Signaling Pathway

ULK

ULK

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ULK Inhibitors & Modulators (2)

Product Name Catalog No. Brief Description
MRT68921 hydrochloride

HY-100006A

MRT68921 hydrochloride is the most potent inhibitor of both ULK1 and ULK2, with greater than a 15-fold reduction in the IC50 for ULK1 (2.9 nM) and greater than a 30-fold reduction for ULK2 (1.1 nM).

SBI-0206965

HY-16966

SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for the highly related kinase ULK2 .