2. Disease Areas
  3. Inflammation or Immune System Disease
  4. Immunodeficiency Disease
  5. AIDS

AIDS

HIV/AIDS is the advanced stage of human immunodeficiency virus (HIV) infection, characterized by severe immunosuppression due to the depletion of CD4+ T cells, leading to opportunistic infections, malignancies, and other life-threatening complications. It is diagnosed when the CD4+ T cell count falls below 200 cells/μL or when specific opportunistic illnesses develop, reflecting profound immune system failure.

References:

AIDS (5):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-164201
    HIV-1 inhibitor-69 257891-65-9 99.39%
    HIV-1 inhibitor-69 is an HIV-1 reverse transcriptase inhibitor. HIV-1 inhibitor-69 protects cells against HIV-1 infection. HIV-1 inhibitor-69 can be used for the research of acquired immunodeficiency syndrome (AIDS).
    HIV-1 inhibitor-69
  • HY-180567
    PAC-Phe-Val 3088543-72-7
    PAC-Phe-Val is a potent HIV-1 protease inhibitor with an IC50 value of 33.10 nM. PAC-Phe-Val forms stable and strong interactions with critical active site residues, contributing to its high inhibitory potency. PAC-Phe-Val can be used for HIV/AIDS research.
    PAC-Phe-Val
  • HY-182506
    Azimexon 64118-86-1
    Azimexon (BM 12.531) is an orally active immunomodulator with radioprotective and antitumor activities. Azimexon prolongs survival in multiple mouse models, enhances immunity and hematopoiesis, and alleviates radiation injury and tumor metastasis. Azimexon causes reversible hemolytic anemia in rats and dogs, and exerts therapeutic activity against adjuvant-induced arthritis in rats. Azimexon can be used for the research of lung carcinoma, leukemia, multiple myeloma, lung tumor, arthritis, breast cancer and AIDS‑related complex.
    Azimexon
  • HY-180417
    U 88204 136816-76-7
    U 88204 is a potent HIV-1 reverse transcriptase (RT) inhibitor with an IC50 of 0.25 μM. U 88204 blocks HIV-1 replication in infected cells. U 88204 can be used for the research on HIV-infection and of acquired immunodeficiency syndrome (AIDs).
    U 88204
  • HY-105097
    Atevirdine mesylate 138540-32-6
    Atevirdine (U 87201E) mesylate is a nonnucleoside reverse transcriptase (NNRT) inhibitor. Atevirdine mesylate can inhibit human immunodeficiency virus type 1 (HIV-1) with an IC50 of 0.06-1.6 μM. Atevirdine mesylate shows highly synergistic effects against Zidovudine/Didanosine-resistant clinical isolates of HIV-1 companied with Zidovudine (HY-17413)/Didanosine (Hy-B0249). Atevirdine mesylate can be used for the research of AIDS.
    Atevirdine mesylate