1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. MMP
  4. MMP-2 Inhibitors

MMP-2 Inhibitors

MMP-1

MMP-2

MMP-3

MMP-8

MMP-9

MMP-13

MMP-14

MMP-7

MMP-12

MMP-10

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Sorry. There is currently no product that acts on isoform MMP-2 together.

Please try each isoform separately.

MMP-2 Specific Inhibitors
Product Name MMP-2 MMP-1 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 MMP-7 MMP-12 MMP-10 MMP-2 Selectivity Purity
SB-3CT
MMP-2, Ki: 13.9 nM
     
MMP-9, Ki: 600 nM
          Selective Inhibitor 99.32%
Auraptene
MMP-2
                  Selective Inhibitor 99.03%
ARP-100
MMP-2, IC50: 12 nM
MMP-1, IC50: >50 μM
MMP-3, IC50: 4.5 μM
 
MMP-9, IC50: 0.2 μM
   
MMP-7, IC50: >50 μM
    Selective Inhibitor >99.0%
Tanomastat
MMP-2, Ki: 11 nM
 
MMP-3, Ki: 143 nM
 
MMP-9, Ki: 301 nM
MMP-13, Ki: 1470 nM
        Selective Inhibitor >99.0%
Ilomastat
MMP-2, IC50: 1.1 nM
Fibroblast collagenase, Ki: 0.4 nM (Human skin)
MMP-1, IC50: 1.5 nM
MMP-3, IC50: 1.9 nM
 
MMP-9, IC50: 0.5 nM
          Pan Inhibitor 98.48%
Astragaloside IV
MMP-2
     
MMP-9
          Pan Inhibitor >98.0%
Marimastat
MMP-2, IC50: 6 nM
MMP-1, IC50: 5 nM
MMP-3, IC50: 3 nM
     
MMP-14, IC50: 9 nM
MMP-7, IC50: 13 nM
    Pan Inhibitor >98.00%
Prinomastat
MMP-2, Ki: 0.05 nM
MMP-1, IC50: 79 nM
MMP-3, IC50: 6..3 nM
MMP-3, Ki: 0.3 nM
 
MMP-9, IC50: 5 nM
MMP-9, Ki: 0.26 nM
          Pan Inhibitor 95.03%
Morroniside
MMP2
     
MMP9
          Pan Inhibitor >98.0%
UK 356618
MMP-2, IC50: 1.79 μM
MMP-1, IC50: 51 μM
MMP-3, IC50: 5.9 nM
 
MMP-9, IC50: 0.84 μM
MMP-13, IC50: 73 nM
MMP-14, IC50: 1.9 μM
      Pan Inhibitor >98.0%
XL-784
MMP-2, IC50: 0.81 nM
MMP-1, IC50: 1900 nM
MMP-3, IC50: 120 nM
MMP-8, IC50: 10.8 nM
MMP-9, IC50: 18 nM
MMP13, IC50: 0.56 nM
        Pan Inhibitor 98.20%
UK-370106
MMP-2, IC50: 34.2 μM
 
MMP-3, IC50: 23 nM
MMP-8, IC50: 1.75 μM
MMP-9, IC50: 30.4 μM
MMP-13, IC50: 2.3 μM
MMP-14, IC50: 66.9 μM
MMP-7, IC50: 5.8 μM
MMP-12, IC50: 42 nM
  Pan Inhibitor >99.0%
Prinomastat hydrochloride
MMP-2, Ki: 0.05 nM
MMP-1, IC50: 79 nM
   
MMP-9, IC50: 5 nM
MMP-9, Ki: 0.26 nM
MMP-13, IC50: 6.3 nM
MMP-13, Ki: 0.3 nM
        Pan Inhibitor >95.0%
MMP13-IN-3
MMP-2, IC50: 18 μM
     
MMP-9, IC50: 8.9 μM
MMP-13, IC50: 1 nM
MMP-14, IC50: 8.3 μM
   
MMP-10, IC50: 16 μM
Pan Inhibitor
MMP3 inhibitor 1
MMP-2, IC50: 529 nM
MMP-1, IC50: 14000 nM
MMP-3, IC50: 1 nM
 
MMP-9, IC50: 2420 nM
 
MMP-14, IC50: 20100 nM
      Pan Inhibitor
BR351
MMP-2, IC50: 4 nM
   
MMP-8, IC50: 2 nM
MMP-9, IC50: 11 nM
MMP13, IC50: 50 nM
        Pan Inhibitor
Cipemastat
gelatinase A, Ki: 154 nM
collagenases 1, Ki: 3.0 nM
stromelysins 1, Ki: 527 nM
collagenases 2, Ki: 4.4 nM
gelatinase B, Ki: 59.1 nM
collagenases 3, Ki: 3.4 nM
        Pan Inhibitor
XL-784 free base
MMP-2, IC50: 0.81 nM
MMP-1, IC50: 1900 nM
MMP-3, IC50: 120 nM
MMP-8, IC50: 10.8 nM
MMP-9, IC50: 18 nM
MMP-13, IC50: 0.56 nM
        Pan Inhibitor
CTTHWGFTLC, CYCLIC
MMP-2
     
MMP-9
          Pan Inhibitor