1. Screening Libraries
  2. GPCR/G protein Compound Library

GPCR/G protein Compound Library

(572 bioactive Compounds) Cat. No.: HY-L006
Library Contents: XLSX PDF

A unique collection of 572 small inhibitors/regulators for drug development and GPCR research/screening.

Size (Pre-dissolved DMSO or Solid) Price Stock
30 μL/well (10 mM solution) Get quote In-stock
50 μL/well (10 mM solution) Get quote In-stock
100 μL/well (10 mM solution) Get quote In-stock
250 μL/well (10 mM solution) Get quote In-stock

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  • Description

  • Product Details

  • Composition

  • Contents

  • Documentation

& Advantages

•   A unique collection of 572 small molecules targeting G protein coupled receptors used in GPCR screening for various research and drug development projects.

•   All of the small molecules in the GPCR library are well characterized with biological and pharmaceutical activity.

•   A powerful tool for discovering GPCR-based drugs that are the richest signal receptor targets for drug discovery.

•   Targets such as 5-HT Receptor, Dopamine Receptor, Opioid Receptor, Adrenergic Receptors, Cannabinoid Receptor, mGluR, and ETA-receptor etc.

•   Structurally diverse, medicinally active, and cell permeable.

•   Rich documentation with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure the highest purity.

Product Details
A collection of 572 active molecules supplied as pre-dissolved DMSO solutions
96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Blue ice

GPCR/G protein Compound Library

Source: MedChem Express

Contents of GPCR/G protein Compound Library

Plate layout: HY-L006-1

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Fosaprepitant (dimeglumine) Angiotensin II 5-valine Angiotensin II human Bradykinin Oxytocin (acetate) Octreotide (acetate) Histamine Desmopressin (Acetate) Terlipressin Gonadorelin (acetate) Empty
b Empty Leuprolide (Acetate) Buserelin (Acetate) Goserelin (acetate) Nicotinamide N-oxide Abarelix Suramin (sodium salt) L-Glutamine trans-ACPD Theophylline Carbamoylcholine (chloride) Empty
c Empty L-Epinephrine DL-Epinephrine Dopamine (hydrochloride) Octopamine (hydrochloride) Scopine (hydrochloride) Methacholine (chloride) Bethanechol (chloride) Tolazoline (hydrochloride) L-DOPA TCN238 Empty
d Empty Synephrine (hydrochloride) (R)-(-)-Phenylephrine (hydrochloride) SQ22536 Betahistine (dihydrochloride) (S)-MCPG (RS)-MCPG Harmine Atipamezole Methoxyphenamine (Hydrochloride) Ferulic acid (sodium) Empty
e Empty Adrenalone (hydrochloride) Detomidine (hydrochloride) E4CPG RU 24969 MPEP (Hydrochloride) BRL 54443 Lorcaserin (Hydrochloride) Melatonin VU0364770 Arecoline (hydrobromide) Empty
f Empty Levodropropizine MTEP (hydrochloride) Medetomidine (hydrochloride) Dexmedetomidine (hydrochloride) Tetrahydrozoline (hydrochloride) L-(-)-α-Methyldopa (hydrate) CB-7921220 Moxonidine Agomelatine HOKU-81 Empty
g Empty Osthole Pilocarpine (Hydrochloride) Tasimelteon Naphazoline (hydrochloride) Isoprenaline (hydrochloride) Matrine Atipamezole (hydrochloride) Epinastine Oxidopamine (hydrobromide) Cimetidine Empty
h Empty Diphylline Irsogladine Xylazine (hydrochloride) Ramelteon Setiptiline VU0361737 Ethamsylate Mirtazapine Pemirolast (potassium) Atenolol Empty

