Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO)
Based on 2066 publication(s) in Google Scholar
MCE Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO) is a blend of 6 pan-protease inhibitors for protection of protein integrity.The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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Storage :
-20°C, 2 years
Description & Advantages
MCE Endogenous proteins are produced and removed in a balanced state, so their cellular levels are generally stable under stable environmental conditions. However, protein production is greatly halted and degradation is enhanced when cells are studied in vitro. To prevent the degradation of proteins under such conditions, one can utilize a cocktail of inhibitors of those enzymes known to be present.
MCE Protease inhibitor cocktail is used in cell lysates or tissue extracts to increase protein stability. The cocktail functions to inhibit proteases that would degrade either phosphorylated or non-phosphorylated protein substrates.
MCE Protease inhibitor cocktail has been optimized and tested for mammalian cell and tissue extracts. It contains inhibitors with a broad specificity for serine, cysteine, and acid proteases, and aminopeptidases. This cocktail is supplied as a ready-to-use solution in DMSO.
Price Comparison
Protocol
Thaw at room temperature, add the inhibitor mixture to the lysate at 1:100 (v/v), and mix thoroughly.
Publications
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Journal Impact Factor
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Most Recent
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Signal Transduct Target TherIntegrative analysis of non-small cell lung cancer identifies Jumonji domain-containing 6/ETS homologous factor axis as a target to overcome radioresistance. [Abstract]2025 Dec 1;10(1):391. PMID: 41320721
Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO) purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Dec 1;10(1):391. [Abstract]
EHF knockdown reduced TGF-β/Smad3 expression and AKT/ERK phosphorylation of NSCLC cells, as assessed by western blot analyses.
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Signal Transduct Target Ther2025 Dec 3;10(1):394. PMID: 41330906
Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO) purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Dec 3;10(1):394. [Abstract]
Protein expressions and relative quantification of B2M, and MHC Class I in whole cell lysates derived from adipocyte fraction isolated from VAT across lean patients and obese patients (n = 3).
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Signal Transduct Target Ther2025 Nov 12;10(1):366. PMID: 41219186
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Cancer CellPaneth-like transition drives resistance to dual targeting of KRAS and EGFR in colorectal cancer. [Abstract]2025 Nov 13:S1535-6108(25)00451-9. PMID: 41237766
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Cancer Cell2024 Jun 10;42(6):968-984.e9. PMID: 38788719
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Cancer CelliASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding. [Abstract]2017 Nov 13;32(5):561-573.e6. PMID: 29033244
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CellSelective targeting of endothelial and perivascular angiocrine ROCK2 treats liver fibrosis. [Abstract]2026 Apr 30;189(9):2663-2683.e26. PMID: 41794026
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CellSympathetic-epithelial crosstalk governs tissue-resident memory T cell immunosurveillance in the skin. [Abstract]2026 Mar 5;189(5):1323-1340.e25. PMID: 41616781
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CellIntermittent fasting triggers interorgan communication to suppress hair follicle regeneration. [Abstract]2025 Jan 9;188(1):157-174.e22. PMID: 39674178
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CellA two-front nutrient supply environment fuels small intestinal physiology through differential regulation of nutrient absorption and host defense. [Abstract]2024 Oct 31;187(22):6251-6271.e20. PMID: 39427662
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Mol CancerTherapy-induced senescent tumor cell-derived extracellular vesicles promote colorectal cancer progression through SERPINE1-mediated NF-κB p65 nuclear translocation. [Abstract]2024 Apr 4;23(1):70. PMID: 38576002
Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO) purchased from MedChemExpress. Usage Cited in: Mol Cancer. 2024 Apr 4;23(1):70. [Abstract]
Western blot analysis of EVs markers and endoplasmic reticulum marker in whole cell lysates and EVs.
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Cell MetabAdipokine IL-11/IL-11Ra constrains sphingolipid metabolism to limit the thermogenic capacity of beige adipocytes. [Abstract]2026 May 14:S1550-4131(26)00151-8. PMID: 42140185
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Cell MetabQuercetin-derived microbial metabolite DOPAC potentiates CD8+ T cell anti-tumor immunity via NRF2-mediated mitophagy. [Abstract]2025 Oct 24:S1550-4131(25)00395-X. PMID: 41138722
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Cell MetabThe enedioic acid analog 326E alleviates metabolic dysfunction-associated steatohepatitis via dual targeting at ACLY and PPARα. [Abstract]2025 Oct 22:S1550-4131(25)00396-1. PMID: 41130202
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Cell Metab2025 Feb 4;37(2):413-428.e7. PMID: 39814017
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Cell MetabAstrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation. [Abstract]2024 Sep 3;36(9):2054-2068.e14. PMID: 38906140
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Cell Metab2023 Dec 5;35(12):2107-2118.e6. PMID: 37863051
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Cell ResThe AHCY-adenosine complex rewires mRNA methylation to enhance fatty acid biosynthesis and tumorigenesis. [Abstract]2026 Feb;36(2):152-172. PMID: 41549122
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ImmunityAstrocytic calcium-dependent enzyme PAD2 governs microglia activity to exacerbate amyloid pathology via citrullinated vimentin. [Abstract]2026 Jun 9;59(6):1579-1598.e9. PMID: 41962542
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ImmunityGasdermin-D-mediated epithelial-immune circuit synchronizes nutrient absorption and host defense in the small intestine. [Abstract]2025 Jul 22:S1074-7613(25)00309-7. PMID: 40712560
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ImmunityMetabolic regulator LKB1 controls adipose tissue ILC2 PD-1 expression and mitochondrial homeostasis to prevent insulin resistance. [Abstract]2024 Jun 11;57(6):1289-1305.e9. PMID: 38772366
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ImmunityDisruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety. [Abstract]2024 Mar 12;57(3):495-512.e11. PMID: 38395698
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ImmunityLipopolysaccharide-binding protein expression is increased by stress and inhibits monoamine synthesis to promote depressive symptoms. [Abstract]2023 Mar 14;56(3):620-634.e11. PMID: 36854305
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Nat MetabHK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma. [Abstract]2022 Oct;4(10):1306-1321. PMID: 36192599
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Cell Mol Immunol2024 Nov;21(11):1251-1265. PMID: 39164536
Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO) purchased from MedChemExpress. Usage Cited in: Cell Mol Immunol. 2024 Nov;21(11):1251-1265. [Abstract]
The cels were lysed with RIPA buffer in the presence of Protease Inhibitor Cocktail (HY-K0010) and Phosphatase inhibitor cocktail II (HY-K0022) and boiled for 10 min. Immunoblot analysis of OVA or TRP2 levels in the mitochondria of B16-F10 cells or constructed stable B16-F10 cell lines with mitochondria bearing model antigen (OVA or TRP2). Anti-VDAC1 was used as a loading control.
