1. Screening Libraries
  2. GPCR/G Protein Compound Library

GPCR/G Protein Compound Library

Cat. No.: HY-L006
Library Contents: XLSX PDF

A unique collection of 672 small molecules targeting G protein coupled receptors used in GPCR screening for various research and drug development projects.

GPCR/G Protein Compound Library
Size (Pre-dissolved DMSO or Solid) Price Stock
30 μL/well (10 mM solution) Get quote In-stock
50 μL/well (10 mM solution) Get quote In-stock
100 μL/well (10 mM solution) Get quote In-stock
250 μL/well (10 mM solution) Get quote In-stock

Please contact us at

[email protected]

Top Publications Citing Use of Products
  • Description

  • Product Details

  • Composition

  • Contents

  • Documentation

& Advantages

•   A unique collection of 672 small molecules targeting G protein coupled receptors used in GPCR screening for various research and drug development projects.

•   Targets such as 5-HT Receptor, Dopamine Receptor, Opioid Receptor, Adrenergic Receptors, Cannabinoid Receptor, mGluR, ETA Receptor, etc.

•   The most successful class of drugable targets in the human genome and remain the most attractive family of targets.

•   All of the small molecules in the GPCR library are well characterized with biological and pharmaceutical activity. Some compounds have been approved by the FDA.

•   A powerful tool for discovering GPCR-based drugs that are the richest signal receptor targets for drug discovery.

•   Structurally diverse, medicinally active, and cell permeable.

•   Rich documentation with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure the highest purity.

•   All compounds are in stock and continuously updated.

Product Details
A collection of 672 GPCR/G Protein related compounds supplied as pre-dissolved DMSO solutions or Solid
96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Blue ice

GPCR/G Protein Compound Library

Source: MedChem Express

Contents of GPCR/G Protein Compound Library

Plate layout: HY-L006-1

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Pimavanserin tartrate Substance P (1-7)(TFA) Angiotensin II 5-valine Angiotensin II human Oxytocin (acetate) Octreotide (acetate) Histamine Desmopressin (Acetate) Terlipressin Gonadorelin (acetate) Empty
b Empty Leuprolide Acetate Alarelin (Acetate) Goserelin (acetate) Nicotinamide N-oxide L-Glutamine N-Acetylhistamine Eucalyptol Allantoin p-Hydroxycinnamic acid L-Glutamic acid monosodium salt Empty
c Empty trans-ACPD Theobromine Theophylline Flopropione Carbamoylcholine (chloride) O-Phospho-L-serine LY354740 Octopamine (hydrochloride) Dopamine (hydrochloride) Scopine (hydrochloride) Empty
d Empty Methacholine (chloride) Tolazoline (hydrochloride) Bethanechol (chloride) TCN238 Xanthotoxol (R)-(-)-Phenylephrine (hydrochloride) Synephrine (hydrochloride) SQ22536 Betahistine (dihydrochloride) (S)-MCPG Empty
e Empty (RS)-MCPG Harmine Atipamezole Methoxyphenamine (Hydrochloride) Ferulic acid (sodium) Detomidine (hydrochloride) Agmatine (sulfate) RU 24969 MPEP (Hydrochloride) BRL 54443 Empty
f Empty Melatonin VU0364770 LY404039 Cevimeline (hydrochloride) Arecoline (hydrobromide) Levodropropizine MTEP (hydrochloride) Dexmedetomidine (hydrochloride) Tetrahydrozoline (hydrochloride) Medetomidine (hydrochloride) Empty
g Empty Acefylline L-(-)-α-Methyldopa (hydrate) Proxyphylline Nomifensine CB-7921220 Moxonidine Agomelatine HOKU-81 Osthole Tasimelteon Empty
h Empty Naphazoline (hydrochloride) 8-OH-DPAT Pindolol Matrine Epinastine Alprenolol Oxidopamine (hydrobromide) Clorprenaline hydrochloride Diphylline Irsogladine Empty

