Signaling Pathway

RIP kinase

RIP kinase

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RIP kinase Inhibitors & Modulators (7)

Product Name Catalog No. Brief Description
GSK'481

HY-100131

GSK'481 can inhibit RIP1 WT S166 phosphorylation in human vs mouse plasmids overexpressed in HEK293T cells.

GSK583

HY-100339

GSK583 is a highly potent and selective inhibitor of RIP2 Kinase.

Necrostatin-1

HY-15760

Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM.

RIP2 kinase inhibitor 1

HY-19764

RIP2 kinase inhibitor 1 is a receptor interacting protein-2 (RIP2) kinase inhibitor extracted from patent WO/2014043446 A1, compound example 1.

RIP2 kinase inhibitor 2

HY-19761

RIP2 kinase inhibitor 2 is a receptor interacting protein-2 (RIP2) kinase inhibitor extracted from patent WO/2014043437 A1, compound example 9.

RIPA-56

HY-101032

RIPA-56 is a highly potent, selective, and metabolically stable inhibitor of receptor-interacting protein 1 (RIP1) with an IC50 of 13 nM.

WEHI-345

HY-18937

WEHI-345 is a potent and selective inhibitor of RIPK2, with IC50 of 0.13 μM.