U 88204
U 88204 is a potent HIV-1 reverse transcriptase (RT) inhibitor with an IC50 of 0.25 μM. U 88204 blocks HIV-1 replication in infected cells. U 88204 can be used for the research on HIV-infection and of acquired immunodeficiency syndrome (AIDs).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 136816-76-7
- 分子式: C21H25N5O
- 分子量:363.47
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT2 | CC50 |
10 μM
Compound: 4
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Cytotoxic concentration against MT-2 cells
Cytotoxic concentration against MT-2 cells
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[PMID: 7684450] |
U 88204 (compound 11) potently blocks HIV-1 replication in MT-2/IIIb, PBMC/D34, and H9/IIIb cells with ED50 values of 0.3 μM, 0.001 μM, and 0.04 μM, respectively, while showing low cytotoxicity (CC50 > 10 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 136816-76-7
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分子量 363.47
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分子式 C21H25N5O
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SMILES
O=C(C1=CC=2C=CC=CC2N1)N3CCN(C4=NC=CC=C4NC(C)C)CC3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
U 88204 関連分類
HY-180417 関連分類
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