Tumorigenesis-Related Compound Library

83 Cited Publications
Customer Review

Based on 83 publication(s) in Google Scholar

Cancer is a multi-step process which involves initiation, promotion and progression. Chemical carcinogens can alter any of these processes to induce their carcinogenic effects. People are continuously exposed exogenously to varying amounts of chemicals that have been shown to have carcinogenic or mutagenic properties in experimental systems. Exposure can occur exogenously when these agents are present in food, air or water, and also endogenously when they are products of metabolism or pathophysiologic states such as inflammation. The administration of chemical carcinogens is one of the most commonly used methods to induce tumors in several organs in laboratory animals in order to study oncologic diseases of humans. MCE offers a unique collection of 146 chemical carcinogens which have been identified with carcinogenic activity either in humans or in animal models. MCE Tumorigenesis-Related Compound Library is a powerful tool for studying oncologic diseases of humans. Standard opration based on safety data sheet will not cause harm to the body.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, and 2 mM for compounds with solubility between 2 mM and 10 mM.

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Description & Advantages

•   A unique collection of 146 chemical carcinogens which have been identified with carcinogenic activity either in humans or in animal models.

•   A useful tool for studying oncologic diseases of humans.

•   Detailed compound information with structure, IC50, and brief introduction.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

Product Details

Formulation

A collection of 146 Tumorigenesis-related compounds supplied as pre-dissolved Solutions or Solid.

Solution: 144 compounds supplied in 10 mM solution, 2 compounds supplied in 2 mM solution.

Layout

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates.
This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode.

Storage
-80°C
Shipping
Blue ice or dry ice

Documentation

  • PDF
  • Excel
  • SDF
  • Manual

Composition

Bacterial (32)

Apoptosis (29)

Antibiotic (22)

Autophagy (18)

Parasite (11)

Fungal (9)

Herbicide (7)

NF-κB (6)

PPAR (6)

HIV (4)

CMV (3)

COX (3)

MDM-2/p53 (3)

Caspase (2)

ERK (2)

HSP (2)

HSV (2)

PKC (2)

AMPK (1)

c-Myc (1)

DNA Stain (1)

Exosomes (1)

FXR (1)

JNK (1)

Mitophagy (1)

Mitosis (1)

MMP (1)

Organoid (1)

p38 MAPK (1)

PERK (1)

SOD (1)

Others (3)

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200 mg
USD 120
In-stock
Estimated to ship on August 31 More
500 mg
Get Quote
Consult sales personnel for more information
Bulk Inquiry
500 mg
Get Quote
Consult sales personnel for more information
Bulk Inquiry
Estimated to ship on August 31 More