Basement Membrane Matrix HC

Basement membrane matrix is a natural basement membrane preparation extracted from mouse tumor tissue rich in extracellular matrix (ECM) proteins. It can mimic the in vivo cellular growth microenvironment and provide structural support for cells. It contains abundant extracellular matrix components, including laminin, type IV collagen (Collagen IV), entactin, and heparan sulfate proteoglycans (HSPGs). It also contains a variety of naturally occurring growth factors, including insulin-like growth factor-1 (IGF-1), transforming growth factor-β (TGF-β), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), and basic fibroblast growth factor (bFGF).

MCE High-Concentration Basement Membrane Matrix has a higher protein concentration and greater gel strength than standard basement membrane matrix, providing a more stable three-dimensional supporting structure. It is suitable for the establishment of in vivo models and provides cells with a microenvironment that more closely resembles physiological conditions for cell growth, differentiation, and tissue formation, thereby enabling more accurate simulation of in vivo conditions and improving the physiological relevance and reliability of experimental results. The phenol red-free formulation can effectively minimize potential interference from phenol red and is suitable for experiments that are sensitive to background signals or require reduced color interference.