7-keto-Deoxycholic acid

Cat. No.: HY-41324 Purity: 98.32%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

7-keto-Deoxycholic acid is a metabolite of bile acids in Clostridium absonum. 7-keto-Deoxycholic acid is also converted from Lactobacillus and Bifidobacterium with specific condition.

For research use only. We do not sell to patients.

7-keto-Deoxycholic acid Chemical Structure

CAS No. : 911-40-0

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5 mg	USD 58	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 90	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 260	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 400	In-stock	Estimated Time of Arrival: December 31
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Description

7-keto-Deoxycholic acid is a metabolite of bile acids in Clostridium absonum. 7-keto-Deoxycholic acid is also converted from Lactobacillus and Bifidobacterium with specific condition^[1]^[2].

In Vitro

7-keto-Deoxycholic acid shows an increasing bioconversion rate with addition of an equimolar concentration of deoxycholic acid (which itself is not metabolized)^[1].
7-keto-Deoxycholic acid is induced by deoxycholic acid and then it's metabolized^[1].
E. lentum-like c-25 converts 81.7% of 2 mM cholic acid to deoxycholic acid and 3.7% to 7-keto-Deoxycholic acid under anaerobic incubation^[2].
E. lentum-like c-25 converts 91.5% of 150 mg/mL cholic acid to deoxycholic acid and 1.1% to 7-keto-Deoxycholic acid under anaerobic incubation^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

406.56

Formula

C₂₄H₃₈O₅

CAS No.

911-40-0

Appearance

Solid

Color

White to off-white

SMILES

O[C@@H](C[C@@](C1)2[H])CC[C@]2(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@@H]([C@H](C)CCC(O)=O)CC[C@@]4([H])[C@]3([H])C1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (245.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.4597 mL	12.2983 mL	24.5966 mL
5 mM	0.4919 mL	2.4597 mL	4.9193 mL
10 mM	0.2460 mL	1.2298 mL	2.4597 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
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μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.32%

Select Batch:

Data Sheet (274 KB) SDS (251 KB)

COA (252 KB) HNMR (261 KB) RP-HPLC (193 KB) MS (177 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.4597 mL	12.2983 mL	24.5966 mL	61.4915 mL
	5 mM	0.4919 mL	2.4597 mL	4.9193 mL	12.2983 mL
	10 mM	0.2460 mL	1.2298 mL	2.4597 mL	6.1492 mL
	15 mM	0.1640 mL	0.8199 mL	1.6398 mL	4.0994 mL
	20 mM	0.1230 mL	0.6149 mL	1.2298 mL	3.0746 mL
	25 mM	0.0984 mL	0.4919 mL	0.9839 mL	2.4597 mL
	30 mM	0.0820 mL	0.4099 mL	0.8199 mL	2.0497 mL
	40 mM	0.0615 mL	0.3075 mL	0.6149 mL	1.5373 mL
	50 mM	0.0492 mL	0.2460 mL	0.4919 mL	1.2298 mL
	60 mM	0.0410 mL	0.2050 mL	0.4099 mL	1.0249 mL
	80 mM	0.0307 mL	0.1537 mL	0.3075 mL	0.7686 mL
	100 mM	0.0246 mL	0.1230 mL	0.2460 mL	0.6149 mL

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7-keto-Deoxycholic acid911-40-0Inhibitorinhibitorinhibit

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7-keto-Deoxycholic acid