1. Others

Others

There are a number of inhibitors, agonists, and antagonists which we cannot make precise classification because the research area is still unknown.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-Y0873
    PEG300 25322-68-3
    PEG300 (Polyethylene glycol 300), a neutral polymer of molecular weight 300, is a water-soluble, low immunogenic and biocompatible polymer formed by repeating units of ethylene glycol.
    PEG300
  • HY-Y1891
    Tween 80 9005-65-6
    Tween 80 (Polysorbate 80), a surfactant, has been widely used as a solvent for pharmacological experiments. Tween 80 can also reduce bacterial attachment and inhibit biofilm formation.
    Tween 80
  • HY-Y1888
    Corn oil 8001-30-7
    Corn oil, extracted from the germ of corn, can be used as a carrier for agent molecules.
    Corn oil
  • HY-17031
    SBE-β-CD 182410-00-0 ≥98.0%
    SBE-β-CD is a sulfobutylether β-cyclodextrin derivative used as an excipient or a formulating agent to increase the solubility of poorly soluble agents.
    SBE-β-CD
  • HY-D0940
    H2DCFDA 4091-99-0 ≥98.0%
    H2DCFDA (DCFH-DA) is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS) (Ex/Em=488/525 nm).
    H2DCFDA
  • HY-W090090
    BODIPY 493/503 121207-31-6 ≥99.0%
    BODIPY493/503 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the polar lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells. Maximum excitation/emission wavelength: 493/503 nm.
    BODIPY 493/503
  • HY-Y0873A
    PEG400 25322-68-3
    PEG400 is a strongly hydrophilic polyethylene glycol used as an excellent solvent for a large number of substances. PEG400 is widely used in a variety of pharmaceutical formulations.
    PEG400
  • HY-12591B
    D-Luciferin potassium 115144-35-9 ≥98.0%
    D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP. We offer the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
    D-Luciferin potassium
  • HY-Y1893
    Solutol HS-15 61909-81-7
    Solutol HS-15, a Macrogol 15 hydroxy stearate, is a permeability enhancer.
    Solutol HS-15
  • HY-D0718
    Nile Red 7385-67-3 98.15%
    Nile red (Nile blue oxazone) is a lipophilic stain. Nile red has environment-sensitive fluorescence. Nile red is intensely fluorescent in a lipid-rich environment while it has minimal fluorescence in aqueous media. Nile red is an excellent vital stain for the detection of intracellular lipid droplets by fluorescence microscopy and flow cytof uorometry. Nile red stains intracellular lipid droplets red. The fluorescence wavelength is 559/635 nm.
    Nile Red
  • HY-66019
    FITC 3326-32-7 ≥98.0%
    FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity, excellent fluorescence quantum yield and good water solubility. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm.
    FITC
  • HY-15534
    JC-1 3520-43-2 ≥98.0%
    JC-1 (CBIC2) is an ideal fluorescent probe widely used to detect mitochondrial membrane potential. JC-1 accumulates in mitochondria in a potential dependent manner and can be used to detect the membrane potential of cells, tissues or purified mitochondria. In normal mitochondria, JC-1 aggregates in the mitochondrial matrix to form a polymer, which emits strong red fluorescence (Ex=585nm, Em=590nm); When the mitochondrial membrane potential is low, JC-1 cannot aggregate in the matrix of mitochondria and produce green fluorescence (ex=514nm, em=529nm).
    JC-1
  • HY-12270
    T-5224 530141-72-1 99.59%
    T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors. T-5224 inhibits the IL-1β-induced up-regulation of Mmp-3, Mmp-13 and Adamts-5 transcription.
    T-5224
  • HY-15979A
    H-89 dihydrochloride 130964-39-5 ≥98.0%
    H-89 dihydrochloride is a potent and selective inhibitor of protein kinase A (PKA) with an IC50 of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase.
    H-89 dihydrochloride
  • HY-D0815
    Propidium Iodide 25535-16-4 ≥98.0%
    Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.
    Propidium Iodide
  • HY-Y1890
    Cremophor EL 61791-12-6 99.52%
    Cremophor EL, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL is widely employed to improve dissolution and delivery of agents.
    Cremophor EL
  • HY-15559
    Hoechst 33342 23491-52-3 ≥98.0%
    Hoechst 33342 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution.
    Hoechst 33342
  • HY-Y0703
    Sodium carboxymethyl cellulose (Viscosity:800-1200 mPa.s) 9004-32-4 ≥98.0%
    Sodium carboxymethyl cellulose (Viscosity:800-1200 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.
    Sodium carboxymethyl cellulose (Viscosity:800-1200 mPa.s)
  • HY-D0843
    N-Ethylmaleimide 128-53-0 ≥98.0%
    N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC50 value of 6.3 μM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides.
    N-Ethylmaleimide
  • HY-15917
    DL-dithiothreitol 3483-12-3 ≥98.0%
    DL-dithiothreitol (DTT) is a reducing agent. DL-dithiothreitol forms a stable six-membered ring with an internal disulfide bond once oxidized.
    DL-dithiothreitol
Cat. No. Product Name / Synonyms Application Reactivity