Plate layout: HY-L006-2

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Clonidine (hydrochloride) Sulfisoxazole VUF10460 Oncrasin-1 Piperoxan (hydrochloride) Meptazinol (hydrochloride) Terbutaline (sulfate) JNJ-7777120 DREADD agonist 21 Xylometazoline (hydrochloride) Empty
b Empty B-HT 920 Guanfacine (hydrochloride) Reparixin Pramipexole (dihydrochloride) Dexpramipexole (dihydrochloride) Tropisetron Tropicamide Alprenolol (hydrochloride) Zolmitriptan Salbutamol (hemisulfate) Empty
c Empty Adrafinil L-Hyoscyamine Tizanidine (hydrochloride) WZ811 Guanabenz (Acetate) SKF 38393 (hydrochloride) Diphenhydramine (hydrochloride) Tripelennamine (hydrochloride) MSX-122 PHCCC Empty
d Empty Pizotifen Propranolol (hydrochloride) Fenspiride (Hydrochloride) Ropinirole (hydrochloride) Oxymetazoline (hydrochloride) Vortioxetine Metoclopramide Ticlopidine (hydrochloride) Mianserin (hydrochloride) Antazoline (hydrochloride) Empty
e Empty Chlorphenoxamine Lificiguat VU 0357121 GSK137647A CASIN Histamine (phosphate) Alcaftadine Betaxolol Sotalol (hydrochloride) BQCA Empty
f Empty ML-098 Desloratadine Lodoxamide Cyclobenzaprine (hydrochloride) Olanzapine JWH-133 Apomorphine (hydrochloride hemihydrate) N-Desmethylclozapine Molindone (hydrochloride) Amezinium (methylsulfate) Empty
g Empty Clenbuterol (hydrochloride) ICI 118,551 (hydrochloride) Lu AF21934 Rotigotine Ramosetron (Hydrochloride) Moxisylyte (hydrochloride) Chlorprothixene (1R,2S)-VU0155041 CYM-5541 Pregnenolone Empty
h Empty JNJ-63533054 Metaraminol (tartrate) RS 127445 Diphenylpyraline (hydrochloride) SB-334867 (free base) Ro 67-7476 Imidafenacin Tropisetron (Hydrochloride) Promethazine (hydrochloride) Promazine (hydrochloride) Empty

Plate layout: HY-L006-3

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Asenapine (hydrochloride) Mequitazine Ritodrine (hydrochloride) Cyproheptadine (hydrochloride) SCH 23390 (hydrochloride) JNJ16259685 UNBS5162 Clozapine Tranilast (trans-) Tranilast Empty
b Empty Azaperone Loxapine Carteolol (hydrochloride) ABT-239 Alosetron (Hydrochloride) Nizatidine Esmolol (hydrochloride) Pitolisant (hydrochloride) Palonosetron (Hydrochloride) L-Epinephrine (Bitartrate) Empty
c Empty BQU57 YL0919 Norepinephrine (bitartrate monohydrate) ZM241385 Famotidine Trihexyphenidyl (hydrochloride) Topiramate Tetrahydroberberine Phenoxybenzamine (hydrochloride) CP-809101 (hydrochloride) Empty
d Empty Naltrexone Sulpiride Levosulpiride VU0152100 (R)-5-Hydroxymethyl Tolterodine Clozapine (N-oxide) Levobetaxolol (hydrochloride) Betaxolol (hydrochloride) SCH 58261 Diphenidol (hydrochloride) Empty
e Empty BD1063 (dhydrochloride) Cortodoxone GW9508 Atropine (sulfate monohydrate) Biperiden (Hydrochloride) OC000459 Acrivastine Granisetron (Hydrochloride) N6-Cyclohexyladenosine MDA 19 Empty
f Empty Ranitidine (hydrochloride) Cyproheptadine (hydrochloride sesquihydrate) Clomipramine (hydrochloride) GR79236 LY 344864 Rotigotine (Hydrochloride) rac-Rotigotine (Hydrochloride) SB225002 Prostaglandin E2 SB-742457 Empty
g Empty Metoclopramide (hydrochloride hydrate) Nomifensine (maleate) Seratrodast Prostaglandin E1 Chlorpromazine (hydrochloride) Homatropine (Bromide) SB-408124 Pheniramine (Maleate) Cinacalcet Oxybutynin Empty
h Empty Prednisone Salirasib Glucagon receptor antagonists-3 Glucagon receptor antagonists-2 BAY 41-2272 Prednisolone Cortisone Calcium-Sensing Receptor Antagonists I Dapiprazole (hydrochloride) Clemizole (hydrochloride) Empty

