1. Membrane Transporter/Ion Channel
    Metabolic Enzyme/Protease
  2. Na+/K+ ATPase
    Drug Metabolite
  3. Deslanoside

Deslanoside (Synonyms: Deacetyllanatoside C; Desacetyllanatoside C)

Cat. No.: HY-A0154
Handling Instructions

Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation. Deslanoside inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations .

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Deslanoside Chemical Structure

Deslanoside Chemical Structure

CAS No. : 17598-65-1

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10 mM * 1 mL in DMSO USD 364 In-stock
Estimated Time of Arrival: December 31
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Estimated Time of Arrival: December 31
10 mg USD 350 In-stock
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Description

Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation. Deslanoside inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations [1][2][3].

In Vitro

Deslanoside (Desacetyllanatoside C) is a metabolite of Lanatoside C[4]. Deslanoside increases forearm blood flow and cardiac index and decreased heart rate concomitant with a marked decrease in skeletal muscle sympathetic nerve activity measured as an indicator of centrally mediated sympathetic nervous system activity[1].

Molecular Weight

943.08

Formula

C₄₇H₇₄O₁₉

CAS No.

17598-65-1

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Keywords:

DeslanosideDeacetyllanatoside CDesacetyllanatoside CNa+/K+ ATPaseDrug MetaboliteSodium potassium pumpcardiacglycosideheartfailuresupraventriculararrhythmiasrateInhibitorinhibitorinhibit

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Deslanoside
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