IGFBP-2
IGFBP-2, encoded by the IGFBP2 gene, is the second most abundant IGF-binding protein in adult circulation and the dominant one in fetal serum. It carries IGFs through the bloodstream and interacts with cell surfaces through an RGD motif that engages integrins, allowing IGF-dependent and IGF-independent signaling. IGFBP-2 is prominent during development and in injury repair, and it is one of the few IGFBPs frequently upregulated in malignancy: elevated serum and tissue levels correlate with progression in glioma, prostate, colorectal and hepatocellular cancers, where it has been explored as a biomarker. IGFBP-2 also influences bone metabolism and adiposity in metabolic studies.
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IGFBP-2 Recombinant Proteins (4)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
