5142-23-4
5142-23-4
Chemical Structure
3-Methyladenine
Synonym(s): 3-MA
- CAS No.: 5142-23-4
- Formula:C6H7N5
- Molecular Weight:149.15
IUPAC Name: 3-methyl-3H-purin-6-amine
InChIKey: FSASIHFSFGAIJM-UHFFFAOYSA-N
SMILES: NC1=C2N=CN=C2N(C)C=N1
Biological Activity: 3-Methyladenine (3-MA) is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K[1].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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3-Methyladenine | 99.91% | 3-Methyladenine (3-MA) is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K. | ||||||||||||||||||||
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3-Methyladenine (Standard) | ≥98% | 3-Methyladenine (Standard) is the analytical standard of 3-Methyladenine. This product is intended for research and analytical applications. 3-Methyladenine (3-MA) is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K. | ||||||||||||||||||||
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3-Methyladenine-d3 | 98.98% | 3-Methyladenine-d3 is the deuterium labeled 3-Methyladenine. 3-Methyladenine (3-MA) is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K. | ||||||||||||||||||||
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3-Methyladenine-d3 hydroiodide | 3-Methyladenine-d3 (hydroiodide) is deuterated labeled 3-Methyladenine. | |||||||||||||||||||||
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(Z)-9-Propenyladenine | 97.21% | (Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral agent known as nucleotide analogue reverse transcriptase (NtART) inhibitor, which blocks reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV. | ||||||||||||||||||||
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9-Propenyladenine (Standard) | ≥98% | 9-Propenyladenine (Standard) (Mutagenic Impurity of Tenofovir Disoproxil (Standard); Tenofovir Impurity 2 (Standard)) is the analytical standard of 9-Propenyladenine (HY-100079). This product is intended for research and analytical applications. 9-Propenyladenine (Mutagenic impurity of tenofovir disoproxil) is a purine derivative mutagenic impurity of Tenofovir Disoproxil (HY-13782A), and also serves as a capping group intermediate in the synthesis of N-substituted purines. | ||||||||||||||||||||
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1-Methyladenine | 99.99% | 1-Methyladenine is a gonad maturation-promoting regulator. 1-Methyladenine is produced in testes and ovarian follicle cells of starfish under the induction of gonad-stimulating substance (GSS). 1-Methyladenine promotes starfish oocyte maturation and spawning, and modifies bases that regulate DNA structure. 1-Methyladenine converts T-A base pairs in double-stranded DNA into non-disruptive T (anti)m1A (syn) Hoogsteen conformation. If this conformational base is not repaired in a timely manner, 1-Methyladenine transforms into cytotoxic DNA damage and blocks the replication process. | ||||||||||||||||||||
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7-Methylguanine-d3 | 7-Methylguanine-d3 is the deuterium labeled 7-Methylguanine. 7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents, and used as a probe of protein–DNA interactions and a key component of DNA sequencing method. | |||||||||||||||||||||
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7-Methyladenine | 98.13% | 7-Methyladenine (N7-Methyladenine), a methylated analog of Adenine (HY-B0152), is a biomarker of DNA damage from exposure to methylating agents. | ||||||||||||||||||||
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9-Ethyladenine | 99.79% | 9-Ethyladenine is a precursor of competitive antagonists of adenosine receptors (A1, A2, A3), with no significant inhibitory effect on adenine phosphoribosyltransferase (APRT). 9-Ethyladenine derivatives have high affinity and selectivity for A1 (Ki=27 nM), A2A (Ki=46 nM), and A3 (Ki=86 nM) receptors. 9-Ethyladenine does not inhibit brain APRT activity, can be used in the study of adenosine receptor-related diseases (such as nervous system diseases) models. | ||||||||||||||||||||
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9-Ethyladenine (Standard) | ≥98% | 9-Ethyladenine (Standard) is the analytical standard of 9-Ethyladenine (HY-119413). This product is intended for research and analytical applications. 9-Ethyladenine is a precursor of competitive antagonists of adenosine receptors (A1, A2, A3), with no significant inhibitory effect on adenine phosphoribosyltransferase (APRT). 9-Ethyladenine derivatives have high affinity and selectivity for A1 (Ki=27 nM), A2A (Ki=46 nM), and A3 (Ki=86 nM) receptors. 9-Ethyladenine does not inhibit brain APRT activity, can be used in the study of adenosine receptor-related diseases (such as nervous system diseases) models. | ||||||||||||||||||||
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Adenine | 99.99% | Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis. | ||||||||||||||||||||
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Adenine-13C | 99.06% | Adenine-13C is the 13C labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis. | ||||||||||||||||||||
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Adenine monohydrochloride hemihydrate | 99.87% | Adenine (6-Aminopurine) monohydrochloride hemihydrate, a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine monohydrochloride hemihydrate acts as a chemical component of DNA and RNA. Adenine monohydrochloride hemihydrate also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis. | ||||||||||||||||||||
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Adenine monohydrochloride hemihydrate (Standard) | ≥98% | Adenine monohydrochloride hemihydrate (Standard) is the analytical standard of Adenine monohydrochloride hemihydrate (HY-W015213). This product is intended for research and analytical applications. Adenine monohydrochloride hemihydrate is a hydrochloride derivative of Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis. | ||||||||||||||||||||
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Tenofovir impurity 12 | Tenofovir impurity 12 is an impurity of Tenofovir. | |||||||||||||||||||||
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3-Ethyl-3H-purin-6-amine-d5 | 3-Ethyl-3H-purin-6-amine-d5 (3-Ethyl adenine-d5) is the deuterium labeled 3-Ethyl-3H-purin-6-amine (HY-W720432). | |||||||||||||||||||||
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9-Methyl Adenine-d3 | 9-Methyl Adenine-d3 is the deuterium labeled 9-Methyladenine (HY-131117). | |||||||||||||||||||||
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[2-(6-Amino-9H-purin-9-yl)ethanol-d4 | [2-(6-Amino-9H-purin-9-yl)ethanol-d4 is the deuterium labeled 9-(2-Hydroxyethyl)adenine (HY-W105677). | |||||||||||||||||||||
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