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Cat. No.: HY-N7751

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Isotanshinone II

Name: Isotanshinone II
Brand: MedChemExpress
SKU: HY-N7751
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1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Isotanshinone II is a natural product that can be isolated from Salvia glutinos. Isotanshinone II can be used to study Alzheimer's disease.

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CAS No.: 98249-39-9
Formule: C₁₈H₁₂O₃
Masse moléculaire:276.29

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Isotanshinone II Chemical Structure

CAS No.: 98249-39-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Publications (1)
Pureté et documentation
Références
Calculators
Help & FAQs
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Activité biologique

Description

Isotanshinone II is a natural product that can be isolated from Salvia glutinos. Isotanshinone II can be used to study Alzheimer's disease^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
AGS	IC₅₀	>20 μM Compound: 12, isotanshinone ii	Inhibition of HIF1 activation in human AGS cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay Inhibition of HIF1 activation in human AGS cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay	[PMID: 17583950]
AGS	IC₅₀	>50 μM Compound: 12, isotanshinone ii	Viability of human AGS cells under normoxic conditions after 24 hrs by MTT assay Viability of human AGS cells under normoxic conditions after 24 hrs by MTT assay	[PMID: 17583950]
Hep 3B2	IC₅₀	>20 μM Compound: 12, isotanshinone ii	Inhibition of HIF1 activation in human Hep3B cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay Inhibition of HIF1 activation in human Hep3B cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay	[PMID: 17583950]
Hep 3B2	IC₅₀	>50 μM Compound: 12, isotanshinone ii	Viability of human Hep3B cells under normoxic conditions after 24 hrs by MTT assay Viability of human Hep3B cells under normoxic conditions after 24 hrs by MTT assay	[PMID: 17583950]

Chemical Information

CAS No. 98249-39-9
Masse moléculaire 276.29
Formule C₁₈H₁₂O₃
SMILES

O=C(C1=C(C2=C3C=CC4=C2C=CC=C4C)OC=C1C)C3=O
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Labiatae
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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ACS Omega

Investigating the Mechanism of the Fuzheng Huayu Formula in Treating Cirrhosis through Network Pharmacology, Molecular Docking, and Experimental Verification. [Abstract]

2025 Apr 29;10(18):19019-19032. PMID: 40385224

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Samanta K, et al. An Expedite Synthesis of Some Angularly Fused Novel ‘U’‐Shaped Tetracyclic Furophenanthraquinones Simulating ABCD Rings of Isotanshinone‐II[J]. ChemistrySelect, 2021, 6(24): 6006-6010.

Calculators

Calculateur de molarité

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Isotanshinone II

1 Cited Publications

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Activité biologique
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Chemical Information
Publications (1)
Pureté et documentation
Références

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Isotanshinone II

Publications Citing Use of MedChemExpress (MCE) Isotanshinone II