FGFR-1
FGFR1, also known as Fms-related tyrosine kinase 2 (FLT2), is a receptor tyrosine kinase that binds multiple FGF ligands, notably FGF1, FGF2 and FGF8, in complexes with heparan sulfate proteoglycans or Klotho co-receptors. Alternative splicing of the third immunoglobulin-like domain generates IIIb and IIIc variants that dictate ligand specificity, and FGFR1 signals mainly through the mesenchymal IIIc form. Ligand-induced dimerization activates downstream RAS-MAPK, PI3K-Akt and PLCγ pathways controlling proliferation, migration and development. FGFR1 is essential for mesoderm, limb and brain patterning; loss-of-function mutations cause Kallmann syndrome while gain-of-function changes underlie Pfeiffer syndrome. FGFR1 amplification occurs in breast and squamous lung cancers, making it an oncology target.
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FGFR-1 Recombinant Proteins (20)
FGFR-1 alpha (IIIc) Protein, Human (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P77660
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 alpha (IIIc) Protein, Human (HEK293, His-Avi)
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Cat. No.: HY-P77659
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 beta (IIIc) Protein, Human (HEK293, His-Avi)
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Cat. No.: HY-P77654
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 Protein, Mouse (HEK293, Fc)
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Cat. No.: HY-P75767
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 beta Protein, Human (HEK293, His-Fc)
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Cat. No.: HY-P73054
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 beta Protein, Human (HEK293, His)
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Cat. No.: HY-P73055
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 Protein, Mouse (HEK293, His)
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Cat. No.: HY-P75768
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 beta (IIIb) Protein, Human (HEK293, Fc)
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Cat. No.: HY-P75765
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 beta (IIIb) Protein, Human (HEK293, His)
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Cat. No.: HY-P75766
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 alpha (IIIb) Protein, Human (HEK293, His)
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Cat. No.: HY-P75764
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 Protein, Rhesus Macaque (HEK293, His)
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Cat. No.: HY-P75770
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 beta Protein, Human (HEK293, hFc)
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Cat. No.: HY-P700436
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein Kinase; Proto-Oncogene C-Fgr; Fms-Like Tyrosine Kinase 2; N-SAM; FGFR1/PLAG1 Fusion; CD331; Pfeiffer Syndrome; Fms-Related Tyrosine Kinase 2; CD331 Antigen; BFGF-R-1; HRTFDS; FGFR-1; N-Sam; FGFBR; ECCL; FLT-2; HH2; HBGFR; OGD; H2; Fibroblast Growth Factor Receptor 1; H4
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FGFR-1 beta (IIIc) Protein, Human (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P700720
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 Protein, Rhesus Macaque (HEK293, Fc)
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Cat. No.: HY-P75769
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 alpha Protein, Human (HEK293, C-His)
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Cat. No.: HY-P700635
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 alpha (IIIb) Protein, Human (HEK293, Fc)
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Cat. No.: HY-P75763
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 beta (IIIc) Protein, Human (355a.a, HEK293, His)
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Cat. No.: HY-P705472
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Fibroblast growth factor receptor 1; EC:2.7.10.1; FGFR-1; Basic fibroblast growth factor receptor 1; BFGFR; bFGF-R-1; Fms-like tyrosine kinase 2; FLT-2; N-sam; CD331; FGFR1; BFGFR, CEK, FGFBR; FLG; FLT2; HBGFR
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FGFR-1 alpha Protein, Human (N546K, sf9, His-GST)
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Cat. No.: HY-P705822
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 alpha Protein, Human (Active, Biotinylated, sf9, Avi)
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Cat. No.: HY-P705823
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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FGFR-1 alpha Protein, Human (Active, V561M, sf9, His-GST)
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Cat. No.: HY-P705824
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FGFR1; H3; Prev. FLT2; H5; Prev. KAL2; Heparin-Binding Growth Factor Receptor; BFGFR; Fibroblast Growth Factor Receptor; CEK; Receptor Protein-Tyrosine Kinase; FLG; FMS-Like Tyrosine Kinase 2; Basic Fibroblast Growth Factor Receptor 1; Hydroxyaryl-Protein
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
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Capetin (28-54), human
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- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