Plate layout: HY-L006-2

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Eltoprazine (hydrochloride) Xylazine (hydrochloride) Ramelteon Setiptiline VU0361737 Ethamsylate Tulobuterol hydrochloride Mirtazapine Doxofylline Pemirolast (potassium) Empty
b Empty Atenolol Clonidine (hydrochloride) Sulfisoxazole VUF10460 Oncrasin-1 Piperoxan (hydrochloride) Terbutaline (sulfate) Mebhydrolin JNJ-7777120 DREADD agonist 21 Empty
c Empty Agomelatine (hydrochloride) Xylometazoline (hydrochloride) Pridopidine B-HT 920 Guanfacine (hydrochloride) Reparixin Dexpramipexole (dihydrochloride) Pramipexole (dihydrochloride) Tropicamide Tropisetron Empty
d Empty Alprenolol (hydrochloride) Zolmitriptan O-desmethyl Mebeverine alcohol (hydrochloride) Salbutamol (hemisulfate) L-Hyoscyamine Atropine Tizanidine (hydrochloride) WZ811 Guanabenz (Acetate) SKF 38393 (hydrochloride) Empty
e Empty Tripelennamine (hydrochloride) Diphenhydramine (hydrochloride) MSX-122 Dopamine serotonin antagonist-1 Amitraz PHCCC Nuciferine Pizotifen Propranolol (hydrochloride) Fenspiride (Hydrochloride) Empty
f Empty Ropinirole (hydrochloride) ST034307 AH 6809 Piribedil Vortioxetine Metoclopramide Ticlopidine (hydrochloride) Mianserin (hydrochloride) Antazoline (hydrochloride) Desipramine hydrochloride Empty
g Empty Chlorphenoxamine Lificiguat VU 0357121 Anisodamine GSK137647A CASIN Histamine (phosphate) 1A-116 DC260126 Alcaftadine Empty
h Empty Betaxolol Fingolimod NECA Sotalol (hydrochloride) BQCA ML-098 RO1138452 Desloratadine Cyclobenzaprine (hydrochloride) Olanzapine Empty

Plate layout: HY-L006-3

1 2 3 4 5 6 7 8 9 10 11 12
a Empty JWH-133 N-Desmethylclozapine Molindone (hydrochloride) Amezinium (methylsulfate) Clenbuterol (hydrochloride) ICI 118,551 (hydrochloride) Lu AF21934 Rotigotine AZD4635 Ramosetron (Hydrochloride) Empty
b Empty Moxisylyte (hydrochloride) Chlorprothixene (1R,2S)-VU0155041 CYM-5541 Pregnenolone JNJ-63533054 Metaraminol (tartrate) RS 127445 Diphenylpyraline (hydrochloride) AVex-73 hydrochloride Empty
c Empty SB-334867 (free base) Ro 67-7476 Imidafenacin Tropisetron (Hydrochloride) Promazine (hydrochloride) Asenapine (hydrochloride) Carbazochrome (sodium sulfonate) Ritodrine (hydrochloride) Cyproheptadine (hydrochloride) SCH 23390 (hydrochloride) Empty
d Empty Dolasetron JNJ16259685 UNBS5162 CP 376395 Clozapine Tranilast (trans-) Tranilast Azaperone Loxapine Carteolol (hydrochloride) Empty
e Empty ABT-239 Alosetron (Hydrochloride) Nizatidine Esmolol (hydrochloride) Pitolisant (hydrochloride) Palonosetron (Hydrochloride) L-Epinephrine (Bitartrate) BQU57 Proglumide YL0919 Empty
f Empty ZM241385 Famotidine Isoxsuprine hydrochloride Dobutamine (hydrochloride) Trihexyphenidyl (hydrochloride) Topiramate Tetrahydroberberine Pumosetrag Hydrochloride Phenoxybenzamine (hydrochloride) CP-809101 (hydrochloride) Empty
g Empty Levosulpiride VU0152100 Sulpiride (R)-5-Hydroxymethyl Tolterodine Clozapine (N-oxide) Betaxolol (hydrochloride) Levobetaxolol (hydrochloride) Fingolimod (hydrochloride) SCH 58261 Metipranolol hydrochloride Empty
h Empty Diphenidol (hydrochloride) BD1063 (dhydrochloride) Cortodoxone GW9508 Biperiden (Hydrochloride) OC000459 Acrivastine Granisetron (Hydrochloride) N6-Cyclohexyladenosine MDA 19 Empty

