1. Recombinant Proteins
  2. Enzymes & Regulators
  3. Serine/Threonine Kinase Proteins
  4. Checkpoint Kinase 2 (Chk2)

Checkpoint Kinase 2 (Chk2)

Cat. No. Product Name / Synonyms Species Source
  • HY-P75349
    CHEK2 Protein, Human (sf9, GST)

    Serine/threonine-protein kinase Chk2; Hucds1; Checkpoint kinase 2; CDS1; CHK2; RAD53

    Human Sf9 insect cells
    The CHEK2 protein is a serine/threonine protein kinase that critically coordinates checkpoint-mediated cell cycle arrest, DNA repair activation, and apoptosis in response to DNA double-strand breaks. Activated CHEK2 phosphorylates CDC25A, CDC25B, and CDC25C, inhibiting their phosphatase activities and preventing the CDK-cyclin complex from activating cell cycle progression. CHEK2 Protein, Human (sf9, GST) is the recombinant human-derived CHEK2 protein, expressed by Sf9 insect cells , with GST labeled tag.
  • HY-P75348
    CHEK2 Protein, Mouse (sf9, His-GST)

    Serine/threonine-protein kinase Chk2; Hucds1; Checkpoint kinase 2; CDS1; CHK2; RAD53

    Mouse Sf9 insect cells
    CHEK2 is a serine/threonine protein kinase that coordinates cellular responses to DNA double-strand breaks by activating cell cycle arrest, DNA repair, and apoptosis. It phosphorylates effectors and inhibits CDC25A, CDC25B, and CDC25C, thereby enhancing CDK cyclin inhibition and cell cycle arrest. CHEK2 Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived CHEK2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of CHEK2 Protein, Mouse (sf9, His-GST) is 546 a.a., with molecular weight of ~90 kDa.
Cat. No. Product Name Effect Purity