Basement Membrane Matrix HC
Based on 2 publication(s) in Google Scholar
MCE Basement Membrane Matrix HC (High Concentration) is primarily composed of natural basement membrane matrix extracted from mouse tumors, with higher content of various cytokines than the standard type.This product is mainly used for angiogenesis experiments, construction of animal models and 3D tumor models.
-
Storage :
-20°C, 2 years.
Avoid repeated freezing and thawing.
Shipping with dry ice
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Description & Advantages
MCE Basement Membrane Matrix HC (High Concentration) is a natural basement membrane matrix extracted from mouse tumors and is composed mainly of various growth factors and extracellular matrix components. The main extracellular matrix components are: Laminin, Col-IV, Entactin, Heparan sulphate proteoglycans, etc. The main growth factor components are: insulin-like growth factor (IGF-1), transforming growth factor beta (TGF-β), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), fibroblast growth factor (bFGF), etc. The percentage of each of these growth factors is higher than that of standard basement membrane matrix.
MCE Basement Membrane Matrix HC (High Concentration) is mainly used for angiogenesis experiments, animal models and 3D tumor model construction.
Protocol
a. Use a pre-cooled pipette to blow the matrix gel evenly after thawing.
b. Dilute MCE Basement Membrane Matrix HC with cell suspension at 4°C in a 1:1 ratio to a suitable final concentration.
c. Inject diluted cell suspension at a depth of 1 cm under the skin on nude mice. The cell suspension should be injected in 30 minutes and be placed on ice to slow down apoptosis and prevent from gelling.
d. Formed tumors can be seen in about 1 week.
Note: When thawing the product for the first time, immerse the vial in crushed ice and place it in a 4°C to melt. After melting, mix thoroughly before aliquoting, and then store at -20°C.
Publications
-
Journal Impact Factor
-
Most Recent
-
Cancer Biol MedVAMP2/SNAP25 promotes the aggressive progression of head and neck cancer by regulating the fate of multivesicular bodies. [Abstract]2026 May 12:j.issn.2095-3941.2025.0522. PMID: 42125990
Storage
-20°C, 2 years.
Avoid repeated freezing and thawing.
Shipping with dry ice
Components
| Components | HY-K6008-1 mL | HY-K6008-5 mL | HY-K6008-10 mL |
|---|---|---|---|
| Basement Membrane Matrix HC | 1 mL | 5 mL | 10 mL |
Please enter the correct Lot Number
