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II

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By Research Areas:	Cancer (425) Cardiovascular Disease (179) Endocrinology (85) Infection (124) Inflammation/Immunology (129) Metabolic Disease (115) Neurological Disease (148)
Click Chemistry:	Azide (2) Alkynes (5)

1116

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

180

Peptides

MCE Kits

Inhibitory Antibodies

146

Natural
Products

215

Recombinant Proteins

Isotope-Labeled Compounds

102

Antibodies

Click Chemistry

Urotensin II-related peptide	Urotensin Receptor	Cardiovascular Disease
Urotensin II-related peptide is a human urotensin II anague. Urotensin II-related peptide has high affinity for the UT receptor .

II399	Others	Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
II399 is a potent, selective NNMT bisubstrate inhibitor containing an unconventional SAM mimic, with a K_i of 5.9 nM. II399 exhibits an explicit pattern of competitive inhibition for NAM. II399 occupies both the substrate and cofactor binding pockets. II399 has the potential for the research of cancers, metabolic, cardiovascular, and neurodegenerative diseases .

II-B08	SHP2	Cancer
II-B08 is a reversible and noncompetitive SHP2 inhibitor (IC₅₀: 5.5 μM, 15.7, 14.3 μM for SHP2, SHP1, PTP1B). II-B08 can be used for cancer research .

Topo II/HDAC-IN-2	Topoisomerase HDAC Apoptosis	Cancer
Topo II/HDAC-IN-2 (8d) exhibits excellent dual inhibitory activities against Topo II and HDAC. Topo II/HDAC-IN-2 (8d) induces apoptosis .

Topo II/HDAC-IN-1	Topoisomerase HDAC Apoptosis	Cancer
Topo II/HDAC-IN-1 (7d) exhibits excellent dual inhibitory activities against Topo II and HDAC. Topo II/HDAC-IN-1 (8d) induces apoptosis .

[Orn8]-Urotensin II (human)	Urotensin Receptor	Cardiovascular Disease
[Orn8]-Urotensin II (human), a peptide analog of urotensin II, is a UT receptor agonist. [Orn8]-Urotensin II (human) increases intracellular calcium levels in HEK293 .

Angiotensin I/II (4-8)	Endogenous Metabolite	Cardiovascular Disease
Angiotensin I/II (4-8), a major metabolite of Angiotensin II, is a C-terminal 4-8 pentapeptide .

Topoisomerase I/II inhibitor 4	Topoisomerase Apoptosis	Cancer
Topoisomerase I/II inhibitor 4 (compound F16) is a potent topoisomerase I (Topo I) and II (Topo II) dual inhibitor. Topoisomerase I/II inhibitor 4 inhibits cell proliferation, invasion and migration and induces apoptosis. Topoisomerase I/II inhibitor 4 can be used for liver cancer research .

Hexokinase II VDAC binding domain peptide Hxk2VBD peptide	Hexokinase	Neurological Disease
Hexokinase II VDAC binding domain peptide (Hxk2VBD peptide) is a cell-permeable hexokinase II VDAC binding domain. Hexokinase II VDAC binding domain peptide inhibits mitochondrial localization of hexokinase 2 (HXK2). Hexokinase II VDAC binding domain peptide inhibits neurotrophic factor-directed axon outgrowth .

Topoisomerase II inhibitor 14	Topoisomerase Apoptosis	Cancer
Topoisomerase II inhibitor 14 (compound 2f) is a potent inhibtor of Topoisomerase II, with anticancer activity. Topoisomerase II inhibitor 14 induces apoptosis, and arrests cell cycle at S phase. Topoisomerase II inhibitor 14 exhibits antioxidant effect and decreases the level of GSH, MDA, and NO .

Topoisomerase II inhibitor 19	Topoisomerase	Cancer
Topoisomerase II inhibitor 19 (compound 5h) is a DNA intercalator and topoisomerase II inhibitor (IC₅₀ value of 0.34 μM). Topoisomerase II inhibitor 19 would induce detectable potent damage in ctDNA .

Topoisomerase II inhibitor 15	Topoisomerase Apoptosis	Cancer
Topoisomerase II inhibitor 15 (compound 2g) is a Topoisomerase II inhibitor. Topoisomerase II inhibitor 15 potently is an apoptotic inducer with greater selectivity against head and neck tumors .

Topoisomerase II inhibitor 17	Topoisomerase Apoptosis	Cancer
Topoisomerase II inhibitor 17 (compound 4c) is an inhibitor of thiazolopyrimidine topoisomerase (Topoisomerase) Top II (IC₅₀: 0.23 μM). Topoisomerase II inhibitor 17 can significantly cause cell cycle disruption and apoptosis .

Topoisomerase II inhibitor 11	Topoisomerase Apoptosis	Cancer
Topoisomerase II inhibitor 11 (compound 3d) is a potent Topoisomerase II inhibitor, with an IC₅₀ of 2.89 μM. Topoisomerase II inhibitor 11 shows 92.46% inhibition on renal cancer cell line A498 with an IC₅₀ of 3.5 μM. Topoisomerase II inhibitor 11 causes cell cycle arrest at the G2/M phase leading to cell proliferation inhibition and pro-apoptotic activity .

Topoisomerase II inhibitor 6	Topoisomerase	Cancer
Topoisomerase II inhibitor 6 (Compound 5), a tryptanthrin derivative, is a potent and selective inhibitor of topoisomerase II. Topoisomerase II inhibitor 6 exhibits antiproliferative activity on different tumor cell lines. Topoisomerase II inhibitor 6 blocks the cell cycle of CCRF-CEM in the G2 phase and induces DNA DSB. Topoisomerase II inhibitor 6 has the potential for the research of cancer diseases .

Topoisomerase II inhibitor 16	Topoisomerase Parasite	Infection
Topoisomerase II inhibitor 16 (compound CT3) is a selective, orally active, brain-penetrant and irreversible trypanosomal topoisomerase II inhibitor by stabilizing double-stranded DNA:enzyme cleavage complexes. Topoisomerase II inhibitor 16 has the potential for Chagas disease research .

Angiotensin amide (Asn1,Val5)-Angiotensin II	Angiotensin Receptor	Inflammation/Immunology
Angiotensin amide ((Asn1,Val5)-Angiotensin II) is a potent vasoconstrictor. Angiotensin amide is a derivative of angiotensin II. Angiotensin amide can be used as a cardiac activator .

Adipokinetic hormone II (Locusta migratoria) Lom-AKH-II	Endogenous Metabolite	Metabolic Disease
Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) .

Topoisomerase I/II inhibitor 2	Topoisomerase	Cancer
Topoisomerase I/II inhibitor 2 (compound 1a) is a potent Topoisomerase inhibitor (IC₅₀= 9.82 μM on Huh7 cells and 6.83 μM on LM9 cells). Topoisomerase I/II inhibitor 2 has dual inhibition on DNA topoisomerase I/II, also can obviously reduce the growth of xenograft tumor in mice model. Topoisomerase I/II inhibitor 2 has the potential value in researching liver cancer .

Angiotensin II human 90+ Cited Publications Angiotensin II; Ang II; DRVYIHPF	Angiotensin Receptor Apoptosis	Cardiovascular Disease Endocrinology Cancer
Angiotensin II (Angiotensin II) is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .

Angiotensin II human acetate 90+ Cited Publications Angiotensin II acetate; Ang II acetate; DRVYIHPF acetate	Angiotensin Receptor Apoptosis	Cardiovascular Disease Endocrinology Cancer
Angiotensin II human (Angiotensin II) acetate is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human acetate plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human acetate stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human acetate induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human acetate also induces apoptosis. Angiotensin II human acetate induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .

Endoglycoceramidase II (EGCase II)	Endogenous Metabolite	Metabolic Disease
Endoglycoceramidase II (EGCase II) is an endo-β-glucosidase releasing the complete glycan from ceramide in glycosphingolipids. Endoglycoceramidase II Catalyzes the hydrolysis of the β-glycosidic linkage between oligosaccharides and ceramides in various glycosphingolipids .

Deoxyribonuclease II DNase II	Endonuclease	Others
Deoxyribonuclease II (DNase II) is an endonuclease that hydrolyzes the phosphodiester bonds of deoxyribonucleotides in native and denatured DNA, producing 3' phosphate and 5'-hydroxyl termini. Deoxyribonuclease II works best at acidic pH and is commonly used in biochemical research .

Angiotensin II human TFA 90+ Cited Publications Angiotensin II TFA; Ang II TFA; DRVYIHPF TFA	Angiotensin Receptor Apoptosis	Cardiovascular Disease Endocrinology Cancer
Angiotensin II human (Angiotensin II) TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human TFA plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human TFA stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human TFA induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human TFA also induces apoptosis. Angiotensin II human TFA induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .

Lacto-N-fucopentaose II LNFP II	Endogenous Metabolite	Metabolic Disease
Lacto-N-fucopentaose II (LNFP II) is a sialyl-Lewis, hapten of human Lewis bloodgroup determinant. Lacto-N-fucopentaose II monosialo-ganglioside/glycolipid and sialyl derivative, CA 19-9, is a molecular tumour markers (TM) for biliopancreatic malignancy .

Urechistachykinin II Uru-TK II	Bacterial	Infection
Urechistachykinin II (Uru-TK II), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect .

Praeroside II	Others	Others
Praeroside II is an angular-type pyranocoumarm glycoside. Praeroside II can be isolated from the n-butanol-extracts of P. praeruptorum Dunn. Praeroside II can be used for pharmacological study .

Targocil-II	Bacterial Antibiotic	Infection
Targocil-II (Compound 2) is an ABC transporter inhibitor with a IC₅₀ value of 137 nM. Targocil-II prevents ATP hydrolysis by binding to allosteric sites of the TM domain. Targocil-II has (antibacterial) activity .

Bisindolylmaleimide II Bis II	PKC	Metabolic Disease Cancer
Bisindolylmaleimide II is a general inhibitor of all PKC subtypes .

Iron(II) fumarate Ferrous fumarate	Others	Metabolic Disease Cancer
Iron(II) fumarate (Ferrous fumarate) is the iron(II) salt of fumaric acid. Iron(II) fumarate is an orally active dietary supplement and has the potential for iron deficiency anemia treatment .

Aristololactam II	Others	Others
Aristololactam II, a metabolite of Aristolochic acid II (AAII), is an excretion product found in the urine, which is considered to be detoxification metabolite of AAII .

Aah II	Sodium Channel	Inflammation/Immunology
Aah II is a sodium channel modulator. Aah II is a toxin that can be isolated from the venom of scorpion Androctonus australis .

Angiotensin II antipeptide	Angiotensin Receptor	Cardiovascular Disease
Angiotensin II antipeptide, a peptide, is an inverse agonist of AR1 receptor. Angiotensin II antipeptide is encoded by mRNA, complementary to that encoding Angiotensin II (HY-13948) itself .

Crocin II	NO Synthase COX Endogenous Metabolite	Neurological Disease Inflammation/Immunology Cancer
Crocin II is isolated from the fruit of Gardenia jasminoides with antioxidant, anticancer, and antidepressant activity. Crocin II inhibits NO production with an IC₅₀ value of 31.1 μM. Crocin II suppresses the expressions of protein and m-RNA of iNOS and COX-2 .

Isotanshinone II	Others	Neurological Disease
Isotanshinone II is a natural product that can be isolated from Salvia glutinos. Isotanshinone II can be used to study Alzheimer's disease .

Lacto-N-difucohexaose II LNDFH II ; Lacto-N-fucohexaose	Others	Others
Lacto-N-difucohexaose II (LNDFH II) is one of the oligosaccharides in human milk, it is important for infant health .

SRE-II	DNA/RNA Synthesis Apoptosis	Cancer
SRE-II, an amide derivative, is an activatable photosensitizer for photodynamic cancer research with decreased fluorescence and photosensitizing capabilities. SRE-II can be further converted into the active photosensitizer SDU Red via carboxylesterase-catalyzed amide bond cleavage. SRE-II induces DNA damage and cell apoptosis in the presence of light. SRE-II can act as a promising theranostic agent for triple-negative breast cancer .

Flaccidoside II	Apoptosis	Inflammation/Immunology
Flaccidoside II inhibits proliferation and induces apoptosis in Malignant peripheral nerve sheath tumors (MPNSTs) cell lines. Flaccidoside II ameliorates collagen-induced arthritis in mice. Flaccidoside II is an active triterpenoid saponin constituent from Anemone flaccida rhizome .

Campneoside II	Others	Others
Campneoside II is a compound isolated from Paulownia tomentosa var. tomentosa wood. Campneoside II exhibits excellent anti-complement activity .

BDS-II	Sodium Channel	Neurological Disease
BDS-II is a peptide toxin, and is composed of 43 amino acids. BDS-II is a selective Kv3.4 channel inhibitor .

Cu(II)-Elesclomol	Cuproptosis Apoptosis Topoisomerase	Cancer
Cu(II)-Elesclomol is a Cu ²⁺ complex of Elesclomol (HY-12040). Cu(II)-Elesclomol induces cuproptosis. Cu(II)-Elesclomol also inducesapoptosis, causes a G1 cell cycle block and induces DNA double strand breaks in K562 cells. Cu(II)-Elesclomol also weakly inhibits DNA topoisomerase I. Cu(II)-Elesclomol has anticancer activity .

Skullcapflavone II	Bacterial	Inflammation/Immunology
Skullcapflavone II, a flavonoid derived from Scutellaria baicalensis, has anti-inflammatory, anti-microbial activities. Skullcapflavone II regulates osteoclast differentiation, survival, and function. Skullcapflavone II exerts potent antimicrobial activity against M. aurum and M. bovis BCG .

