2. Isotope-Labeled Compounds
  3. Isotope-Labeled Steroids

Isotope-Labeled Steroids

Steroids are biologically active organic compounds with four rings arranged in a specific molecular configuration, three six-membered cyclohexane rings ( rings A, B and C ) and one five-member cyclopentane ring ( ring D). Steroid compounds mainly include sterols, bile acids and bile alcohols, steroid hormones, and steroid drugs etc. MedChemExpress ( MCE ) offers a broad range of Stable Isotope-Labeled Steroids which can be used as internal standards for the accurate quantitative GC/LC-MS analysis and involved in metabolomics.

Isotope-Labeled Steroids (365):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0322S
    Cholesterol-d7 83199-47-7 99.95%
    Cholesterol-d7 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.
    Cholesterol-d<sub>7</sub>
  • HY-N0324S
    Cholic acid-d4 116380-66-6 99.91%
    Cholic acid-d4 is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
    Cholic acid-d<sub>4</sub>
  • HY-76847S
    Chenodeoxycholic Acid-d4 99102-69-9 99.94%
    Chenodeoxycholic Acid-d4 is the deuterium labeled Chenodeoxycholic Acid. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
    Chenodeoxycholic Acid-d<sub>4</sub>
  • HY-18569S
    3-Indoleacetic acid-d5 76937-78-5 99.76%
    3-Indoleacetic acid-d5 is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid-d5 can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates.
    3-Indoleacetic acid-d<sub>5</sub>
  • HY-101952S
    Prostaglandin E2-d4 34210-10-1 99.90%
    Prostaglandin E2-d4 is the deuterium labeled Prostaglandin E2. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
    Prostaglandin E2-d<sub>4</sub>
  • HY-N0593S
    Deoxycholic acid-d4 112076-61-6 99.80%
    Deoxycholic acid-d4 is the deuterium labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
    Deoxycholic acid-d<sub>4</sub>
  • HY-15331
    Vitamin D3-d6 118584-54-6 98.47%
    Vitamin D3-d6 (Cholecalciferol-d6 ) is the deuterium labeled Vitamin D3 (HY-15398) . Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
    Vitamin D3-d<sub>6</sub>
  • HY-B0141S1
    Estradiol-d4 66789-03-5 99.55%
    Estradiol-d4 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
    Estradiol-d<sub>4</sub>
  • HY-B0141S2
    Estradiol-d5 221093-45-4 99.73%
    Estradiol-d5 is deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
    Estradiol-d<sub>5</sub>
  • HY-N0322S5
    Cholesterol-13C2 78887-48-6 99.76%
    Cholesterol-13C2 is the 13C labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.
    Cholesterol-<sup>13</sup>C<sub>2</sub>
  • HY-N7142S
    DL-Norepinephrine-d6 hydrochloride 1219803-04-9 99.75%
    DL-Norepinephrine-d6 hydrochloride is the deuterium labeled DL-Norepinephrine hydrochloride. DL-Norepinephrine hydrochloride is an external racemic catecholamine neurotransmitter, which is an equal mixture of the left-handed (L-, with activity) and right-handed (D-, with very low or no activity) stereoisomers. DL-Norepinephrine hydrochloride after being labeled with tritium can be used as a tracer for the research on Parkinson's disease.
    DL-Norepinephrine-d<sub>6</sub> hydrochloride
  • HY-B0075S
    Melatonin-d4 66521-38-8 99.70%
    Melatonin-d4 is deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Antioxidative and anti-inflammatory properties. Melatonin is a selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation.
    Melatonin-d<sub>4</sub>
  • HY-N1423S
    Glycocholic acid-d4 1201918-15-1 99.92%
    Glycocholic acid-d4 is the deuterium labeled Glycocholic acid (HY-N1423). Glycocholic acid is a bile acid derivative. Glycocholic acid downregulates MDR1, Bcl-2, MRP1, MRP2 and FXR, upregulates Bax, p53, caspase-9, caspase-3, TGR5 and S1PR2. Glycocholic acid inhibits multidrug resistance and efflux pumps, induces mitochondrial apoptosis, and enhances chemosensitivity. Glycocholic acid modulates related bile acid receptor signaling. Glycocholic acid suppresses growth and conjugation of Enterobacteriaceae and increases their antibiotic susceptibility. Glycocholic acid can be used for the research of colon adenocarcinoma and cholangiocarcinoma (CCA).
    Glycocholic acid-d<sub>4</sub>
  • HY-B1618S
    Corticosterone-d8 1271728-07-4 99.91%
    Corticosterone-d8 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
    Corticosterone-d<sub>8</sub>
  • HY-13332
    Calcifediol-d6 78782-98-6 99.09%
    Calcifediol-d6 is the deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR ligand.
    Calcifediol-d<sub>6</sub>
  • HY-B1788S
    Taurocholic acid-d4 sodium 2410279-93-3 ≥99.0%
    Taurocholic acid-d4 (sodium) is the deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.
    Taurocholic acid-d<sub>4</sub> sodium
  • HY-N0322S1
    Cholesterol-d6 60816-17-3 99.0%
    Cholesterol-d6 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.
    Cholesterol-d<sub>6</sub>
  • HY-B0172S
    Lithocholic acid-d4 83701-16-0 99.91%
    Lithocholic acid-d4 is the deuterium labeled Lithocholic acid, which is a toxic secondary bile acid.
    Lithocholic acid-d<sub>4</sub>
  • HY-N0324S1
    Cholic acid-d5 53007-09-3 99.80%
    Cholic acid-d5 is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
    Cholic acid-d<sub>5</sub>
  • HY-N2334S
    Glycochenodeoxycholic acid-d4 1201918-16-2 99.95%
    Glycochenodeoxycholic acid-d4 is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis.
    Glycochenodeoxycholic acid-d<sub>4</sub>