1. Screening Libraries
  2. GPCR/G Protein Compound Library

GPCR/G Protein Compound Library

Cat. No.: HY-L006
Library Contents: XLSX PDF

A unique collection of 715 small molecules targeting G protein coupled receptors used in GPCR screening for various research and drug development projects.

GPCR/G Protein Compound Library
Size (Pre-dissolved DMSO or Solid) Price Stock
30 μL/well (10 mM solution) Get quote In-stock
50 μL/well (10 mM solution) Get quote In-stock
100 μL/well (10 mM solution) Get quote In-stock
250 μL/well (10 mM solution) Get quote In-stock

Please contact us at

[email protected]

Top Publications Citing Use of Products
  • Description

  • Product Details

  • Composition

  • Contents

  • Documentation

& Advantages

•   A unique collection of 715 small molecules targeting G protein coupled receptors used in GPCR screening for various research and drug development projects.

•   Targets such as 5-HT Receptor, Dopamine Receptor, Opioid Receptor, Adrenergic Receptors, Cannabinoid Receptor, mGluR, ETA Receptor, etc.

•   The most successful class of drugable targets in the human genome and remain the most attractive family of targets.

•   All of the small molecules in the GPCR library are well characterized with biological and pharmaceutical activity. Some compounds have been approved by the FDA.

•   A powerful tool for discovering GPCR-based drugs that are the richest signal receptor targets for drug discovery.

•   Structurally diverse, medicinally active, and cell permeable.

•   Rich documentation with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure the highest purity.

•   All compounds are in stock and continuously updated.

Product Details
A collection of 715 GPCR/G Protein related compounds supplied as pre-dissolved DMSO solutions or Solid
96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Blue ice

GPCR/G Protein Compound Library

Source: MedChem Express

Contents of GPCR/G Protein Compound Library

Plate layout: HY-L006-1

1 2 3 4 5 6 7 8 9 10 11 12
a Empty PD 117519 NPS-2143 Taranabant 4-IBP DREADD agonist 21 Lu AF21934 (RS)-MCPG SQ22536 Ro 67-7476 (S)-MCPG Empty
b Empty JNJ16259685 PHCCC TCS-OX2-29 Plerixafor Bay 59-3074 Aprepitant Flopropione VU0364770 Ticagrelor PSB-12379 Empty
c Empty YL0919 Piperoxan (hydrochloride) Zibotentan ONO-7300243 ZK756326 (dihydrochloride) AR-M 1000390 (hydrochloride) Ocaperidone SB-224289 hydrochloride Naltrindole (hydrochloride) Vorapaxar Empty
d Empty GSK682753A Silodosin Agmatine (sulfate) ST034307 Phenylbiguanide RS 17053 hydrochloride Ro 10-5824 (dihydrochloride) Nicotinamide N-oxide Vanilpyruvic acid CYM-5541 Empty
e Empty VUF10460 IT1t (dihydrochloride) GPR120-IN-1 NPS-2143 (hydrochloride) Veralipride BQCA CB-7921220 AVex-73 hydrochloride DC260126 Prostaglandin E2 Empty
f Empty Navarixin AZD4635 (RS)-Butyryltimolol PD 123319 (ditrifluoroacetate) TC-G-1008 MK-3207 (Hydrochloride) E7046 SB-399885 hydrochloride LY334370 5'-N-Ethylcarboxamidoadenosine Empty
g Empty MRS-1706 SB297006 WAY-100635 Maleate BETP 1A-116 MK-2894 MK-2894 (sodium salt) AH 6809 SKF-82958 (hydrobromide) Fasiglifam Empty
h Empty JDTic (dihydrochloride) Ketanserin Ketanserin (tartrate) Sarpogrelate (hydrochloride) Ponesimod Palosuran MK-6892 Pridopidine Asimadoline VU 0365114 Empty