Ternatumoside II	Others	Inflammation/Immunology
Ternatumoside II is a flavonoid glycoside that can be isolated from R. crenulata. Ternatumoside II can stimulate IFN-γ expression. Ternatumoside II has radical-scavenging activities (IC₅₀s: 260.5 μM and 320.2 μM for DPPH and ABTS) .

Viscidulin II	Others	Inflammation/Immunology
Viscidulin II (FL6) is a flavone. Viscidulin II can be isolated from the root of Scutellaria baicalensis. Viscidulin II significantly suppresses P. acnes-induced IL-8 and IL-1β production in THP-1 cells .

Soyasaponin II	HSV CMV Influenza Virus HIV NOD-like Receptor (NLR) YB-1	Infection Inflammation/Immunology
Soyasaponin II is a saponin with antiviral activity. Soyasaponin II inhibits the replication of HSV-1, HCMV, influenza virus, and HIV-1. Soyasaponin II shows potent inhibition on HSV-1 replication. Soyasaponin II serves as a inhibitor for YB-1 phosphorylation and NLRP3 inflammasome priming and could protect mice against LPS/GalN induced acute liver failure .

ATX-II	Sodium Channel	Inflammation/Immunology
ATX-II is a specific Na ⁺ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II causes delayed inactivation of the Na ⁺II sensitizes skeletal muscle to Halothane (HY-B1010), Caffeine, and Ryanodine (HY-103306). ATX-II also induces pulmonary vein arrhythmogenesis and atrial fibrillation .

Cat. No.	Product Name

HY-L018

TGF-beta/Smad Compound Library

223 compounds

The transforming growth factor beta (TGF-β) signaling pathway is involved in many cellular processes in both the adult organism and the developing embryo including cell growth, cell differentiation, apoptosis, cellular homeostasis and other cellular functions. The TGF-β superfamily comprises TGF-βs, bone morphogenetic proteins (BMPs), activins and related proteins. Signaling begins with the binding of a TGF beta superfamily ligand to a TGF beta type II receptor. The type II receptor is a serine/threonine receptor kinase, which catalyzes the phosphorylation of the Type I receptor. The type I receptor then phosphorylates receptor-regulated SMADs (R-SMADs) which can now bind the coSMAD (e.g. SMAD4). R-SMAD/coSMAD complexes accumulate in the nucleus where they act as transcription factors and participate in the regulation of target gene expression. Deregulation of TGF-β signaling contributes to developmental defects and human diseases, including cancers, some bone diseases, chronic kidney disease, etc.

MCE designs a unique collection of 223 TGF-beta/Smad signaling pathway compounds. TGF-beta/Smad Compound Library acts as a useful tool for TGF-beta/Smad-related drug screening and disease research.

HY-L040

Anti-diabetic Compound Library

740 compounds

Diabetes mellitus, usually called diabetes, is a group of metabolic disorders characterized by a high blood sugar level over a prolonged period of time. The most common types are Type I and Type II. Type I diabetes (T1D), also called juvenile onset diabetes mellitus or insulin-dependent diabetes mellitus, is characterized by destruction of the β-cells of the pancreas and insulin is not produced, whereas type II diabetes (T2D), also called non-insulin-dependent diabetes mellitus, is characterized by a progressive impairment of insulin secretion and relative decreased sensitivity of target tissues to the action of this hormone. Type 2 diabetes accounts for the vast majority of all diabetes mellitus. Diabetes of all types can lead to complications in many parts of the body and can increase the overall risk of dying prematurely. Possible complications include kidney failure, leg amputation, vision loss and nerve damage.

The pathogenesis of diabetes is complicated, and development of the safe and effective drugs against diabetes is full of challenge. Increasing studies have confirmed that the pathogenesis of diabetes is related to various signaling pathways, such as insulin signaling pathway, AMPK pathway, PPAR regulation and chromatin modification pathways. These signaling pathways have thus become the major source of the promising novel drug targets to treat metabolic diseases and diabetes.

MCE Anti-diabetic Compound Library owns a unique collection of 740 compounds, which mainly target SGLT, PPAR, DPP-4, AMPK, Dipeptidyl Peptidase, Glucagon Receptor, etc. This library is a useful tool for discovery anti-diabetes drugs.

HY-L090

Transcription Factor-Targeted Library

1288 compounds

Transcription is the essential first step in the conversion of the genetic information in the DNA into protein and the major point at which gene expression is controlled. Transcription of protein-coding genes is accomplished by the multi-subunit enzyme RNA polymerase II and an ensemble of ancillary proteins, called transcription factors (TFs). Transcription factors play an important role in the long-term regulation of cell growth, differentiation and responses to environmental cues. Deregulated transcription factors contribute to the pathogenesis of a plethora of human diseases, ranging from diabetes, inflammatory disorders and cardiovascular disease to many cancers, and thus these proteins hold great therapeutic potential.

MCE offers a unique collection of 1288 compounds with validated transcription factor targets modulating properties. MCE transcription factor-targeted compound library is an effective tool for researching transcription factors as drug targets as well as modulation of TFs for different therapeutic applications.

Cat. No.	Product Name	Type

HY-112276

Beryllon II	Chromogenic Assays
Beryllon II is a widely used chromogenic reagent that is used to determine many elements, such as Mo, Mg and Co, and also used for the determination of proteins.

HY-W074143

Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride	Fluorescent Dyes/Probes
Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride is an oxygen-sensitive fluorescent indicator widely used as a probe for luminescence detection and quantitative oxygen determination .

HY-D1098

SYBR Green II	Fluorescent Dyes/Probes
SYBR Green II is a fluorescent nucleic acid dye that mainly binds single-stranded nucleotides. SYBR Green II is sensitive to oligonucleotides or larger nucleic acid polymers in a variety of cells and gels. SYBR Green II can be used to study cell structure, membrane integrity or function, and cell cycle distribution. Wavelength 484/515 nm .

HY-D1098A

SYBR Green II (Ionic form)	Fluorescent Dyes/Probes
SYBR Green II (Ionic form) is a fluorescent nucleic acid dye that mainly binds single-stranded nucleotides. SYBR Green II is sensitive to oligonucleotides or larger nucleic acid polymers in a variety of cells and gels. SYBR Green II can be used to study cell structure, membrane integrity or function, and cell cycle distribution. Wavelength 484/515 nm .

HY-D2195

AgAuSe-PEG-NH2 (1000 nm)	Fluorescent Dyes/Probes
AgAuSe-PEG-NH2 (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm that can be used in bioimaging.

HY-D0516

Solvent Blue 35 Sudan Blue II; Oil Blue 35	Chromogenic Assays
Solvent Blue 35 (Sudan Blue II; Oil Blue 35) is a dye used for colouring alcoholic and hydrocarbon based solvents. It is used for staining triglycerides in animal tissues.

HY-135269

Quin II potassium

Dyes

QUIN 2, Tetrapotassium Salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-D2198

AgAuSe-PEG-NH2 (1120 nm)	Fluorescent Dyes/Probes
AgAuSe-PEG-NH2 (1120 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1120 nm that can be used in bioimaging .

HY-133852

FD-1080

Fluorescent Dyes/Probes

FD-1080 is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging .

HY-149835

TTX-P	Fluorescent Dyes/Probes
TTX-P is a fluorescent probe. TTX-P responds in situ to the overexpressed alkaline phosphatase (ALP) in liver, imaging of diabetic liver injury in the near-infrared second-window (NIR-II) region .

HY-D1392

Ag2Te QDs Ag2Te	Quantum Dots
Ag2Te QDs (Ag2Te) is an effective biological probe in the second near-infrared window (NIR-II) that can be used in bioimaging with high tissue penetration depth and high spatiotemporal resolution .

HY-D1895

3,5-DiBr-PAESA	Fluorescent Dyes/Probes
3,5-DiBr-PAESA is a supersensitive chelating agent that can be used for silver (I) determination in water in the case of absence of other interfering ions. 3,5-DiBr-PAESA can also be used for copper (II) determination .

HY-D1393

Pb:Ag2Se QDs Pb:Ag2Se	Quantum Dots
Pb:Ag2Se QDs (Pb:Ag2Se) is an effective biological probe in the second near-infrared window (NIR-II) that can be used in bioimaging with high tissue penetration depth and high spatiotemporal resolution .

HY-D0156

ZnAF-1	Fluorescent Dyes/Probes
ZnAF-1, a fluorescein-based zinc sensor containing the N,N-bis(2-pyridylmethyl)ethylenediamine chelating unit, can be used for Zn2+ detection . ZnAF-1 can bind Zn(II) with a 1 : 1 stoichiometry .

HY-D0256

Direct Black 38 Chlorazol Black E; Ferristatin II disodium; C.I. 30235	Dyes
Direct Black 38 (Chlorazol Black E) is an azo dye. Direct Black 38 induces unscheduled DNA synthesis in liver and micronucleus in bone marrow of rats in vivo .

HY-N6716

Filipin complex 5+ Cited Publications	Fluorescent Dyes/Probes
Filipin complex is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I .

HY-D2194

AgAuSe-COOH (1000 nm)	Fluorescent Dyes/Probes
AgAuSe-COOH (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm. AgAuSe-COOH (1000 nm) has the advantages of narrow band gap, large Stokes shift, and good photostability. AgAuSe-COOH (1000 nm) can bind proteins, antibodies, peptides, PEG, etc., and can be widely used in the field of biological imaging.

HY-D0256A

Direct Black 38 free acid Chlorazol Black E free acid; Ferristatin II; C.I. 30235 free acid	Dyes
Direct Black 38 free acid is a polysulphonated dye. Direct Black 38 free acid promotes degradation of transferrin receptor-1 in vitro and in vivo .

HY-16700G

PNU-159682 (GMP)	Fluorescent Dye
PNU-159682 GMP is a GMP grade PNU-159682 (HY-16700). PNU-159682, a metabolite of the anthracycline Nemorubicin, is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity. PNU-159682 acts as a more potent and tolerated ADC cytotoxin than Doxorubicin for ADC synthesis. PNU-159682 can be used in EDV-nanocell technology to overcome agent resistance.

Cat. No.	Product Name	Type

HY-NP003

Bovine Type II Collagen Collagen, Type II, Immunization Grade	Native Proteins
Type II collagen II is a protein used to treat osteoarthritis. Type II collagen shows significant efficacy in improving the pain and inflammation of collagen induced arthritis in mice .

HY-E70038

Endoglycoceramidase II (EGCase II)	Biochemical Assay Reagents
Endoglycoceramidase II (EGCase II) is an endo-β-glucosidase releasing the complete glycan from ceramide in glycosphingolipids. Endoglycoceramidase II Catalyzes the hydrolysis of the β-glycosidic linkage between oligosaccharides and ceramides in various glycosphingolipids .

HY-136417

Pd(II)TPBP Pd(II) meso-tetraphenyltetrabenzoporphyrin	Biochemical Assay Reagents
Pd(II)TPBP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127794

Quin II

Biochemical Assay Reagents

Quin II is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
HY-P2955

Heparinase II

Biochemical Assay Reagents

Heparinase II is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W002072

Palladium (II) acetate	Biochemical Assay Reagents
Palladium (II) acetate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W033466

Dichloro(benzene)ruthenium(II) dimer Benzeneruthenium(II) chloride dimer	Biochemical Assay Reagents
Benzeneruthenium(II) Chloride Dimer is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127563

Tin(II) stearate

Biochemical Assay Reagents

Tin(II) stearate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W008145

Sodium tetrachloropalladate(II) Sodium tetrachloropalladate(II) trihydrate	Biochemical Assay Reagents
Sodium tetrachloropalladate(II) is an organic compound commonly used as a catalyst and as a raw material for dye production. It can be used to catalyze or promote reactions in certain chemical reactions, and is widely used in the fields of organic synthesis and dye preparation. In addition, the compound is also used for metallization, silver plating and electroplating of circuit boards.

HY-W127815

Pd(II) Mesoporphyrin IX	Biochemical Assay Reagents
Pd(II) Mesoporphyrin IX is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127821

Pt(II) Octaethylporphine ketone	Biochemical Assay Reagents
Pt(II) Octaethylporphine ketone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W112936

Pd(II)TMPyP tetrachloride	Biochemical Assay Reagents
Pd(II)TMPyP tetrachloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W112937

Zn(II)TMPyP tetrachloride	Biochemical Assay Reagents
Zn(II)TMPyP tetrachloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W033312

Dichlorobis(tricyclohexylphosphine)palladium(II)	Biochemical Assay Reagents
Dichlorobis(tricyclohexylphosphine)palladium(II) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W073013

Cobalt(II) TPP

Biochemical Assay Reagents

5,10,15,20-Tetraphenyl-21H,23H-porphine cobalt(II), commonly known as CoTPP or cobalt porphyrin, is a coordination compound. 5,10,15,20-Tetraphenyl-21H,23H-porphine cobalt(II) is widely used in various fields such as catalysis, sensing, and organic electronics because of its unique electronic and optical properties. An efficient catalyst for reactions including oxidation, reduction, and CH bond activation, moreover, it has been used as a fluorescent probe for detecting oxygen content in biological systems and as an active material in organic solar cells.

