Taurocholic acid-d4 sodium
Based on 1 publication(s) in Google Scholar
Taurocholic acid-d4 (sodium) is the deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.
For research use only. We do not sell to patients.
- Purity: 98.21%
- CAS No.: 2410279-93-3
- Formula: C26H40D4NNaO7S
- Molecular Weight:541.71
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-76847S
Chenodeoxycholic Acid-d4
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HY-N0324
Cholic acid
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HY-N0324S
Cholic acid-d4
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HY-N1423S
Glycocholic acid-d4
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HY-B1788
Taurocholic acid
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HY-N2334S
Glycochenodeoxycholic acid-d4
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HY-N0324R
Cholic acid (Standard)
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HY-B1788R
Taurocholic acid (Standard)
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HY-114392
Gly-β-MCA
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HY-N0545R
Taurocholic acid sodium (Standard)
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HY-116084S
Trimethylamine N-oxide-d9
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HY-41324
7-keto-Deoxycholic acid
Publications Citing Use of MedChemExpress (MCE) Taurocholic acid-d4 sodium
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2410279-93-3
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Unlabeled Cas 81-24-3
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Appearance Solid
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Molecular Weight 541.71
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Formula C26H40D4NNaO7S
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Color White to off-white
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SMILES
O[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(NCCS(=O)(O[Na])=O)=O)([C@H](C[C@]2([H])[C@@]4([C@](C([2H])([2H])[C@@H](C([2H])([2H])C4)O)([H])C1)C)O)C
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Synonyms
N-Choloyltaurine-d4 sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Nature
2026 Mar;651(8104):251-259. PMID: 41606314
Solvent & Solubility
DMSO : 50 mg/mL (92.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
DMF : ≥ 25 mg/mL (46.15 mM)
Ethanol : ≥ 2 mg/mL (3.69 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Mooranian A, et al. The effect of a tertiary bile acid, taurocholic acid, on the morphology and physical characteristics of microencapsulated probucol: potential applications in diabetes: a characterization study. Drug Deliv Transl Res. 2015 Oct;5(5):511-22. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMF / DMSO | 1 mM | 1.8460 mL | 9.2300 mL | 18.4601 mL | 46.1502 mL |
| DMF / DMSO | 5 mM | 0.3692 mL | 1.8460 mL | 3.6920 mL | 9.2300 mL |
| 10 mM | 0.1846 mL | 0.9230 mL | 1.8460 mL | 4.6150 mL | |
| 15 mM | 0.1231 mL | 0.6153 mL | 1.2307 mL | 3.0767 mL | |
| 20 mM | 0.0923 mL | 0.4615 mL | 0.9230 mL | 2.3075 mL | |
| 25 mM | 0.0738 mL | 0.3692 mL | 0.7384 mL | 1.8460 mL | |
| 30 mM | 0.0615 mL | 0.3077 mL | 0.6153 mL | 1.5383 mL | |
| 40 mM | 0.0462 mL | 0.2308 mL | 0.4615 mL | 1.1538 mL | |
| DMSO | 50 mM | 0.0369 mL | 0.1846 mL | 0.3692 mL | 0.9230 mL |
| 60 mM | 0.0308 mL | 0.1538 mL | 0.3077 mL | 0.7692 mL | |
| 80 mM | 0.0231 mL | 0.1154 mL | 0.2308 mL | 0.5769 mL |
Taurocholic acid-d4 sodium Related Classifications
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