Plate layout: HY-L006-2

1 2 3 4 5 6 7 8 9 10 11 12
a Empty CGP71683 hydrochloride Methiothepin mesylate CJ-42794 Almorexant Almorexant (hydrochloride) Teijin compound 1 (Z)-Thiothixene CCG-203971 Otenabant Istradefylline Empty
b Empty Preladenant RO1138452 SB-334867 (free base) SB-674042 TCS 1102 Tozadenant (+)-PD 128907 hydrochloride Fingolimod Asenapine (maleate) Sitaxsentan (sodium) Empty
c Empty ONC212 ALB-127158(a) LP-211 Desisobutyryl-ciclesonide 8-OH-DPAT Chlorcyclizine (hydrochloride) N-Acetylhistamine VU0467154 AZ3451 LIT-927 Empty
d Empty MBQ-167 H4 Receptor antagonist 1 H-Val-Pro-Pro-OH (TFA) Fingolimod (hydrochloride) GSK1292263 BX471 VU 0238429 JNJ-5207852 ABT-239 Pitolisant (hydrochloride) Empty
e Empty Ozanimod MK-3697 Siponimod Namodenoson BAY 41-2272 Atipamezole (hydrochloride) Atipamezole Angiotensin (1-7) 6H05 (trifluoroacetate) SKF 38393 (hydrochloride) Empty
f Empty Terlipressin Gonadorelin (acetate) Y16 Prucalopride (succinate) Bromocriptine (mesylate) Piribedil Rauwolscine (hydrochloride) Trimethobenzamide hydrochloride ML141 EHop-016 Empty
g Empty RBC8 CASIN BQU57 Dinoprost (tromethamine salt) Batefenterol Pimozide MK-0354 SRT3190 ADL-5859 ADX-47273 Empty
h Empty (R)-ADX-47273 MRS 2578 WAY-100635 (maleate salt) CGS 21680 (Hydrochloride) Biperiden (Hydrochloride) MTEP (hydrochloride) Ambrisentan AM211 BRL 54443 BAN ORL 24 Empty

Plate layout: HY-L006-3

1 2 3 4 5 6 7 8 9 10 11 12
a Empty PF-4136309 Ki16425 Org 27569 WIN 55,212-2 (Mesylate) Montelukast (sodium) VU0152100 TAK-779 SB 242084 SB 242084 (hydrochloride) Xanomeline (oxalate) Empty
b Empty SR144528 PF429242 (dihydrochloride) Nedocromil CID-1067700 JNJ-7777120 Cutamesine dihydrochloride Rupatadine (Fumarate) LY310762 Abarelix Betamethasone Empty
c Empty Betamethasone dipropionate Beclometasone dipropionate Budesonide Clobetasol propionate Deflazacort Leuprolide Acetate Goserelin (acetate) Mifepristone Mometasone furoate MSX-122 Empty
d Empty Norepinephrine (bitartrate monohydrate) Noscapine Pergolide (mesylate) LY 344864 LY 344864 racemate IPSU BPTU Angiotensin II human ICI 118,551 (hydrochloride) Telmisartan Empty
e Empty ZCL278 AMG 837 (calcium hydrate) UNC0642 CCG-1423 CP 376395 Rimonabant (Hydrochloride) Aclidinium (Bromide) Prucalopride Tegaserod (maleate) GW842166X Empty
f Empty Macitentan Lixivaptan TGR5 Receptor Agonist Vilazodone (Hydrochloride) Vilazodone Lodoxamide Indacaterol (maleate) Salmeterol SB 271046 (Hydrochloride) Intepirdine Empty
g Empty AC-55541 Elagolix sodium (1R,2S)-VU0155041 VU0361737 TCN238 Pavinetant Bilastine JNJ-31020028 Latrepirdine (dihydrochloride) Haloperidol Empty
h Empty Clozapine Olanzapine Ziprasidone Sertindole Aripiprazole Talnetant Pimavanserin Pimavanserin tartrate TBPB L-Glutamic acid monosodium salt Empty