Plate layout: HY-L006-4

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Ranitidine (hydrochloride) Cyproheptadine (hydrochloride sesquihydrate) Clomipramine (hydrochloride) GR79236 LY334370 LY 344864 racemate LY 344864 CCR2-RA-[R] Alizapride hydrochloride rac-Rotigotine (Hydrochloride) Empty
b Empty Rotigotine (Hydrochloride) SB225002 Prostaglandin E2 Ro 10-5824 (dihydrochloride) Dimemorfan (phosphate) SB-742457 Metoclopramide (hydrochloride hydrate) Nomifensine (maleate) Seratrodast Tetrahydropalmatine Empty
c Empty Rotundine Homatropine (Bromide) SB-408124 Pheniramine (Maleate) Cinacalcet Oxybutynin Prednisone Salirasib Glucagon receptor antagonists-3 Glucagon receptor antagonists-2 Empty
d Empty Piperidolate (hydrochloride) BAY 41-2272 Prednisolone Cortisone Calcium-Sensing Receptor Antagonists I TGR5 Receptor Agonist Dapiprazole (hydrochloride) Clemizole (hydrochloride) Solifenacin Hydrocortisone Empty
e Empty TY-52156 Labetalol (hydrochloride) Adenosine 5'-monophosphate monohydrate Sinomenine hydrochloride Prucalopride Cinnarizine ADX-47273 (R)-ADX-47273 Amisulpride Piboserod Empty
f Empty VU0357017 (hydrochloride) Homatropine (methylbromide) Rebamipide Nedocromil N6-(2-Phenylethyl)adenosine Xanomeline (oxalate) Naratriptan (hydrochloride) Acebutolol (hydrochloride) N6-(4-Hydroxybenzyl)adenosine Prasugrel Empty
g Empty Volinanserin Olopatadine (hydrochloride) Methylprednisolone Haloperidol Setiptiline (maleate) Phentolamine (mesylate) Naltrexone (Hydrochloride) Ambrisentan Vortioxetine (hydrobromide) Droperidol Empty
h Empty SB-222200 Talnetant Misoprostol Loratadine PD 117519 Veralipride Quetiapine Scopolamine (hydrobromide) Fenoterol (hydrobromide) Istradefylline Empty

Plate layout: HY-L006-5

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Y16 Roxatidine (Acetate Hydrochloride) AR-M 1000390 (hydrochloride) Azasetron (hydrochloride) MK-6892 Ciproxifan (maleate) (RS)-Butyryltimolol Atropine (sulfate monohydrate) Urapidil Doxylamine (succinate) Empty
b Empty AZD1981 Triflupromazine (hydrochloride) SB-269970 (hydrochloride) Alfuzosin Diphenmanil (methylsulfate) Regadenoson Flibanserin Dexchlorpheniramine (maleate) Chlorpheniramine (maleate) Yohimbine (Hydrochloride) Empty
c Empty Rauwolscine (hydrochloride) Rizatriptan (benzoate) CTEP Latrepirdine (dihydrochloride) Dexamethasone Betamethasone Naftopidil Deoxycholic acid SB-408124 (Hydrochloride) Cinacalcet (hydrochloride) Empty
d Empty Oxybutynin (chloride) Triamcinolone SB 242084 Ketanserin Mirabegron SCH 527123 TCS-OX2-29 Methscopolamine (bromide) Glycopyrrolate Solifenacin (hydrochloride) Empty
e Empty Benzetimide (hydrochloride) MK-7622 Scopolamine N-oxide hydrobromide Zuclopenthixol Mepyramine maleate Asenapine (maleate) Fenoldopam (mesylate) Setipiprant Cortisone (acetate) Benztropine (mesylate) Empty
f Empty Bambuterol (hydrochloride) Perphenazine ONO-AE3-208 ALB-127158(a) Ozanimod Hydrocortisone (acetate) TBPB Adoprazine GPR120-IN-1 MK-0557 Empty
g Empty Carvedilol Tozadenant CPPHA Carbinoxamine maleate salt Thioridazine (hydrochloride) ML141 Terutroban Trazodone (hydrochloride) Tamsulosin CCG-203971 Empty
h Empty NPS-2143 PF-04418948 Org 27569 Forskolin Trimipramine (maleate) Pergolide (mesylate) SKF-82958 (hydrobromide) Ipratropium (bromide) Decloxizine (dihydrochloride) Noscapine Empty

