2. Isotope-Labeled Compounds
  3. Isotope-Labeled Steroids

Isotope-Labeled Steroids

Steroids are biologically active organic compounds with four rings arranged in a specific molecular configuration, three six-membered cyclohexane rings ( rings A, B and C ) and one five-member cyclopentane ring ( ring D). Steroid compounds mainly include sterols, bile acids and bile alcohols, steroid hormones, and steroid drugs etc. MedChemExpress ( MCE ) offers a broad range of Stable Isotope-Labeled Steroids which can be used as internal standards for the accurate quantitative GC/LC-MS analysis and involved in metabolomics.

Isotope-Labeled Steroids (361):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0324S
    Cholic acid-d4 116380-66-6 ≥99.0%
    Cholic acid-d4 is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
    Cholic acid-d<sub>4</sub>
  • HY-15331
    VD3-d6 118584-54-6
    VD3-d6 is the deuterium labeled Vitamin D3; tools for determination of Vitamin D3 metabolites in human serum.
    VD3-d<sub>6</sub>
  • HY-B0141S1
    Estradiol-d4 66789-03-5 99.55%
    Estradiol-d4 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].
    Estradiol-d<sub>4</sub>
  • HY-18569S
    3-Indoleacetic acid-d5 76937-78-5 99.84%
    3-Indoleacetic acid-d5 is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d5 can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].
    3-Indoleacetic acid-d<sub>5</sub>
  • HY-B1788S
    Taurocholic acid-d4 sodium 2410279-93-3 99.29%
    Taurocholic acid-d4 (sodium) is the deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.
    Taurocholic acid-d<sub>4</sub> sodium
  • HY-N0322S
    Cholesterol-d7 83199-47-7 ≥98.0%
    Cholesterol-d7 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.
    Cholesterol-d<sub>7</sub>
  • HY-76847S
    Chenodeoxycholic Acid-d4 99102-69-9 99.19%
    Chenodeoxycholic Acid-d4 is the deuterium labeled Chenodeoxycholic Acid. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
    Chenodeoxycholic Acid-d<sub>4</sub>
  • HY-15330
    VD2-d3 1217448-46-8 98.60%
    VD2-d3 is the deuterium labeled vitamin D2.
    VD2-d<sub>3</sub>
  • HY-N0593S
    Deoxycholic acid-d4 112076-61-6 ≥98.0%
    Deoxycholic acid-d4 is the deuterium labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
    Deoxycholic acid-d<sub>4</sub>
  • HY-B0075S
    Melatonin-d4 66521-38-8
    Melatonin-d4 is deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4].
    Melatonin-d<sub>4</sub>
  • HY-32349S
    Ercalcidiol-d3 1217467-39-4 99.86%
    Ercalcidiol-d3 is the deuterium labeled Ercalcidiol. Ercalcidiol is a metabolite of Vitamins D2. Ercalcidiol can be used as an indicator of vitamins D status.
    Ercalcidiol-d<sub>3</sub>
  • HY-15328
    25-Hydroxy VD2-d6 1262843-46-8 98.96%
    25-Hydroxy VD2-d6 is the deuterium labeled 25-Hydroxy VD2.
    25-Hydroxy VD2-d<sub>6</sub>
  • HY-B0172S
    Lithocholic acid-d4 83701-16-0 99.72%
    Lithocholic acid-d4 is the deuterium labeled Lithocholic acid, which is a toxic secondary bile acid[1].
    Lithocholic acid-d<sub>4</sub>
  • HY-B1618S
    Corticosterone-d8 1271728-07-4 98.43%
    Corticosterone-d8 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
    Corticosterone-d<sub>8</sub>
  • HY-B0141S
    Estradiol-d3 79037-37-9 98.60%
    Estradiol-d3 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
    Estradiol-d<sub>3</sub>
  • HY-N7142S
    DL-Norepinephrine-d6 hydrochloride 1219803-04-9 99.88%
    DL-Norepinephrine-d6 (hydrochloride) is the deuterium labeled DL-Norepinephrine hydrochloride. DL-Norepinephrine hydrochloride is a synthetic phenylethylamine that mimics the sympathomimetic actions of the endogenous norepinephrine．DL-Norepinephrine hydrochloride is a neurotransmitter targets α1 and β1 adrenoceptors, has an increasing effect on subendocardial oxygen tension[1].
    DL-Norepinephrine-d<sub>6</sub> hydrochloride
  • HY-N0324S1
    Cholic acid-d5 53007-09-3 ≥98.0%
    Cholic acid-d5 is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
    Cholic acid-d<sub>5</sub>
  • HY-13332
    Calcifediol-d6 78782-98-6 98.91%
    Calcifediol-d6 is the deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR inhibitor[1][2].
    Calcifediol-d<sub>6</sub>
  • HY-N0324S2
    Cholic acid-13C 52886-36-9 ≥98.0%
    Cholic acid-13C is the 13C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
    Cholic acid-<sup>13</sup>C
  • HY-114464S1
    11-Beta-hydroxyandrostenedione-d7 2331287-27-3 ≥99.0%
    11-Beta-hydroxyandrostenedione-d7 is the deuterium labeled 11-Beta-hydroxyandrostenedione. 11-Beta-hydroxyandrostenedione (4-Androsten-11β-ol-3,17-dione) is a steroid mainly found in the the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue). 11-Beta-hydroxyandrostenedione is a 11β-hydroxysteroid dehydrogenase (11βHSD) isozymes inhibitor[1][2]
    11-Beta-hydroxyandrostenedione-d<sub>7</sub>