3'-TBDMS-Bz-rA Phosphoramidite
Based on 1 Customer Validation
3'-TBDMS-Bz-rA Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
For research use only. We do not sell to patients.
- Purity: 98.38%
- CAS No.: 129451-75-8
- Formula: C53H66N7O8PSi
- Molecular Weight:988.19
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
All DNA/RNA Synthesis Isoforms
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Biological Activity
Oligonucleotides are a class of short-chain nucleic acids composed of deoxyribonucleotides or ribonucleotides; by adhering to the principle of complementary base pairing, they can pair with DNA, mRNA, or pre-mRNA to precisely "silence" specific genes, thereby inhibiting the expression of numerous proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 129451-75-8
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Appearance Solid
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Molecular Weight 988.19
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Formula C53H66N7O8PSi
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Color White to off-white
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SMILES
N#CCCOP(O[C@@H]1[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](COC(C2=CC=C(OC)C=C2)(C3=CC=CC=C3)C4=CC=C(OC)C=C4)O[C@H]1N5C=NC6=C5N=CN=C6NC(C7=CC=CC=C7)=O)N(C(C)C)C(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (101.20 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (250 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0120 mL | 5.0598 mL | 10.1195 mL | 25.2988 mL |
| 5 mM | 0.2024 mL | 1.0120 mL | 2.0239 mL | 5.0598 mL | |
| 10 mM | 0.1012 mL | 0.5060 mL | 1.0120 mL | 2.5299 mL | |
| 15 mM | 0.0675 mL | 0.3373 mL | 0.6746 mL | 1.6866 mL | |
| 20 mM | 0.0506 mL | 0.2530 mL | 0.5060 mL | 1.2649 mL | |
| 25 mM | 0.0405 mL | 0.2024 mL | 0.4048 mL | 1.0120 mL | |
| 30 mM | 0.0337 mL | 0.1687 mL | 0.3373 mL | 0.8433 mL | |
| 40 mM | 0.0253 mL | 0.1265 mL | 0.2530 mL | 0.6325 mL | |
| 50 mM | 0.0202 mL | 0.1012 mL | 0.2024 mL | 0.5060 mL | |
| 60 mM | 0.0169 mL | 0.0843 mL | 0.1687 mL | 0.4216 mL | |
| 80 mM | 0.0126 mL | 0.0632 mL | 0.1265 mL | 0.3162 mL | |
| 100 mM | 0.0101 mL | 0.0506 mL | 0.1012 mL | 0.2530 mL |