Adenine-15N5 hydrochloride hydrate
Adenine-15N5 (6-Aminopurine-15N5) hydrochloride hydrate is the 15N-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
For research use only. We do not sell to patients.
- Formula: C5H6Cl15N5.1/2H2O
- Molecular Weight:194.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All DNA/RNA Synthesis Isoforms
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Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 2922-28-3
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Molecular Weight 194.57
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Formula C5H6Cl15N5.1/2H2O
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SMILES
[15NH2]C1=C2C([15NH]C=[15N]2)=[15N]C=[15N]1.Cl.O.[1/2]
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Synonyms
6-Aminopurine-15N5 hydrochloride hydrate; Vitamin B4-15N5 hydrochloride hydrate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. ORO J, et al. Synthesis of purines under possible primitive earth conditions. I. Adenine from hydrogen cyanide. Arch Biochem Biophys. 1961 Aug;94:217-27. [Content Brief]
[3]. Reader V. The assay of vitamin B(4). Biochem J. 1930;24(6):1827-31. [Content Brief]
[4]. Yung-Jen Tsai, et al. Pharmacokinetics of Adenosine and Cordycepin, a Bioactive Constituent of Cordyceps sinensis in Rat. J Agric Food Chem 2010 Apr 28;58(8):4638-43. [Content Brief]
[5]. Fatma F Mohamed, et al. Dentoalveolar Alterations in an Adenine‐Induced Chronic Kidney Disease Mouse Model. J Bone Miner Res. 2023 Aug;38(8):1192-1207. [Content Brief]
[6]. Chien-Ning Hsu, et al. Sodium Thiosulfate Improves Hypertension in Rats with Adenine-Induced Chronic Kidney Disease. Antioxidants (Basel). 2022 Jan 11;11(1):147. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Adenine-15N5 hydrochloride hydrate Related Classifications
HY-B0152S7 Related Classifications
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