1. Recombinant Proteins
  2. Enzymes & Regulators
  3. Protease Inhibitors
  4. Tissue Inhibitor of Metalloproteinase (TIMPs)

Tissue Inhibitor of Metalloproteinase (TIMPs)

Cat. No. Product Name / Synonyms Species Source
  • HY-P71117
    TIMP-2 Protein, Human (HEK293, His)

    Metalloproteinase Inhibitor 2; CSC-21K; Tissue Inhibitor of Metalloproteinases 2; TIMP-2; TIMP2

    Human HEK293
    TIMP-2 protein is a tissue inhibitor of metalloproteinases that can bind and inactivate various metalloproteinases, including collagenases, such as MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9 , MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. It interacts with MMP2 through its C-terminal region, specifically targets the C-terminal PEX domain and inhibits MMP2 activity. TIMP-2 Protein, Human (HEK293, His) is the recombinant human-derived TIMP-2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TIMP-2 Protein, Human (HEK293, His) is 194 a.a., with molecular weight of 23-26 kDa.
  • HY-P73441
    TIMP-1 Protein, Rat (HEK293)

    Metalloproteinase Inhibitor 1; EPA; TIMP-1; CLGI; TIMP

    Rat HEK293
    The IgG3 Fc protein is the constant region of an immunoglobulin heavy chain that acts as a receptor for a specific antigen. TIMP-1 Protein, Rat (HEK293) is the recombinant rat-derived TIMP-1 protein, expressed by HEK293 , with tag free. The total length of TIMP-1 Protein, Rat (HEK293) is 194 a.a., with molecular weight of ~28 kDa.
  • HY-P73442
    TIMP-2 Protein, Human (HEK293)

    TIMP-2; Metalloproteinase inhibitor 2; CSC-21K; TIMP2

    Human HEK293
    TIMP-2 protein is a tissue inhibitor of metalloproteinases that can bind and inactivate various metalloproteinases, including collagenases, such as MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9 , MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. It interacts with MMP2 through its C-terminal region, specifically targets the C-terminal PEX domain and inhibits MMP2 activity. TIMP-2 Protein, Human (HEK293) is the recombinant human-derived TIMP-2 protein, expressed by HEK293 , with tag free. The total length of TIMP-2 Protein, Human (HEK293) is 194 a.a., with molecular weight of ~20 kDa.
  • HY-P73597
    TIMP-1 Protein, Human (HEK293)

    Metalloproteinase Inhibitor 1; EPA; TIMP-1; CLGI; TIMP

    Human HEK293
    The TIMP-1 protein forms a one-to-one complex with the target metalloprotease, irreversibly inactivating it by binding to the catalytic zinc cofactor. It inhibits multiple MMPs, activates cell signaling through CD63 and ITGB1, and interacts with MMP1, MMP3, MMP10, and MMP13. TIMP-1 Protein, Human (HEK293) is the recombinant human-derived TIMP-1 protein, expressed by HEK293 , with tag free. The total length of TIMP-1 Protein, Human (HEK293) is 184 a.a., with molecular weight of ~26 kDa.
  • HY-P71110
    TIMP-1 Protein, Mouse (HEK293)

    Metalloproteinase Inhibitor 1; Erythroid-Potentiating Activity; EPA; Fibroblast collagenase Inhibitor; Collagenase Inhibitor; Tissue Inhibitor of Metalloproteinases 1; TIMP-1; TIMP1; CLGI; TIMP

    Mouse HEK293
    TIMP-1 is a metalloproteinase inhibitor that irreversibly inactivates collagenase and other metalloproteinases by binding to their catalytic zinc cofactor. It regulates MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16 and affects cellular processes such as differentiation, migration and cell death. TIMP-1 Protein, Mouse (HEK293) is the recombinant mouse-derived TIMP-1 protein, expressed by HEK293 , with tag free. The total length of TIMP-1 Protein, Mouse (HEK293) is 181 a.a., with molecular weight of ~26.0 kDa.
  • HY-P71137
    TIMP-2 Protein, Mouse (HEK293, His)

    TIMP-2; CSC-21Ktissue inhibitor of metalloproteinase 2; metalloproteinase inhibitor 2; TIMP metalloproteinase inhibitor 2; Tissue inhibitor of metalloproteinase 2.

