1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite

Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Endogenous Metabolite Related Products (541):

Cat. No. Product Name Effect Purity
  • HY-19312
    3-Methyladenine 99.84%
    3-Methyladenine is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K.
  • HY-N0583
    Hydrocortisone 99.66%
    Hydrocortisone is a steroid hormone or glucocorticoid secreted by the adrenal cortex.
  • HY-B0215
    Acetylcysteine >98.0%
    Acetylcysteine is used mainly as a mucolytic, which protects against acetaminophen overdose-induced hepatotoxicity by maintaining or restoring hepatic concentrations of glutathione.
  • HY-14649
    Retinoic acid 98.36%
    Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM.
  • HY-10002
    Calcitriol 99.81%
    Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.
  • HY-B0447B
    L-Epinephrine >99.0%
    L-Epinephrine is a hormone secreted by the medulla of the adrenal glands. L-Epinephrine is an α-adrenergic and β-adrenergic receptor agonist.
  • HY-N1150
    Thymidine 99.90%
    Thymidine is a a pyrimidine deoxynucleoside.
  • HY-B1776
    Spermidine
    Spermidine, a precursor of spermine, is a polyamine derived from putrescine and could help stabilize some membranes and nucleic acid structures.
  • HY-B0141
    Estradiol 98.45%
    Estradiol is a human sex hormone and steroid, and the primary female sex hormone.
  • HY-B0075
    Melatonin >98.0%
    Melatonin, a hormone produced in the brain, is a potent melatonin receptor activator, and possesses important antioxidative and anti-inflammatory properties.
  • HY-101952
    Prostaglandin E2 98.01%
    Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
  • HY-B0150
    Nicotinamide >98.0%
    Nicotinamide is a water-soluble vitamin, an active component of coenzymes NAD and NADP, and acts as poly (ADP-ribose) polymerase (PARP) inhibitor.
  • HY-66005
    Acetaminophen 99.69%
    Acetaminophen (paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic drug.
  • HY-B0131
    Prostaglandin E1 >98.0%
    Prostaglandin E1 (PGE1) is a potent vasodilator and activates the prostaglandin E1 (EP) receptor.
  • HY-B2176
    ATP 99.18%
    ATP is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells.
  • HY-14650
    DHEA >98.0%
    DHEA is an important source of androgens, and is an effective antiapoptotic factor.
  • HY-N0437
    Progesterone 98.79%
    Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
  • HY-B1618
    Corticosterone 99.29%
    Corticosterone is a sensitive inhibitor of monoamine transport.
  • HY-12033
    2-Methoxyestradiol 99.54%
    2-Methoxyestradiol is a microtubule and HIF-1 inhibitor, binds to tubulin at or near the colchicine site and inhibits the polymerization of tubulin in vitro, works by interfering with normal microtubule function.
  • HY-B2167
    Docosahexaenoic Acid
    Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
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