CD66c/CEACAM6
CD66c/CEACAM6, a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family, is a GPI-anchored glycoprotein containing one IgV-like and two IgC-like domains. It is expressed on granulocytes and monocytes and on epithelia of the gastrointestinal tract, lung and breast. CEACAM6 promotes cell aggregation and aberrant epithelial differentiation, and its overexpression in pancreatic, colorectal, gastric and lung adenocarcinomas is associated with invasion, anoikis resistance and chemoresistance. It also functions as a receptor for pathogenic Neisseria species. Soluble CEACAM6 and serum antibodies against it are investigated as biomarkers, and the antigen is explored as an antibody-drug target.
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CD66c/CEACAM6 Recombinant Proteins (9)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
