7-Methyladenine
Based on 1 Customer Validation
7-Methyladenine (N7-Methyladenine), a methylated analog of Adenine (HY-B0152), is a biomarker of DNA damage from exposure to methylating agents.
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- Pureza : 98.13%
- No. CAS: 935-69-3
- Fòrmula: C6H7N5
- Peso molecular:149.16
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Almacenamiento:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
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HY-B0152
AdenineNucleobase -
HY-B0152R
Adenine (Standard)Nucleobase -
HY-W105677
Tenofovir impurity 24Drug Impurity -
HY-116887
N6-MethyladeninePurine -
HY-116887R
N6-Methyladenine (Standard)Purine -
HY-124143
IsoguanineGuanine Isomer -
HY-W007367
2,6-DichloropurineIntermediate -
HY-W002924
6-Chloro-2-fluoro-9H-purineBiochemical Reagent
Actividad biológica
Descripciòn
In Vitro
The higher acidity of 7-Methyladenine leads to its enzymatic cleavage from damaged DNA, and due their instability as nucleosides, it is therefore possible to isolate and determine these methyladenines as simple nucleobases[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 935-69-3
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Appearance Solid
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Peso molecular 149.16
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Fòrmula C6H7N5
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Color Light yellow to yellow
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SMILES
NC1=C2N(C=NC2=NC=N1)C
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Synonyms
N7-Methyladenine
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvente y solubilidad
In Vitro:
DMSO : 5.56 mg/mL (37.28 mM; ultrasonic and warming and adjust pH to 3 with 1M HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 2.5 mg/mL (16.76 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (278 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 6.7042 mL | 33.5211 mL | 67.0421 mL | 167.6053 mL |
| 5 mM | 1.3408 mL | 6.7042 mL | 13.4084 mL | 33.5211 mL | |
| 10 mM | 0.6704 mL | 3.3521 mL | 6.7042 mL | 16.7605 mL | |
| 15 mM | 0.4469 mL | 2.2347 mL | 4.4695 mL | 11.1737 mL | |
| DMSO | 20 mM | 0.3352 mL | 1.6761 mL | 3.3521 mL | 8.3803 mL |
| 25 mM | 0.2682 mL | 1.3408 mL | 2.6817 mL | 6.7042 mL | |
| 30 mM | 0.2235 mL | 1.1174 mL | 2.2347 mL | 5.5868 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
7-Methyladenine Related Classifications
HY-116496 Related Classifications
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