MMP-26
MMP-26 (matrilysin-2, endometase) is an epithelium-specific matrixin that, like matrilysin/MMP-7, lacks the C-terminal hemopexin domain, and it is among the smallest members of the family. Expression is prominent in endometrium and placenta and in hormone-responsive carcinomas of breast, prostate and endometrium, under transcriptional control of estrogen and progesterone signaling. Notably, MMP-26 appears in preinvasive stages such as ductal carcinoma in situ, and its levels decline during tumor progression, suggesting a role in early neoplastic transformation rather than in late invasion. Reported activities include cleavage of basement-membrane components and activation of downstream matrixin cascades, and the enzyme is explored as an early-marker candidate in gynecologic oncology.
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MMP-26 Recombinant Proteins (1)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
