2049868-46-2
2049868-46-2
Chemical Structure
GSK963
- CAS No.: 2049868-46-2
- Formula:C14H18N2O
- Molecular Weight:230.31
IUPAC Name: (S)-2,2-dimethyl-1-(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)propan-1-one
InChIKey: NJQVSLWJBLPTMD-LBPRGKRZSA-N
SMILES: CC(C)(C)C(N1N=CC[C@H]1C2=CC=CC=C2)=O
Biological Activity: GSK963 is a chiral, highly potent and selective inhibitor of RIP1 kinase, with an IC50 of 29 nM. GSK963 is a selective and potent inhibitor of necroptosis in murine and human cells in vitro[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GSK963 | 99.10% | GSK963 is a chiral, highly potent and selective inhibitor of RIP1 kinase, with an IC50 of 29 nM. GSK963 is a selective and potent inhibitor of necroptosis in murine and human cells in vitro. | ||||||||||||||||||||
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GSK963 (Standard) | ≥98% | GSK963 (Standard) is the analytical standard of GSK963 (HY-103028A). This product is intended for research and analytical applications. GSK963 is a chiral, highly potent and selective inhibitor of RIP1 kinase, with an IC50 of 29 nM. GSK963 is a selective and potent inhibitor of necroptosis in murine and human cells in vitro. | ||||||||||||||||||||
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References
Keywords
