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FITC-Dextran (MW 4000)

98 Cited Publications
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Based on 98 publication(s) in Google Scholar

FITC-Dextran (MW 4000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption.

For research use only. We do not sell to patients.

  • CAS No.: 60842-46-8
  • Molecular Weight:4000.00(Average)
  • Storage:

    4°C, protect from light

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

  • FITC-Dextran (MW 4000) Chemical Structure
    FITC-Dextran (MW 4000) Chemical Structure
  • Experimental Validation Results for FITC-Dextran (MW 4000)
  • Experimental Validation Results for FITC-Dextran (MW 4000)
  • Experimental Validation Results for FITC-Dextran (MW 4000)
  • Experimental Validation Results for FITC-Dextran (MW 4000)
  • Experimental Validation Results for FITC-Dextran (MW 4000)
  • Experimental Validation Results for FITC-Dextran (MW 4000)
  • Experimental Validation Results for FITC-Dextran (MW 4000)
  • Experimental Validation Results for FITC-Dextran (MW 4000)
  • Experimental Validation Results for FITC-Dextran (MW 4000)
  • Experimental Validation Results for FITC-Dextran (MW 4000)
CAS No.: 60842-46-8
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  • FITC-Dextran (MW 4000) Chemical Structure
    FITC-Dextran (MW 4000) Chemical Structure
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  • 1/16

    FITC-Dextran (MW 4000) purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2025 Apr 15;23(1):291. [Abstract]

    Customer Validation
     FITC-dextran (1 mg/mL; 45 min) permeability assay was performed to assess the barrier function of bEnd.3 endothelial cells.

  • 1/16

    FITC-Dextran (MW 4000) purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jul 18:e00741. [Abstract]

    Customer Validation
     Intestinal permeability was assessed by FITC‐Dextran (0.6 mg/g; Oral gavage) assays on day 10 after DSS initiation (n = 6).

  • 1/16

    FITC-Dextran (MW 4000) purchased from MedChemExpress. Usage Cited in: Cell Commun Signal. 2025 Jun 4;23(1):263. [Abstract]

    Customer Validation
     Quantitative analysis of FITC in serum collected from mice in the FITC-Dextran (MW 4000) (0.6 mg/g; Oral gavage; Single dose) intestinal permeability assay.

  • 1/16

    FITC-Dextran (MW 4000) purchased from MedChemExpress. Usage Cited in: Sci China Life Sci. 2025 Jul;68(7):2010-2027. [Abstract]

    Customer Validation
     Blood FITC-Dextran (MW 4000) (200 mg/kg; Oral gavage; Single dose) levels. The results showed that METTL3-deficient mice presented significantly increased serum FITC levels, indicating increased mucosal permeability.

  • 1/16

    FITC-Dextran (MW 4000) purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2025 Jun:312:144084. [Abstract]

    Customer Validation
     MFI variations with time in Ch1, Ch3 and Ch5 of 10 kDa FITC-dextran (0.1 mg/mL; 0-24 h) diffusion.

  • 1/16

    FITC-Dextran (MW 4000) purchased from MedChemExpress. Usage Cited in: Cancer Lett. 2024 Jun 1:591:216897. [Abstract]

    Customer Validation
     Fluorescence intensity of FITC-dextran (500 μg/mL; 36 h) in lower chamber of Transwell after incubation with TM-sEVs from patients with low relapse risk and high relapse risk in the upper chamber.

  • 1/16

    FITC-Dextran (MW 4000) purchased from MedChemExpress. Usage Cited in: Redox Rep. 2024 Dec;29(1):2433393. [Abstract]

    Customer Validation
     Intestinal permeability measured by serum fluorescein isothiocyanate FITC-Dextran (MW 4000) (0.44 mg/g; Oral gavage; Single dose) levels.

  • 1/16

    FITC-Dextran (MW 4000) purchased from MedChemExpress. Usage Cited in: Sci Adv. 2023 Oct 20;9(42):eadi0699. [Abstract]

    Customer Validation
     Ex vivo imaging showed biodistribution of FITC-Dextran (MW 4000) (500 μg/mouse; i.v.; Single dose).

  • 1/16

    FITC-Dextran (MW 4000) purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2021 Oct;8(20):e2101912. [Abstract]

    Customer Validation
     Large particle transport assays through µE‐BBB were conducted by passing of FITC‐dextran (100 µg/mL; 1 h) solution through the lumen compartment of the system and quantifying the amount of FITC‐dextran that had accumulated in the basolateral compartment.

  • 1/16

    FITC-Dextran (MW 4000) purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2021 Oct;8(20):e2101912. [Abstract]

    Customer Validation
     To evaluate the effect of erythrocytes on the permeability of the BBB, isolated erythrocytes from young or old mice, supplemented with FITC‐dextran (100 μg/mL; 1 h), were circulated through the µE‐BBB.

  • FITC-Dextran (MW 4000)