HY-W127458

Tin(II) palmitate Hexadecanoic acid, tin(2+) salt	Biochemical Assay Reagents
Tin(II) palmitate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-A0104I

HPMC (Type II,Viscosity:100000mPa.s) Hypromellose (Type II,Viscosity:100000mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:100000mPa.s); Celacol HPM 5000 (Type II,Viscosity:100000mPa.s)	Biochemical Assay Reagents
Hydroxypropylmethylcellulose (Type II,Viscosity:100000mPa.s) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-A0104E

HPMC (Type II,Viscosity:100mPa.s) Hypromellose (Type II,Viscosity:100mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:100mPa.s); Celacol HPM 5000 (Type II,Viscosity:100mPa.s)	Biochemical Assay Reagents
Hypromellose (Type II,Viscosity:100mPa.s) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-A0104H

HPMC (Type II,Viscosity:15000mPa.s) Hypromellose (Type II,Viscosity:15000mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:15000mPa.s); Celacol HPM 5000 (Type II,Viscosity:15000mPa.s)	Biochemical Assay Reagents
Hypromellose (Type II,Viscosity:15000mPa.s) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-A0104F

HPMC (Type II,Viscosity:400mPa.s) Hypromellose (Type II,Viscosity:400mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:400mPa.s); Celacol HPM 5000 (Type II,Viscosity:400mPa.s)	Biochemical Assay Reagents
Hypromellose (Type II,Viscosity:400mPa.s) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-A0104G

HPMC (Type II,Viscosity:4000mPa.s) Hypromellose (Type II,Viscosity:4000mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:4000mPa.s); Celacol HPM 5000 (Type II,Viscosity:4000mPa.s)	Biochemical Assay Reagents
Hypromellose (Type II,Viscosity:4000mPa.s) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W112941

(meso-Tetraphenylporphinato)platinum Pt(II) Meso-Tetraphenylporphine	Biochemical Assay Reagents
Meso- tetraphenylporphyrin - pt(ii) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127778

Ammonium disodium pentacyanoammineferrate(II) Pentacyanoamine ferrate ammonium disodium	Biochemical Assay Reagents
Ammonium disodium pentacyanoammineferrate(II) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P2983

Angiotensin-converting enzyme ACE; kininase II; CD143	Biochemical Assay Reagents
Angiotensin-converting enzyme (ACE) is a dicarboxypeptidase, it converts inactive Angiotensin I (Ang I) to active Ang II and degrades active bradykinin (BK). Angiotensin-converting enzyme is a potent vasoconstrictor, is often used in biochemical studies .

HY-21623

Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct	Biochemical Assay Reagents
Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-D0874

HEPPSO	Biochemical Assay Reagents
HEPPSO is a zwitterionic buffer. The working pH range of HEPPSO buffer is 7.1-8.5. HEPPSO displays relatively high ability to bind copper(II), has a pK_a of 7.84 at 2.0 mM buffer concentration .

HY-E70139

UDP-GalNAc:β-1,3-N-acetylgalactosaminyltransferase 2 EC:2.4.1.313; B3GALNT2; β-1,3-N-acetylgalactosaminyltransferase II	Enzyme Substrates
UDP-GalNAc:β-1,3-N-acetylgalactosaminyltransferase 2 ( EC:2.4.1.313; B3GALNT2; β-1,3-N-acetylgalactosaminyltransferase II) is a glycosyltransferase .

HY-135269

Quin II potassium

Dyes

QUIN 2, Tetrapotassium Salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W001951

Dirhodium tetraacetate Tetrakis(acetato)dirhodium(II); Rhodium(II) acetate dimer	Biochemical Assay Reagents
Dirhodium tetraacetate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W145693

Difucosyl-para-lacto-N-hexaose	Biochemical Assay Reagents
Difucosyl-para-lacto-N-hexaose II (DFpLNH II) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W073189

Magnesium(II) meso-tetraphenylporphine	Biochemical Assay Reagents
Magnesium meso-tetraphenylporphine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-156630

Ionizable lipid-1

Drug Delivery

Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .

HY-156630A

Ionizable lipid-1 hydrochloride	Drug Delivery
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .

HY-141627

Heparin disaccharide I-S tetrasodium

Biochemical Assay Reagents

Heparin carbohydrate IS tetrasodium is the major disaccharide produced by heparinases I and II from heparin.

HY-157917

Nitro-PAPS disodium dihydrate	Chelators
Nitro-PAPS disodium dihydrate is a highly sensitive colometric reagent for Fe(II) detection with a maximal absorption wavelength of 592 nm. Nitro-PAPS disodium dihydrate is suitable for the determination of Fe(II) in serum and also be used to determine micro molar levels of Cu, Zn, Ni, Co and V .

HY-131162

Chymase	Biochemical Assay Reagents
Chymase is a protein-digester enzyme found primarily in mast cells (MC), fibroblasts, and vascular endothelial cells. Chymase is released into the extracellular stroma in the context of inflammatory signals, tissue injury and cellular stress. Chymase is also involved in angiotensin II (Ang II) production, which is used in cardiovascular disease studies .

HY-W004650

TETA hydrochloride hydrate

Chelators

TETA hydrochloride hydrate is an effective selective chelating agent for copper (II). TETA hydrochloride hydrate can be used for drug coupling .

HY-W134005

Mg(Ⅱ)-EDTA disodium tetrahydrate Ethylenediaminetetraacetic acid magnesium disodium tetrahydrate	Chelators
Mg(II)-EDTA (disodium tetrahydrate) is an ion-chelating agent that can be used to prepare reagents for ion-sensitive experiments .

HY-125857

Cytochrome C	Biochemical Assay Reagents
Cytochrome C is a multi-functional enzyme involving in life and death decisions of the cell. Cytochrome C is essential in mitochondrial electron transport and intrinsic type II apoptosis .

HY-E70144

N-Acetylglucosaminyltransferase 1 EC:2.4.1.101; MGAT1	Enzyme Substrates
N-Acetylglucosaminyltransferase1 (EC:2.4.1.101, MGAT1) shows typical features of a type II transmembrane protein. N-Acetylglucosaminyltransferase1 is believed to be essential for normal embryogenesis .

HY-P2990

Enteropeptidase TMPRSS15	Biochemical Assay Reagents
Enteropeptidase (TMPRSS15), a type II transmembrane serine protease and a physiological activator of trypsinogen. Enteropeptidase is associated with the brush border membrane (BBM) of the enterocytes in the upper small intestine. Trypsinogen is the primary substrate for Enteropeptidase. Enteropeptidase is involved in digestion in humans and animals .

HY-W250316

Alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate Sucrose Stearate, Type II, USP	Biochemical Assay Reagents
Alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate is a carbohydrate.

HY-W127790

Bathophenanthrolinedisulfonic acid disodium

Biochemical Assay Reagents

Bathophenanthrolinedisulfonic acid disodium salt is used as a colorimetric reagent for the detection of iron. It is widely used for the determination of iron in aqueous solutions without the use of extraction solvents. It is used as a precursor for the preparation of the anion Europium(III) disulfonated bathophenanthroline tris(dibenzoylformic acid) complex and ruthenium II tris(rubphenanthroline disulfonate). It plays a crucial role in the catalytic oxidation of 2-hexanol by enabling it to form a water-soluble complex with palladium.

HY-16700G

PNU-159682 (GMP)	Biochemical Assay Reagents
PNU-159682 GMP is a GMP grade PNU-159682 (HY-16700). PNU-159682, a metabolite of the anthracycline Nemorubicin, is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity. PNU-159682 acts as a more potent and tolerated ADC cytotoxin than Doxorubicin for ADC synthesis. PNU-159682 can be used in EDV-nanocell technology to overcome agent resistance.

HY-112764

DMG-PEG 2000 4 Publications Verification	Drug Delivery
DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .

Cat. No.	Product Name	Target	Research Area

HY-P1165

Urotensin II-related peptide	Urotensin Receptor	Cardiovascular Disease
Urotensin II-related peptide is a human urotensin II anague. Urotensin II-related peptide has high affinity for the UT receptor .

HY-P1168

[Orn8]-Urotensin II (human)	Urotensin Receptor	Cardiovascular Disease
[Orn8]-Urotensin II (human), a peptide analog of urotensin II, is a UT receptor agonist. [Orn8]-Urotensin II (human) increases intracellular calcium levels in HEK293 .

HY-P2643

Angiotensin I/II (4-8)

Endogenous Metabolite Cardiovascular Disease

Angiotensin I/II (4-8), a major metabolite of Angiotensin II, is a C-terminal 4-8 pentapeptide .

HY-P10108

Hexokinase II VDAC binding domain peptide Hxk2VBD peptide	Hexokinase	Neurological Disease
Hexokinase II VDAC binding domain peptide (Hxk2VBD peptide) is a cell-permeable hexokinase II VDAC binding domain. Hexokinase II VDAC binding domain peptide inhibits mitochondrial localization of hexokinase 2 (HXK2). Hexokinase II VDAC binding domain peptide inhibits neurotrophic factor-directed axon outgrowth .

HY-P3771

p60c-src substrate II, phosphorylated	Peptides	Others
p60c-src substrate II, phosphorylated is a pentapeptide. p60c-src substrate II, phosphorylated is a p60c-src substrate II phosphorylated polypeptide. Protein phosphorylation is an important post-translationmodification of protein that is indispensible in biological regulations .

HY-P2212

Angiotensin amide (Asn1,Val5)-Angiotensin II	Angiotensin Receptor	Inflammation/Immunology
Angiotensin amide ((Asn1,Val5)-Angiotensin II) is a potent vasoconstrictor. Angiotensin amide is a derivative of angiotensin II. Angiotensin amide can be used as a cardiac activator .

HY-P3570

Adipokinetic hormone II (Locusta migratoria) Lom-AKH-II	Endogenous Metabolite	Metabolic Disease
Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) .

HY-13948

Angiotensin II human Maximum Cited Publications 93 Publications Verification Angiotensin II; Ang II; DRVYIHPF	Angiotensin Receptor Apoptosis	Cardiovascular Disease Endocrinology Cancer
Angiotensin II (Angiotensin II) is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .

HY-13948A

Angiotensin II human acetate Maximum Cited Publications 93 Publications Verification Angiotensin II acetate; Ang II acetate; DRVYIHPF acetate	Angiotensin Receptor Apoptosis	Cardiovascular Disease Endocrinology Cancer
Angiotensin II human (Angiotensin II) acetate is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human acetate plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human acetate stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human acetate induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human acetate also induces apoptosis. Angiotensin II human acetate induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .

HY-P3633

Locustatachykinin II Lom-TK II	Peptides	Neurological Disease
Locustatachykinin II (Lom-TK II) is an insect neuropeptide with homology to peptides of the vertebrate tachykinin family. Locustatachykinin II can be used for the research of insect endocrine .

HY-13948B

Angiotensin II human TFA Maximum Cited Publications 93 Publications Verification Angiotensin II TFA; Ang II TFA; DRVYIHPF TFA	Angiotensin Receptor Apoptosis	Cardiovascular Disease Endocrinology Cancer
Angiotensin II human (Angiotensin II) TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human TFA plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human TFA stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human TFA induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human TFA also induces apoptosis. Angiotensin II human TFA induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .

HY-P3635

Cockroach Myoactive Peptide II Pea-CAH-II	Peptides	Neurological Disease Metabolic Disease
Cockroach Myoactive Peptide II (Pea-CAH-II) is a cockroach neuropeptide. Cockroach Myoactive Peptide II is a member of the adipokinetic hormone/red pigment concentrating hormone (AKH/RPCH) family. Cockroach Myoactive Peptide II can be used for the research of metabolic functions of insect body .

HY-P1763

Urechistachykinin II Uru-TK II	Bacterial	Infection
Urechistachykinin II (Uru-TK II), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect .

HY-P5652

Bombolitin II

Peptides Infection

Bombolitin II is an antimicrobial peptide derived from bumblebee venom. Bombolitin II can lysate erythrocyte and liposome .

HY-13948F

Biotin-Ahx-Angiotensin II human Biotin-Ahx-Angiotensin II; Biotin-Ahx-Ang II; Biotin-Ahx-DRVYIHPF	Peptides	Others
Biotin-Ahx-Angiotensin II human (Biotin-Ahx-Angiotensin II; Biotin-Ahx-Ang II; Biotin-Ahx-DRVYIHPF) is a biological active peptide. (biotin labeled HY-13948)

HY-13948F1

Angiotensin II human, FAM-labeled Angiotensin II, FAM-labeled ; Ang II, FAM-labeled ; DRVYIHPF, FAM-labeled	Peptides	Others
Angiotensin II human, FAM-labeled (Angiotensin II, FAM-labeled ; Ang II, FAM-labeled ; DRVYIHPF, FAM-labeled) is a biological active peptide. (FAM labeled HY-13948)

HY-P3050

Helospectin II	Peptides	Cardiovascular Disease
Helospectin II is a neuropeptide of the vasoactive intestinal peptide (VIP) family. Helospectin II has vasodilatory and antihypertensive activities, and decreases blood pressure. Helospectin II is originally isolated from the salivary gland venom of the lizard Heloderma suspectum .

HY-P5144

Aah II

Sodium Channel Inflammation/Immunology

Aah II is a sodium channel modulator. Aah II is a toxin that can be isolated from the venom of scorpion Androctonus australis .

HY-W140282

Angiotensin II antipeptide	Angiotensin Receptor	Cardiovascular Disease
Angiotensin II antipeptide, a peptide, is an inverse agonist of AR1 receptor. Angiotensin II antipeptide is encoded by mRNA, complementary to that encoding Angiotensin II (HY-13948) itself .

HY-P5818

BDS-II

Sodium Channel Neurological Disease

BDS-II is a peptide toxin, and is composed of 43 amino acids. BDS-II is a selective Kv3.4 channel inhibitor .

HY-P1604

ATX-II	Sodium Channel	Inflammation/Immunology
ATX-II is a specific Na ⁺ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II causes delayed inactivation of the Na ⁺II sensitizes skeletal muscle to Halothane (HY-B1010), Caffeine, and Ryanodine (HY-103306). ATX-II also induces pulmonary vein arrhythmogenesis and atrial fibrillation .

HY-P1483

Urotensin II, mouse	Urotensin Receptor	Cardiovascular Disease Neurological Disease
Urotensin II, mouse is an endogenous ligand for the orphan G-protein-coupled receptor GPR14 or SENR. Urotensin II, mouse is a potent vasoconstrictor. Urotensin II, mouse plays a physiological role in the central nervous system .