Plate layout: HY-L006-4

1 2 3 4 5 6 7 8 9 10 11 12
a Empty MPEP (Hydrochloride) CPPHA Dexamethasone Dexamethasone (acetate) Anamorelin Anamorelin (hydrochloride) Rolapitant Salirasib Cariprazine (hydrochloride) Mirabegron Empty
b Empty Riociguat Adoprazine Elagolix (±)-Ibipinabant Tasimelteon Tarafenacin (D-tartrate) Lasmiditan (hydrochloride) Selexipag Taprenepag Azilsartan Empty
c Empty Lificiguat Volinanserin Fuscoside Cligosiban Sinomenine hydrochloride O-Phospho-L-serine Avosentan ST-836 (hydrochloride) Capromorelin (Tartrate) Reparixin Empty
d Empty Reparixin (L-lysine salt) AM966 Ciproxifan (maleate) MBX-2982 Cabergoline Timapiprant SB-269970 (hydrochloride) Forskolin VU 0357121 rac-Rotigotine (Hydrochloride) Empty
e Empty MK-0557 Vortioxetine Vortioxetine (hydrobromide) RS 504393 RS 127445 BML-190 AM251 CTEP INCB 3284 MDA 19 Empty
f Empty PRX-08066 VU 0364439 WZ811 Ebrotidine CP-809101 (hydrochloride) AR 231453 APD668 Piboserod GW9508 MK-7622 Empty
g Empty Kobe0065 SB-222200 NSC 23766 (trihydrochloride) Dobutamine (hydrochloride) Brexpiprazole Eprosartan (mesylate) AdipoRon LY2119620 AZD1981 AMD 3465 (hexahydrobromide) Empty
h Empty AM095 AM095 (free acid) Diphenmanil (methylsulfate) Metipranolol hydrochloride Netupitant UNBS5162 Asenapine (hydrochloride) Setipiprant ML314 LY2828360 Empty

Plate layout: HY-L006-5

1 2 3 4 5 6 7 8 9 10 11 12
a Empty EHT 1864 Oncrasin-1 PSN632408 Eltoprazine (hydrochloride) RU 24969 CID 16020046 SB225002 Fevipiprant Grapiprant TG6-10-1 Empty
b Empty Terutroban BD-1047 (dihydrobromide) Tolvaptan Olmesartan Olmesartan (medoxomil) Dexmedetomidine (hydrochloride) Medetomidine (hydrochloride) Pirenzepine (dihydrochloride) Agomelatine Agomelatine (hydrochloride) Empty
c Empty Alcaftadine Cetirizine (dihydrochloride) Loratadine Pramipexole (dihydrochloride) Dexpramipexole (dihydrochloride) Loteprednol Etabonate Tiotropium (Bromide) Octreotide (acetate) Clozapine (N-oxide) Desmopressin (Acetate) Empty
d Empty (S)-Timolol (Maleate) Metoclopramide Metoclopramide (hydrochloride hydrate) Loxapine Loxapine (succinate) Alarelin (Acetate) Ziprasidone (hydrochloride monohydrate) Iloperidone Guanfacine (hydrochloride) Tripelennamine (hydrochloride) Empty
e Empty Salmeterol (xinafoate) Clopidogrel (hydrogen sulfate) Cortisone Cortisone (acetate) Prednisolone Glycopyrrolate Zafirlukast Carteolol (hydrochloride) Acebutolol (hydrochloride) Atenolol Empty
f Empty Bambuterol (hydrochloride) Metoprolol (Succinate) Candesartan (Cilexetil) Losartan Losartan (potassium) Oxytocin (acetate) Carbetocin Cenerimod Nastorazepide NKP608 Empty
g Empty PRE-084 (hydrochloride) BD1063 (dhydrochloride) Valsartan LCZ696 Mozavaptan Conivaptan (hydrochloride) RS102895 (hydrochloride) Bremelanotide (Acetate) N6-[2-(4-Aminophenyl)ethyl]adenosine JD-5037 Empty
h Empty Tranilast (trans-) K-Ras(G12C) inhibitor 12 N6-(4-Hydroxybenzyl)adenosine N6-Cyclohexyladenosine LY354740 PF-04418948 GR79236 Orexin 2 Receptor Agonist L755507 trans-ACPD Empty

