1. Metabolic Enzyme/Protease
  2. MMP
  3. MMP-7-IN-2

MMP-7-IN-2 (compound 16) is a selective inhibitor of MMP7 with an IC50 value of 16 nM.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

MMP-7-IN-2 Chemical Structure

MMP-7-IN-2 Chemical Structure

CAS No. : 2848717-49-5

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5 mg USD 750 In-stock
10 mg USD 1350 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

MMP-7-IN-2 (compound 16) is a selective inhibitor of MMP7 with an IC50 value of 16 nM[1].

IC50 & Target[1].

MMP-7

16 nM (IC50)

MMP-14

11000 nM (IC50)

MMP-12

12000 nM (IC50)

MMP-2

33000 (IC50)

MMP-3

>100000 (IC50)

MMP-8

>100000 (IC50)

MMP-9

>100000 (IC50)

MMP-13

>100000 (IC50)

Molecular Weight

729.17

Formula

C28H40ClF3N6O9S

CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (137.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3714 mL 6.8571 mL 13.7142 mL
5 mM 0.2743 mL 1.3714 mL 2.7428 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3714 mL 6.8571 mL 13.7142 mL 34.2856 mL
5 mM 0.2743 mL 1.3714 mL 2.7428 mL 6.8571 mL
10 mM 0.1371 mL 0.6857 mL 1.3714 mL 3.4286 mL
15 mM 0.0914 mL 0.4571 mL 0.9143 mL 2.2857 mL
20 mM 0.0686 mL 0.3429 mL 0.6857 mL 1.7143 mL
25 mM 0.0549 mL 0.2743 mL 0.5486 mL 1.3714 mL
30 mM 0.0457 mL 0.2286 mL 0.4571 mL 1.1429 mL
40 mM 0.0343 mL 0.1714 mL 0.3429 mL 0.8571 mL
50 mM 0.0274 mL 0.1371 mL 0.2743 mL 0.6857 mL
60 mM 0.0229 mL 0.1143 mL 0.2286 mL 0.5714 mL
80 mM 0.0171 mL 0.0857 mL 0.1714 mL 0.4286 mL
100 mM 0.0137 mL 0.0686 mL 0.1371 mL 0.3429 mL
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MMP-7-IN-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
MMP-7-IN-2
Cat. No.:
HY-153563
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