MMP-7-IN-2
Based on 1 Customer Validation
MMP-7-IN-2 is a potent and selective inhibitor of MMP7 with an IC50 value of 16 nM. MMP-7-IN-2 can be used for the research of diseases such as cancer and fibrosis.
For research use only. We do not sell to patients.
- Purity: 99.08%
- CAS No.: 2848717-49-5
- Formula: C28H40ClF3N6O9S
- Molecular Weight:729.17
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Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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MMP-7 16 nM (IC50) |
MMP-14 11000 nM (IC50) |
MMP-12 12000 nM (IC50) |
MMP-2 33000 nM (IC50) |
MMP-3 >100000 nM (IC50) |
MMP-8 >100000 nM (IC50) |
MMP-9 >100000 nM (IC50) |
MMP-13 >100000 nM (IC50) |
MMP-1 ＞100000 nM (IC50) |
MMP-7-IN-2 (compound 16) (1-5 μM; 15 min-4 h) exhibits good stability in serum and liver microsomes without significant degradation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2848717-49-5
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Appearance Solid
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Molecular Weight 729.17
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Formula C28H40ClF3N6O9S
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Color White to off-white
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (137.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3714 mL | 6.8571 mL | 13.7142 mL | 34.2856 mL |
| 5 mM | 0.2743 mL | 1.3714 mL | 2.7428 mL | 6.8571 mL | |
| 10 mM | 0.1371 mL | 0.6857 mL | 1.3714 mL | 3.4286 mL | |
| 15 mM | 0.0914 mL | 0.4571 mL | 0.9143 mL | 2.2857 mL | |
| 20 mM | 0.0686 mL | 0.3429 mL | 0.6857 mL | 1.7143 mL | |
| 25 mM | 0.0549 mL | 0.2743 mL | 0.5486 mL | 1.3714 mL | |
| 30 mM | 0.0457 mL | 0.2286 mL | 0.4571 mL | 1.1429 mL | |
| 40 mM | 0.0343 mL | 0.1714 mL | 0.3429 mL | 0.8571 mL | |
| 50 mM | 0.0274 mL | 0.1371 mL | 0.2743 mL | 0.6857 mL | |
| 60 mM | 0.0229 mL | 0.1143 mL | 0.2286 mL | 0.5714 mL | |
| 80 mM | 0.0171 mL | 0.0857 mL | 0.1714 mL | 0.4286 mL | |
| 100 mM | 0.0137 mL | 0.0686 mL | 0.1371 mL | 0.3429 mL |
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