Plate layout: HY-L006-6

1 2 3 4 5 6 7 8 9 10 11 12
a Empty GSK2018682 ZM241385 SCH 58261 SCH 23390 (hydrochloride) JNJ-46778212 Pumosetrag Hydrochloride BIBS 39 lumateperone (Tosylate) TY-52156 VU0357017 (hydrochloride) Empty
b Empty ML-098 NAN-190 (hydrobromide) JNJ-63533054 Adomeglivant MK-571 (sodium salt) GSK137647A PD-168077 maleate Xanthotoxol Clemizole (hydrochloride) Setiptiline Empty
c Empty Setiptiline (maleate) Telcagepant Dopamine serotonin antagonist-1 CCR2-RA-[R] Mavorixafor (hydrochloride) Glucagon receptor antagonists-2 Glucagon receptor antagonists-3 Laropiprant HOKU-81 GRA Ex-25 Empty
d Empty GW-1100 Calcium-Sensing Receptor Antagonists I Ibutamoren (Mesylate) ONO-AE3-208 LY404039 Plerixafor (octahydrochloride) Cevimeline (hydrochloride) Cinacalcet Cinacalcet (hydrochloride) Alosetron (Hydrochloride) Empty
e Empty SB-408124 CCG-63808 Rotigotine (R)-5-Hydroxymethyl Tolterodine SB-408124 (Hydrochloride) Alvimopan (monohydrate) Alvimopan (dihydrate) Cevimeline (hydrochloride hemihydrate) MRE-269 Solifenacin (Succinate) Empty
f Empty Rotigotine (Hydrochloride) B-HT 920 Darifenacin (hydrobromide) Bosentan Bosentan (hydrate) Ramelteon Bepotastine (Beslilate) Dronedarone Paliperidone Palonosetron (Hydrochloride) Empty
g Empty Fenspiride (Hydrochloride) Solifenacin Tolazoline (hydrochloride) Doxylamine (succinate) Decloxizine (dihydrochloride) Perphenazine Fluphenazine (dihydrochloride) Diphenidol (hydrochloride) Methacholine (chloride) Flibanserin Empty
h Empty Alizapride hydrochloride Histamine (phosphate) Dapiprazole (hydrochloride) Zuclopenthixol Regadenoson Adenosine 5'-monophosphate monohydrate Amezinium (methylsulfate) Doxofylline Carvedilol Tropisetron (Hydrochloride) Empty

Plate layout: HY-L006-7

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Quetiapine (fumarate) Azasetron (hydrochloride) Granisetron (Hydrochloride) Tropisetron Melatonin (±)-Bisoprolol (hemifumarate) Doxazosin (mesylate) Pizotifen Topiramate Diphylline Empty
b Empty Pregnenolone Ticlopidine (hydrochloride) Fluticasone (propionate) Ketotifen (fumarate) Lafutidine Ivabradine (hydrochloride) Detomidine (hydrochloride) Azatadine (dimaleate) Mianserin (hydrochloride) Mosapride (citrate) Empty
c Empty Alfuzosin Prazosin (hydrochloride) Tizanidine (hydrochloride) Tranilast Naratriptan (hydrochloride) Irbesartan Nebivolol (hydrochloride) Candesartan Prednisone L-(-)-α-Methyldopa (hydrate) Empty
d Empty Ipratropium (bromide) Desonide Methylprednisolone Oxybutynin Oxybutynin (chloride) Chlorprothixene Ranitidine (hydrochloride) Chlorpheniramine (maleate) Pranlukast Pranlukast (hemihydrate) Empty
e Empty Clemastine (fumarate) Diphenhydramine (hydrochloride) Roxatidine (Acetate Hydrochloride) Nizatidine Tropicamide Sulfisoxazole Irsogladine Triamcinolone Methscopolamine (bromide) Meclizine (dihydrochloride) Empty
f Empty Mirtazapine Rebamipide Phentolamine (mesylate) Cyproheptadine (hydrochloride) Terazosin (hydrochloride dihydrate) Moxonidine Famotidine Trimebutine (maleate) Betaxolol Betaxolol (hydrochloride) Empty
g Empty Levobetaxolol (hydrochloride) Naftopidil Atropine (sulfate monohydrate) Bethanechol (chloride) Clonidine (hydrochloride) Domperidone Fluocinolone (Acetonide) Gallamine Triethiodide Loperamide (hydrochloride) Olopatadine (hydrochloride) Empty
h Empty Phenoxybenzamine (hydrochloride) Salbutamol (hemisulfate) Sotalol (hydrochloride) Xylazine (hydrochloride) Naphazoline (hydrochloride) L-Epinephrine (Bitartrate) Dopamine (hydrochloride) Clomipramine (hydrochloride) Scopine (hydrochloride) Trospium (chloride) Empty

