1. Apoptosis
  2. RIP kinase
  3. GSK963

GSK963 

Cat. No.: HY-103028A Purity: 98.57%
Handling Instructions

GSK963 is a chiral, highly potent and selective inhibitor of RIP1 kinase, with an IC50 of 29 nM. GSK963 is a selective and potent inhibitor of necroptosis in murine and human cells in vitro.

For research use only. We do not sell to patients.

GSK963 Chemical Structure

GSK963 Chemical Structure

CAS No. : 2049868-46-2

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 165 In-stock
Estimated Time of Arrival: December 31
5 mg USD 150 In-stock
Estimated Time of Arrival: December 31
10 mg USD 250 In-stock
Estimated Time of Arrival: December 31
25 mg USD 480 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

GSK963 is a chiral, highly potent and selective inhibitor of RIP1 kinase, with an IC50 of 29 nM. GSK963 is a selective and potent inhibitor of necroptosis in murine and human cells in vitro[1].

IC50 & Target

IC50: 29 nM (RIP1 in FP binding assay)[1].

Molecular Weight

230.31

Formula

C₁₄H₁₈N₂O

CAS No.

2049868-46-2

SMILES

CC(C)(C)C(N1N=CC[[email protected]]1C2=CC=CC=C2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

GSK963GSK 963GSK-963RIP kinaseReceptor-interacting protein kinasesRIPKInhibitorinhibitorinhibit

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GSK963
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HY-103028A
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