Signaling Pathway

Na+/K+ ATPase

Na+/K+ ATPase

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Na+/K+ ATPase Inhibitors & Modulators (10)

Product Name Catalog No. Brief Description
Chlorpropamide

HY-B1429

Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).

Digitoxin

HY-B1357

Digitoxin is an effective Na+/K+-ATPase inhibitor, the EC50 value of Digitoxin is 0.78 μM.

Digoxin

HY-B1049

Digoxin is occasionally used in the treatment of various heart conditions, namely atrial fibrillation, atrial flutter and sometimes heart failure that cannot be controlled by other medication.

Istaroxime

HY-15718

Istaroxime(PST2744) is a positive inotropic agent that mediates its action through inhibition of sodium/potassium adenosine triphosphatase (Na+/K+ ATPase).

Istaroxime hydrochloride

HY-15718A

Istaroxime Hcl(PST-2744 Hcl) is a positive inotropic agent that mediates its action through inhibition of sodium/potassium adenosine triphosphatase (Na+/K+ ATPase).

Ouabain Octahydrate

HY-B0542

Ouabain Octahydrate inhibits Na(+)/K(+) ATPase, regulates transcription of MDR and MRP.

Prilocaine

HY-B0137

Prilocaine is a local anesthetic of the amino amide type.

Prilocaine hydrochloride

HY-B0137A

Prilocaine hydrochloride is a local anesthetic of the amino amide type.

Rostafuroxin

HY-12283

Rostafuroxin(PST 2238) is a antihypertensive compound; Na,K-ATPase antognist;displaced [3H]ouabain from the dogkidney Na+,K+-ATPase with IC50 of 1.5 nM.

Suloctidil

HY-B1237

Suloctidil is a new drug that is currently being evaluated in many clinical trials for use in dementia and thrombotic disorders.