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Cell Mol Immunol2021 Apr;18(4):979-991. PMID: 33707686
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Cell Stem CellA human organoid drug screen identifies α2-adrenergic receptor signaling as a therapeutic target for cartilage regeneration. [Abstract]2024 Dec 5;31(12):1813-1830.e8. PMID: 39353427
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Nat Cell Biol2024 Nov;26(11):1943-1957. PMID: 39482354
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Nat Cell Biol2024 Sep;26(9):1545-1557. PMID: 38997456
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Nat Cell Biol2022 Apr;24(4):471-482. PMID: 35256774
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Cancer ResMTHFD2 Enhances cMYC O-GlcNAcylation to Promote Sunitinib Resistance in Renal Cell Carcinoma. [Abstract]2025 Mar 14;85(6):1113-1129. PMID: 39804969
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Cancer Res2023 Oct 2;83(19):3220-3236. PMID: 37463119
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Cancer ResRBM10 Loss Promotes EGFR-Driven Lung Cancer and Confers Sensitivity to Spliceosome Inhibition. [Abstract]2023 May 2;83(9):1490-1502. PMID: 36853175
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Cancer ResTRAF4 Maintains Deubiquitination of Caveolin-1 to Drive Glioblastoma Stemness and Temozolomide Resistance. [Abstract]2022 Oct 4;82(19):3573-3587. PMID: 35895752
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Cancer ResAfatinib Exerts Immunomodulatory Effects by Targeting the Pyrimidine Biosynthesis Enzyme CAD. [Abstract]2021 Jun 15;81(12):3270-3282. PMID: 33771897
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Sci BullHepatic IFRD1 suppresses metabolic dysfunction-associated fatty liver disease via GLUD1/α-KG axis. [Abstract]2026 May 15;71(9):2283-2299. PMID: 41997855
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AutophagyCircRNA GRAMD4 induces NBR1 expression to promote autophagy and immune escape in renal cell carcinoma. [Abstract]2025 Nov;21(11):2332-2352. PMID: 40373256
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AutophagyDefective autophagy contributes to endometrial epithelial-mesenchymal transition in intrauterine adhesions. [Abstract]2022 Oct;18(10):2427-2442. PMID: 35196191
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Nat Protoc2024 Jul;19(7):1984-2025. PMID: 38514838
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Protein Cell2025 Jan 4;16(1):28-48. PMID: 38721690
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Nat Commun2026 Feb 20;17(1):2963. PMID: 41720774
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Nat Commun2026 Jan 7;17(1):163. PMID: 41501012
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Nat Commun2025 Nov 26;16(1):10514. PMID: 41298370
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Nat Commun2025 Oct 15;16(1):9150. PMID: 41093827
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Nat Commun2025 Aug 10;16(1):7376. PMID: 40784880
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Nat Commun2025 Jul 1;16(1):6016. PMID: 40593722
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Nat CommunA cohort of mRNAs undergo high-stoichiometry NSUN6-mediated site-specific m5C modification. [Abstract]2025 Jul 4;16(1):6119. PMID: 40615396
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Nat CommunDe novo design of protein condensation inhibitors by targeting an allosteric site of cGAS. [Abstract]2025 Jun 3;16(1):5140. PMID: 40461475
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Nat CommunThe structural basis for the human procollagen lysine hydroxylation and dual-glycosylation. [Abstract]2025 Mar 11;16(1):2436. PMID: 40069201
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Nat CommunMaternal behavior promotes resilience to adolescent stress in mice through a microglia-neuron axis. [Abstract]2025 Mar 8;16(1):2333. PMID: 40057602
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Nat CommunMolecular basis for the regulation of human phosphorylase kinase by phosphorylation and Ca2. [Abstract]2025 Mar 28;16(1):3020. PMID: 40148320
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Nat Commun2024 Nov 16;15(1):9950. PMID: 39550386
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Nat CommunMitochondrial rewiring with small-molecule drug-free nanoassemblies unleashes anticancer immunity. [Abstract]2024 Sep 3;15(1):7664. PMID: 39227567
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Nat Commun2024 Aug 24;15(1):7287. PMID: 39179589
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Nat CommunDual-site molecular glues for enhancing protein-protein interactions of the CDK12-DDB1 complex. [Abstract]2024 Aug 1;15(1):6477. PMID: 39090085
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Nat CommunMycobacterium tuberculosis suppresses host antimicrobial peptides by dehydrogenating L-alanine. [Abstract]2024 May 17;15(1):4216. PMID: 38760394
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Nat Commun2023 Dec 21;14(1):8428. PMID: 38129407
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Nat CommunLactylation of METTL16 promotes cuproptosis via m6A-modification on FDX1 mRNA in gastric cancer. [Abstract]2023 Oct 20;14(1):6523. PMID: 37863889
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Nat CommunKK-LC-1 as a therapeutic target to eliminate ALDH+ stem cells in triple negative breast cancer. [Abstract]2023 May 5;14(1):2602. PMID: 37147285
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Nat Commun2023 May 12;14(1):2731. PMID: 37169793
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Nat Commun2022 Oct 12;13(1):6004. PMID: 36224181
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Nat Commun2022 Jul 8;13(1):3972. PMID: 35803934
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Nat CommunIL-22 initiates an IL-18-dependent epithelial response circuit to enforce intestinal host defence. [Abstract]2022 Feb 15;13(1):874. PMID: 35169117
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Nat CommunThe structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3. [Abstract]2021 Nov 25;12(1):6869. PMID: 34824256
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Int J Oral Sci2026 Feb 3;18(1):13. PMID: 41629272
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Int J Oral Sci2026 Jan 10;18(1):5. PMID: 41513627
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ACS NanoDisulfide-Appended siRNA Nanoeyedrops: Noninvasive Gene Therapy for Targeting Retinal Angiogenesis. [Abstract]2025 Oct 14;19(40):35333-35347. PMID: 41037347
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ACS NanoTargeting the Mitochondria with Pseudo-Stealthy Nanotaxanes to Impair Mitochondrial Biogenesis for Effective Cancer Treatment. [Abstract]2022 Jul 26;16(7):10242-10259. PMID: 35820199
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ACS NanoOxidation of Reduced Graphene Oxide via Cellular Redox Signaling Modulates Actin-Mediated Neurotransmission. [Abstract]2020 Mar 24;14(3):3059-3074. PMID: 32057235
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ACS NanoCiliotherapy: Remote Control of Primary Cilia Movement and Function by Magnetic Nanoparticles. [Abstract]2019 Mar 26;13(3):3555-3572. PMID: 30860808
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J Adv ResIFITM3 knockout alleviates neuronal parthanatos by restoring astrocytic glutamate uptake in intracerebral hemorrhage mice. [Abstract]2026 May 16:S2090-1232(26)00437-6. PMID: 42144055
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J Adv ResMDH1 K298 succinylation stabilizes redox homeostasis to protect against cardiac ferroptosis in ischemia-reperfusion injury. [Abstract]2026 Jul 6:S2090-1232(26)00529-1. PMID: 42409167
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J Adv ResElevated lactate production exacerbates PM2.5-induced pulmonary fibrosis by stabilizing TGF-β1. [Abstract]2025 Aug 5:S2090-1232(25)00587-9. PMID: 40759348
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Cell Discov2024 Oct 22;10(1):106. PMID: 39433541
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NeuronAstrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory. [Abstract]2021 Mar 17;109(6):957-970.e8. PMID: 33503410
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J Am Chem Soc2024 Apr 10;146(14):9779-9789. PMID: 38561350
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Sci ImmunolEpithelial Gasdermin D shapes the host-microbial interface by driving mucus layer formation. [Abstract]2022 Feb 4;7(68):eabk2092. PMID: 35119941
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Redox Biol2022 Aug;54:102383. PMID: 35797800
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Mol CellDeciphering the dual effects of transcription on DNA replication elongation by replication-associated Micro-C. [Abstract]2026 May 21;86(10):1870-1880.e5. PMID: 42019499
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Mol CellExtrachromosomal DNA biogenesis is dependent on DNA looping and religation by YY1-Lig3-PARylation complex. [Abstract]2025 Aug 21;85(16):3090-3107.e11. PMID: 40769147
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Mol CellSpatial control of m6A deposition on enhancer and promoter RNAs through co-acetylation of METTL3 and H3K27 on chromatin. [Abstract]2025 Apr 3;85(7):1349-1365.e10. PMID: 40101711
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Mol CellCryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals. [Abstract]2024 Jun 6;84(11):2152-2165.e5. PMID: 38781971
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Mol CellSMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation. [Abstract]2023 Dec 7;83(23):4352-4369.e8. PMID: 38016474
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Mol CellActivation and closed-state inactivation mechanisms of the human voltage-gated KV4 channel complexes. [Abstract]2022 Jul 7;82(13):2427-2442.e4. PMID: 35597238
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Mol CellWWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy. [Abstract]2022 May 19;82(10):1850-1864.e7. PMID: 35429439
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Mol CellSENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function. [Abstract]2021 Mar 4;81(5):940-952.e5. PMID: 33434504
