DMT-2'O-Methyl-rC(tac) phosphoramidite

Cat. No.: HY-21713: FAQs
Data Sheet SDS COA Handling Instructions

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DMT-2'O-Methyl-rC(tac) Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

For research use only. We do not sell to patients.

DMT-2'O-Methyl-rC(tac) phosphoramidite Chemical Structure

CAS No. : 179486-26-1

Size	Price	Stock	Quantity
250 mg	USD 25	In-stock	Estimated Time of Arrival: December 31
1 g	USD 54	In-stock	Estimated Time of Arrival: December 31
5 g	USD 248	In-stock	Estimated Time of Arrival: December 31
10 g		Get quote
50 g		Get quote

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Description

DMT-2'O-Methyl-rC(tac) Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

Molecular Weight

950.07

Formula

C₅₂H₆₄N₅O₁₀P

CAS No.

179486-26-1

Appearance

Solid

Color

White to off-white

SMILES

COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](O[P@](N(C(C)C)C(C)C)OCCC#N)[C@@H](OC)[C@H](N5C(N=C(NC(COC6=CC=C(C(C)(C)C)C=C6)=O)C=C5)=O)O4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (105.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0526 mL	5.2628 mL	10.5255 mL
5 mM	0.2105 mL	1.0526 mL	2.1051 mL
10 mM	0.1053 mL	0.5263 mL	1.0526 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

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Data Sheet (248 KB) SDS (393 KB)

COA (258 KB) HNMR (222 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.0526 mL	5.2628 mL	10.5255 mL	26.3139 mL
	5 mM	0.2105 mL	1.0526 mL	2.1051 mL	5.2628 mL
	10 mM	0.1053 mL	0.5263 mL	1.0526 mL	2.6314 mL
	15 mM	0.0702 mL	0.3509 mL	0.7017 mL	1.7543 mL
	20 mM	0.0526 mL	0.2631 mL	0.5263 mL	1.3157 mL
	25 mM	0.0421 mL	0.2105 mL	0.4210 mL	1.0526 mL
	30 mM	0.0351 mL	0.1754 mL	0.3509 mL	0.8771 mL
	40 mM	0.0263 mL	0.1316 mL	0.2631 mL	0.6578 mL
	50 mM	0.0211 mL	0.1053 mL	0.2105 mL	0.5263 mL
	60 mM	0.0175 mL	0.0877 mL	0.1754 mL	0.4386 mL
	80 mM	0.0132 mL	0.0658 mL	0.1316 mL	0.3289 mL
	100 mM	0.0105 mL	0.0526 mL	0.1053 mL	0.2631 mL