HY-P1483B

Urotensin II, mouse acetate	Urotensin Receptor	Cardiovascular Disease Neurological Disease
Urotensin II, mouse acetate is an endogenous ligand for the orphan G-protein-coupled receptor GPR14 or SENR. Urotensin II, mouse acetate is a potent vasoconstrictor. Urotensin II, mouse acetate plays a physiological role in the central nervous system .

HY-P5067

EAK16-II

Peptides Others

EAK16-II is an amphipathic peptide that inhibits the self-sorting of EAKIIH6 in a concentration-dependent manner .

HY-P5954

PLTX-II	Peptides	Others
PLTX-II is a calcium channel blocker. PLTX-II has a 44-residue peptide containing ten Cys residues and an O-palmitoylated threonine amide at the carboxy-terminus .

HY-P5177

GsAF-II	Sodium Channel Potassium Channel	Neurological Disease
GsAF-II is a peptide toxin that blocks hERG1 subtype potassium channels in a voltage-dependent manner. GsAF-II blocks Nav1.x subtype sodium channels .

HY-P3748

Casein Kinase II Receptor Peptide	Casein Kinase	Others
Casein Kinase II Receptor Peptide is a substrate for casein kinase II with an K_m value of 500 µM. Casein Kinase II Substrate can be used for measure casein kinase II activity in crude enzyme preparations .

HY-P0108

Angiotensin II 5-valine

Valine angiotensin II; 5-L-Valine angiotensin II
Angiotensin Receptor Endocrinology Cancer

Angiotensin II 5-valine is an agonist of angiotensin receptor.
HY-P3728

Interleukin II (60-70)

Interleukin Related Inflammation/Immunology

Interleukin II (60-70) is a 60-70 fragment of the cytokine Interleukin II polypeptide .

HY-P1722

Spantide II	Neurokinin Receptor	Inflammation/Immunology
Spantide II, an undecapeptide substance P (SP) analog, is a potent neurokinin-1 receptor (NK-1R) antagonist. Spantide II binds with NK-1R and blocks proinflammatory activities associated with SP. Spantide II can be used in the research of inflammatory skin disorders, such as psoriasis and contact dermatitis .

HY-P1604A

ATX-II TFA	Sodium Channel	Inflammation/Immunology
ATX-II TFA is a specific Na ⁺ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II TFA causes delayed inactivation of the Na ⁺II TFA sensitizes skeletal muscle to Halothane (HY-B1010), Caffeine, and Ryanodine (HY-103306). ATX-II TFA also induces pulmonary vein arrhythmogenesis and atrial fibrillation .

HY-P1769

Angiotensin II (5-8), human	Angiotensin Receptor	Metabolic Disease Endocrinology
Angiotensin II (5-8), human is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II . Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca ²⁺ levels. Angiotensin II also acts at the Na ⁺/H ⁺ exchanger in the proximal tubules of the kidney .

HY-P1483A

Urotensin II, mouse TFA	Urotensin Receptor	Cardiovascular Disease Neurological Disease
Urotensin II, mouse TFA is an endogenous ligand for the orphan G-protein-coupled receptor GPR14 or SENR. Urotensin II, mouse TFA is a potent vasoconstrictor. Urotensin II, mouse TFA plays a physiological role in the central nervous system .

HY-P3138

(Sar1)-Angiotensin II	Angiotensin Receptor	Cardiovascular Disease
(Sar1)-Angiotensin II, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. (Sar1)-Angiotensin II binds to brain membrane-rich particles, with a K_d of 2.7 nM. (Sar1)-Angiotensin II can stimulate protein synthesis and cell growth in embryonic chick myocytes .

HY-P3921

Casein Kinase II Substrate

Casein Kinase Cancer

Casein Kinase II Substrate is a casein kinase II (CK2) peptide substrate that can be selectively phosphorylated by CK2 .

HY-P1630

Buforin II	Bacterial	Infection
Buforin II, derived from buforin I, a protein isolated from the stomach of the Asian toad Bufo bufo gargarizans, is a potent antimicrobial peptide. Buforin II has antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria .

HY-P3967

Thymopoietin i/ii (29-41) (bovine)	Peptides	Neurological Disease
Thymopoietin i/ii (29-41) (bovine) is a peptide corresponding to positions 29-41 of bovine thymopoietin II. Thymopoietin i/ii (29-41) (bovine) is a neuromuscular blocker .

HY-P5772

Jingzhaotoxin-II	Sodium Channel	Neurological Disease
Jingzhaotoxin-II, a 32 amino acid residues including two acidic and two basic residues, is a neurotoxin. Jingzhaotoxin-II inhibits voltage-gated sodium channels (VGSC) that significantly slows rapid inactivation of TTX-resistant (TTX-R) VGSC on cardiac myocytes with the IC₅₀ of 0.26 μM .

HY-P1874

Calmodulin-Dependent Protein Kinase II (281-309)	Calmodulin	Neurological Disease
Calmodulin-Dependent Protein Kinase II (281-309) is a peptide of calcium/calmodulin-dependent protein kinase II (CaM-kinase II) .

HY-P1792

Angiotensin II (1-4), human	Angiotensin Receptor	Metabolic Disease Endocrinology
Angiotensin II (1-4), human is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca ²⁺ levels. Angiotensin II also acts at the Na ⁺/H ⁺ exchanger in the proximal tubules of the kidney .

HY-P1786

Allatostatin II

Peptides Neurological Disease

Allatostatin II is a decapeptid. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects .

HY-P1839

Angiotensin I/II (1-5)	Angiotensin Receptor	Cardiovascular Disease
Angiotensin I/II 1-5 is a peptide that contains the amino acids 1-5, which is converted from Angiotensin I/II. Angiotensin I is formed by the action of renin on angiotensinogen. Angiotensin II is produced from angiotensin I. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy .

HY-P5003

Collagen Type II Fragment	Biochemical Assay Reagents	Inflammation/Immunology
Collagen Type II Fragment is an anti-inflammatory peptide that potently inhibits collagen-induced arthritis (CIA) in mice. Collagen Type II Fragment can be used for research on inflammation and immunity .

HY-P2955

Heparinase II

Peptides Others

Heparinase II is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P1829

Angiotensin I/II (1-6)	Angiotensin Receptor	Cardiovascular Disease
Angiotensin I/II 1-6 contains the amino acids 1-6 and is converted from Angiotensin I/II peptide. The precursor angiotensinogen is cleaved by renin to form angiotensin I. Angiotensin I ishydrolyzed by angiotensin-converting enzyme (ACE) to form the biologically active angiotensin II. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy .

HY-P3630

Stick Insect Hypertrehalosaemic Factor II	Peptides	Others
Stick Insect Hypertrehalosaemic Factor II is a synthetic peptide. Stick Insect Hypertrehalosaemic Factor II has the same FAB spectra, reversed-phase high-performance liquid chromatographic behavior, and biological behavior as the natural material. Stick Insect Hypertrehalosaemic Factor II can be used for the research of hypertrehalosaemic effect .

HY-P1792A

Angiotensin II (1-4), human TFA	Angiotensin Receptor	Metabolic Disease Endocrinology
Angiotensin II (1-4), human (TFA) is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca ²⁺ levels. Angiotensin II also acts at the Na ⁺/H ⁺ exchanger in the proximal tubules of the kidney .

HY-P1221

ProTx II	Sodium Channel	Neurological Disease
ProTx II is a selective blocker of Nav1.7 sodium channels with an IC₅₀ of 0.3 nM, and is at least 100-fold selective for Nav1.7 over other sodium channel subtypes. ProTx-II inhibits sodium channels by decreasing channel conductance and shifting activation to more positive potentials and blocks action potential propagation in nociceptors .

HY-P1839A

Angiotensin I/II (1-5) (TFA)	Angiotensin Receptor	Cardiovascular Disease
Angiotensin I/II 1-5 TFA is a peptide that contains the amino acids 1-5, which is converted from Angiotensin I/II. Angiotensin I is formed by the action of renin on angiotensinogen. Angiotensin II is produced from angiotensin I. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy .

HY-P1588

Scyliorhinin II	Neurokinin Receptor	Neurological Disease Endocrinology
Scyliorhinin II is a selective neurokinin-3 receptor agonist, with a K_i of 2.5 nM for neurokinin-3 receptor in rat cerebral cortex.

Cat. No.	Product Name

HY-KE7012

Dpn II

Dpn II is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Mbo I, Sau3A I, Bsp143 I, BstMB I, Nde II, BstKT I.

HY-K0022

Phosphatase Inhibitor Cocktail II Maximum Cited Publications 316 Publications Verification
Phosphatase Inhibitor Cocktail II effectively inhibits acid and alkaline phosphatases as well as protein tyrosine phosphatases(PTPs).

HY-KE7006

Bgl II

Bgl II is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products.
HY-KE7032

Pvu II

Pvu II is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products.
HY-KE7014

EcoR I

EcoR I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Fun II.
HY-KE7002

Avr II

Avr II is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: AspA2 I, Bln I, XmaJ I.

HY-K0510A

RT Master Mix for qPCR II 50+ Cited Publications
MCE RT Master Mix for qPCR II is a convenient, ready-to-use formulation for reverse transcription. With advanced reverse transcriptase, this kit can synthesize cDNA more rapidly, more specifically.

HY-KE7009

BstE II

BstE II is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: BstP I, Eco91 I, EcoO65 I, PspE I.

HY-KE7053

EcoR I, ADCF
EcoR I, ADCF is animal derived component free, and has good redundancy of enzyme activity, which can easily cope with excessive substrate or difficult template enzyme cutting. Isoschizomers: Fun II.

HY-KE7034

Sac II

Sac II is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Cfr42 I, Ksp I, Sfr303 I, SgrB I.
HY-KE7033

Sac I

Sac I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Psp124B I, Sst I, Ecl136 II, EcoICR I.
HY-KE7008

BstB I

BstB I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Asu II, Bpu14 I, Bsp119 I, BspT104 I, Nsp V, Sfu I.

HY-K0511A

RT Master Mix for qPCR II (gDNA digester plus) 10+ Cited Publications
MCE RT Master Mix for qPCR II is a convenient, ready-to-use formulation for reverse transcription and can eliminate genomic DNA (gDNA) contaminations in RNA samples. With updated reverse transcriptase, this kit can synthesize cDNA more rapidly, more specifically.

Cat. No.	Product Name	Target	Research Area

HY-P9910

Obinutuzumab GA101; Anti-Human CD20 type II, Humanized Antibody	CD20	Cancer
Obinutuzumab (GA101) a novel glycoengineered Type II CD20 humanized IgG1 monoclonal antibody in development for non-Hodgkin lymphoma.

HY-P990184

Anti-Mouse MHC Class II (βchain) Antibody (KL277)	Inhibitory Antibodies	Others
Anti-Mouse MHC Class II (βchain) Antibody (KL277) is a hamster/mouse-derived IgG type antibody inhibitor, targeting to mouse MHC Class II.

HY-P990189

Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243)	Inhibitory Antibodies	Others
Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to monkey/human MHC class II.

HY-P990188

Anti-Mouse MHC class II (I-A) Antibody (Y-3P)	Inhibitory Antibodies	Others
Anti-Mouse MHC class II (I-A) Antibody (Y-3P) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse MHC class II.

HY-P990187

Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114)	Inhibitory Antibodies	Others
Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) is a rat-derived IgG2b type antibody inhibitor, targeting to mouse MHC Class II.

HY-P990185

Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S)	Inhibitory Antibodies	Others
Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse/rat MHC Class II.

HY-P990186

Anti-Mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2)	Inhibitory Antibodies	Others
Anti-Mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2) is a mouse-derived IgG2c, κ type antibody inhibitor, targeting to mouse MHC Class II.

HY-P99922

Encelimab	Inhibitory Antibodies	Cancer
Encelimab is an anti-LAG3 antibody. Encelimab blocks the interaction between LAG-3 and MHC II, and enhances T-cell activation. Encelimab alone or in combination with an anti-PD-1 antibody reduces tumor size in a lymphoma mice model (A20 cell xenograft) .

HY-P99613

Favezelimab MK-4280	LAG-3	Cancer
Favezelimab (MK-4280) is a humanized anti-LAG-3 monoclonal antibody that blocks the interaction between LAG-3 and its ligand MHC class II. Favezelimab has the potential for colorectal cancer (CRC) research combined with the PD-L1 inhibitor Pembrolizumab (HY-P9902) .

HY-P99739

Miromavimab

M777-16-3
Inhibitory Antibodies Infection

Miromavimab (M777-16-3) is a anti-rabies virus strain ERAGP ectodomainepitope G-II mAb .
HY-P99954

Rivabazumab pegol

Bacterial Infection

Rivabazumab pegol is a PcrV protein antibody that can be used to study the phase II pegylated Fab of chronic Pseudomonas aeruginosa infection .

HY-P99797

Pabinafusp alfa JR-141	Transferrin Receptor	Neurological Disease
Pabinafusp alfa (JR-141) is a transferrin receptor-targeting antibody consisting of Iduronate 2-sulfatase (HY-P76399) and an anti-human transferrin receptor antibody. Pabinafusp alfa is blood-brain permeable and prevents heparan sulfate (HS) deposition in the central nervous system of mucopolysaccharidosis II (MPS II) mice. Pabinafusp alfa improves learning and prevents central nervous system neuronal damage in mice .

HY-P99027

Ieramilimab LAG525; IMP701	LAG-3	Cancer
Ieramilimab (LAG525; IMP701) is a humanized IgG4 monoclonal antibody that binds to LAG-3, resulting in inhibition of LAG-3 interaction with MHC-II molecules .

HY-P99736

Miptenalimab BI-754111	LAG-3	Cancer
Miptenalimab (BI-754111) is an anti-human LAG-3 antibody (K_D: 88.6 nM for h LAG-3). Miptenalimab blocks the interaction of LAG-3 with its ligand MHC-II .