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Gut Microbes2025 Dec;17(1):2508949. PMID: 40409349
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Nucleic Acids Res2024 Dec 11;52(22):14112-14132. PMID: 39673265
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Nucleic Acids Res2021 Nov 18;49(20):11900-11919. PMID: 34669960
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Nucleic Acids ResA role for LSH in facilitating DNA methylation by DNMT1 through enhancing UHRF1 chromatin association. [Abstract]2020 Dec 2;48(21):12116-12134. PMID: 33170271
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Microbiome2025 Jan 27;13(1):27. PMID: 39871363
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TheranosticsKindlin-2 enhances c-Myc translation through association with DDX3X to promote pancreatic ductal adenocarcinoma progression. [Abstract]2023 Jul 31;13(13):4333-4355. PMID: 37649609
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TheranosticsWnt4 is crucial for cardiac repair by regulating mesenchymal-endothelial transition via the phospho-JNK/JNK. [Abstract]2022 May 13;12(9):4110-4126. PMID: 35673578
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TheranosticsSIRT2 ablation inhibits glucose-stimulated insulin secretion through decreasing glycolytic flux. [Abstract]2021 Mar 4;11(10):4825-4838. PMID: 33754030
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TheranosticsLncRNA BCYRN1-induced autophagy enhances asparaginase resistance in extranodal NK/T-cell lymphoma. [Abstract]2021 Jan 1;11(2):925-940. PMID: 33391513
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Theranostics2020 Oct 30;10(26):12223-12240. PMID: 33204339
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TheranosticsO-GlcNAcylation of SIX1 enhances its stability and promotes Hepatocellular Carcinoma Proliferation. [Abstract]2020 Aug 2;10(21):9830-9842. PMID: 32863962
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TheranosticsLXR activation potentiates sorafenib sensitivity in HCC by activating microRNA-378a transcription. [Abstract]2020 Jul 11;10(19):8834-8850. PMID: 32754282
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Acta Pharm Sin BInsights into SARS-CoV-2 replication control via targeting the host hijacking function of NSP12. [Abstract]2026 Jul;16(7):4410-4425. PMID: 42453420
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Acta Pharm Sin B2025 Aug;15(8):4078-4095. PMID: 40893681
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Acta Pharm Sin BDNMT3A loss drives a HIF-1-dependent synthetic lethality to HDAC6 inhibition in non-small cell lung cancer. [Abstract]2024 Dec;14(12):5219-5234. PMID: 39807333
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Acta Pharm Sin BHepatic COX1 loss leads to impaired autophagic flux and exacerbates nonalcoholic steatohepatitis. [Abstract]2023 Jun;13(6):2628-2644. PMID: 37425048
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J Clin Invest2025 Oct 15;135(20):e195214. PMID: 41090353
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J Clin InvestTendon-derived cathepsin K-expressing progenitor cells activate Hedgehog signaling to drive heterotopic ossification. [Abstract]2020 Dec 1;130(12):6354-6365. PMID: 32853181
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J Exp Clin Cancer ResDysregulation of miR-6868-5p/FOXM1 circuit contributes to colorectal cancer angiogenesis. [Abstract]2018 Nov 28;37(1):292. PMID: 30486864
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Adv Sci (Weinh)2025 Dec 1:e08525. PMID: 41327885
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Adv Sci (Weinh)2025 Aug 11:e02535. PMID: 40787892
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Adv Sci (Weinh)Spatiotemporal Regulation of STING Activity by Linear Ubiquitination Governs Antiviral Immunity. [Abstract]2025 Jul;12(28):e2417660. PMID: 40536345
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Adv Sci (Weinh)Viridicatol from the Deep-Sea-Derived Fungus Alleviates Bone Loss by Targeting the Wnt/SHN3 Pathway. [Abstract]2025 Jun;12(21):e2416140. PMID: 40192033
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Adv Sci (Weinh)FGF2 Mediated USP42-PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration. [Abstract]2025 May;12(18):e2408724. PMID: 40091484
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Adv Sci (Weinh)Sirt6 Mono-ADP-Ribosylates YY1 to Promote Dystrophin Expression for Neuromuscular Transmission. [Abstract]2024 Nov;11(44):e2406390. PMID: 39387251
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Adv Sci (Weinh)The Thyroid Hormone Analog GC-1 Mitigates Acute Lung Injury by Inhibiting M1 Macrophage Polarization. [Abstract]2024 Nov;11(44):e2401931. PMID: 39373388
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Adv Sci (Weinh)Lactylated Apolipoprotein C-II Induces Immunotherapy Resistance by Promoting Extracellular Lipolysis. [Abstract]2024 Oct;11(38):e2406333. PMID: 38981044
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Adv Sci (Weinh)PXR Activation Relieves Deoxynivalenol-Induced Liver Oxidative Stress Via Malat1 LncRNA m6A Demethylation. [Abstract]2024 Jul;11(25):e2308742. PMID: 38654691
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Adv Sci (Weinh)Inhibition of CARM1-Mediated Methylation of ACSL4 Promotes Ferroptosis in Colorectal Cancer. [Abstract]2023 Dec;10(36):e2303484. PMID: 37946697
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Adv Sci (Weinh)Adamantaniline Derivatives Target ATP5B to Inhibit Translation of Hypoxia Inducible Factor-1α. [Abstract]2023 Sep;10(25):e2301071. PMID: 37401167
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Adv Sci (Weinh)A Recombinant Parathyroid Hormone-Related Peptide Locally Applied in Osteoporotic Bone Defect. [Abstract]2023 Aug;10(22):e2300516. PMID: 37229774
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Cell Rep MedTargeting pancreatic cancer glutamine dependency confers vulnerability to GPX4-dependent ferroptosis. [Abstract]2025 Feb 18;6(2):101928. PMID: 39879992
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Sci AdvCLOCK-catalyzed histone H3K37 glutarylation suppresses H3K36 trimethylation pathways in glioblastoma. [Abstract]2026 Mar 27;12(13):eaea1127. PMID: 41880493
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Sci AdvDLX2 acts as a pioneer factor and drives Msx1+ ectomesenchyme formation from embryonic stem cells. [Abstract]2026 Jan 16;12(3):eaea0685. PMID: 41533791
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Sci AdvERα activates NAMPT/IL-33 signaling to enhance beige thermogenesis and metabolic fitness. [Abstract]2026 Jan 9;12(2):eadz1385. PMID: 41499496
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Sci AdvVIRMA-mediated m6A modification regulates forebrain formation through modulating ribosome biogenesis. [Abstract]2025 Jun 27;11(26):eadq9643. PMID: 40577453
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Sci AdvWWC proteins-mediated compensatory mechanism restricts schwannomatosis driven by NF2 loss of function. [Abstract]2025 Jan 24;11(4):eadp4765. PMID: 39841844
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Sci AdvACSL6-activated IL-18R1-NF-κB promotes IL-18-mediated tumor immune evasion and tumor progression. [Abstract]2024 Sep 20;10(38):eadp0719. PMID: 39292786
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Sci AdvGenome-wide gain-of-function screening characterized lncRNA regulators for tumor immune response. [Abstract]2022 Dec 9;8(49):eadd0005. PMID: 36475797
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Sci AdvN-terminal signal peptides facilitate the engineering of PVC complex as a potent protein delivery system. [Abstract]2022 Apr 29;8(17):eabm2343. PMID: 35486720
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Sci AdvVGLL4 promotes osteoblast differentiation by antagonizing TEADs-inhibited Runx2 transcription. [Abstract]2020 Oct 23;6(43):eaba4147. PMID: 33097532
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Sci AdvRestriction of hepatitis B virus replication by c-Abl-induced proteasomal degradation of the viral polymerase. [Abstract]2019 Feb 6;5(2):eaau7130. PMID: 30775435
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Plant Commun2024 Jan 8;5(1):100776. PMID: 38050355
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Cell Death DifferVps34 sustains Treg cell survival and function via regulating intracellular redox homeostasis. [Abstract]2024 Nov;31(11):1519-1533. PMID: 39117783
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Cell Death Differ2024 Aug;31(8):1070-1084. PMID: 38816580
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Cell Death DifferiASPP suppression mediates terminal UPR and improves BRAF-inhibitor sensitivity of colon cancers. [Abstract]2023 Feb;30(2):327-340. PMID: 36380064
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Cell Death DifferTargeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma. [Abstract]2023 Feb;30(2):527-543. PMID: 36526897
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Cell Death Differ2022 Jun;29(6):1283-1295. PMID: 35022570
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Cell Death DifferA novel LncRNA HITT forms a regulatory loop with HIF-1α to modulate angiogenesis and tumor growth. [Abstract]2020 Apr;27(4):1431-1446. PMID: 31700144
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Plant CellComplex regulation of Citron OGD2-dependent resistance to citrus canker caused by Xanthomonas citri subsp. citri. [Abstract]2025 Oct 8;37(10):koaf225. PMID: 41066433
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Plant CellEthylene enhances MdMAPK3-mediated phosphorylation of MdNAC72 to promote apple fruit softening. [Abstract]2023 Aug 2;35(8):2887-2909. PMID: 37132483
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Neuro OncolLow level of tumor necrosis factor α in tumor microenvironment maintains self-renewal of glioma stem cells by Vasorin-mediated glycolysis. [Abstract]2024 Dec 5;26(12):2256-2271. PMID: 39093693
Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO) purchased from MedChemExpress. Usage Cited in: Neuro Oncol. 2024 Dec 5;26(12):2256-2271. [Abstract]
Co-immunoprecipitation of TNFR1 or VASN in T4121 and WF19 GSCs and immunoblotting for TNFR1 and VASN. IgG was used as the control antibody for IP.