Plate layout: HY-L006-8

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Azelastine (hydrochloride) (R)-(-)-Phenylephrine (hydrochloride) Xylometazoline (hydrochloride) Trazodone (hydrochloride) Brompheniramine (maleate) Fluocinonide Arecoline (hydrobromide) Carbazochrome (sodium sulfonate) Otilonium (bromide) Alverine (citrate) Empty
b Empty Benztropine (mesylate) Betahistine (dihydrochloride) Octopamine (hydrochloride) Trifluoperazine (dihydrochloride) Pemirolast (potassium) Desloratadine Homatropine (Bromide) Hydroxyzine (dihydrochloride) Flavoxate (hydrochloride) Tetrahydrozoline (hydrochloride) Empty
c Empty Guanabenz (Acetate) Propranolol (hydrochloride) Latanoprost Ramosetron (Hydrochloride) Diquafosol (tetrasodium) Misoprostol Ropinirole (hydrochloride) Ciclesonide Triamcinolone (acetonide) Epinastine Empty
d Empty Prednisolone (disodium phosphate) Brimonidine Brimonidine (tartrate) Imidafenacin Dihydroergotamine (mesylate) Ebastine Nicergoline Fenoldopam (mesylate) Cyclobenzaprine (hydrochloride) Ramatroban Empty
e Empty Dolasetron Dolasetron (Mesylate hydrate) Seratrodast Fimasartan Fexofenadine (hydrochloride) Terbutaline (sulfate) Theophylline Triflupromazine (hydrochloride) Piperidolate (hydrochloride) Piperidolate Empty
f Empty Thioridazine (hydrochloride) Diphenylpyraline (hydrochloride) Pheniramine (Maleate) Pindolol Molindone (hydrochloride) Sulpiride Metergoline Levosulpiride Dexchlorpheniramine (maleate) Antazoline (hydrochloride) Empty
g Empty Ethamsylate Oxidopamine (hydrobromide) Cinnarizine Naftidrofuryl (oxalate) Labetalol (hydrochloride) Nomifensine Nomifensine (maleate) Amitraz Buspirone (hydrochloride) Flunisolide Empty
h Empty Penbutolol (sulfate) Cyproheptadine (hydrochloride sesquihydrate) Hydrocortisone (acetate) Propantheline (bromide) Histamine Atropine Carbamoylcholine (chloride) Trimipramine (maleate) Dimenhydrinate Promazine (hydrochloride) Empty

Plate layout: HY-L006-9

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Droperidol Trihexyphenidyl (hydrochloride) Mepyramine maleate Mebhydrolin (napadisylate) Mebhydrolin Chloropyramine hydrochloride Proglumide Clorprenaline hydrochloride Homatropine (methylbromide) Esmolol (hydrochloride) Empty
b Empty Nefazodone (hydrochloride) Moxisylyte (hydrochloride) Azaperone Serotonin hydrochloride Acefylline Acrivastine Alprenolol Alprenolol (hydrochloride) Benzetimide (hydrochloride) Carbinoxamine maleate salt Empty
c Empty Chlorphenoxamine Clebopride (malate) Clenbuterol (hydrochloride) Corticosterone Proxyphylline Dexamethasone phosphate disodium Levodropropizine Methylprednisolone succinate Methylbenactyzium Bromide Scopolamine N-oxide hydrobromide Empty
d Empty Loxiglumide Mequitazine Dimemorfan (phosphate) N-Desmethylclozapine Solifenacin (hydrochloride) Baohuoside I Ginsenoside Rb2 Nuciferine Osthole Ferulic acid (sodium) Empty
e Empty Eucalyptol Rotundine Yohimbine (Hydrochloride) Synephrine (hydrochloride) Theobromine Puerarin Matrine Epiberberine (chloride) Scopolamine (hydrobromide) Tetrahydropalmatine Empty
f Empty Scopolamine (butylbromide) L-Glutamine L-Hyoscyamine Allantoin Hydrocortisone Anisodamine Deoxycholic acid Deoxycholic acid sodium salt Ginsenoside Ro Harmine Empty
g Empty Isocorynoxeine (20S)-Protopanaxatriol Tetrahydroberberine β-Caryophyllene p-Hydroxycinnamic acid Tyr-Gly-Gly-Phe-Met-OH TRAP-6 Neuromedin N Angiotensin II 5-valine Endomorphin 1 Empty
h Empty [Leu5]-Enkephalin [Des-Arg9]-Bradykinin (acetate) JMV 2959 hydrochloride Olivetol Tulobuterol hydrochloride Empty Empty Empty Empty Empty Empty

Inquiry Online

Your information is safe with us. * Required Fields.

Product name



Applicant name *


Email address *

Phone number *


Organization name *

Country or Region *


Requested quantity *


Bulk Inquiry

Inquiry Information

Product Name:
GPCR/G Protein Compound Library
Cat. No.:

Request SDF File

Please enter your email address. We will send your requested SDF file to you as soon as possible.