HY-P99355

Bimagrumab 1 Publications Verification Anti-ACVR2B Reference Antibody; BYM338	TGF-β Receptor	Metabolic Disease
Bimagrumab (Anti-ACVR2B Reference Antibody) is a human monoclonal antibody that blocks activin type II receptor (ActRII), with K_Ds of 1.7 pM and 434 pM for human ActRIIB and ActRIIA, respectively. Bimagrumab can be used for the research of pathological muscle loss and weakness .

HY-P99933

Eftilagimod alfa IMP321; LAG-3Ig	LAG-3	Cancer
Eftilagimod alfa (IMP321) is a recombinant LAG-3Ig fusion protein that binds to MHC class II. Eftilagimod alfa mediates antigen-presenting cell (APC) activation followed by CD8 T-cell activation. Eftilagimod alfa can be used for metastatic melanoma and metastatic breast carcinoma research .

HY-P99156

Relatlimab BMS-986016	LAG-3	Cancer
Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC₅₀ value of 0.67 nM and LAG-3/FGL1 interaction with an IC₅₀ value of 0.019 nM. Relatlimab can be used in research of cancer .

HY-P99171

Gevokizumab	Interleukin Related	Inflammation/Immunology
Gevokizumab is a potent anti-IL-1β antibody, negatively modulates IL-1β signaling through an allosteric mechanism. Gevokizumab selectively decreases the binding affinity of IL-1β for the IL-1 receptor type I (IL-1RI) signaling receptor instead of IL-1 counter-regulatory decoy receptor (IL-1 receptor type II) .

HY-P99437

Anbenitamab KN-026	EGFR	Cancer
Anbenitamab (KN-026) is a bispecific antibody simultaneously targeting the extracellular domains II and IV of the human HER2. Anbenitamab blocks both ligand-dependent and ligand-independent HER2 signaling pathway. The IgG1 Fc fragment of Anbenitamab binds FcRγIIIa mediates potent antibody dependent cell-mediated cytotoxicity (ADCC) and inhibits tumor cell proliferation. Anbenitamab has the potential for HER2-positive metastatic breast cancer (MBC) research .

HY-P99573

Tebotelimab MGD-013	LAG-3	Inflammation/Immunology Cancer
Tebotelimab (MGD-013) is a humanized IgG4κ bispecific PD-1/LAG-3 dual-affinity re-targeting (DART) antibody. Tebotelimab binds cell-surface expressed PD-1 and LAG-3 with EC₅₀s of 1.65 nM and 0.41 nM in NS0 cells, respectively. Tebotelimab blocks PD-1/PD-L1, PD-1/PD-L2 and LAG-3/HLA (MHC-II) interactions and PD-1 signaling. Tebotelimab restores exhausted T-cell responses and and enhances antitumour immunity .

Species:	Human (137) Virus (4) Rhesus Macaque (6) Mouse (35) Rat (10) Bovine (1) Cynomolgus (9) E.coli (1) Staphylococcus aureus (1)
Tag:	His (150) SUMO (11) T7 (1) Tag Free (28) Strep (2) Avi (16) Myc (6) GST (20) MBP (2) Fc (25) Flag (4)
Source:	HEK293 (104) E. coli Cell-free (9) CHO (2) Sf9 insect cells (2) CHO (1) Sf9 insect cells (25) P. pastoris (5) E. coli (67)

Cat. No.	Compare	Product Name	Species	Source

HY-P78262

	CD74 Protein, Mouse (224a.a, HEK293, His) CD74; II; DHLAG; HLADG; Ia-GAMMA; p33; CLIP; INVG34; Ia-GAMMA ; II	Mouse	HEK293
	The CD74 protein is significantly expressed in the thymus and lymph nodes, suggesting that it plays a key role in regulating immune system function. Its presence in the thymus, a key site for T cell development, underscores its important role in overseeing key cellular processes required for immune maturation. CD74 Protein, Mouse (224a.a, HEK293, His) is the recombinant mouse-derived CD74 protein, expressed by HEK293 , with N-His labeled tag. The total length of CD74 Protein, Mouse (224a.a, HEK293, His) is 224 a.a., with molecular weight of 40-50 kDa.

HY-P72931

	CD74 Protein, Human (HEK293, His) HLA class II histocompatibility antigen gamma chain; CD74; CLIP; DHLAG	Human	HEK293
	CD74 is a key component of the class II major histocompatibility complex and serves as a key chaperone in antigen presentation in the regulation of immune responses. It doubles as a cell surface receptor for macrophage migration inhibitory factor (MIF), initiating survival pathways and cell proliferation. CD74 Protein, Human (HEK293, His) is the recombinant human-derived CD74 protein, expressed by HEK293 , with N-His labeled tag. The total length of CD74 Protein, Human (HEK293, His) is 160 a.a., with molecular weight of 30-40 kDa.

HY-P72710

	CD74 Protein, Mouse (160a.a, HEK293, His) H-2 class II histocompatibility antigen gamma chain; CD74; CLIP; DHLAG	Mouse	HEK293
	The CD74 protein is significantly expressed in the thymus and lymph nodes, suggesting that it plays a key role in regulating immune system function. Its presence in the thymus, a key site for T cell development, underscores its important role in overseeing key cellular processes required for immune maturation. CD74 Protein, Mouse (160a.a, HEK293, His) is the recombinant mouse-derived CD74 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD74 Protein, Mouse (160a.a, HEK293, His) is 160 a.a., with molecular weight of 25-30 kDa.

HY-P70205

	Progonadoliberin-2/GNRH II Protein, Human (HEK293, His) rHuProgonadoliberin-2/GnRH II, His; Progonadoliberin-2; Progonadoliberin II; Gonadoliberin-2; Gonadoliberin II; Gonadotropin-Releasing Hormone II; GnRH II; Luliberin II; Luteinizing Hormone-Releasing Hormone II; LH-RH II; GnRH-Associated Peptide 2; GnRH-Associated Peptide II; GNRH2	Human	HEK293
	Progonadoliberin-2/GNRH II Proteinas, a pivotal player in the endocrine system, potently stimulates gonadotropin secretion, promoting both luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release. Its capacity to orchestrate the secretion of these hormones underscores its significance in governing reproductive functions within the intricate endocrine signaling network that regulates the reproductive axis. Progonadoliberin-2/GNRH II Protein, Human (HEK293, His) is the recombinant human-derived Progonadoliberin-2/GNRH II protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Progonadoliberin-2/GNRH II Protein, Human (HEK293, His) is 97 a.a., with molecular weight of 15-24 kDa.

HY-P7669

	BMPR-II Protein, Human (HEK293, His) rHuBMPR-II, His; BMP Type-2 Receptor; BMP Type II Receptor; BMPR-II; BMPR2	Human	HEK293
	BMP Type II Receptor (BMPR2) is a type II member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. BMPR2 is highly expressed in the heart and liver, and involves in osteogenesis and cell differentiation, essential for embryogenesis, development, and adult tissue homeostasis. BMPR2 is associated with tubulin stability, the inhibition of BMPR2 destabilizes the microtubules promoting cell death of cancer cells that involves the activation of the lysosomes. Human BMPR2 protein contains 1038 amino acids and a transmembrane domain (151-171 a.a.). BMPR-II Protein, Human (HEK293, His) is the extracellular part of the complete BMPR2 protein, produced by HEK293 cells (S27-I151) with C-terminal 6*His-tag.

HY-P7156

	EMAP-II Protein, Human rHuEMAP-II; Endothelial-Monocyte A Activating Polypeptide II; EMAP-2; AIMP1	Human	E. coli
	EMAP-II Protein, Human is a proinflammatory cytokine and chemoattractant of macrophages.

HY-P700666

	BSP2 Protein, Cynomolgus (HEK293, His) BNSP; BSP 2; BSP II; BSP; BSP-II; IBSP; SP II; SPII; SP-II	Cynomolgus	HEK293
	BSP2 protein, with robust hydroxyapatite binding, is integral to the mineralized matrix, shaping the structural framework of tissues. Its association implies a crucial role in cell-matrix interactions, influencing both physical and functional aspects. BSP2 also promotes RGD-dependent cell attachment, underscoring its involvement in cellular adhesion processes. The tight binding to hydroxyapatite underscores BSP2's significance in modulating cell-matrix dynamics within biological systems. BSP2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived BSP2 protein, expressed by HEK293, with C-His labeled tag. The total length of BSP2 Protein, Cynomolgus (HEK293, His) is 302 a.a., with molecular weight of 60-80 kDa.

HY-P70228

	Kanamycin kinase type II/NEO protein, Klebsiella pneumoniae rKlAminoglycoside 3'-phosphotransferase; Aminoglycoside 3'-phosphotransferase; APH(3')-II; APH(3')II; Kanamycin kinase type II; Neomycin-kanamycin phosphotransferase type II; neo	Others	E. coli
	The Kanamycin kinase type II/NEO protein imparts resistance to aminoglycoside antibiotics, including kanamycin, neomycin, paromomycin, ribostamycin, butirosin, and gentamicin B. It counteracts their inhibitory effects, showcasing the protein's versatility in mitigating the impact of various antibiotics and enabling the organism to thrive in their presence. Kanamycin kinase type II/NEO protein, Klebsiella pneumoniae is the recombinant Kanamycin kinase type II/NEO protein, expressed by E. coli , with tag free. The total length of Kanamycin kinase type II/NEO protein, Klebsiella pneumoniae is 264 a.a., with molecular weight of 26-30 kDa.

HY-P70228A

	Kanamycin kinase type II/NEO protein, Klebsiella pneumoniae (Tag Free) rKlAminoglycoside 3'-phosphotransferase; Aminoglycoside 3'-phosphotransferase; APH(3')-II; APH(3')II; Kanamycin kinase type II; Neomycin-kanamycin phosphotransferase type II; neo	Others	E. coli
	The Kanamycin kinase type II/NEO protein imparts resistance to aminoglycoside antibiotics, including kanamycin, neomycin, paromomycin, ribostamycin, butirosin, and gentamicin B. It counteracts their inhibitory effects, showcasing the protein's versatility in mitigating the impact of various antibiotics and enabling the organism to thrive in their presence. Kanamycin kinase type II/NEO protein, Klebsiella pneumoniae (Tag Free) is the recombinant Kanamycin kinase type II/NEO protein, expressed by E. coli , with tag free. The total length of Kanamycin kinase type II/NEO protein, Klebsiella pneumoniae (Tag Free) is 264 a.a., with molecular weight of approximately 29.68 kDa.

HY-P701933

	ADH II Protein, Zymomonas mobilis subsp. mobilis adhB; Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II	Others	E. coli
	ADH II Protein, an iron-dependent alcohol dehydrogenase, is pivotal in converting pyruvate to ethanol. This enzymatic activity is essential for pathways involving ethanol formation, contributing to physiological processes in alcohol metabolism. Its iron dependency underscores intricate biochemical mechanisms, emphasizing ADH II's significance in producing ethanol from pyruvate within relevant biological contexts. ADH II Protein, Zymomonas mobilis subsp. mobilis is the recombinant ADH II protein, expressed by E. coli , with tag free. The total length of ADH II Protein, Zymomonas mobilis subsp. mobilis is 382 a.a., .

HY-P72296

	DNA helicase II/uvrD Protein, E.coli pdeB; DNA helicase II	E.coli	E. coli
	DNA helicase II/uvrD protein, a DNA-dependent ATPase, efficiently unwinds DNA duplexes with 3' to 5' polarity, especially from nicked substrates. It actively participates in post-incision stages of nucleotide excision repair and methyl-directed mismatch repair, contributing to genomic integrity by facilitating DNA unwinding in various repair mechanisms. DNA helicase II/uvrD Protein, E.coli is the recombinant E. coli-derived DNA helicase II/uvrD protein, expressed by E. coli, with tag free. The total length of DNA helicase II/uvrD Protein, E.coli is 720 a.a., with molecular weight of ~82.0 kDa.

HY-P7527

	Apolipoprotein A-II/APOA2 Protein, Human (HEK293, His) rHuApolipoprotein A-II, His; ApoA2; Apolipoprotein A-II	Human	HEK293
	Apolipoprotein A-II/ApoA2 Protein, Human (HEK293, His) expresses in HEK293 with a His tag at the N-terminus. Apolipoprotein A-II (ApoA-II) has been associated with numerous aspects of HDL metabolism, and apoA-II overexpression produces the proatherogenic phenotype.

HY-P77562

	Apolipoprotein A-II/APOA2 Protein, Mouse (HEK293, Fc) Apolipoprotein A-II; Apo-AII; Apolipoprotein A2; ProapoA-II; Apolipoprotein A-II(1-76); APOA2	Mouse	HEK293
	Apolipoprotein A-II/APOA2 protein may stabilize high-density lipoprotein (HDL) structure and affect HDL metabolism through lipid association. As a monomer, APOA2 is critical for maintaining HDL integrity and function. Apolipoprotein A-II/APOA2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Apolipoprotein A-II/APOA2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Apolipoprotein A-II/APOA2 Protein, Mouse (HEK293, Fc) is 84 a.a., with molecular weight of 40-45 kDa.

HY-P701934

	ADH II Protein, Zymomonas mobilis subsp. mobilis (His, Strep) adhB; Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II	Others	E. coli
	ADH II Protein, an iron-dependent alcohol dehydrogenase, is pivotal in converting pyruvate to ethanol. This enzymatic activity is essential for pathways involving ethanol formation, contributing to physiological processes in alcohol metabolism. Its iron dependency underscores intricate biochemical mechanisms, emphasizing ADH II's significance in producing ethanol from pyruvate within relevant biological contexts. ADH II Protein, Zymomonas mobilis subsp. mobilis (His, Strep) is the recombinant ADH II protein, expressed by E. coli , with N-Strep, N-6*His labeled tag. The total length of ADH II Protein, Zymomonas mobilis subsp. mobilis (His, Strep) is 382 a.a., .

