- Oligonucleotides
- Phosphoramidites
- Adenine
Adenine
-
Adenine (121)
- Formula: C48H54N7O8P
- Molecular Weight: 887.96
2'-OMe-A(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.
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- Formula: C47H52N7O7P
- Molecular Weight: 857.93
DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA.
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- Formula: C38H35N5O7
- Molecular Weight: 673.71
5'-O-DMT-Bz-rA is an intermediate for cyclic di-nucleotide compounds synthesis.
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- Formula: C53H66N7O8PSi
- Molecular Weight: 988.19
Bz-rA Phosphoramidite (DMT-2'O-TBDMS-rA(bz) Phosphoramidite) a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis.
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- Formula: C38H34FN5O6
- Molecular Weight: 675.70
DMT-2'-F-Bz-dA is a phosphoramidite monomer that can be used for oligonucleotide synthesis.
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- Formula: C52H72N7O9PSi
- Molecular Weight: 998.23
2'-O-TOM-adenosine-(N-Ac)-3'-CEP is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- Formula: C49H54N7O8P
- Molecular Weight: 899.97
5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) is a nucleoside phosphoramidite monomer used to synthesize locked nucleic acid (LNA) analog oligonucleotides. It can be used as a building block of antisense oligonucleotides (ASOs) to target complementary RNA sequences. 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) locks the furanose ring into an N-type conformation through 2',4'-constrained ethyl (cEt) modification, enhancing hybridization affinity and mismatch discrimination with RNA, while significantly improving the resistance of oligonucleotides to exonuclease digestion. 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) mediates RNase H-dependent mRNA degradation or inhibits translation by forming a stable hybrid with RNA, thereby achieving gene expression regulation. 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) is mainly used in the development of antisense drugs, gene function research and oligonucleotide synthesis related to disease treatment.
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- Formula: C47H51FN7O7P
- Molecular Weight: 875.92
DMT-2'fluoro-da(bz) amidite is a key intermediate for synthesizing antisense oligonucleotides with high nuclease resistance, high RNA binding affinity, and maintained base-pair specificity.
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- Formula: C69H96N7O8P
- Molecular Weight: 1182.52
DMTr-2'-O-C22-rA-3'-CE-Phosphoramidite is an RNA phosphoramidite monomer. DMTr-2'-O-C22-rA-3'-CE-Phosphoramidite allows site-specific introduction of a 2'-O-C22 lipophilic modification at adenosine positions to construct double-stranded RNA (dsRNA) molecules with extrahepatic delivery capability. DMTr-2'-O-C22-rA-3'-CE-Phosphoramidite supports target gene silencing in skeletal muscle, cardiac muscle and adipose tissue by enhancing the lipophilicity and tissue uptake efficiency of dsRNA. DMTr-2'-O-C22-rA-3'-CE-Phosphoramidite can be used for the construction and mechanism research of nucleic acid silencing molecules.
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- Formula: C44H49N5O7Si
- Molecular Weight: 787.97
5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine is an adenosine derivative and can be used as an intermediate for oligonucleotides synthesis.
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- Formula: C50H58N7O9P
- Molecular Weight: 932.01
DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenine nucleoside analog. DMT-2'-O-MOE-rA(Bz) phosphoramidite can be used in research on oligonucleotide synthesis.
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- Formula: C47H51FN7O7P
- Molecular Weight: 875.92
2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
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- Formula: C48H52N7O8P
- Molecular Weight: 885.94
LNA-A (Bz) amidite is a phosphoramidite monomer applicable for oligonucleotide synthesis, such as the synthesis of miniature LNA anti-miRNA-122 antisense oligonucleotides.
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- Formula: C41H50N7O6P
- Molecular Weight: 767.85
N6-Methyl-dA phosphoramidite can be used in the synthesis of oligodeoxyribonucleotides.
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- Formula: C48H54N7O8P
- Molecular Weight: 887.96
DMT-dA(PAc) Phosphoramidite is a dIPhosphoramidite and can be used for DNA or RNA synthesis.
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- Formula: C44H49N5O7Si
- Molecular Weight: 787.97
5'-DMT-3'-TBDMS-Bz-rA is a nucleoside with protective and modification effects.
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- Formula: C47H64N7O7PSi
- Molecular Weight: 898.11
N6-Me-rA Phosphoramidite is a TBDMS-protected nucleoside phosphoramidite, which can be used to create oligonucleotides.
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- Formula: C39H37N5O7
- Molecular Weight: 687.74
DMT-OMe-rA(Bz) is a nucleoside analog.
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- Formula: C48H53FN7O7P
- Molecular Weight: 889.95
DMT-2'-F-dA(bz) phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- Formula: C53H66N7O8PSi
- Molecular Weight: 988.19
3'-TBDMS-Bz-rA Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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