2. Anti-infection
  3. Bacterial Fungal
  4. 5-Geranoxy-7-methoxycoumarin

5-Geranoxy-7-methoxycoumarin is a coumarin with anti-cancer, antifungal, and  antibacterial activities. 5-Geranoxy-7-methoxycoumarin induces cell apoptosis.

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5-Geranoxy-7-methoxycoumarin Chemical Structure

5-Geranoxy-7-methoxycoumarin Chemical Structure

CAS No. : 7380-39-4

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5-Geranoxy-7-methoxycoumarin Related Antibodies

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Description

5-Geranoxy-7-methoxycoumarin is a coumarin with anti-cancer, antifungal, and  antibacterial activities. 5-Geranoxy-7-methoxycoumarin induces cell apoptosis[1][2].

In Vitro

5-Geranoxy-7-methoxycoumarin (12.5-200 µM; 24-72 hours) induces a significant inhibition of cell growth in a time-dependent manner in SW480 cells[1].
5-Geranoxy-7-methoxycoumarin (50 µM;48 hours) promotes DNA fragmentation and causes apoptosis through inhibition of the p38 MAPK signaling pathway in SW480 cells[1].
5-Geranoxy-7-methoxycoumarin (50 µM; 24-48 hours) increases the percentage of cells in the sub G1/G0 phase from 5.3% (in control cells) to 18% after 48 h incubation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

5-Geranoxy-7-methoxycoumarin Related Antibodies

Cell Proliferation Assay[1]

Cell Line: SW480
Concentration: 0-20 μM
Incubation Time: 24, 48 and 72 hours
Result: Inhibited cell growth by 67% at 72 hours.

Apoptosis Analysis[1]

Cell Line: SW480 cells
Concentration: 50 μM
Incubation Time: 48 hours
Result: Induced cell apoptosis.

Cell Cycle Analysis[1]

Cell Line: SW480 cells
Concentration: 50 μM
Incubation Time: 48 hours
Result: Inhibited cell cycle progression in vitro.
Molecular Weight

328.40

Formula

C20H24O4
CAS No.
SMILES

O=C1OC2=C(C(OC/C=C(CC/C=C(C)/C)\C)=CC(OC)=C2)C=C1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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5-Geranoxy-7-methoxycoumarin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Geranoxy-7-methoxycoumarin7380-39-4BacterialFungalApoptosisDNA fragmentationantifungalbacterialInhibitorinhibitorinhibit

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