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J Control Release2026 Feb 10:390:114571. PMID: 41443353
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J Control ReleaseTargeting polyamine metabolism induces oxidative/carbonyl stress to reinvigorate antitumor immunity in prostate cancer. [Abstract]2025 Sep 30;388(Pt 1):114283. PMID: 41038348
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Pharmacol Res2026 May:227:108169. PMID: 41871675
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Cell Death Dis2025 Aug 28;16(1):655. PMID: 40877231
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Cell Death Dis2025 May 6;16(1):362. PMID: 40328788
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Cell Death DisGPR56 facilitates hepatocellular carcinoma metastasis by promoting the TGF-β signaling pathway. [Abstract]2024 Oct 1;15(10):715. PMID: 39353900
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Cell Death Dis2024 May 9;15(5):325. PMID: 38724499
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Pharmacol Res2023 Sep:195:106881. PMID: 37541638
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Cell Death DisPathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats. [Abstract]2023 May 13;14(5):325. PMID: 37179386
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Cell Death Dis2022 Dec 5;13(12):1021. PMID: 36470870
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Cell Death Dis2022 Jul 23;13(7):643. PMID: 35871160
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Environ Sci TechnolChronic Exposure to Environmental Level Phenanthrene Induces Non-Obesity-Dependent Insulin Resistance in Male Mice. [Abstract]2020 Dec 1;54(23):15225-15234. PMID: 33171048
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Cell Death DismiR-486-3p mediates hepatocellular carcinoma sorafenib resistance by targeting FGFR4 and EGFR. [Abstract]2020 Apr 20;11(4):250. PMID: 32313144
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SmallTetrahedral DNA Nanostructure-Modified Nanocoating for Improved Bioaffinity and Osseointegration of Titanium. [Abstract]2025 May;21(18):e2412747. PMID: 40103513
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Cancer Lett2025 Apr 28:616:217532. PMID: 40021040
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Cancer LettPI3K PROTAC overcomes the lapatinib resistance in PIK3CA-mutant HER2 positive breast cancer. [Abstract]2024 Aug 28:598:217112. PMID: 38986734
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Cancer LettThe diverse pancreatic tumor cell-intrinsic response to IFNγ is determined by epigenetic heterogeneity. [Abstract]2023 May 28:562:216153. PMID: 37023939
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Cancer LettDAB2IP suppresses tumor malignancy by inhibiting GRP75-driven p53 ubiquitination in colon cancer. [Abstract]2022 Apr 28:532:215588. PMID: 35150809
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J Immunother CancerATF4 promotes immune evasion in oral squamous cell carcinoma by suppressing autophagic PD-L1 degradation. [Abstract]2026 May 28;14(5):e015038. PMID: 42208982
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Int J Biol SciA Novel PROTAC Confers a Dual Benefit Against Amyloid and Tau Pathology in Alzheimer's Disease via DAPK1 Degradation. [Abstract]2026 Apr 23;22(9):4724-4746. PMID: 42157943
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Int J Biol SciAPT1-derived depalmitoylation of CD36 alleviates diabetes-induced lipotoxicity in podocytes. [Abstract]2025 Jun 9;21(9):3852-3866. PMID: 40607256
-
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-
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-
Int J Biol Sci2022 Sep 11;18(15):5698-5712. PMID: 36263164
-
Int J Biol SciAtrial Natriuretic Peptide Attenuates Colitis via Inhibition of the cGAS-STING Pathway in Colonic Epithelial Cells. [Abstract]2022 Feb 7;18(4):1737-1754. PMID: 35280696
-
Int J Biol SciAldolase A Enhances Intrahepatic Cholangiocarcinoma Proliferation and Invasion through Promoting Glycolysis. [Abstract]2021 Apr 23;17(7):1782-1794. PMID: 33994862
-
Cell Commun SignalEffects of a novel ANLN E841K mutation associated with SRNS on podocytes and its mechanism. [Abstract]2023 Nov 13;21(1):324. PMID: 37957688
-
Cell Commun Signal2021 May 20;19(1):58. PMID: 34016129
-
Mol TherGenetically Engineered Nanovesicles Mobilize Synergistic Antitumor Immunity by ADAR1 Silence and PDL1 Blockade. [Abstract]2023 Aug 2;31(8):2489-2506. PMID: 37087570
-
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-
Mol TherlncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma. [Abstract]2022 Mar 2;30(3):1071-1088. PMID: 35017116
-
EBioMedicine2026 Apr:126:106213. PMID: 41861519
-
EBioMedicine2026 Feb:124:106119. PMID: 41506148
-
Angiogenesis2025 Apr 8;28(2):23. PMID: 40199774
-
J Hazard Mater2025 Aug 15:494:138515. PMID: 40359755
-
Cell Death Discov2025 Mar 6;11(1):89. PMID: 40050610
-
Acta Pharmacol SinAntiatherosclerotic effect of dehydrocorydaline on ApoE-/- mice: inhibition of macrophage inflammation. [Abstract]2022 Jun;43(6):1408-1418. PMID: 34552216
-
Acta Biomater2021 Apr 15:125:253-266. PMID: 33657452
-
Nat Struct Mol Biol2022 Mar;29(3):203-209. PMID: 35165458
-
J Transl MedSPICE1 promotes osteosarcoma growth by enhancing the deubiquitination of FASN mediated by USP10. [Abstract]2025 Feb 21;23(1):220. PMID: 39985078
-
J Transl Med2024 Jan 26;22(1):104. PMID: 38279172
-
J Transl Med2019 Aug 20;17(1):276. PMID: 31429774
-
J Nucl MedMonitoring T-Cell Activation in the Tumor Microenvironment by PET Imaging of the Chemokine CXCL9. [Abstract]2025 Sep 2;66(9):1372-1377. PMID: 40813232
-
Proc Natl Acad Sci U S A2025 Dec 2;122(48):e2508893122. PMID: 41284871
-
Chin Chem Lett2019 Dec;30(12):2201-2204. PMID: 32288403
-
DiabetesMetrnl alleviates lipid accumulation by modulating mitochondrial homeostasis in diabetic nephropathy. [Abstract]2023 May 1;72(5):611-626. PMID: 36812572
-
