1. Screening Libraries
  2. GPCR/G Protein Compound Library

GPCR/G Protein Compound Library

Cat. No.: HY-L006
Library Contents: XLSX PDF

A unique collection of 655 small molecules targeting G protein coupled receptors used in GPCR screening for various research and drug development projects.

Size (Pre-dissolved DMSO or Solid) Price Stock
30 μL/well (10 mM solution) Get quote In-stock
50 μL/well (10 mM solution) Get quote In-stock
100 μL/well (10 mM solution) Get quote In-stock
250 μL/well (10 mM solution) Get quote In-stock

Please contact us at

[email protected]

Top Publications Citing Use of Products

MCE Screening Library Partners

  • Description

  • Product Details

  • Composition

  • Contents

  • Documentation

& Advantages

•   A unique collection of 655 small molecules targeting G protein coupled receptors used in GPCR screening for various research and drug development projects.

•   Targets such as 5-HT Receptor, Dopamine Receptor, Opioid Receptor, Adrenergic Receptors, Cannabinoid Receptor, mGluR, ETA Receptor, etc.

•   The most successful class of drugable targets in the human genome and remain the most attractive family of targets.

•   All of the small molecules in the GPCR library are well characterized with biological and pharmaceutical activity. Some compounds have been approved by the FDA.

•   A powerful tool for discovering GPCR-based drugs that are the richest signal receptor targets for drug discovery.

•   Structurally diverse, medicinally active, and cell permeable.

•   Rich documentation with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure the highest purity.

•   All compounds are in stock and continuously updated.

Product Details
A collection of 655 GPCR/G Protein related compounds supplied as pre-dissolved DMSO solutions or Solid
96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Blue ice

GPCR/G Protein Compound Library

Source: MedChem Express

Contents of GPCR/G Protein Compound Library

Plate layout: HY-L006-1

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Pimavanserin tartrate Angiotensin II 5-valine Angiotensin II human Bradykinin Oxytocin (acetate) Octreotide (acetate) Desmopressin (Acetate) Terlipressin Gonadorelin (acetate) Leuprolide Acetate Empty
b Empty Alarelin (Acetate) Buserelin (Acetate) Goserelin (acetate) Nicotinamide N-oxide L-Glutamine Eucalyptol Allantoin L-Glutamic acid monosodium salt trans-ACPD Theophylline Empty
c Empty Theobromine Flopropione Carbamoylcholine (chloride) O-Phospho-L-serine Dopamine (hydrochloride) Octopamine (hydrochloride) Scopine (hydrochloride) Methacholine (chloride) Tolazoline (hydrochloride) Bethanechol (chloride) Empty
d Empty TCN238 Xanthotoxol (R)-(-)-Phenylephrine (hydrochloride) Synephrine (hydrochloride) SQ22536 Betahistine (dihydrochloride) (S)-MCPG (RS)-MCPG Harmine Atipamezole Empty
e Empty Serotonin hydrochloride Methoxyphenamine (Hydrochloride) Ferulic acid (sodium) Detomidine (hydrochloride) E4CPG Agmatine (sulfate) RU 24969 MPEP (Hydrochloride) BRL 54443 Melatonin Empty
f Empty VU0364770 Cevimeline (hydrochloride) Arecoline (hydrobromide) Levodropropizine MTEP (hydrochloride) Medetomidine (hydrochloride) Dexmedetomidine (hydrochloride) Tetrahydrozoline (hydrochloride) Acefylline Proxyphylline Empty
g Empty L-(-)-α-Methyldopa (hydrate) Nomifensine CB-7921220 Moxonidine Agomelatine HOKU-81 Osthole Tasimelteon Naphazoline (hydrochloride) 8-OH-DPAT Empty
h Empty Isoprenaline (hydrochloride) Matrine Atipamezole (hydrochloride) Epinastine Oxidopamine (hydrobromide) Clorprenaline hydrochloride Diphylline Irsogladine Eltoprazine (hydrochloride) Xylazine (hydrochloride) Empty