Plate layout: HY-L006-4

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Hydrocortisone Naloxone (hydrochloride) TY-52156 Labetalol (hydrochloride) Ondansetron (hydrochloride dihydrate) Prucalopride Cinnarizine ADX-47273 Amisulpride Piboserod Empty
b Empty VU0357017 (hydrochloride) Homatropine (methylbromide) Dextromethorphan (hydrobromide hydrate) Rebamipide Nedocromil N6-(2-Phenylethyl)adenosine Xanomeline (oxalate) Epiberberine (chloride) Naratriptan (hydrochloride) Meprednisone Empty
c Empty Acebutolol (hydrochloride) N6-(4-Hydroxybenzyl)adenosine Prasugrel Olopatadine (hydrochloride) Methylprednisolone Haloperidol Setiptiline (maleate) Phentolamine (mesylate) Naltrexone (Hydrochloride) Ambrisentan Empty
d Empty Vortioxetine (hydrobromide) Droperidol SB-222200 Talnetant Misoprostol Loratadine PD 117519 Veralipride Quetiapine Fenoterol (hydrobromide) Empty
e Empty Scopolamine (hydrobromide) Y16 Istradefylline Roxatidine (Acetate Hydrochloride) Azasetron (hydrochloride) Ciproxifan (maleate) MK-6892 Doxylamine (succinate) AZD1981 Triflupromazine (hydrochloride) Empty
f Empty SB-269970 (hydrochloride) Alfuzosin Diphenmanil (methylsulfate) Regadenoson Flibanserin Chlorpheniramine (maleate) Dexchlorpheniramine (maleate) Yohimbine (Hydrochloride) Rizatriptan (benzoate) CTEP Empty
g Empty Dexamethasone Betamethasone Naftopidil SB-408124 (Hydrochloride) Cinacalcet (hydrochloride) Oxybutynin (chloride) Triamcinolone SB 242084 Ketanserin Mirabegron Empty
h Empty SCH 527123 TCS-OX2-29 Methscopolamine (bromide) Glycopyrrolate Benzetimide (hydrochloride) Solifenacin (hydrochloride) Asenapine (maleate) Fenoldopam (mesylate) Setipiprant Formoterol (Fumarate) Empty

Plate layout: HY-L006-5

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Cortisone (acetate) Benztropine (mesylate) Bambuterol (hydrochloride) Perphenazine ONO-AE3-208 Ozanimod Hydrocortisone (acetate) TBPB Adoprazine GPR120-IN-1 Empty
b Empty MK-0557 Carvedilol Tozadenant CPPHA Thioridazine (hydrochloride) ML141 Terutroban Trazodone (hydrochloride) Tamsulosin NPS-2143 Empty
c Empty PF-04418948 Org 27569 Forskolin Trimipramine (maleate) AMD 3465 (hexahydrobromide) SKF-82958 (hydrobromide) Ipratropium (bromide) Decloxizine (dihydrochloride) Noscapine Sumatriptan (succinate) Empty
d Empty Lasmiditan (hydrochloride) CJ-42794 Desonide Tegaserod (maleate) Azelastine (hydrochloride) Palosuran MRE-269 PF-3274167 Prazosin (hydrochloride) Clopidogrel (hydrogen sulfate) Empty
e Empty 4-IBP ML314 Buspirone (hydrochloride) Riociguat Zibotentan RBC8 CID 16020046 Ketotifen (fumarate) Domperidone Fevipiprant Empty
f Empty Iloperidone Paliperidone RS102895 (hydrochloride) BML-190 Mozavaptan Pimavanserin Flavoxate (hydrochloride) Trospium (chloride) AdipoRon Irbesartan Empty
g Empty ADL-5859 Reparixin (L-lysine salt) Mifepristone Budesonide EHop-016 LY310762 Lafutidine (S)-Timolol (Maleate) Latanoprost Brexpiprazole Empty
h Empty Dexamethasone (acetate) Triamcinolone (acetonide) BX471 Cevimeline (hydrochloride hemihydrate) Brompheniramine (maleate) Valsartan Laropiprant Methylnaltrexone (Bromide) BD-1047 (dihydrobromide) Dalasetron (Mesylate hydrate) Empty