Dev CellRice extracellular vesicles send defense proteins into fungus Rhizoctonia solani to reduce disease. [Abstract]2025 Apr 21;60(8):1168-1181.e6. PMID: 39755117
-
Dev CellVery long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration. [Abstract]2024 Nov 18;59(22):3008-3024.e8. PMID: 39047737
-
Dev CellHepatocytic lipocalin-2 controls HDL metabolism and atherosclerosis via Nedd4-1-SR-BI axis in mice. [Abstract]2023 Nov 6;58(21):2326-2337.e5. PMID: 37863040
-
Dev CellGasdermin D maintains bone mass by rewiring the endo-lysosomal pathway of osteoclastic bone resorption. [Abstract]2022 Oct 24;57(20):2365-2380.e8. PMID: 36243012
-
OncogeneJMJD6 in tumor-associated macrophage regulates macrophage polarization and cancer progression via STAT3/IL-10 axis. [Abstract]2023 Sep;42(37):2737-2750. PMID: 37567973
-
OncogeneCelastrol recruits UBE3A to recognize and degrade the DNA binding domain of steroid receptors. [Abstract]2022 Oct;41(42):4754-4767. PMID: 36109631
-
OncogeneA lncRNA coordinates with Ezh2 to inhibit HIF-1α transcription and suppress cancer cell adaption to hypoxia. [Abstract]2020 Feb;39(9):1860-1874. PMID: 31784651
-
Cell Chem BiolSTT3A is essential for Wnt signaling and represents a target for cancers driven by RNF43 deficiency. [Abstract]2025 Oct 22:S2451-9456(25)00306-X. PMID: 41130209
-
Cell Chem Biol2025 Oct 16;32(10):1249-1259.e9. PMID: 41045931
-
Cell Chem Biol2024 Apr 18;31(4):776-791.e7. PMID: 37751743
-
Int J Biol MacromolDeubiquitinase USP45 stabilizes RTCB and DDX1, promoting tumorigenesis and chemoresistance. [Abstract]2025 Dec 28;339(Pt 2):149970. PMID: 41468936
-
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-
New Phytol2025 Oct;248(2):793-806. PMID: 40855607
-
Int J Biol MacromolBovine viral diarrhea virus E2 targets SLC3A2 to modulate lipid peroxidation for replication advantage. [Abstract]2025 Sep 13;329(Pt 1):147663. PMID: 40953614
-
New Phytol2025 Jul;247(2):651-668. PMID: 40016947
-
Int J NanomedicinePhytosomes Loaded with Mastoparan-M Represent a Novel Strategy for Breast Cancer Treatment. [Abstract]2025 Jan 9:20:109-124. PMID: 39816377
-
Int J Biol MacromolRole of Rab35 in modulating lipid metabolism and viral entry during pseudorabies virus infection. [Abstract]2024 Nov 9;282(Pt 6):137492. PMID: 39528177
-
Int J Biol Macromol2022 Oct 31:219:500-507. PMID: 35932807
-
Int J Biol Macromol2022 Feb 28:199:331-340. PMID: 35031312
-
New PhytolAn HD-ZIP-MYB complex regulates glandular secretory trichome initiation in Artemisia annua. [Abstract]2021 Sep;231(5):2050-2064. PMID: 34043829
-
Hum Reprod OpenBi-allelic variants in DNAH3 cause male infertility with asthenoteratozoospermia in humans and mice. [Abstract]2024 Jan 11;2024(1):hoae003. PMID: 38312775
-
aBIOTECHA pathogen-induced translational shift enhances plant disease resistance without obvious fitness costs. [Abstract]2026 Feb 3;7(2):100025. PMID: 41938348
-
Int J Mol Med2018 May;41(5):2784-2792. PMID: 29484381
-
Mol MedAcid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis. [Abstract]2022 Sep 6;28(1):106. PMID: 36068514
-
Plant PhysiolManipulation of the central autophagy component ZmATG8c affects thermotolerance in maize. [Abstract]2025 Sep 1;199(1):kiaf299. PMID: 40627785
-
Plant PhysiolThe effector SJP3 interferes with pistil development by sustaining SHORT VEGETATIVE PHASE 3 expression in jujube. [Abstract]2024 Nov 4;196(3):1923-1938. PMID: 39189604
-
Phytother ResXanthohumol Regulates Mitophagy in Osteosarcoma Cells via AMPK-ULK1-FUNDC1 Signaling Pathway. [Abstract]2025 May;39(5):2393-2406. PMID: 40190139
-
Free Radic Biol MedKaempferol alleviates inflammatory osteolysis by directly activating NRF2 in osteoclasts and modulating the immune microenvironment. [Abstract]2026 Feb 23:S0891-5849(26)00137-1. PMID: 41740690
-
Free Radic Biol MedTargeting β-catenin preserves gut vascular barrier integrity and attenuates gut-liver axis inflammation in ETEC infection. [Abstract]2025 Oct 8:S0891-5849(25)01267-5. PMID: 41072880
-
J Genet GenomicsSYMPK interacts with KIF20A and NUMA1 to coordinate spindle organization and safeguard oocyte meiotic maturation. [Abstract]2026 Jan 9:S1673-8527(26)00002-0. PMID: 41520922
-
EMBO Mol MedSpleen-targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma. [Abstract]2023 Oct 11;15(10):e16836. PMID: 37552209
-
EMBO Mol MedAllosteric inhibition of SHP2 uncovers aberrant TLR7 trafficking in aggravating psoriasis. [Abstract]2022 Mar 7;14(3):e14455. PMID: 34936223
-
Clin Transl Med2021 Aug;11(8):e510. PMID: 34459136
-
EMBO Mol MedReprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer. [Abstract]2021 Jan 11;13(1):e12798. PMID: 33283987
-
ACS Appl Mater InterfacesInhalable siRNA Nanoparticles for Enhanced Tumor-Targeting Treatment of KRAS-Mutant Non-Small-Cell Lung Cancer. [Abstract]2023 Jul 5;15(26):31273-31284. PMID: 37354089
-
Stem Cell Res TherEvery road leads to Rome: therapeutic effect and mechanism of the extracellular vesicles of human embryonic stem cell-derived immune and matrix regulatory cells administered to mouse models of pulmonary fibrosis through different routes. [Abstract]2022 Apr 12;13(1):163. PMID: 35413874
-
ACS Appl Mater InterfacesAscorbic Acid-PEI Carbon Dots with Osteogenic Effects as miR-2861 Carriers to Effectively Enhance Bone Regeneration. [Abstract]2020 Nov 11;12(45):50287-50302. PMID: 33121247
-
ACS Appl Mater Interfaces2020 Oct 21;12(42):47330-47341. PMID: 32997489
-
Cell RepIncreased yolk lipid mobilization promotes zebrafish post-segmentation growth via an Hnf4-lipoprotein axis. [Abstract]2026 Apr 21;45(5):117295. PMID: 42018437
-
Cell Rep4-octyl itaconate inhibits cytokine-mediated inflammation via alkylation of TYK2 and JAK1. [Abstract]2026 Mar 30;45(4):117179. PMID: 41915469
-
Cell RepMulti-site phosphorylation of a transcription factor orchestrates imidacloprid resistance in whitefly. [Abstract]2025 Dec 2;44(12):116638. PMID: 41335518
-
