Signaling Pathway

Myosin

Myosin

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Myosin Inhibitors & Modulators (4)

Product Name Catalog No. Brief Description
(-)-Blebbistatin

HY-13441

(-)-Blebbistatin is a selective inhibitor of myosin II ATPase activity with IC50 of 0.5 - 5 μM.

BTS

HY-16690

BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~ 5 μM) and reversibly blocks the gliding motility.

ML-7 hydrochloride

HY-15417

ML-7 Hcl is a cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM); also inhibt smooth-muscle myosin light chain kinase, protein kinase C (PKC) and cAMP-dependent protein kinase (PKA).

Omecamtiv mecarbil

HY-14233

Omecamtiv mecarbil (CK-1827452) is a selective sarcomere-directed cardiac myosin activator with an EC50 of 0.6 μM.