HY-P7407

	SHH Protein, Human (C24II) rHuSonic Hedgehog, C24II; HHG1	Human	E. coli
	SHH Protein, Human (C24II) is a recombinant human sonic hedgehog variant. SHH Protein is a secreted signal transducer responsible not only for patterning of the anterior–posterior axis during early limb and neuronal development, but also for generating cell-type diversity at later developmental stages.

HY-P7409

SHH Protein, Mouse (C25II)

2 Publications Verification

rMuSonic Hedgehog, C25II; Hhg1
Mouse E. coli

SHH Protein, Mouse (C25II) is a recombinant mouse sonic hedgehog variant.
HY-P702180

NADH dehydrogenase Protein type II, Gluconobacter oxydans

GOX1675; NADH dehydrogenase type II
Others E. coli

HY-P7529

	APOC2 Protein, Human (His) rHuApolipoprotein C-II, His; ApoC2; Apolipoprotein C-II	Human	E. coli
	Apolipoprotein C-II Protein, Human (His) is expressed in E. coli with a His tag at the N-terminus. Apolipoprotein C-II Protein, Human (His) has a pharmacological application for the treatment of patients with genetic hypertriglyceridemia caused by ApoC-II otein C-II Protein, Human (His) is expressed in E. coli with a His tag at the C-terminus. Apolipoprotein C-II Protein, Human (His) has a pharmacological application for the treatment of patients with genetic hypertriglyceridemia caused by ApoC-II deficiency.

HY-P72944

	Coagulation Factor II/F2 Protein, Mouse (HEK293, His) Prothrombin; Coagulation factor II	Mouse	HEK293
	Coagulation Factor II/F2, also known as thrombin, functions as a pivotal serine protease. Its enzymatic action involves cleaving bonds after Arg and Lys residues, facilitating the conversion of fibrinogen to fibrin. Thrombin additionally activates key factors like V, VII, VIII, XIII, and, in conjunction with thrombomodulin, protein C. Beyond blood homeostasis, thrombin plays a role in inflammation and the complex dynamics of wound healing. Coagulation Factor II/F2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Coagulation Factor II/F2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor II/F2 Protein, Mouse (HEK293, His) is 594 a.a., with molecular weight of ~85 kDa.

HY-P74241

	Coagulation Factor II/F2 Protein, Rat (HEK293, His) Prothrombin; Coagulation factor II	Rat	HEK293
	The factor II/F2 protein (also known as thrombin) plays a key role in blood homeostasis, inflammation, and wound healing. As a multifunctional enzyme, it catalyzes the conversion of fibrinogen into fibrin to form the coagulation network. Coagulation Factor II/F2 Protein, Rat (HEK293, His) is the recombinant rat-derived Coagulation Factor II/F2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor II/F2 Protein, Rat (HEK293, His) is 593 a.a., with molecular weight of ~69.5 kDa.

HY-P702181

NADH dehydrogenase Protein type II, Gluconobacter oxydans (His)

GOX1675; NADH dehydrogenase type II
Others E. coli

HY-P71690

	GLO2/Glyoxalase II Protein, Human (GST) HAGH; GLO2; HAGH1Hydroxyacylglutathione hydrolase; mitochondrial; EC 3.1.2.6; Glyoxalase II; Glx II	Human	E. coli
	GLO2, or Glyoxalase II Protein, serves as a thiolesterase, playing a crucial role in catalyzing the hydrolysis of S-D-lactoyl-glutathione. This activity generates glutathione and D-lactic acid, emphasizing GLO2's significance in cellular metabolism. The enzyme contributes to regulating glutathione levels and the conversion of substrates within cellular pathways. GLO2/Glyoxalase II Protein, Human (GST) is the recombinant human-derived GLO2/Glyoxalase II protein, expressed by E. coli , with N-GST labeled tag. The total length of GLO2/Glyoxalase II Protein, Human (GST) is 259 a.a., with molecular weight of ~55.7 kDa.

HY-P77643

	EMAP-II Protein, Mouse (His) EMAP-2; EMAP-II; AIMP1; HLD3; SCYE1; p43	Mouse	E. coli
	EMAP-II is a noncatalytic component of the multisynthase complex (MSC) and plays a critical role in coordinating tRNA ligase function. It stimulates cytoplasmic arginyl-tRNA synthase and binds to tRNA. EMAP-II Protein, Mouse (His) is the recombinant mouse-derived EMAP-II protein, expressed by E. coli , with N-His labeled tag. The total length of EMAP-II Protein, Mouse (His) is 309 a.a., with molecular weight of 42-46 kDa.

HY-P702298

	GNRHR2 Protein, Rhesus Macaque (Cell-Free, His) Gonadotropin-releasing hormone II receptor; Type II GnRH receptor	Rhesus Macaque	E. coli Cell-free
	The GNRHR2 Protein serves as a receptor for gonadotropin-releasing hormone II (GnRH II), initiating its action through association with G proteins that activate a phosphatidylinositol-calcium second messenger system. GNRHR2 Protein, Rhesus Macaque (Cell-Free, His) is the recombinant Rhesus Macaque-derived GNRHR2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of GNRHR2 Protein, Rhesus Macaque (Cell-Free, His) is 379 a.a., with molecular weight of 44.3 kDa.

HY-P701720

	CAMK2D Protein, Human (Sf9, GST) CAMK2D; Calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II subunit delta; CaMK-II subunit delta	Human	Sf9 insect cells
	CAMK2D protein regulates calcium levels and excitation-contraction coupling in the heart. CAMK2D Protein, Human (Sf9, GST) is the recombinant human-derived CAMK2D protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of CAMK2D Protein, Human (Sf9, GST) is 498 a.a., .

HY-P73906

	IGF2 Protein, Human (P.pastoris) Insulin-like growth factor II; IGF-II; Preptin; IGF2; PP1446	Human	P. pastoris
	The IGF2 protein is an important member of the insulin-like growth factor family and plays an important role in mammalian growth, fetoplacental development, and adult glucose metabolism. Regulated by placental prolactin, affecting tissue differentiation. IGF2 Protein, Human (P.pastoris) is the recombinant human-derived IGF2 protein, expressed by P. pastoris , with tag free. The total length of IGF2 Protein, Human (P.pastoris) is 67 a.a., with molecular weight of ~7.5 kDa.

HY-P78215

	TGFBR2/TGF-beta RII Protein, Human (Biotinylated, HEK293, Fc-Avi) TGFR2; TGFBR2; TbetaR-II; TGFβR2; TbetaR-II; TGFβR2; AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TβR-II; TβR-II	Human	HEK293
	The TGFBR2/TGF-β RII protein cooperates with TGFBR1 to form dedicated receptors for TGFB1, TGFB2, and TGFB3. It serves as a signal transducer that coordinates diverse physiological and pathological processes, including cell cycle regulation, mesenchymal cell dynamics, wound healing, matrix production, immunosuppression, and carcinogenesis. TGFBR2/TGF-beta RII Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived TGFBR2/TGF-beta RII protein, expressed by HEK293 , with C-Avi, C-mFc labeled tag. The total length of TGFBR2/TGF-beta RII Protein, Human (Biotinylated, HEK293, Fc-Avi) is 136 a.a., with molecular weight of 55-70 kDa.

HY-P78524

	TGFBR2/TGF-beta RII Protein, Human (HEK293, mFc-Avi) 1 Publications Verification TGFR2; TGFBR2; TbetaR-II; TGFβR2; TbetaR-II; TGFβR2; AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TβR-II; TβR-II	Human	HEK293
	The TGFBR2/TGF-β RII protein cooperates with TGFBR1 to form dedicated receptors for TGFB1, TGFB2, and TGFB3. It serves as a signal transducer that coordinates diverse physiological and pathological processes, including cell cycle regulation, mesenchymal cell dynamics, wound healing, matrix production, immunosuppression, and carcinogenesis. TGFBR2/TGF-beta RII Protein, Human (HEK293, mFc-Avi) is the recombinant human-derived TGFBR2/TGF-beta RII protein, expressed by HEK293 , with C-Avi, C-mFc labeled tag. The total length of TGFBR2/TGF-beta RII Protein, Human (HEK293, mFc-Avi) is 136 a.a., with molecular weight of 55-70 kDa.

HY-P71455

	SVMP Protein, Crotalus adamanteus (His) Snake venom metalloproteinase adamalysin-2; SVMP; EC 3.4.24.46; Adamalysin II; Proteinase II	Others	E. coli
	SVMP protein, while lacking significant hemorrhagic activity, functions by inactivating serpins through limited proteolysis of their reactive-site loops. SVMP Protein, Crotalus adamanteus (His) is the recombinant SVMP protein, expressed by E. coli , with N-6*His labeled tag. The total length of SVMP Protein, Crotalus adamanteus (His) is 203 a.a., with molecular weight of ~27.1 kDa.

HY-P72855

	BMPR-II Protein, Human (HEK293, His-Fc) Bone morphogenetic protein receptor type-2; BMPR-2; BMPR-II; PPH1	Human	HEK293
	BMP Type II Receptor (BMPR2) is a type II member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. BMPR2 is highly expressed in the heart and liver, and involves in osteogenesis and cell differentiation, essential for embryogenesis, development, and adult tissue homeostasis. BMPR2 is associated with tubulin stability, the inhibition of BMPR2 destabilizes the microtubules promoting cell death of cancer cells that involves the activation of the lysosomes. Human BMPR2 protein contains 1038 amino acids and a transmembrane domain (151-171 a.a.). BMPR-II Protein, Human (HEK293, His-Fc) is the extracellular part of the complete BMPR2 protein, produced by HEK293 cells (M1-I151) with C-terminal hFc- and His-tag.

HY-P71108

	PRPS2 Protein, Human (HEK293, His) Ribose-Phosphate Pyrophosphokinase 2; PPRibP; Phosphoribosyl Pyrophosphate Synthase II; PRS-II; PRPS2	Human	HEK293
	The PRPS2 protein plays a key role in catalyzing the synthesis of phosphoribosyl pyrophosphate (PRPP), a key intermediate in nucleotide synthesis. By promoting the conversion of ribose 5-phosphate and ATP to PRPP, PRPS2 contributes to the availability of PRPP in various cellular processes, including de novo biosynthesis of purine and pyrimidine nucleotides. PRPS2 Protein, Human (HEK293, His) is the recombinant human-derived PRPS2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PRPS2 Protein, Human (HEK293, His) is 317 a.a., with molecular weight of ~37.0 kDa.

HY-P71249

	RBP2 Protein, Human Retinol-binding protein 2; Cellular retinol-binding protein II; CRBP-II; RBP2; CRBP2	Human	E. coli
	RBP2 is pivotal for intracellular retinol transport. RBP2 Protein, Human is the recombinant human-derived RBP2 protein, expressed by E. coli , with tag free. The total length of RBP2 Protein, Human is 134 a.a., with molecular weight of ~16.78 kDa.

HY-P700596

	CSNK2A2 Protein, Human (His-SUMO) Casein kinase 2 alpha 1 polypeptide; Casein kinase II alpha 1; Casein kinase II alpha 1 subunit; Casein kinase II alpha subunit; Casein kinase II subunit alpha; CK II alpha; CK II; CK2 alpha; CK2 catalytic subunit alpha; CK2A1; CKII; CKIIalpha; CSK21_HUMAN; CSNK2A1	Human	E. coli
	CSNK2A2 is the catalytic subunit of the serine/threonine protein kinase complex. It regulates important processes such as cell cycle, apoptosis, and transcription, and affects viral infection. During mitosis, CSNK2A2 maintains CDK1 activity and induces cell cycle arrest. In addition, CSNK2A2 phosphorylates p53/TP53 and negatively regulates apoptosis. It widely affects cell signaling, phosphorylated caspases, the apoptotic factor NOL3, and RNA polymerase, among others. CSNK2A2 also regulates Wnt signaling and acts as a kinase for extracellular proteins. CSNK2A2 Protein, Human (His-SUMO) is the recombinant human-derived CSNK2A2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of CSNK2A2 Protein, Human (His-SUMO) is 343 a.a., with molecular weight of 56.7 kDa.

HY-P70221

	Acyl-protein thioesterase 2/LYPLA2 Protein, Human (His) rHuAcyl-protein thioesterase 2/LYPLA2, His; Acyl-Protein Thioesterase 2; APT-2; Lysophospholipase II; LPL-II; LysoPLA II; LYPLA2; APT2	Human	E. coli
	Acyl-protein thioesterase 2/LYPLA2 Protein, Human (His) a protein palmitoyl thioesterase, is a cytosolic enzyme that catalyze depalmitoylation of membrane-anchored, growth-associated protein-43 (GAP-43).

HY-P71696

	HLA-DPB1 Protein, Human (His) HLA class II histocompatibility antigen; HLA class II histocompatibility antigen; DP beta 1 chain; HLA class II histocompatibility antigen; HLA-DP1B; HLA-DPB	Human	E. coli
	The HLA-DPB1 protein is an integral part of the immune system, binding antigens in the endocytic pathway of antigen-presenting cells (APCs). It presents the peptide on the cell surface for recognition by CD4 T cells. HLA-DPB1 Protein, Human (His) is the recombinant human-derived HLA-DPB1 protein, expressed by E. coli , with N-His labeled tag. The total length of HLA-DPB1 Protein, Human (His) is 194 a.a., with molecular weight of ~26.8 kDa.