Cell RepPrenatal electroacupuncture modulates maternal-fetal immune activation via a brain-to-splenic signal. [Abstract]2025 Nov 25;44(11):116576. PMID: 41259207
-
Cell RepSLC6A8-mediated creatine uptake suppresses ERK2-FSP1 signaling and induces ferroptosis in colorectal cancer. [Abstract]2025 Sep 1;44(9):116139. PMID: 40892544
-
Aging CellDLK/JNK3 Upregulation Aggravates Hair Cell Senescence in Mice Cochleae via Excessive Autophagy. [Abstract]2025 Aug;24(8):e70099. PMID: 40356329
-
Cell RepThe Hippo pathway kinase MST1 mediates a feedback loop to maintain NLRP3 inflammasome homeostasis. [Abstract]2025 Jul 26;44(8):116076. PMID: 40716062
-
Cell RepVCPIP1 potentiates innate immune responses by non-catalytically reducing the ubiquitination of IRAK1/2. [Abstract]2025 Jun 27;44(7):115931. PMID: 40581931
-
Cell RepICP22-defined condensates mediate RNAPII deubiquitylation by UL36 and promote HSV-1 transcription. [Abstract]2024 Oct 8;43(10):114792. PMID: 39383039
-
Cell RepMitotic ER-mitochondria contact enhances mitochondrial Ca2+ influx to promote cell division. [Abstract]2024 Sep 28;43(10):114794. PMID: 39342616
-
Cell Rep4-octyl itaconate as a metabolite derivative inhibits inflammation via alkylation of STING. [Abstract]2023 Feb 28;42(3):112145. PMID: 36862550
-
Cell RepIdentification and characterization of long non-coding RNA Carip in modulating spatial learning and memory. [Abstract]2022 Feb 22;38(8):110398. PMID: 35196493
-
Curr BiolISP1-Anchored Polarization of GCβ/CDC50A Complex Initiates Malaria Ookinete Gliding Motility. [Abstract]2018 Sep 10;28(17):2763-2776.e6. PMID: 30146157
-
Cell ProlifLL-37 Inhibits TMPRSS2-Mediated S2' Site Cleavage and SARS-CoV-2 Infection but Not Omicron Variants. [Abstract]2025 Dec;58(12):e70060. PMID: 40375579
-
Cell ProlifSETD2 epidermal deficiency promotes cutaneous wound healing via activation of AKT/mTOR Signalling. [Abstract]2021 Jun;54(6):e13045. PMID: 33949020
-
Cell Prolif2020 Feb;53(2):e12744. PMID: 31840352
-
Ann NeurolCCNK gene deficiency influences neural progenitor cells via Wnt5a signaling in CCNK-related syndrome. [Abstract]2023 Dec;94(6):1136-1154. PMID: 37597256
-
Br J Pharmacol2023 Feb;180(3):287-307. PMID: 36166754
-
Br J Pharmacol2020 Jun;177(12):2848-2859. PMID: 32017040
-
J Med ChemIntegrated Strategic Design and In Situ Click Chemistry Approach to Rapid Discovery of Novel Potent Covalent TEAD Inhibitors. [Abstract]2026 May 14;69(9):10905-10923. PMID: 42085464
-
J Med ChemA Soluble Triantennary N-Acetylgalactosamine Camptothecin Prodrug for Hepatocellular Carcinoma-Targeted Therapy. [Abstract]2025 Aug 14;68(15):15563-15578. PMID: 40693725
-
Anal ChemCombining the NanaPPI Toolbox and AI-Driven Virtual Inhibitor Screening for the p53-MDM2 Interaction. [Abstract]2025 Jul 29;97(29):15687-15697. PMID: 40624834
-
J Med ChemPINK1-Dependent Mitophagy Inhibits Elevated Ubiquitin Phosphorylation Caused by Mitochondrial Damage. [Abstract]2023 Jun 8;66(11):7645-7656. PMID: 37248632
-
J Med ChemDiscovery of Potent and Highly Selective Interleukin-2-Inducible T-Cell Kinase Degraders with In Vivo Activity. [Abstract]2023 Apr 13;66(7):4979-4998. PMID: 36959108
-
Clin SciAIM2 inflammasome contributes to aldosterone-induced renal injury via endoplasmic reticulum stress. [Abstract]2022 Jan 14;136(1):103-120. PMID: 34935888
-
Anal ChemA Nongenetic Proximity-Induced FRET Strategy Based on DNA Tetrahedron for Visualizing the Receptor Dimerization. [Abstract]2020 Sep 1;92(17):11921-11926. PMID: 32689787
-
Clin SciγδT cells contribute to type 2 inflammatory profiles in eosinophilic chronic rhinosinusitis with nasal polyps. [Abstract]2019 Nov 29;133(22):2301-2315. PMID: 31722010
-
Genomics Proteomics Bioinformatics2025 May 10;23(1):qzaf008. PMID: 39957240
-
Environ Pollut2021 Sep 15:285:117083. PMID: 33965856
-
Environ PollutLong-term exposure to environmental levels of phenanthrene disrupts spermatogenesis in male mice. [Abstract]2021 Sep 15:285:117488. PMID: 34090074
-
Sci SignalUSP5 deubiquitylates and stabilizes FcεRIγ to enhance IgE-induced mast cell activation and allergic inflammation. [Abstract]2025 Jul 29;18(897):eadr3411. PMID: 40729432
-
J Invest DermatolTRPV3-Activated PARP1/AIFM1/MIF Axis through Oxidative Stress Contributes to Atopic Dermatitis. [Abstract]2024 Dec;144(12):2695-2705.e8. PMID: 38823435
-
Emerg Microbes InfectInhibition of RAN attenuates influenza a virus replication and nucleoprotein nuclear export. [Abstract]2024 Dec;13(1):2387910. PMID: 39087696
-
Cancer Cell IntPrognosis of Midkine and AT1R expression in resectable head and neck squamous cell carcinoma. [Abstract]2023 Sep 24;23(1):212. PMID: 37743493
-
Sci Signal2020 Oct 27;13(655):eaay9217. PMID: 33109748
-
Pharmaceutics2020 Oct 9;12(10):950. PMID: 33050126
-
VirulenceHemocyanin controls Vibrio levels in hemolymph by modulating intracellular ROS via p38 MAPK. [Abstract]2025 Dec;16(1):2546066. PMID: 40852966
-
Antioxid Redox SignalThe antioxidant ergothioneine alleviates cisplatin-induced hearing loss through the Nrf2 pathway. [Abstract]2025 Jan;42(1-3):97-114. PMID: 38770822
-
Neurosci BullKIF17 Modulates Epileptic Seizures and Membrane Expression of the NMDA Receptor Subunit NR2B. [Abstract]2022 Aug;38(8):841-856. PMID: 35678994
-
Neurosci Bull2022 Jun;38(6):637-651. PMID: 35267139
-
Hum ReprodTaurine and its transporter TAUT positively affect male reproduction and early embryo development. [Abstract]2022 May 30;37(6):1229-1243. PMID: 35526154
-
JCI InsightMutations in OSBPL2 cause hearing loss associated with primary cilia defects via sonic hedgehog signaling. [Abstract]2022 Feb 22;7(4):e149626. PMID: 35041619
-
JCI Insight2021 Oct 8;6(19):e147716. PMID: 34622800
-
JCI InsightEndothelial cell prostaglandin E2 receptor EP4 is essential for blood pressure homeostasis. [Abstract]2020 Jul 9;5(13):e138505. PMID: 32641583
-
J Agric Food ChemVitamin D 3 Metabolite-Enhanced Hepatic VDR-FXR Binding Attenuates Bile Acid Dysregulation-Induced Diarrhea in Weaned Piglets. [Abstract]2026 Apr 22;74(15):12069-12086. PMID: 41952052