Plate layout: HY-L006-2

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Ramelteon Setiptiline VU0361737 Ethamsylate Tulobuterol hydrochloride Mirtazapine Doxofylline Pemirolast (potassium) Atenolol Clonidine (hydrochloride) Empty
b Empty Sulfisoxazole VUF10460 Oncrasin-1 Piperoxan (hydrochloride) Meptazinol (hydrochloride) Terbutaline (sulfate) Mebhydrolin JNJ-7777120 DREADD agonist 21 Xylometazoline (hydrochloride) Empty
c Empty B-HT 920 Guanfacine (hydrochloride) Reparixin Dexpramipexole (dihydrochloride) Pramipexole (dihydrochloride) Tropicamide Tropisetron Alprenolol (hydrochloride) Zolmitriptan O-desmethyl Mebeverine alcohol (hydrochloride) Empty
d Empty Salbutamol (hemisulfate) Adrafinil L-Hyoscyamine Tizanidine (hydrochloride) WZ811 Guanabenz (Acetate) SKF 38393 (hydrochloride) Diphenhydramine (hydrochloride) Tripelennamine (hydrochloride) MSX-122 Empty
e Empty Dopamine serotonin antagonist-1 Amitraz PHCCC Nuciferine Pizotifen Propranolol (hydrochloride) Fenspiride (Hydrochloride) Ropinirole (hydrochloride) ST034307 AH 6809 Empty
f Empty Piribedil Vortioxetine Metoclopramide Ticlopidine (hydrochloride) Mianserin (hydrochloride) Antazoline (hydrochloride) Desipramine hydrochloride Chlorphenoxamine Lificiguat VU 0357121 Empty
g Empty Anisodamine GSK137647A CASIN Histamine (phosphate) 1A-116 DC260126 Alcaftadine Betaxolol NECA Sotalol (hydrochloride) Empty
h Empty BQCA ML-098 Desloratadine Lodoxamide Cyclobenzaprine (hydrochloride) Olanzapine JWH-133 N-Desmethylclozapine Molindone (hydrochloride) Amezinium (methylsulfate) Empty

Plate layout: HY-L006-3

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Clenbuterol (hydrochloride) ICI 118,551 (hydrochloride) Lu AF21934 Rotigotine Ramosetron (Hydrochloride) Moxisylyte (hydrochloride) Chlorprothixene (1R,2S)-VU0155041 CYM-5541 Pregnenolone Empty
b Empty JNJ-63533054 Metaraminol (tartrate) RS 127445 AVex-73 hydrochloride Diphenylpyraline (hydrochloride) SB-334867 (free base) Ro 67-7476 Imidafenacin Tropisetron (Hydrochloride) Promazine (hydrochloride) Empty
c Empty Asenapine (hydrochloride) Carbazochrome (sodium sulfonate) Ritodrine (hydrochloride) Cyproheptadine (hydrochloride) SCH 23390 (hydrochloride) Dolasetron JNJ16259685 UNBS5162 Clozapine Tranilast (trans-) Empty
d Empty Tranilast Azaperone Loxapine Carteolol (hydrochloride) ABT-239 Alosetron (Hydrochloride) Nizatidine Esmolol (hydrochloride) Pitolisant (hydrochloride) Palonosetron (Hydrochloride) Empty
e Empty L-Epinephrine (Bitartrate) BQU57 Proglumide YL0919 ZM241385 Famotidine Isoxsuprine hydrochloride Trihexyphenidyl (hydrochloride) Topiramate Tetrahydroberberine Empty
f Empty Pumosetrag Hydrochloride Phenoxybenzamine (hydrochloride) CP-809101 (hydrochloride) VU0152100 Levosulpiride Sulpiride (R)-5-Hydroxymethyl Tolterodine Clozapine (N-oxide) Levobetaxolol (hydrochloride) Betaxolol (hydrochloride) Empty
g Empty SCH 58261 Metipranolol hydrochloride Diphenidol (hydrochloride) BD1063 (dhydrochloride) Cortodoxone GW9508 Biperiden (Hydrochloride) OC000459 Acrivastine Granisetron (Hydrochloride) Empty
h Empty N6-Cyclohexyladenosine MDA 19 Ranitidine (hydrochloride) Cyproheptadine (hydrochloride sesquihydrate) Clomipramine (hydrochloride) GR79236 LY 344864 LY 344864 racemate LY334370 CCR2-RA-[R] Empty

