2. 生化学アッセイ試薬
  3. Drug Delivery

Drug Delivery

Targeted Delivery Across Biological Barriers Prolonged Circulation Controlled Release

Drug Delivery systems (DDS) can deliver drugs to the target location at the right time, improving drug bioavailability while reducing drug toxicity.

MCE offers 1000+ drug delivery reagents, including multiple lipids, functionalized PEG, polymers, and lipid nanoparticles.

Drug Delivery (2650):

製品番号 製品名 CAS 番号 純度 構造式
  • HY-134541
    SM-102 2089251-47-6 99.97%
    SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines.
    SM-102
  • HY-112735
    Hexadimethrine bromide

    Polybrene

    		28728-55-4 99.69%
    Hexadimethrine bromide (Polybrene) is a cationic polymer used routinely to enhance the efficiency of retrovirus vector-mediated gene transfer.
    Hexadimethrine bromide
  • HY-112251
    D-Lin-MC3-DMA 1224606-06-7 99.91%
    D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
    D-Lin-MC3-DMA
  • HY-W040193
    DSPC

    DSPC

    		816-94-4 99.95%
    DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system.
    DSPC
  • HY-112764
    mPEG2000-DMG

    DMG-PEG 2000

    		160743-62-4 98.40%
    DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles.
    mPEG2000-DMG
  • HY-182100A
    DSPE-PEG2000-MTP
    DSPE-PEG2000-MTP is a PEG compound which composed of DSPE and a muscle-targeting peptide (MTP). MTP is a muscle-targeting peptide with the property of targeting muscle tissue. DSPE-PEG2000-MTP can be used for drug delivery.
    DSPE-PEG2000-MTP
  • HY-182095A
    DSPE-PEG2000-CTP
    DSPE-PEG2000-CTP is a PEG compound which composed of DSPE and a Cardiac-targeting peptide CTP (HY-P4094). CTP molecules that specifically recognize cardiac tissue and is primarily used for targeted drug delivery. CTP effectively recognizes and binds to specific receptors on the surface of cardiac cells, thereby achieving precise localization of drug molecules. DSPE-PEG2000-CTP can be used for drug delivery.
    DSPE-PEG2000-CTP
  • HY-182101A
    DSPE-PEG2000-VHPKQHRGGSKGC
    DSPE-PEG2000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a muscle-targeting peptide VHPKQHRGGSKGC (HY-P11088). GNYTCEVTELTREGETIIELK is a peptide that can bind to VCAM1. DSPE-PEG2000-GNYTCEVTELTREGETIIELK can be used for drug delivery.
    DSPE-PEG2000-VHPKQHRGGSKGC
  • HY-138170
    ALC-0315 2036272-55-4 99.90%
    ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine.
    ALC-0315
  • HY-112005
    DOPE

    DOPE

    		4004-05-1 99.96%
    DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA.
    DOPE
  • HY-N0322A
    Cholesterol (Water Soluble) 98.0%
    Cholesterol Water Soluble is a major sterol in mammals, constituting 20-25% of the structural composition of the plasma membrane. The plasma membrane is highly permeable to water but relatively impermeable to ions and protons. Cholesterol Water Soluble plays an important role in determining the fluidity and permeability characteristics of membranes and the function of transporters and signaling proteins. Cholesterol Water Soluble is also an endogenous estrogen-related receptor alpha (ERRα) agonist. Cholesterol Water Soluble can be used to study the effects of cholesterol on potassium currents in inner hair cells.
    (Note: This product is a mixture of Cholesterol and Methyl-β-cyclodextrin. The product specifications below only indicate the effective content of Cholesterol.)
    Cholesterol (Water Soluble)
  • HY-112754A
    DOTAP chloride

    DOTAP (chloride)

    		132172-61-3 99.91%
    DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid.
    DOTAP chloride
  • HY-142979
    DSPE-PEG 2000 892144-24-0 99.95%
    DSPE-PEG 2000 is a PEG polymer containing DSPE and amine end groups. DSPE-PEG 2000 can be used to form micelles as nanoparticles for drug delivery.
    DSPE-PEG 2000
  • HY-B2247
    PLGA (50:50) 34346-01-5 99.41%
    PLGA (50:50) (poly(lactic-co-glycolic acid) (50:50)) is a copolymer of poly lactic acid (PLA) and poly glycolic acid (PGA) which can be used to fabricate devices for drug delivery and tissue engineering applications.
    PLGA (50:50)
  • HY-140739
    DSPE-PEG2000-Maleimide sodium (purity>95%) 99.58%
    DSPE-PEG2000-Maleimide sodium (purity>95%) is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide sodium (purity>95%) can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration.
    DSPE-PEG2000-Maleimide sodium (purity>95%)
  • HY-B0633A
    Hyaluronic acid 9004-61-9
    Hyaluronic acid is a biopolymer composed of repeating units of disaccharides with various applications. Hyaluronic acid is a major component of the extracellular matrix (ECM). Hyaluronic acid is synthesized at the plasma membrane. Increased hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion and angiogenesis in digestive cancers. Hyaluronic acid participates in tissue remodeling and rapid cell proliferation in some physiological processes including embryonic morphogenesis and wound-healing. Hyaluronic acid activates the PI3K-Akt signaling. Hyaluronic acid acts as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid also enhances cell invasion and angiogenesis by promoting proteolytic MMP-9 binding to cell surface or stimulating MMP-9 binding to cell surface. Hyaluronic acid can be used as drug delivery for sodium butyrate to improve the anti-proliferative activity on breast cancer cell line. Hyaluronic acid can be studied in joint diseases, wound healing and cancer.
    Hyaluronic acid
  • HY-109506
    DPPC

    DPPC

    		63-89-8 99.91%
    DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice.
    DPPC
  • HY-113424A
    1,2-Dioleoyl-sn-glycero-3-phosphocholine

    1,2-Dioleoyl-sn-glycero-3-phosphocholine

    		4235-95-4 99.93%
    1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes.
    1,2-Dioleoyl-sn-glycero-3-phosphocholine
  • HY-138300
    ALC-0159 1849616-42-7 99.93%
    ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient.
    ALC-0159
  • HY-145405
    C12-200 1220890-25-4 99.91%
    C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B.
    C12-200