    Mouse HEK293
    TIMP-2 is a tissue inhibitor of metalloproteinases that forms complexes with metalloproteinases, especially collagenases, effectively and irreversibly inactivating them by binding to their catalytic zinc cofactor. This interaction plays a crucial role in regulating the activity of metalloproteinases. TIMP-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived TIMP-2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TIMP-2 Protein, Mouse (HEK293, His) is 194 a.a., with molecular weight of 21-23 kDa.
  • HY-P71055
    TIMP-1 Protein, Human (184a.a, HEK293, His)

    Metalloproteinase Inhibitor 1; Erythroid-Potentiating Activity; EPA; Fibroblast collagenase Inhibitor; Collagenase Inhibitor; Tissue Inhibitor of Metalloproteinases 1; TIMP-1; TIMP1; CLGI; TIMP

    Human HEK293
    The TIMP-1 protein forms a one-to-one complex with the target metalloprotease, irreversibly inactivating it by binding to the catalytic zinc cofactor. It inhibits multiple MMPs, activates cell signaling through CD63 and ITGB1, and interacts with MMP1, MMP3, MMP10, and MMP13. TIMP-1 Protein, Human (184a.a, HEK293, His) is the recombinant human-derived TIMP-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of TIMP-1 Protein, Human (184a.a, HEK293, His) is 184 a.a., with molecular weight of ~27.0 kDa.
  • HY-P71368
    TIMP-4 Protein, Human (HEK293, His)

    Metalloproteinase inhibitor 4; TIMP-4; Tissue inhibitor of metalloproteinases 4; TIMP4

    Human HEK293
    TIMP-4, a member of the tissue inhibitor of metalloproteinases family, forms complexes with metalloproteinases, including collagenases, and exerts irreversible inactivation by binding to their catalytic zinc cofactor. Its inhibitory effect is recognized on a range of metalloproteases, particularly MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9. TIMP-4 Protein, Human (HEK293, His) is the recombinant human-derived TIMP-4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TIMP-4 Protein, Human (HEK293, His) is 195 a.a., with molecular weight of ~24.0 kDa.
  • HY-P71137A
    TIMP-2 Protein, Mouse (HEK293, C-His)

    TIMP-2; CSC-21Ktissue inhibitor of metalloproteinase 2; metalloproteinase inhibitor 2; TIMP metalloproteinase inhibitor 2; Tissue inhibitor of metalloproteinase 2.

    Mouse HEK293
    TIMP-2 is a tissue inhibitor of metalloproteinases that forms complexes with metalloproteinases, especially collagenases, effectively and irreversibly inactivating them by binding to their catalytic zinc cofactor. This interaction plays a crucial role in regulating the activity of metalloproteinases. TIMP-2 Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived TIMP-2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TIMP-2 Protein, Mouse (HEK293, C-His) is 194 a.a., with molecular weight of ~21.41 kDa.
  • HY-P73596
    TIMP-1 Protein, Human (HEK293, Fc)

    Metalloproteinase Inhibitor 1; EPA; TIMP-1; CLGI; TIMP

    Human HEK293
    The TIMP-1 protein forms a one-to-one complex with the target metalloprotease, irreversibly inactivating it by binding to the catalytic zinc cofactor. It inhibits multiple MMPs, activates cell signaling through CD63 and ITGB1, and interacts with MMP1, MMP3, MMP10, and MMP13. TIMP-1 Protein, Human (HEK293, Fc) is the recombinant human-derived TIMP-1 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of TIMP-1 Protein, Human (HEK293, Fc) is 184 a.a., with molecular weight of ~49.1 kDa.
Cat. No. Product Name Effect Purity