Plate layout: HY-L006-4

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Alizapride hydrochloride Rotigotine (Hydrochloride) rac-Rotigotine (Hydrochloride) SB225002 Ro 10-5824 (dihydrochloride) Dimemorfan (phosphate) SB-742457 Metoclopramide (hydrochloride hydrate) Nomifensine (maleate) Seratrodast Empty
b Empty Rotundine Homatropine (Bromide) SB-408124 Pheniramine (Maleate) Cinacalcet Oxybutynin Prednisone Salirasib Glucagon receptor antagonists-2 Glucagon receptor antagonists-3 Empty
c Empty Piperidolate (hydrochloride) BAY 41-2272 Prednisolone Cortisone Calcium-Sensing Receptor Antagonists I Dapiprazole (hydrochloride) Clemizole (hydrochloride) Solifenacin Hydrocortisone TY-52156 Empty
d Empty Labetalol (hydrochloride) Adenosine 5'-monophosphate monohydrate Sinomenine hydrochloride Prucalopride Cinnarizine ADX-47273 Amisulpride Piboserod VU0357017 (hydrochloride) Homatropine (methylbromide) Empty
e Empty Rebamipide Nedocromil N6-(2-Phenylethyl)adenosine Xanomeline (oxalate) Naratriptan (hydrochloride) Acebutolol (hydrochloride) N6-(4-Hydroxybenzyl)adenosine Prasugrel Olopatadine (hydrochloride) Methylprednisolone Empty
f Empty Haloperidol Setiptiline (maleate) Phentolamine (mesylate) Naltrexone (Hydrochloride) Ambrisentan Vortioxetine (hydrobromide) Droperidol SB-222200 Talnetant Misoprostol Empty
g Empty Loratadine PD 117519 Veralipride Quetiapine Fenoterol (hydrobromide) Scopolamine (hydrobromide) Istradefylline Y16 Roxatidine (Acetate Hydrochloride) Azasetron (hydrochloride) Empty
h Empty MK-6892 Ciproxifan (maleate) (RS)-Butyryltimolol Atropine (sulfate monohydrate) Urapidil Doxylamine (succinate) AZD1981 Triflupromazine (hydrochloride) SB-269970 (hydrochloride) Alfuzosin Empty

Plate layout: HY-L006-5

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Diphenmanil (methylsulfate) Regadenoson Flibanserin Chlorpheniramine (maleate) Dexchlorpheniramine (maleate) Rauwolscine (hydrochloride) Yohimbine (Hydrochloride) Rizatriptan (benzoate) CTEP Latrepirdine (dihydrochloride) Empty
b Empty Dexamethasone Betamethasone Naftopidil Deoxycholic acid SB-408124 (Hydrochloride) Cinacalcet (hydrochloride) Oxybutynin (chloride) Triamcinolone SB 242084 Ketanserin Empty
c Empty Mirabegron SCH 527123 TCS-OX2-29 Methscopolamine (bromide) Glycopyrrolate Benzetimide (hydrochloride) Solifenacin (hydrochloride) MK-7622 Scopolamine N-oxide hydrobromide Asenapine (maleate) Empty
d Empty Fenoldopam (mesylate) Setipiprant Formoterol (Fumarate) Cortisone (acetate) Benztropine (mesylate) Bambuterol (hydrochloride) Perphenazine ONO-AE3-208 ALB-127158(a) Ozanimod Empty
e Empty Hydrocortisone (acetate) TBPB Adoprazine GPR120-IN-1 MK-0557 Carvedilol Tozadenant CPPHA Carbinoxamine maleate salt Thioridazine (hydrochloride) Empty
f Empty ML141 Terutroban Trazodone (hydrochloride) Tamsulosin CCG-203971 NPS-2143 PF-04418948 Org 27569 Forskolin Trimipramine (maleate) Empty
g Empty Pergolide (mesylate) SKF-82958 (hydrobromide) Ipratropium (bromide) Decloxizine (dihydrochloride) Noscapine Sumatriptan (succinate) Lasmiditan (hydrochloride) CJ-42794 Asimadoline Deoxycholic acid sodium salt Empty
h Empty Salmeterol Puerarin Ramatroban Desonide Tegaserod (maleate) RS 504393 Azelastine (hydrochloride) Palosuran TC-G-1008 MRE-269 Empty