HY-P76574

	RPN2/Ribophorin II Protein, Human (HEK293, Fc) Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; RIBIIR; RPN-II; RPN2	Human	HEK293
	RPN2/riboprotein II is a key subunit of the oligosaccharyltransferase (OST) complex, which catalyzes the initial glycan transfer during co-translational protein N-glycosylation. This critical step occurs in the nascent polypeptide chain and involves the transfer of defined glycans from polyhydroxypyrophosphate to asparagine residues in the Asn-X-Ser/Thr motif. RPN2/Ribophorin II Protein, Human (HEK293, Fc) is the recombinant human-derived RPN2/Ribophorin II protein, expressed by HEK293 , with C-hFc labeled tag. The total length of RPN2/Ribophorin II Protein, Human (HEK293, Fc) is 540 a.a., with molecular weight of ~84 kDa.

HY-P76575

	RPN2/Ribophorin II Protein, Human (HEK293, His) Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; RIBIIR; RPN-II; RPN2	Human	HEK293
	RPN2/riboprotein II is a key subunit of the oligosaccharyltransferase (OST) complex, which catalyzes the initial glycan transfer during co-translational protein N-glycosylation. This critical step occurs in the nascent polypeptide chain and involves the transfer of defined glycans from polyhydroxypyrophosphate to asparagine residues in the Asn-X-Ser/Thr motif. RPN2/Ribophorin II Protein, Human (HEK293, His) is the recombinant human-derived RPN2/Ribophorin II protein, expressed by HEK293 , with C-His labeled tag. The total length of RPN2/Ribophorin II Protein, Human (HEK293, His) is 518 a.a., with molecular weight of ~60 kDa.

HY-P77199

	Serpin D1 Protein, Human (HEK293, His) Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2	Human	HEK293
	Serpin D1 protein is a thrombin inhibitor activated by glycosaminoglycans such as heparin or dermatan sulfate. It replaces antithrombin III and becomes the main thrombin inhibitor in the presence of dermatan sulfate. In addition to thrombin inhibition, serpin D1 also has glycosaminoglycan-independent chymotrypsin inhibitory activity. Serpin D1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin D1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin D1 Protein, Human (HEK293, His) is 480 a.a., with molecular weight of ~75-80 kDa.

HY-P79250

MCV-type II Chemokine-like Protein, Virus

C-C chemokine-like protein; MC148R; MC148; Molluscum Contagiosum Virus Type II
Virus E. coli

HY-P72834

	APP/Protease Nexin-II Protein, Human (HEK293, Fc) Amyloid-beta precursor protein; APP; CVAP; PN-II; PreA4; A4; AD1	Human	HEK293
	There is no specific Pubmed ID mentioned in the paragraph. APP/Protease Nexin-II Protein, Human (HEK293, Fc) is the recombinant human-derived APP/Protease Nexin-II protein, expressed by HEK293 , with C-hFc labeled tag. The total length of APP/Protease Nexin-II Protein, Human (HEK293, Fc) is 652 a.a., with molecular weight of 150-160 kDa.

HY-P76157

	ASF1B Protein, Human (sf9, His) Histone chaperone ASF1B; hAsf1b; CCG1-interacting factor A-II; CIA-II	Human	Sf9 insect cells
	The ASF1B protein is an important histone chaperone that crucially promotes histone deposition and coordinates exchange and removal during nucleosome assembly and disassembly, which has been verified by various studies. ASF1B cooperates with CAF-1 to promote replication-dependent chromatin assembly. ASF1B Protein, Human (sf9, His) is the recombinant human-derived ASF1B protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of ASF1B Protein, Human (sf9, His) is 202 a.a., with molecular weight of ~20 KDa.

HY-P7019

	IGF2 Protein, Human 2 Publications Verification rHuIGF-2; Somatamedin A; IGF-II	Human	E. coli
	IGF2 Protein, Human is a mitogenic cytokine, binds to IGF type 1 receptor, and modulates growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle, endothelium, and bone.

HY-P7338

	DHH Protein, Human (C23II) rHuDHH; DHH; HHG-3	Human	E. coli
	DHH Protein, Human is a single non-glycosylated polypeptide chain. Desert hedgehog protein (DHH) is a member of the Hedgehog family which encodes signaling molecules that play an important role in regulating morphogenesis.

HY-P70410

	MGAT2 Protein, Human (HEK293, His) rHuAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase/MGAT2, His ; Alpha-1; 6-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase; Beta-1; 2-N-acetylglucosaminyltransferase II; GlcNAc-T II; NT-II; Mannoside Acetylglucosaminyltransferase 2; N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase II; MGAT2	Human	HEK293
	The MGAT2 protein plays an important role in protein N-glycosylation, catalyzing the transfer of GlcNAc to the free terminal mannose in nascent N-linked glycan chains. This forms a second branch of the complex glycan and is critical for glycoprotein maturation and functional diversity. MGAT2 Protein, Human (HEK293, His) is the recombinant human-derived MGAT2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of MGAT2 Protein, Human (HEK293, His) is 418 a.a., with molecular weight of ~50.0 kDa.

HY-P71293

	Serpin D1 Protein, Mouse (HEK293, His) Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2; Serpin D1	Mouse	HEK293
	Serpin D1 is a thrombin inhibitor that is activated by glycosaminoglycans such as heparin or dermatan sulfate. In the presence of dermatan sulfate, HC-II surpasses antithrombin III (AT) as the primary thrombin inhibitor. Serpin D1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin D1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin D1 Protein, Mouse (HEK293, His) is 455 a.a., with molecular weight of 70-90 kDa.

HY-P71697

	HLA-DPA1 Protein, Human (His) HLA-DPA1; HLA-DP1A; HLASBHLA class II histocompatibility antigen; DP alpha 1 chain; HLA-SB alpha chain; MHC class II DP3-alpha; MHC class II DPA1	Human	E. coli
	The HLA-DPA1 protein is critical in the immune system, binding antigens in the endocytic pathway of APCs and presenting them to the cell surface for recognition by CD4 T cells. The peptide binding cleft can accommodate peptides of 10-30 residues, mainly resulting from protein degradation. HLA-DPA1 Protein, Human (His) is the recombinant human-derived HLA-DPA1 protein, expressed by E. coli , with N-His labeled tag. The total length of HLA-DPA1 Protein, Human (His) is 194 a.a., with molecular weight of ~26.3 kDa.

HY-P7426

	TGFBR2/TGF-beta RII Protein, Human (HEK293, Fc) TGFR-2; TGF-beta type II receptor; TGF-beta receptor type 2; TbetaR-II	Human	HEK293
	TGF-beta receptor 2 Protein, Human (HEK293, Fc), a fragment of transforming growth factor-beta receptor type 2 (TβRII), consists of amino acid of Thr23-Asp159 with an Fc tag at the C-terminus.

HY-P7427

	TGFBR2/TGF-beta RII Protein, Mouse (HEK293, Fc) TGFR-2; TGF-beta type II receptor; TGF-beta receptor type 2; TbetaR-II	Mouse	HEK293
	TGFBR2/TGF-beta RII Protein, Mouse (HEK293, Fc), a fragment of transforming growth factor-beta receptor type 2 (TβRII), consists of amino acid of Ile24-Asp159 with a 6His tag at the C-terminus.

HY-P7428

	TGFBR2/TGF-beta RII Protein, Mouse (HEK293, His) TGFR-2; TGF-beta type II receptor; TGF-beta receptor type 2; TbetaR-II	Mouse	HEK293
	TGFBR2/TGF-beta RII Protein, Mouse (HEK293, His), His consists of N-terminal ectodomain and C-terminal protein kinase domain with his tag. TGF-beta receptor type-2 is the ligand-binding receptor for all members of the TGF-β family.

HY-P73428

	TGFBR2/TGF-beta RII Protein, Human (sf9, His) TGFR-2; TGF-beta type II receptor; TGF-beta receptor type 2; TbetaR-II	Human	Sf9 insect cells
	The TGFBR2/TGF-β RII protein cooperates with TGFBR1 to form dedicated receptors for TGFB1, TGFB2, and TGFB3. It serves as a signal transducer that coordinates diverse physiological and pathological processes, including cell cycle regulation, mesenchymal cell dynamics, wound healing, matrix production, immunosuppression, and carcinogenesis. TGFBR2/TGF-beta RII Protein, Human (sf9, His) is the recombinant human-derived TGFBR2/TGF-beta RII protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of TGFBR2/TGF-beta RII Protein, Human (sf9, His) is 144 a.a., with molecular weight of ~24 kDa.

Cat. No.	Product Name	Application	Reactivity

HY-P81537

CD74 Antibody (YA1282) CD74; DHLAG; HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; II; p33; CD74	IHC-P	Human

HY-P81524

VIPR1 Antibody (YA1269)

vasoactive inTinal peptide receptor 1; II; HVR1; RDC1; V1RG; VIPR; VIRG; VAPC1; VPAC1; VPAC1R; VIP-R-1; VPCAP1R; PACAP-R2; PACAP-R-2
IHC-P Human

HY-P81039

Strep-Tag II Antibody (YA885) Strep-Tag II；Strep Tag	WB, IF-Cell, IP	Species-independent
Strep-Tag II Antibody (YA885) is an unconjugated, rabbit-derived, anti-Strep-Tag II (YA885) monoclonal antibody. Strep-Tag II Antibody (YA885) can be used for: WB、IF、IP expriments in species-independent background without labeling.

HY-P80980

TOP2A Antibody DNA topoisomerase II; DNA topoisomerase II-alpha; TOP2; TP2A; alpha isozyme, Topoisomerase II alpha	WB, IHC-P, IP	Human, Mouse, Rat
TOP2A Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 174 kDa, targeting to TOP2A. It can be used for WB, IHC-P, IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P81907

CRABP2 Antibody (YA1652)

Cellular retinoic acid-binding protein II; CRABP-II
WB, ICC/IF Human
HY-P82918

DDX21 Antibody (YA2663)

GUA; GURDB; RH-II/GU; RH-II/GuA
WB, ICC/IF Human

HY-P81047

Collagen II Antibody Collagen II alpha 1; COL2A1; COL2A1 protein; collagen, type II, alpha 1; collagen alpha-1(II); type II collagen; alpha-1 type II collagen; alpha1 type II collagen; Col2a1; AOM; Cartilage collagen; Chondrocalcin; COL11A3; Collagen alpha 1(II) chain precursor; Collagen II alpha 1 polypeptide; Collagen type II alpha 1 (primary osteoarthritis spondyloepiphyseal dysplasia congenital); MGC131516; SEDC; Collagen alpha-1(II) chain; Alpha-1 type II collagen; CO2A1_HUMAN.; CollagenII;	WB, ELISA, IHC-P, IF	Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Guinea Pig
Collagen II Antibody is an unconjugated, approximately 117 KDa, rabbit-derived, anti-Collagen II polyclonal antibody. Collagen II Antibody can be used for: WB, ELISA, IHC-P, IF expriments in human, mouse, rat, chicken, dog, pig, cow, rabbit, guinea pig background without labeling.

HY-P81514

Uroplakin II/UPII Antibody (YA1259)

UPK2; Uroplakin-2; UP2; Uroplakin II (UPII)
IHC-P Human

HY-P82599

CaMKII beta Antibody (YA2344) CAMK2B; CAM2; CAMK2; CAMKB; Calcium/calmodulin-dependent protein kinase type II subunit beta; CaM kinase II subunit beta; CaMK-II subunit beta; CAMK2G; CAMK; CAMK-II; CAMKG; Calcium/calmodulin-dependent protein kinase type II subunit gamma	WB	Mouse

HY-P82592

CaMKII delta Antibody (YA2337)

CAM kinase 2 delta; CAM kinase II delta; CaM kinase II delta subunit; CaM kinase II subunit delta; CAMK 2d; CaMK-II delta subunit; CAMK2D; CAMKI
WB Human, Rat

HY-P80703

Hexokinase II Antibody HKII; HXK2	WB, IHC-P, IP	Human, Rat, Hamster
Hexokinase II Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 102 kDa, targeting to Hexokinase II. It can be used for WB,IHC-P,IP assays with tag free, in the background of Human, Rat, Hamster.

HY-P80445

CaMKII alpha Antibody 1 Publications Verification Alpha CaMKII; Calcium calmodulin dependent protein kinase II; Calcium/calmodulin dependent protein kinase II alpha B subunit; Calcium/calmodulin dependent protein kinase type II alpha chain; Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; Calcium/calmodulin-dependent protein kinase II alpha; Calcium/calmodulin-dependent protein kinase II-alpha; Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase type IIA; CaM kinase II alpha chain; CaM kinase II alpha subunit; CaM kinase II subunit alpha; CaMK II alpha subunit; CaMK-II subunit alpha; Camk2a; CAMKA; CaMKII; CaMKIINalpha; EC2.7.11.17; KCC2A_HUMAN; KIAA0968; MGC123320; MGC139375; MGC155201; mKIAA0968; PK2CDD; PKCCD; R74975; zgc:112538; zgc:123320;	WB, IP, FC, IHC-P	Human, Mouse, Rat
CaMKII alpha Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 54 kDa, targeting to CaMKII alpha. It can be used for WB,IP,FC,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P83617

Carbonic Anhydrase 2 Antibody (YA3362)

CA2; Carbonic anhydrase 2; Carbonate dehydratase II; Carbonic anhydrase C; CAC; Carbonic anhydrase II; CA-II
WB, IHC-P Human, Mouse, Rat

HY-P80883

RNA Polymerase II Subunit B1 Antibody POLR2A; POLR2; DNA-directed RNA polymerase II subunit RPB1; RNA polymerase II subunit B1; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase III largest subunit; RNA-directed RNA polymerase II subunit RPB1	WB, IHC-F, IHC-P, ICC/IF, IP	Human
RNA Polymerase II Subunit B1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 217 kDa, targeting to RNA Polymerase II Subunit B1. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human.

