2. Induced Disease Models Products Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. Endocrine and Metabolic Disease Models Urinary System Disease Models DNA/RNA Synthesis Endogenous Metabolite
  4. High Uric Acid Models
  5. Adenine

Adenine  (Synonyms: 6-Aminopurine; Vitamin B4)

Cat. No.: HY-B0152 Purity: ≥98.0%
COA Handling Instructions

Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

For research use only. We do not sell to patients.

Adenine Chemical Structure

Adenine Chemical Structure

CAS No. : 73-24-5

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Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 55 In-stock
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Solid
500 mg USD 50 In-stock
1 g USD 60 In-stock
5 g USD 72 In-stock
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Based on 6 publication(s) in Google Scholar

Other Forms of Adenine:

Adenine Related Antibodies

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Description

Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

Microbial Metabolite

 

In Vivo

Adenine can be used in animal modeling to construct high uric acid models.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

135.13

Appearance

Solid

Formula

C5H5N5
CAS No.
SMILES

NC1=C2N=CNC2=NC=N1
Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

1M HCl : 20 mg/mL (148.01 mM; Need ultrasonic)

DMSO : ≥ 10 mg/mL (74.00 mM)

H2O : 2 mg/mL (14.80 mM; ultrasonic and warming and heat to 60°C)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.4003 mL 37.0014 mL 74.0028 mL
5 mM 1.4801 mL 7.4003 mL 14.8006 mL
10 mM 0.7400 mL 3.7001 mL 7.4003 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 1 mg/mL (7.40 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (254 KB) HNMR (116 KB) LCMS (258 KB)

Handling Instructions (2659 KB)
References
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Adenine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Adenine73-24-56-Aminopurine Vitamin B4Vitamin B4Vitamin B 4Vitamin B-4DNA/RNA SynthesisEndogenous MetabolitepurineDNAnucleobaseInhibitorinhibitorinhibit

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