Plate layout: HY-L006-6

1 2 3 4 5 6 7 8 9 10 11 12
a Empty PF-3274167 Prazosin (hydrochloride) Clopidogrel (hydrogen sulfate) 4-IBP Mepenzolate (Bromide) Ocaperidone ML314 Buspirone (hydrochloride) Methylbenactyzium Bromide Riociguat Empty
b Empty Losartan Pirenzepine (dihydrochloride) Zibotentan RBC8 Trimethobenzamide hydrochloride CID 16020046 Ketotifen (fumarate) Domperidone Fevipiprant Paliperidone Empty
c Empty Iloperidone RS102895 (hydrochloride) BML-190 Mozavaptan Pimavanserin Flavoxate (hydrochloride) Trospium (chloride) AdipoRon Irbesartan ADL-5859 Empty
d Empty ZK756326 (dihydrochloride) Reparixin (L-lysine salt) Mifepristone Budesonide EHop-016 LY310762 Lafutidine (S)-Timolol (Maleate) Latanoprost Brexpiprazole Empty
e Empty Dexamethasone (acetate) Triamcinolone (acetonide) BX471 Cevimeline (hydrochloride hemihydrate) Brompheniramine (maleate) Valsartan Laropiprant Methylnaltrexone (Bromide) BD-1047 (dihydrobromide) LY2119620 Empty
f Empty Scopolamine (butylbromide) Candesartan ONC212 Sertindole SA4503 (dihydrochloride) Vilazodone Deflazacort Quetiapine (fumarate) Nebivolol (hydrochloride) UK 14,304 (tartrate) Empty
g Empty NPS-2143 (hydrochloride) BPTU Loxapine (succinate) Olmesartan MK-3697 Hydroxyzine (dihydrochloride) JTC-801 Aripiprazole Propantheline (bromide) TG6-10-1 Empty
h Empty SB-674042 MBX-2982 Tolvaptan GW842166X K-Ras(G12C) inhibitor 12 Kobe0065 Naltrindole (hydrochloride) ST-836 (hydrochloride) Cabergoline Fluocinolone (Acetonide) Empty

Plate layout: HY-L006-7

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Bay 59-3074 Cenerimod CCG-63808 CCG-1423 AMG 837 (calcium hydrate) Azilsartan AM095 (free acid) GSK1292263 AMD-070 hydrochloride MLE-4901 Empty
b Empty Terazosin (hydrochloride dihydrate) Clemastine (fumarate) Alvimopan (dihydrate) Ponesimod Losartan (potassium) Loxiglumide ONO-7300243 Pimozide Cetirizine (dihydrochloride) Bilastine Empty
c Empty Cariprazine (hydrochloride) Cisapride Sarpogrelate (hydrochloride) Mebeverine (hydrochloride) Loteprednol Etabonate Clobetasol propionate Ziprasidone (hydrochloride monohydrate) SB 242084 (hydrochloride) Almotriptan (malate) Dimenhydrinate Empty
d Empty TCS 1102 Desisobutyryl-ciclesonide Tiotropium (Bromide) MRS 2578 Alverine (citrate) Naftidrofuryl (oxalate) Lixivaptan NAN-190 (hydrobromide) Methylprednisolone succinate Ki16425 Empty
e Empty SRT3190 Dinoprost (tromethamine salt) SR144528 (20S)-Protopanaxatriol Sitaxsentan (sodium) Ebrotidine APD668 Vilazodone (Hydrochloride) AM095 Taprenepag Empty
f Empty Avosentan IT1t (dihydrochloride) GSK682753A Trifluoperazine (dihydrochloride) Solifenacin (Succinate) Pranlukast PF429242 (dihydrochloride) SB-399885 hydrochloride Prednisolone (disodium phosphate) Nicergoline Empty
g Empty Prucalopride (succinate) (±)-SLV319 SB 271046 (Hydrochloride) Pranlukast (hemihydrate) AM966 Grapiprant Vorapaxar Fluocinonide Silodosin NS-304 Empty
h Empty Rimonabant (Hydrochloride) Rolapitant Fluticasone (propionate) Fimasartan Plerixafor Trimebutine (maleate) Preladenant AM630 Betamethasone dipropionate Ivabradine (hydrochloride) Empty