HY-P82926

Cytokeratin 2e Antibody (YA2671) KRT2; KRT76; KRT3; KRT5; KRT6A; KRT6B; KRT6C; KRT71; KRT72; KRT73; KRT74; KRT75; KRT79; KRT8; KRT84; Keratin; type II cytoskeletal 2 epidermal; Keratin; type II cytoskeletal 2 oral; Keratin; type II cytoskeletal 3; Keratin; type II cytoskeletal 5; Keratin; type II cytoskeletal 6A; Keratin; type II cytoskeletal 6B; Keratin; type II cytoskeletal 6C; Keratin; type II cytoskeletal 71; Keratin; type II cytoskeletal 72; Keratin; type II cytoskeletal 73; Keratin; type II cytoskeletal 74	WB, IHC-P	Human

HY-P81332

ntpII Antibody (YA1077)

neomycin phosphotransferase II
WB Transfected

HY-P81243

F2 Antibody Des-gamma-carboxy (abnormal)prothrombin; Des-Gamma-carboxy-prothrombin; coagulation factor II (thrombin); Coagulation factor II; DCP; Factor II; Prepro coagulation factor II; Prothrombin; prothrombin B-chain; PT; RPRGL2; serine protease; THPH1; THRB; THRB_HUMAN; Thrombin heavy chain.	WB=1:500-2000; ELISA=1:5000-10000; IHC-P=1:100-500; IHC-F=1:100-500; Flow-Cyt=1ug/test; IF=1:100-500	Human, Mouse, Rat

HY-P83345

AGTR2 Antibody (YA3090) AGTR2; Angiotensin II receptor type 2; Angiotensin II type-2 receptor; AT2 receptor; AT2; At2r; MRX88; Angiotensin II at2; Angiotensin receptor 2; Type-2 angiotensin II receptor; ATGR2	WB, IP	Human, Mouse, Rat

HY-P81491

INPP4B Antibody (YA1236) 4-bisphosphate 4-phosphatase; Inositol polyphosphate 4 phosphatase type II 105kDa; Inositol polyphosphate 4-phosphatase type II; Inpp4b; MGC132014; Type II inositol 3; 4 bisphosphate 4 phosphatase; Type II inositol-3	IHC-P	Human

HY-P80969

BNSP Antibody integrin binding sialoprotein; BSP; BNSP; SP-II; BSP-II；IBSP; Bone sialoprotein II; Cell binding sialoprotein; Integrin binding sialoprotein; SIAL_HUMAN; Bone sialoprotein 2; Cell-binding sialoprotein; Integrin-binding sialoprotein.	WB, IHC-P, IHC-F, IF, ELISA	Mouse, Rat (predicted: Human)
IBSP Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 35 kDa, targeting to IBSP. It can be used for WB, IHC-P assays with tag free, in the background of Human, Mouse.

HY-P81714

ApoA2 Antibody (YA1459)

APO A2; Apo AII; APOA 2; ApoA II; APOA2; APOAII; Apolipoprotein A II
WB, ICC/IF, FC Human, Rat
HY-P83339

HLA DR Antibody (YA3084)

MLRW; HLA-DRA1; MHC class II antigen DRA; HLA class II histocompatibility antigen; DR alpha chain
WB, IHC-P, ICC/IF, FC Human
HY-P83088

CSNK2A1 Antibody (YA2833)

CSNK2A1; CK2A1; Casein kinase II subunit alpha; CK II alpha
WB Human, Mouse, Rat
HY-P83265

beta II Tubulin Antibody (YA3010)

class II beta tubulin isotype; Beta2; Tubulin beta 2 chain; TUBB; TUBB2
WB, IHC-P, ICC/IF, IP, FC Human, Mouse, Rat
HY-P82184

Complex III Subunit 2 Antibody (YA1929)

Core protein II; QCR2; mitochondrial; Ubiquinol cytochrome c reductase core protein II; UQCR2; Uqcrc2
WB, IHC-P, ICC/IF, IP, FC Human, Mouse, Rat

HY-P81312

Transcription Initiation Factor IIB Antibody (YA1054) General transcription factor IIB; General transcription factor TFIIB; gtf2b; RNA polymerase II transcription factor IIB; S300 II; S300-II; TF IIB; TF2B; TF2B_HUMAN; TFIIB; Transcription initiation factor IIB.	WB	Human, Mouse, Monkey

HY-P81312A

Transcription Initiation Factor IIB Antibody (YA1055) General transcription factor IIB; General transcription factor TFIIB; gtf2b; RNA polymerase II transcription factor IIB; S300 II; S300-II; TF IIB; TF2B; TF2B_HUMAN; TFIIB; Transcription initiation factor IIB.	WB, IP	Human, Mouse, Rat

HY-P83613

Angiotensin II Type 1 Receptor Antibody (YA3358)

AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B; Type-1 angiotensin II receptor; AT1AR; AT1BR; Angiotensin II type-1 receptor; AT1
WB Human

HY-P80586

Casein Kinase 2 beta Antibody CSNK2B; CK2N; G5A; Casein kinase II subunit beta; CK II beta; Phosvitin; Protein G5a	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
Casein Kinase 2 beta Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 25 kDa, targeting to Casein Kinase 2 beta. It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P81131

TGF beta Receptor II Antibody TGF-beta receptor type-2; TGF beta R2; TGFBR2; AAT 3; AAT3; FAA 3; FAA3; HNPCC6; MFS 2; MFS2; RIIC; TAAD 2; TAAD2; TbetaR II; TGF beta receptor type 2; TGF beta receptor type II; TGF beta type II receptor; TGFB R2; TGFbeta RII; TGFBR 2; TGFR 2; TGFR2; Transforming growth factor beta receptor II; Transforming growth factor beta receptor type II. TGF-βRⅡ; TGFβRⅡ; TGF βRⅡ; TGFβ RⅡ.	WB; ELISA; IHC-P; IHC-F; IF	Human, Mouse, Rat, Cow(predicted: Chicken, Pig, Horse, Rabbit, Sheep)
TGF beta Receptor II Antibody is an unconjugated, approximately 62 kDa, rabbit-derived, anti-TGF beta Receptor II polyclonal antibody. TGF beta Receptor II Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, rat, cow, and predicted: chicken, pig, horse, rabbit, sheep background without labeling.

HY-P81099

CGRP-1/2 Antibody CGRP-I + CGRP-II; CGRP-1/2; Procalcitonin; Beta type CGRP; CALC2; CALCB; Calcitonin 1; Calcitonin 2; Calcitonin gene related peptide; Calcitonin gene related peptide II; Calcitonin related polypeptide beta; CGRP; CGRP II; CGRP2; CT; Calcitonin/calcitonin related polypeptide alpha; Katacalcin; MGC126648; CALCA_HUMAN; CALCB_HUMAN; Calcitonin gene-related peptide 2; Beta-type CGRP; Beta-CGRP; Calcitonin gene-related peptide II; CGRP-II; CGRP-I.	ELISA; IHC-P; IHC-F; IF	Human, Rat(predicted: Mouse, Chicken, Pig, Cow)
CGRP-1/2 Antibody is an unconjugated, approximately 3.8/14 kDa, rabbit-derived, anti-CGRP-1/2 polyclonal antibody. CGRP-1/2 Antibody can be used for: ELISA, IHC-P, IHC-F, IF expriments in human, rat, and predicted: mouse, chicken, pig, cow background without labeling.

HY-P80945

Annexin VI Antibody p68; p70; ANX6; CBP68; CPB-II	WB, IHC-P, IP	Human, Mouse, Rat
Annexin VI Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 76 kDa, targeting to Annexin A6 (ANXA6). It can be used for WB,IHC-P,IP assays in the background of Human, Mouse, Rat.

HY-P80758

MSR1 Antibody Macrophage scavenger receptor types I and II; Macrophage acetylated LDL receptor I and II; Scavenger receptor class A member 1; CD204; MSR1; SCARA1	WB	Human, Mouse, Rat
MSR1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 50 kDa, targeting to MSR1. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P83260

Cytokeratin 8 Antibody (YA3005)

KRT8; CYK8; Keratin; type II cytoskeletal 8; Cytokeratin-8; CK-8; Keratin-8; K8; Type-II keratin Kb8
WB, IHC-P, ICC/IF, IP, FC Human, Mouse
HY-P83148

Arginase 2 Antibody (YA2893)

ARG2; Arginase-2; Type II arginase
WB, ICC/IF, FC Human
HY-P82346

IMPDH2 Antibody (YA2091)

IMPD2; IMPDH 2; IMPDH II; Impdh2
WB, IHC-P, ICC/IF, IP, FC Human, Mouse, Rat
HY-P82349

Angiotensin Converting Enzyme 1 Antibody (YA2094)

ACE; Dipeptidyl carboxypeptidase I; Kininase II
WB, IHC-P Mouse, Rat
HY-P82634

Desmoplakin Antibody (YA2379)

Desmoplakin I; Desmoplakin II; DPI; DPII; DSP; KPPS2; PPKS2
WB, ICC/IF, FC Human, Rat

HY-P81385

Amyloid Precursor Protein Antibody (YA1130) APP; A4; AD1; Amyloid beta A4 protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II	IHC-P	Human

HY-P82890

Phospho-Cytokeratin 8 (Ser23) Antibody (YA2635)

KRT8; CYK8; Keratin; type II cytoskeletal 8; Cytokeratin-8; CK-8; Keratin-8; K8; Type-II keratin Kb8
WB, IHC-F, IHC-P, ICC/IF, IP Human

HY-P82229

SKP1 Antibody (YA1974) SKP1; EMC19; OCP2; SKP1A; TCEB1L; S-phase kinase-associated protein 1; Cyclin-A/CDK2-associated protein p19; Organ of Corti protein 2; OCP-2; Organ of Corti protein II; OCP-II; RNA polymerase II elongation factor-like protein; SIII; Transcr	WB, ICC/IF	Human, Mouse, Rat

HY-P83018

EMAP II Antibody (YA2763)

p43; HLD3; EMAP2; SCYE1; EMAPII; AIMP1
WB Human, Rat

HY-P82823

Phospho-Amyloid Precursor Protein (Thr743) Antibody (YA2568) APP; A4; AD1; Amyloid beta A4 protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II	WB, ICC/IF, IP	Human, Rat

HY-P80978

PAX6 Antibody

PAX6; AN2; Paired box protein Pax-6; Aniridia type II protein; Oculorhombin
WB, IHC-P, ICC/IF Human, Mouse, Rat

PAX6 Antibody is an antibody targeting to PAX6.
HY-P82661

von Willebrand Factor Antibody (YA2406)

VWF; von Willebrand factor; von Willebrand antigen II; F8VWF
WB, IHC-P Rat
HY-P81702

DDAH2 Antibody (YA1447)

DDAH; DDAH II; DDAH2; DDAHII; Dimethylargininase 2; G6a
WB, IP Human, Mouse, Rat
HY-P82395

Kininogen 1 Antibody (YA2140)

BDK; Bradykinin; HMWK; Kallidin I; Kallidin II; KNG; KNG1; WILLIAMS FACTOR
WB, IHC-P, IP Human
HY-P83368

MYH9 Antibody (YA3113)

MHA; FTNS; EPSTS; BDPLT6; DFNA17; MATINS; NMMHCA; NMHC-II-A; NMMHC-IIA
WB, IHC-P, IP Human, Rat

HY-P82920

Cytokeratin 1 Antibody (YA2665) 67 kDa cytokeratin; CK1; EHK; Epidermolytic hyperkeratosis 1; EPPK; Hair alpha protein; K1; Keratin; KRT 1; KRT1A; NEPPK; type II cytoskeletal 1; Type-II keratin Kb1	WB	Human, Mouse, Rat

HY-P83505

CD32 Antibody (YA3250) FCGR2A; CD32; FCG2; FCGR2A1; IGFR2; Low affinity immunoglobulin gamma Fc region receptor II-a; IgG Fc receptor II-a; CDw32; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a; CD32	WB, IHC-P	Human

Cat. No.	Product Name		Classification

HY-16200

Ethynylcytidine ECyD; TAS-106; 3'-C-Ethynylcytidine		Alkynes
Ethynylcytidine (ECyD), a nucleoside analog and a potent inhibitor of RNA synthesis, inhibits RNA polymerases I, II and II. Ethynylcytidine has robust antitumor activity in a wide range of models of cancer . Ethynylcytidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-U00318

JAK-IN-11		Alkynes
JAK-IN-11 is a potent and selective JAK inhibitor extracted from patent WO2012122452A1, Compound II, has the potential for the skin disorders (such as cutaneous lupus) treatment . JAK-IN-11 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-128522

ARS-1323-alkyne		Alkynes
ARS-1323-alkyne, a switch-II pocket (S-IIP) inhibitor, is a conformational specific chemical reporter of KRAS ^G12C nucleotide state in living cells . ARS-1323-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130530

AP-C5		Alkynes
AP-C5 displays selective inhibition of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC₅₀ of 7.2, which can be used for the research of diarrheal disease . AP-C5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N11454

Lacto-N-neodifucohexaose II LNnDFH II		Azide
Lacto-N-neodifucohexaose II (Compd 9) is a derivative of key human milk tetrasaccharide . Lacto-N-neodifucohexaose II is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-151829

Fmoc-L-Asn(EDA-N3)-OH		Azide
Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II .

HY-134813

MRTX1133 3 Publications Verification		Alkynes
MRTX1133 is a noncovalent, potent, and selective KRAS G12D inhibitor. MRTX1133 optimally fills the switch II pocket and extends three substituents to favorably interact with the protein, resulting in an estimated K_D against KRAS G12D of 0.2 pM. MRTX1133 prevents SOS1-catalyzed nucleotide exchange and/or formation of the KRAS G12D/GTP/RAF1 complex, thereby inhibiting mutant KRAS-dependent signal transduction. MRTX1133 selectively inhibits KRAS G12D mutant, but not KRAS wild-type, tumor cells. MRTX1133 has single digit nanomolar activity in cellular assays and marked in vivo efficacy in tumor models harboring KRAS G12D mutations .

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