Plate layout: HY-L006-6

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Sumatriptan (succinate) Lasmiditan (hydrochloride) CJ-42794 Asimadoline Deoxycholic acid sodium salt Salmeterol Puerarin Desonide Tegaserod (maleate) RS 504393 Empty
b Empty Azelastine (hydrochloride) Palosuran TC-G-1008 MRE-269 PF-3274167 Prazosin (hydrochloride) Clopidogrel (hydrogen sulfate) 4-IBP Mepenzolate (Bromide) Ocaperidone Empty
c Empty ML314 Buspirone (hydrochloride) Methylbenactyzium Bromide Riociguat Losartan Pirenzepine (dihydrochloride) Zibotentan RBC8 Trimethobenzamide hydrochloride CID 16020046 Empty
d Empty Ketotifen (fumarate) Domperidone Fevipiprant Paliperidone Iloperidone RS102895 (hydrochloride) BML-190 Mozavaptan Pimavanserin Flavoxate (hydrochloride) Empty
e Empty Trospium (chloride) AdipoRon Irbesartan ADL-5859 ZK756326 (dihydrochloride) Reparixin (L-lysine salt) Mifepristone Budesonide EHop-016 LY310762 Empty
f Empty Lafutidine (S)-Timolol (Maleate) Latanoprost Brexpiprazole Triamcinolone (acetonide) Dexamethasone (acetate) BX471 Cevimeline (hydrochloride hemihydrate) Brompheniramine (maleate) Valsartan Empty
g Empty Laropiprant Methylnaltrexone (Bromide) BD-1047 (dihydrobromide) Scopolamine (butylbromide) Candesartan ONC212 Sertindole SA4503 (dihydrochloride) Vilazodone Deflazacort Empty
h Empty Quetiapine (fumarate) Nebivolol (hydrochloride) UK 14,304 (tartrate) VU0467154 NPS-2143 (hydrochloride) BPTU Loxapine (succinate) Olmesartan MK-3697 Hydroxyzine (dihydrochloride) Empty

Plate layout: HY-L006-7

1 2 3 4 5 6 7 8 9 10 11 12
a Empty JTC-801 Aripiprazole Propantheline (bromide) TG6-10-1 SB-674042 MBX-2982 Tolvaptan GW842166X OPC-21268 K-Ras(G12C) inhibitor 12 Empty
b Empty Kobe0065 Naltrindole (hydrochloride) ST-836 (hydrochloride) Fluocinolone (Acetonide) Bay 59-3074 Cenerimod CCG-63808 CCG-1423 AMG 837 (calcium hydrate) Azilsartan Empty
c Empty AM095 (free acid) 3-Isopropyl-5-(4-(((6-(4-(methylsulfonyl)phenyl)pyridin-3-yl)oxy)methyl)piperidin-1-yl)-1,2,4-oxadiazole AMD-070 hydrochloride MLE-4901 Terazosin (hydrochloride dihydrate) Clemastine (fumarate) Alvimopan (dihydrate) Ponesimod Losartan (potassium) Loxiglumide Empty
d Empty ONO-7300243 Cetirizine (dihydrochloride) Bilastine Meclizine (dihydrochloride) Cariprazine (hydrochloride) Cisapride Sarpogrelate (hydrochloride) Mebeverine (hydrochloride) LP-211 Loteprednol Etabonate Empty
e Empty Clobetasol propionate Ziprasidone (hydrochloride monohydrate) SB 242084 (hydrochloride) Almotriptan (malate) Ebastine Dimenhydrinate TCS 1102 Desisobutyryl-ciclesonide Tiotropium (Bromide) MRS 2578 Empty
f Empty Alverine (citrate) Naftidrofuryl (oxalate) NAN-190 (hydrobromide) Methylprednisolone succinate Ki16425 SRT3190 Dinoprost (tromethamine salt) SR144528 (20S)-Protopanaxatriol Sitaxsentan (sodium) Empty
g Empty Ebrotidine APD668 Vilazodone (Hydrochloride) AM095 Taprenepag Avosentan IT1t (dihydrochloride) GSK682753A Trifluoperazine (dihydrochloride) Solifenacin (Succinate) Empty
h Empty Pranlukast PF429242 (dihydrochloride) SB-399885 hydrochloride E7046 Prednisolone (disodium phosphate) Nicergoline Prucalopride (succinate) (±)-SLV319 SB 271046 (Hydrochloride) Pranlukast (hemihydrate) Empty