Plate layout: HY-L006-8

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Nefazodone (hydrochloride) BAN ORL 24 Darifenacin (hydrobromide) Clebopride (malate) Indacaterol (maleate) Otenabant Fluphenazine (dihydrochloride) Almorexant Loperamide (hydrochloride) Baohuoside I Empty
b Empty Telmisartan Taranabant Dexamethasone phosphate disodium Siponimod AC-55541 GW-1100 Nastorazepide Eprosartan (mesylate) Beclometasone dipropionate Mometasone furoate Empty
c Empty Azatadine (dimaleate) Ticagrelor WIN 55,212-2 (Mesylate) TAK-875 NSC 23766 (trihydrochloride) Rupatadine (Fumarate) Aprepitant Conivaptan (hydrochloride) CGS 21680 (Hydrochloride) MK-571 (sodium salt) Empty
d Empty Fexofenadine (hydrochloride) JDTic (dihydrochloride) WAY-100635 (maleate salt) Ciclesonide 2-Cl-IB-MECA UNC0642 Anamorelin Bepotastine (Beslilate) Doxazosin (mesylate) Bosentan Empty
e Empty AM251 [Leu5]-Enkephalin Adomeglivant Dronedarone Tarafenacin (D-tartrate) Olmesartan (medoxomil) Otilonium (bromide) GRA Ex-25 Aclidinium (Bromide) JNJ-31020028 Empty
f Empty lumateperone (Tosylate) MK-0974 PF-4136309 Bosentan (hydrate) DADLE [D-Ala2]leucine-enkephalin JD-5037 Tyr-Gly-Gly-Phe-Met-OH Zafirlukast Netupitant Empty
g Empty EHT 1864 Anamorelin (hydrochloride) ZCL278 Orexin 2 Receptor Agonist Macitentan 6H05 (trifluoroacetate) MK-3207 (Hydrochloride) Salmeterol (xinafoate) Montelukast (sodium) Candesartan (Cilexetil) Empty
h Empty Endomorphin 1 Mosapride (citrate) Protease-Activated Receptor-2, amide NKP608 Ibutamoren (Mesylate) Elagolix Metoprolol (Succinate) Elagolix sodium Capromorelin (Tartrate) Protease-Activated Receptor-4 Empty

Plate layout: HY-L006-9

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Dihydroergotamine (mesylate) PD 123319 (ditrifluoroacetate) Batefenterol Neuromedin N TRAP-6 Bromocriptine (mesylate) (±)-Bisoprolol (hemifumarate) Plerixafor (octahydrochloride) Mebhydrolin (napadisylate) Diquafosol (tetrasodium) Empty
b Empty Gallamine Triethiodide AMD 3465 (hexahydrobromide) Angiotensin (1-7) LCZ696 Carbetocin Empty Empty Empty Empty Empty Empty
c Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
d Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
e Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
f Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
g Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
h Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty

Inquiry Online

Your information is safe with us. * Required Fields.

Product name



Applicant name *


Email address *

Phone number *


Organization name *

Country *


Requested quantity *


Bulk Inquiry

Inquiry Information

Product Name:
GPCR/G Protein Compound Library
Cat. No.:

Request SDF File

Please enter your email address. We will send your requested SDF file to you as soon as possible.