1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. MMP
  4. MMP-3 Inhibitors

MMP-3 Inhibitors

MMP-1

MMP-2

MMP-3

MMP-8

MMP-9

MMP-13

MMP-14

MMP-7

MMP-12

MMP-10

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Sorry. There is currently no product that acts on isoform MMP-3 together.

Please try each isoform separately.

MMP-3 Specific Inhibitors
Product Name MMP-3 MMP-1 MMP-2 MMP-8 MMP-9 MMP-13 MMP-14 MMP-7 MMP-12 MMP-3 Selectivity Purity
UK 356618
MMP-3, IC50: 5.9 nM
MMP-1, IC50: 51 μM
MMP-2, IC50: 1.79 μM
 
MMP-9, IC50: 0.84 μM
MMP-13, IC50: 73 nM
MMP-14, IC50: 1.9 μM
    Selective Inhibitor >98.0%
Luteolin 7-O-glucuronide
MMP-3, IC50: 7.99 μM
MMP-1, IC50: 17.63 μM
 
MMP-8, IC50: 11.42 μM
MMP-9, IC50: 12.85 μM
MMP13, IC50: 0.03 μM
      Selective Inhibitor 99.31%
Apigenin-7-glucuronide
MMP-3, IC50: 12.87 μM
   
MMP-8, IC50: 22.39 μM
MMP-9, IC50: 17.52 μM
MMP13, IC50: 0.27 μM
      Selective Inhibitor 98.83%
UK-370106
MMP-3, IC50: 23 nM
 
MMP-2, IC50: 34.2 μM
MMP-8, IC50: 1.75 μM
MMP-9, IC50: 30.4 μM
MMP-13, IC50: 2.3 μM
MMP-14, IC50: 66.9 μM
MMP-7, IC50: 5.8 μM
MMP-12, IC50: 42 nM
Selective Inhibitor >99.0%
MMP3 inhibitor 1
MMP-3, IC50: 1 nM
MMP-1, IC50: 14000 nM
MMP-2, IC50: 529 nM
 
MMP-9, IC50: 2420 nM
 
MMP-14, IC50: 20100 nM
    Selective Inhibitor
Ilomastat
MMP-3, IC50: 1.9 nM
Fibroblast collagenase, Ki: 0.4 nM (Human skin)
MMP-1, IC50: 1.5 nM
MMP-2, IC50: 1.1 nM
 
MMP-9, IC50: 0.5 nM
        Pan Inhibitor 98.48%
PF-00356231 hydrochloride
MMP-3, IC50: 0.39 μM
   
MMP-8, IC50: 1.7 μM
MMP-9, IC50: 0.98 μM
MMP13, IC50: 0.65 nM
   
MMP-12, IC50: 1.4 μM
Pan Inhibitor >99.0%
Marimastat
MMP-3, IC50: 3 nM
MMP-1, IC50: 5 nM
MMP-2, IC50: 6 nM
     
MMP-14, IC50: 9 nM
MMP-7, IC50: 13 nM
  Pan Inhibitor >98.0%
Cordycepin
MMP-3
MMP-1
              Pan Inhibitor >99.0%
Prinomastat
MMP-3, IC50: 6..3 nM
MMP-3, Ki: 0.3 nM
MMP-1, IC50: 79 nM
MMP-2, Ki: 0.05 nM
 
MMP-9, IC50: 5 nM
MMP-9, Ki: 0.26 nM
        Pan Inhibitor 95.03%
XL-784
MMP-3, IC50: 120 nM
MMP-1, IC50: 1900 nM
MMP-2, IC50: 0.81 nM
MMP-8, IC50: 10.8 nM
MMP-9, IC50: 18 nM
MMP13, IC50: 0.56 nM
      Pan Inhibitor 98.20%
ARP-100
MMP-3, IC50: 4.5 μM
MMP-1, IC50: >50 μM
MMP-2, IC50: 12 nM
 
MMP-9, IC50: 0.2 μM
   
MMP-7, IC50: >50 μM
  Pan Inhibitor >99.0%
Tanomastat
MMP-3, Ki: 143 nM
 
MMP-2, Ki: 11 nM
 
MMP-9, Ki: 301 nM
MMP-13, Ki: 1470 nM
      Pan Inhibitor >99.0%
Cipemastat
stromelysins 1, Ki: 527 nM
collagenases 1, Ki: 3.0 nM
gelatinase A, Ki: 154 nM
collagenases 2, Ki: 4.4 nM
gelatinase B, Ki: 59.1 nM
collagenases 3, Ki: 3.4 nM
      Pan Inhibitor
XL-784 free base
MMP-3, IC50: 120 nM
MMP-1, IC50: 1900 nM
MMP-2, IC50: 0.81 nM
MMP-8, IC50: 10.8 nM
MMP-9, IC50: 18 nM
MMP-13, IC50: 0.56 nM
      Pan Inhibitor