-
J Agric Food ChemButachlor-Induced BAZ2B Activation Promotes Cardiomyocyte Senescence through cGAS-STING pathway. [Abstract]2026 Mar 25;74(11):9761-9773. PMID: 41823793
-
J Agric Food Chem2025 Feb 26;73(8):4923-4935. PMID: 39934003
-
J Agric Food ChemNon-nutritive Sweetener Aspartame Disrupts Circadian Behavior and Causes Memory Impairment in Mice. [Abstract]2024 Oct 23;72(42):23478-23492. PMID: 39382230
-
J Agric Food ChemAQP1 Deficiency Drives Phthalate-Induced Epithelial Barrier Disruption through Intestinal Inflammation. [Abstract]2024 Jul 10;72(27):15334-15344. PMID: 38916549
-
J Agric Food ChemInhibition of the p62-Nrf2-GPX4 Pathway Confers Sensitivity to Butachlor-Induced Splenic Macrophage Ferroptosis. [Abstract]2024 Jul 31;72(30):16998-17007. PMID: 39016055
-
J Agric Food ChemSulforaphane Ameliorate Cadmium-Induced Blood-Thymus Barrier Disruption by Targeting the PI3K/AKT/FOXO1 Axis. [Abstract]2024 Jun 12;72(23):13382-13392. PMID: 38814005
-
J Agric Food ChemStructures, Biosynthesis, and Bioactivity of Oligomycins from the Marine-Derived Streptomyces sp. FXY-T5. [Abstract]2024 Jan 17;72(2):1082-1095. PMID: 38169320
-
Eur J Med Chem2023 Nov 15:260:115732. PMID: 37651876
-
Eur J Med Chem2019 Jun 15:172:174-185. PMID: 30978562
-
Ecotoxicol Environ Saf2023 Apr 15:255:114804. PMID: 36948007
-
Ecotoxicol Environ SaflncRNA AABR07005593.1 potentiates PM2.5-induced interleukin-6 expression by targeting MCCC1. [Abstract]2021 Dec 15:226:112834. PMID: 34619471
-
J Dent Res2017 Sep;96(10):1153-1161. PMID: 28489485
-
Biochem Pharmacol5-Methoxyseselin inhibits neuronal ferroptosis and β-amyloid production in female APP/PS1 transgenic mice. [Abstract]2026 Jun 25;251(Pt 2):118188. PMID: 42349617
-
Biochem PharmacolIsoalantolactone targets NLRP3 to disrupt NLRP3-NEK7 interaction and suppress inflammasome activation. [Abstract]2026 Jun 13;251(Pt 2):118165. PMID: 42288193
-
Cell BiosciLARP1 acts as a key mediator in preventing angiotensin II-induced cardiac dysfunction and fibrosis. [Abstract]2025 Oct 22;15(1):143. PMID: 41126333
-
Cell Biosci2025 Oct 23;15(1):146. PMID: 41131638
-
Biochem Pharmacol2025 Jul 16:241:117178. PMID: 40680865
-
Biochem Pharmacol2024 Oct:228:115936. PMID: 38012969
-
Cell BiosciSOX2 interacts with hnRNPK to modulate alternative splicing in mouse embryonic stem cells. [Abstract]2024 Aug 19;14(1):102. PMID: 39160617
-
Cell Biosci2023 May 11;13(1):84. PMID: 37170317
-
Mol Ther Nucleic Acids2021 Nov 3:26:1215-1227. PMID: 34853721
-
Life SciGLIPR2 regulates EndoMT and cardiac fibrosis after AMI via PDGFRL/AKT/mTOR signaling pathway. [Abstract]2025 Oct 1:378:123816. PMID: 40543810
-
Food FunctCyclo-(Phe-Tyr) reduces cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction through regulation of autophagy. [Abstract]2022 Nov 28;13(23):12278-12290. PMID: 36345882
-
Inflamm Res2024 Nov;73(11):1961-1979. PMID: 39292271
-
J Cell BiolAccumulated precursors of specific GPI-anchored proteins upregulate GPI biosynthesis with ARV1. [Abstract]2023 May 1;222(5):e202208159. PMID: 36828365
-
RSC AdvThe influence of gut microbiota on the rheological characterization of soy hull polysaccharide and mucin interactions. [Abstract]2020 Jan 15;10(5):2830-2840. PMID: 35496104
-
EMBO RepPCAF-mediated acetylation regulates RAD51 dynamic localization on chromatin during HR repair. [Abstract]2025 Aug;26(16):4100-4123. PMID: 40664718
-
EMBO RepTargeting the transcription factor YY1 is synthetic lethal with loss of the histone demethylase KDM5C. [Abstract]2024 Dec;25(12):5408-5428. PMID: 39433896
-
CellsSprouty2 Regulates Endocytosis and Degradation of Fibroblast Growth Factor Receptor 1 in Glioblastoma Cells. [Abstract]2024 Nov 28;13(23):1967. PMID: 39682716
-
Neurobiol Dis2023 Jun 1:181:106103. PMID: 36997128
-
CellsProteome and Glycoproteome Analyses Reveal the Protein N-Linked Glycosylation Specificity of STT3A and STT3B. [Abstract]2022 Sep 6;11(18):2775. PMID: 36139350
-
Commun Biol2026 Apr 17;9(1):834. PMID: 41998273
-
Commun Biol2025 Mar 7;8(1):385. PMID: 40055493
-
Commun Biol2023 Mar 11;6(1):259. PMID: 36906698
-
Commun BiolHomodimerized cytoplasmic domain of PD-L1 regulates its complex glycosylation in living cells. [Abstract]2022 Aug 30;5(1):887. PMID: 36042378
-
Eur J Pharmacol2026 Jun 24:1030:179089. PMID: 42342060
-
Eur J Pharmacol2026 Apr 15:1021:178825. PMID: 41905444
-
Eur J PharmacolIsolinderalactone targets TNF-α/STAT3 inflammatory pathways to attenuate psoriasis-like dermatitis. [Abstract]2026 Mar 28:1019:178733. PMID: 41795538
-
Eur J PharmacolDNMT3A-regulated medial prefrontal cortex circuits modulate paclitaxel-induced neuropathic pain. [Abstract]2026 Mar 28:1019:178674. PMID: 41740780
-
Eur J PharmacolIntegration of transcriptomics and metabolomics to reveal crizotinib-induced liver injury in mice. [Abstract]2025 Nov 5:1006:178096. PMID: 40914267
-
Respir Res2025 Feb 19;26(1):59. PMID: 39972348
-
J Endocrinol2020 Mar;244(3):445-458. PMID: 31846437
-
Int J Mol Sci2026 May 20;27(10):4593. PMID: 42196570
-
Int J Mol SciDual Pathways of UBE4B Inhibit Apoptosis in p53-Positive Tumor Cells via CCAR2 Degradation. [Abstract]2026 Apr 21;27(8):3682. PMID: 42074320
-
Int J Mol Sci2026 Apr 10;27(8):3425. PMID: 42074068
-
Int J Mol SciImpact of PKC-MAPK Signaling on Cardiac Sympathetic Overactivation in Type-2 Diabetes Mellitus. [Abstract]2026 Jan 10;27(2):723. PMID: 41596372
-
Int J Mol Sci2026 Jan 22;27(2):1119. PMID: 41596759
-
Int ImmunopharmacolHMOX1 expression influence the role of macrophage in EGFR-TKI resistance of lung adenocarcinoma. [Abstract]2026 Jan 1;168(Pt 1):115795. PMID: 41205382
-
Int J Mol Sci2025 Oct 22;26(21):10257. PMID: 41226300
-
Int J Mol Sci2025 Aug 5;26(15):7560. PMID: 40806687
-
Int J Mol SciLinear Ubiquitination of Hemocyanin Mediated by LUBEL Regulates Innate Immunity in Penaeus vannamei. [Abstract]2025 May 26;26(11):5110. PMID: 40507921
-
