2607143-50-8
2607143-50-8
Chemical Structure
XST-14
- CAS No.: 2607143-50-8
- Formula:C16H21NO4
- Molecular Weight:291.34
IUPAC Name: methyl 4,6-diisopropoxy-1H-indole-2-carboxylate
InChIKey: ZNFMBFABCSHXPM-UHFFFAOYSA-N
SMILES: O=C(OC)C1=CC2=C(OC(C)C)C=C(OC(C)C)C=C2N1
Biological Activity: XST-14 is a potent, competitive and highly selective ULK1 inhibitor with an IC50 of 26.6 nM. XST-14 induces autophagy inhibition by reducing the phosphorylation of the ULK1 downstream substrate. XST-14 induces apoptosis in hepatocellular carcinoma (HCC) cells and has antitumor effects[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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XST-14 | 99.26% | XST-14 is a potent, competitive and highly selective ULK1 inhibitor with an IC50 of 26.6 nM. XST-14 induces autophagy inhibition by reducing the phosphorylation of the ULK1 downstream substrate. XST-14 induces apoptosis in hepatocellular carcinoma (HCC) cells and has antitumor effects. | ||||||||||||||||||||
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References
Keywords