Plate layout: HY-L006-6

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Candesartan Sertindole SA4503 (dihydrochloride) Deflazacort Vilazodone Quetiapine (fumarate) Nebivolol (hydrochloride) UK 14,304 (tartrate) NPS-2143 (hydrochloride) Loxapine (succinate) Empty
b Empty Olmesartan MK-3697 Hydroxyzine (dihydrochloride) JTC-801 Aripiprazole TG6-10-1 SB-674042 MBX-2982 Tolvaptan K-Ras(G12C) inhibitor 12 Empty
c Empty Kobe0065 Naltrindole (hydrochloride) ST-836 (hydrochloride) Fluocinolone (Acetonide) Bay 59-3074 Cenerimod CCG-63808 CCG-1423 AMG 837 (calcium hydrate) Azilsartan Empty
d Empty AM095 (free acid) GSK1292263 AMD-070 (hydrochloride) Terazosin (hydrochloride dihydrate) Clemastine (fumarate) Alvimopan (dihydrate) Ponesimod Losartan (potassium) ONO-7300243 Cetirizine (dihydrochloride) Empty
e Empty Bilastine Cariprazine (hydrochloride) Cisapride Sarpogrelate (hydrochloride) Mebeverine (hydrochloride) Loteprednol Etabonate Clobetasol propionate Ziprasidone (hydrochloride monohydrate) Almotriptan (malate) Dimenhydrinate Empty
f Empty TCS 1102 Tiotropium (Bromide) MRS 2578 MK-2894 Naftidrofuryl (oxalate) Alverine (citrate) NAN-190 (hydrobromide) Ki16425 SRT3190 Dinoprost (tromethamine salt) Empty
g Empty (20S)-Protopanaxatriol Sitaxsentan (sodium) Ebrotidine APD668 Vilazodone (Hydrochloride) AM095 Taprenepag Avosentan IT1t (dihydrochloride) GSK682753A Empty
h Empty Trifluoperazine (dihydrochloride) Solifenacin (Succinate) PF429242 (dihydrochloride) Prucalopride (succinate) (±)-SLV319 SB 271046 (Hydrochloride) AM966 Vorapaxar Fluocinonide Silodosin Empty

Plate layout: HY-L006-7

1 2 3 4 5 6 7 8 9 10 11 12
a Empty NS-304 Rimonabant (Hydrochloride) Rolapitant Fluticasone (propionate) Fimasartan Trimebutine (maleate) Preladenant AM630 Ivabradine (hydrochloride) Nefazodone (hydrochloride) Empty
b Empty BAN ORL 24 Darifenacin (hydrobromide) Clebopride (malate) Indacaterol (maleate) Otenabant Fluphenazine (dihydrochloride) Loperamide (hydrochloride) Baohuoside I Telmisartan Taranabant Empty
c Empty Siponimod AC-55541 GW-1100 Eprosartan (mesylate) Beclometasone dipropionate Mometasone furoate Azatadine (dimaleate) Ticagrelor WIN 55,212-2 (Mesylate) TAK-875 Empty
d Empty NSC 23766 (trihydrochloride) Rupatadine (Fumarate) Aprepitant Conivaptan (hydrochloride) CGS 21680 (Hydrochloride) MK-571 (sodium salt) Fexofenadine (hydrochloride) JDTic (dihydrochloride) WAY-100635 (maleate salt) Ciclesonide Empty
e Empty 2-Cl-IB-MECA Ketanserin (tartrate) UNC0642 Anamorelin Bepotastine (Beslilate) Doxazosin (mesylate) Almorexant (hydrochloride) Bosentan AM251 Adomeglivant Empty
f Empty Dronedarone Tarafenacin (D-tartrate) Olmesartan (medoxomil) Otilonium (bromide) GRA Ex-25 Aclidinium (Bromide) lumateperone (Tosylate) MK-0974 PF-4136309 Bosentan (hydrate) Empty
g Empty [D-Ala2]leucine-enkephalin JD-5037 Tyr-Gly-Gly-Phe-Met-OH Zafirlukast EHT 1864 Anamorelin (hydrochloride) ZCL278 Orexin 2 Receptor Agonist Macitentan 6H05 (trifluoroacetate) Empty
h Empty MK-3207 (Hydrochloride) Salmeterol (xinafoate) Montelukast (sodium) Candesartan (Cilexetil) Mosapride (citrate) NKP608 Ibutamoren (Mesylate) Metoprolol (Succinate) Capromorelin (Tartrate) PD 123319 (ditrifluoroacetate) Empty

Plate layout: HY-L006-8

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Batefenterol Neuromedin N TRAP-6 Bromocriptine (mesylate) (±)-Bisoprolol (hemifumarate) Plerixafor (octahydrochloride) Mebhydrolin (napadisylate) Diquafosol (tetrasodium) Gallamine Triethiodide Angiotensin (1-7) Empty
b Empty LCZ696 Carbetocin Empty Empty Empty Empty Empty Empty Empty Empty Empty
c Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
d Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
e Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
f Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
g Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
h Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
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