495-02-3
495-02-3
Chemical Structure
Auraptene
- CAS No.: 495-02-3
- Formula:C19H22O3
- Molecular Weight:298.38
IUPAC Name: (E)-7-((3,7-dimethylocta-2,6-dien-1-yl)oxy)-2H-chromen-2-one
InChIKey: RSDDHGSKLOSQFK-RVDMUPIBSA-N
SMILES: O=C1C=CC2=CC=C(OC/C=C(C)/CC/C=C(C)/C)C=C2O1
Biological Activity: Auraptene is an orally active geranyloxycoumarin that can be isolated from plants in the Brassicaceae family, antibacterial, anti-pathogen, antioxidant, anti-tumor, and neuroprotective effects. Auraptene plays an important role in the treatment of various chronic diseases such as hypertension and cystic fibrosis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Auraptene | 99.97% | Auraptene is an orally active geranyloxycoumarin that can be isolated from plants in the Brassicaceae family, antibacterial, anti-pathogen, antioxidant, anti-tumor, and neuroprotective effects. Auraptene plays an important role in the treatment of various chronic diseases such as hypertension and cystic fibrosis. | ||||||||||||||||||||
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Auraptene (Standard) | ≥98% | Auraptene (Standard) is the analytical standard of Auraptene. This product is intended for research and analytical applications. Auraptene is an orally active geranyloxycoumarin that can be isolated from plants in the Brassicaceae family, antibacterial, anti-pathogen, antioxidant, anti-tumor, and neuroprotective effects. Auraptene plays an important role in the treatment of various chronic diseases such as hypertension and cystic fibrosis. | ||||||||||||||||||||
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Umbelliprenin | 98.83% | Umbelliprenin, a prenylated coumarin, is an antioxidant with anticancer, anti-inflammatory and immunomodulatory effects. Umbelliprenin inhibits lipoxygenase managing the inflammation pathways. In inflammatory macrophages, Umbelliprenin suppresses nitric oxide production as well as inducible nitric oxide synthase (NO synthase). | ||||||||||||||||||||
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7-(6'R-Hydroxy-3',7'-dimethylocta-2',7'-dienyloxy)coumarin | 7-(6'R-Hydroxy-3',7'-dimethylocta-2',7'-dienyloxy)coumarin is a natural product. | |||||||||||||||||||||
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Neuroinflammatory-IN-1 | Neuroinflammatory-IN-1 (Compound 5) is an anti-neuroinflammatory agent and displays inhibitory effect on nitric oxide (NO) production with an IC50 value of 65.4 μM. | |||||||||||||||||||||
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Anisocoumarin H | 96% | Anisocoumarin H is a coumarin that exhibits antifungal activity. Anisocoumarin H shows the activities against Microsporum gypseum, Trichophyton rubrum and Trichophyton mentagrophytes with MICs of 62.5 µg/mL. | ||||||||||||||||||||
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8-Demethoxyschinilenol | 98.0% | 8-Demethoxyschinilenol is a terpenoid coumarin. 8-Demethoxyschinilenol can be isolated from the leaves of Zanthoxylum schinifolium. 8-Demethoxyschinilenol exhibits moderate inhibitory activity against α-glucosidase, with an IC50 of 164.4 μM. | ||||||||||||||||||||
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7-Geranyloxy-5-methoxycoumarin | 7-Geranyloxy-5-methoxycoumarin is a natural geranyloxycoumarin found in the twigs of Toddalia asiatica. | |||||||||||||||||||||
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7-O-Geranylscopoletin | 97.0% | 7-O-Geranylscopoletin is a coumarin from the root of Atalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as chronic rheumatism, paralysis, antispasmodic, stimulant and hemiplegia. | ||||||||||||||||||||
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Marmin | 99.40% | Marmin is a histamine receptor inhibitor and tracheal smooth muscle relaxant. Marmin antagonizes histamine- and methacholine-induced contraction of tracheal smooth muscle. Marmin inhibits histamine release from mast cells, and also blocks extracellular calcium influx via voltage-dependent calcium channels as well as calcium release from intracellular calcium stores, thereby effectively inhibiting calcium-mediated smooth muscle contraction. Marmin slightly enhances the relaxant effect of isoprenaline, and induces epithelial-dependent tracheal smooth muscle relaxation independent of nitric oxide, cGMP or β2-adrenergic pathways through the release of prostaglandin E2. | ||||||||||||||||||||
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7-Prenyloxycoumarin | 99.89% | 7-Prenyloxycoumarin (7-O-Prenylumbelliferone) is a secondary metabolite from the endophytic fungus of Annulohypoxylon ilanense. | ||||||||||||||||||||
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5-Geranoxy-7-methoxycoumarin | 98.24% | 5-Geranoxy-7-methoxycoumarin is a coumarin with anti-cancer, antifungal, and ?antibacterial?activities. 5-Geranoxy-7-methoxycoumarin induces cell apoptosis. | ||||||||||||||||||||
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References
- [1]. La VD, et al. Anti-inflammatory and wound healing potential of citrus auraptene. J Med Food. 2013 Oct;16(10):961-4. [Content Brief]
- [2]. Krishnan P, et al. Effects of Auraptene on IGF-1 Stimulated Cell Cycle Progression in the Human Breast Cancer Cell Line, MCF-7. Int J Breast Cancer. 2012;2012:502092. [Content Brief]