Plate layout: HY-L006-8

1 2 3 4 5 6 7 8 9 10 11 12
a Empty AM966 Grapiprant Vorapaxar Fluocinonide Silodosin NS-304 Rimonabant (Hydrochloride) Rolapitant Fluticasone (propionate) Fimasartan Empty
b Empty Plerixafor Trimebutine (maleate) Preladenant AM630 Betamethasone dipropionate Ivabradine (hydrochloride) AR 231453 Nefazodone (hydrochloride) BAN ORL 24 Darifenacin (hydrobromide) Empty
c Empty Clebopride (malate) Indacaterol (maleate) Otenabant Fluphenazine (dihydrochloride) Almorexant Loperamide (hydrochloride) Baohuoside I Telmisartan Taranabant Dexamethasone phosphate disodium Empty
d Empty Siponimod AC-55541 GW-1100 Eprosartan (mesylate) Nastorazepide Beclometasone dipropionate Mometasone furoate Azatadine (dimaleate) Ticagrelor WIN 55,212-2 (Mesylate) Empty
e Empty TAK-875 NSC 23766 (trihydrochloride) Rupatadine (Fumarate) Aprepitant Conivaptan (hydrochloride) CGS 21680 (Hydrochloride) MK-571 (sodium salt) Fexofenadine (hydrochloride) JDTic (dihydrochloride) WAY-100635 Maleate Empty
f Empty WAY-100635 (maleate salt) Ciclesonide 2-Cl-IB-MECA UNC0642 Anamorelin Bepotastine (Beslilate) Doxazosin (mesylate) Bosentan AM251 [Leu5]-Enkephalin Empty
g Empty Adomeglivant Dronedarone Tarafenacin (D-tartrate) Olmesartan (medoxomil) Otilonium (bromide) GRA Ex-25 Aclidinium (Bromide) JNJ-31020028 lumateperone (Tosylate) MK-0974 Empty
h Empty PF-4136309 Bosentan (hydrate) DADLE AZ3451 JD-5037 Tyr-Gly-Gly-Phe-Met-OH Zafirlukast Netupitant EHT 1864 Anamorelin (hydrochloride) Empty

Plate layout: HY-L006-9

1 2 3 4 5 6 7 8 9 10 11 12
a Empty ZCL278 Orexin 2 Receptor Agonist Macitentan 6H05 (trifluoroacetate) MK-3207 (Hydrochloride) Salmeterol (xinafoate) Montelukast (sodium) Candesartan (Cilexetil) Endomorphin 1 Mosapride (citrate) Empty
b Empty NKP608 Ibutamoren (Mesylate) Elagolix Metoprolol (Succinate) Elagolix sodium Capromorelin (Tartrate) Dihydroergotamine (mesylate) Norbinaltorphimine dihydrochloride PD 123319 (ditrifluoroacetate) Batefenterol Empty
c Empty Neuromedin N TRAP-6 Bromocriptine (mesylate) (±)-Bisoprolol (hemifumarate) Plerixafor (octahydrochloride) Mebhydrolin (napadisylate) Diquafosol (tetrasodium) Gallamine Triethiodide AMD 3465 (hexahydrobromide) Angiotensin (1-7) Empty
d Empty LCZ696 Carbetocin Empty Empty Empty Empty Empty Empty Empty Empty Empty
e Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
f Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
g Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
h Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty

Inquiry Online

Your information is safe with us. * Required Fields.

Product name



Applicant name *


Email address *

Phone number *


Organization name *

Country or Region *


Requested quantity *


Bulk Inquiry

Inquiry Information

Product Name:
GPCR/G Protein Compound Library
Cat. No.:

Request SDF File

Please enter your email address. We will send your requested SDF file to you as soon as possible.