1. Cytoskeleton
  2. Myosin
  3. BTS

BTS (Synonyms: N-Benzyl-p-toluenesulfonamide; N-Tosylbenzylamine)

Cat. No.: HY-16690 Purity: 99.78%
Handling Instructions

BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~ 5 μM) and reversibly blocks the gliding motility.

For research use only. We do not sell to patients.

BTS Chemical Structure

BTS Chemical Structure

CAS No. : 1576-37-0

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 106 In-stock
Estimated Time of Arrival: December 31
500 mg USD 96 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Description

BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~ 5 μM) and reversibly blocks the gliding motility. IC50 value: 5 uM Target: Ca2+-stimulated myosin S1 ATPase BTS also weakens myosin’s interaction with F-actin. BTS is much less effective in suppressing contraction in rat myocardial or rabbit slow twitch muscle and has no effect on platelet myosin II.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 33.33 mg/mL (127.54 mM)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8264 mL 19.1322 mL 38.2643 mL
5 mM 0.7653 mL 3.8264 mL 7.6529 mL
10 mM 0.3826 mL 1.9132 mL 3.8264 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (9.57 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (9.57 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

261.34

Formula

C₁₄H₁₅NO₂S

CAS No.

1576-37-0

SMILES

O=S(NCC1=CC=CC=C1)(C2=CC=C(C)C=C2)=O

Shipping

Room temperature in continental US; may vary elsewhere

Purity: 99.78%

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
BTS
Cat. No.:
HY-16690
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BTS

Cat. No.: HY-16690