1. Apoptosis
  2. RIP kinase
  3. GSK963

GSK963 

Cat. No.: HY-103028A
Handling Instructions

GSK963 is a chiral, highly potent and selective inhibitor of RIP1 kinase, with an IC50 of 29 nM. GSK963 is a selective and potent inhibitor of necroptosis in murine and human cells in vitro.

For research use only. We do not sell to patients.

GSK963 Chemical Structure

GSK963 Chemical Structure

CAS No. : 2049868-46-2

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Description

GSK963 is a chiral, highly potent and selective inhibitor of RIP1 kinase, with an IC50 of 29 nM. GSK963 is a selective and potent inhibitor of necroptosis in murine and human cells in vitro[1].

IC50 & Target

IC50: 29 nM (RIP1 in FP binding assay)[1].

Molecular Weight

230.31

Formula

C₁₄H₁₈N₂O

CAS No.

2049868-46-2

SMILES

CC(C)(C)C(N1N=CC[[email protected]]1C2=CC=CC=C2)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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GSK963
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HY-103028A
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