEK293, His)
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Cat. No.: HY-P75651
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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Siglec-3/CD33 Protein, Human (HEK293, Fc-Myc)
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Cat. No.: HY-P72021
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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Siglec-3/CD33 Protein, Human (HEK293, His-Avi)
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Cat. No.: HY-P78407
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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FITC-Labeled Siglec-3/CD33 Protein, Human (HEK293, Fc)
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Cat. No.: HY-P701262
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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Siglec-3/CD33 Protein, Human (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P701037
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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Siglec-3/CD33 Protein, Human (HEK293, Fc-His)
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Cat. No.: HY-P72472
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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Siglec-3/CD33 Protein, Mouse (HEK293)
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Cat. No.: HY-P73641
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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Siglec-3/CD33 Protein, Human (HEK293, His)
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Cat. No.: HY-P73644
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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Siglec-3/CD33 Protein, Cynomolgus/Rhesus Macaque (Biotinylated, HEK293, His)
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Cat. No.: HY-P75652
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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Siglec-3/CD33 Protein, Human (Biotinylated, HEK293, His)
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Cat. No.: HY-P77536
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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FITC-Labeled Siglec-3/CD33 Protein, Human (HEK293, His-Avi)
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Cat. No.: HY-P78408
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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FITC-Labeled Siglec-3/CD33 Protein, Human (HEK293, His)
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Cat. No.: HY-P704879
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript; P67; CD33 Antigen; Sialic Acid-Binding Ig-Like Lectin 3; Siglec-3
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Siglec-3/CD33 Protein, Human (115a.a, HEK293, Fc)
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Cat. No.: HY-P704880
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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Siglec-3/CD33 Protein, Human (93a.a, HEK293, Llama Fc)
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Cat. No.: HY-P704881
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript
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Siglec-3/CD33 Protein, Human (Biotinylated, HEK293, Fc-Avi)
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Cat. No.: HY-P705113
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD33; Myeloid Cell Surface Antigen CD33; CD33 Molecule; FLJ00391; SIGLEC3; Gp67; CD33 Antigen (Gp67); CDNA FLJ50122, Highly Similar To Myeloid Cell Surface Antigen CD33; CD33rSiglec; Sialic Acid Binding Ig-Like Lectin 3; SIGLEC-3; CD33 Molecule Transcript; P67; CD33 Antigen; Sialic Acid-Binding Ig-Like Lectin 3; Siglec-3
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
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Capetin (28-54), human
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- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