Int J Mol Sci2024 Dec 21;25(24):13673. PMID: 39769435
-
Int J Mol SciThe Discovery of a Specific CKIP-1 Ligand for the Potential Treatment of Disuse Osteoporosis. [Abstract]2024 Aug 15;25(16):8870. PMID: 39201556
-
Int ImmunopharmacolProcessing of angiocrine alarmin IL-1α in endothelial cells promotes lung and liver fibrosis. [Abstract]2024 Jun 15:134:112176. PMID: 38723369
-
Int Immunopharmacol2024 Jan 25:127:111411. PMID: 38113689
-
Int J Mol Sci2023 Nov 15;24(22):16363. PMID: 38003549
-
Int J Mol SciFARSB Facilitates Hepatocellular Carcinoma Progression by Activating the mTORC1 Signaling Pathway. [Abstract]2023 Nov 24;24(23):16709. PMID: 38069034
-
Int Immunopharmacol2023 Sep 3;124(Pt A):110889. PMID: 37669599
-
Int J Mol SciPARM1 Drives Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension via AKT/FOXO3A Axis. [Abstract]2023 Mar 28;24(7):6385. PMID: 37047359
-
Int Immunopharmacol2023 Mar:116:109810. PMID: 36774858
-
Int J Mol SciThe Effect of the Histone Chaperones HSPA8 and DEK on Tumor Immunity in Hepatocellular Carcinoma. [Abstract]2023 Jan 31;24(3):2653. PMID: 36768989
-
Int J Mol SciTranscriptional Regulation of Siglec-15 by ETS-1 and ETS-2 in Hepatocellular Carcinoma Cells. [Abstract]2023 Jan 2;24(1):792. PMID: 36614238
-
Int Immunopharmacol2022 Dec;113(Pt A):109308. PMID: 36274487
-
Int J Mol SciNovel Loss-of-Function Variant in HNF1a Induces β-Cell Dysfunction through Endoplasmic Reticulum Stress. [Abstract]2022 Oct 27;23(21):13022. PMID: 36361808
-
Int J Mol Sci2022 May 16;23(10):5543. PMID: 35628353
-
Int J Mol Sci2021 Aug 26;22(17):9245. PMID: 34502151
-
Zool ResMetformin improves boar sperm quality via 5'-AMP-activated protein kinase-mediated energy metabolism in vitro. [Abstract]2020 Sep 18;41(5):527-538. PMID: 32738111
-
Inflamm Bowel Dis2025 Sep 29:izaf099. PMID: 41017740
-
Mol NeurobiolInhibiting SNX14 Alleviates Epileptic Seizures by Regulating GluA2 Degradation via the Lysosomal Pathway. [Abstract]2025 Aug;62(8):10902-10914. PMID: 40237949
-
Mol NeurobiolAQP4 Endocytosis-Lysosome Degradation Mediated by MMP-9/β-DG Involved in Diabetes Cognitive Impairment. [Abstract]2024 Oct;61(10):8438-8453. PMID: 38512439
-
mBioTRIM25 promotes antiviral innate immune response by stabilizing IRF7 and its nuclear translocation. [Abstract]2026 May 13;17(5):e0047026. PMID: 41919938
-
Front PharmacolFGFC1 overcomes Ara-C resistance in acute myeloid leukemia by inducing apoptosis and pyroptosis. [Abstract]2025 Aug 14:16:1584376. PMID: 40894196
-
Am J Physiol Cell PhysiolIdentification of FOXP3+ epithelial cells contributing to pancreatic proliferation and angiogenesis. [Abstract]2024 Jan 1;326(1):C294-C303. PMID: 38047300
-
InflammationAnti-inflammatory Effect of a Limonin Derivative In Vivo and Its Mechanisms in RAW264.7 Cells. [Abstract]2023 Feb;46(1):190-201. PMID: 35986873
-
Inflammation2023 Feb;46(1):404-417. PMID: 36181623
-
InflammationmiR-128-3p Inhibits NRP1 Expression and Promotes Inflammatory Response to Acute Kidney Injury in Sepsis. [Abstract]2020 Oct;43(5):1772-1779. PMID: 32500307
-
MoleculesTwo-Dimensional NMR Spectroscopy of the G Protein-Coupled Receptor A2AAR in Lipid Nanodiscs. [Abstract]2023 Jul 14;28(14):5419. PMID: 37513291
-
World J DiabetesTongxinluo promotes endothelium-dependent arteriogenesis to attenuate diabetic peripheral arterial disease. [Abstract]2023 Mar 15;14(3):234-254. PMID: 37035233
-
Mol Med Rep2023 Dec;28(6):234. PMID: 37921069
-
Mol Med RepSpinosin and 6'''‑Feruloylspinosin protect the heart against acute myocardial ischemia and reperfusion in rats. [Abstract]2019 Nov;20(5):4253-4261. PMID: 31545438
-
PLoS PathogMicrosporidian Encephalitozoon hellem inhibits host mitophagy by inducing ERAD to degrade BNIP3L. [Abstract]2026 Mar 23;22(3):e1014078. PMID: 41871091
-
PLoS PathogWhite spot syndrome virus IE1 protein hijacks the host pentose phosphate pathway to fuel viral replication. [Abstract]2026 Jan 27;22(1):e1013913. PMID: 41592137
-
PLoS PathogEnP1 exploits H2Aub-dependent epigenetic reprogramming to promote microsporidia proliferation in host cells. [Abstract]2026 Jan 7;22(1):e1013853. PMID: 41499632
-
Sci RepNovel m5C-dependent post-transcriptional regulation of KIF11 drives lymphatic metastasis in gastric cancer. [Abstract]2025 Dec 29;15(1):44782. PMID: 41462498
-
Ann MedMulti-omics analysis and validation of autophagy-related diagnostic biomarker in osteoarthritis. [Abstract]2025 Dec;57(1):2548045. PMID: 40828304
-
Sci RepMycl, activated by Sgk1-phosphorylated Stat3, mediates osteoclastogenesis via Ctsk transcriptional regulation. [Abstract]2025 Nov 20;15(1):40945. PMID: 41266497
-
Sci RepCholesterol-modulating effects of Korean red ginseng (KRG) targeting PCSK9 in hyperlipidemia. [Abstract]2025 Aug 20;15(1):30637. PMID: 40836000
-
Sci RepIL-15-Activated CD38+HLA-DR+CD8+ T cells induce liver injury in cirrhosis via JAK/STAT5 and PI3K/mTOR pathways. [Abstract]2025 May 21;15(1):17612. PMID: 40399368
-
Ann MedAnalysis and identification of ferroptosis-related diagnostic markers in rheumatoid arthritis. [Abstract]2024 Dec;56(1):2397572. PMID: 39221753
-
Sci RepUBR1 promotes anaplastic thyroid carcinoma progression via stabilizing YAP through monoubiquitylation. [Abstract]2024 Aug 22;14(1):19496. PMID: 39174635
-
PLoS Pathog2024 Jul 22;20(7):e1012379. PMID: 39037956
-
Sci RepA tumor targeted nano micelle carrying astragaloside IV for combination treatment of bladder cancer. [Abstract]2024 Jul 31;14(1):17704. PMID: 39085255
-
J Lipid Res2024 Jun;65(6):100559. PMID: 38729351
-
Int J CancerTGFβ-induced EN1 promotes tumor budding of adenoid cystic carcinoma in patient-derived organoid model. [Abstract]2024 May 15;154(10):1814-1827. PMID: 38282121
-
PLoS PathogSRPK2 Mediates HBV Core Protein Phosphorylation and Capsid Assembly via Docking Interaction. [Abstract]2024 Feb 7;20(2):e1011978. PMID: 38324561
-
Cancer Sci2023 Oct;114(10):3900-3913. PMID: 37519194
-
Cancer SciChemokine C-C motif ligand 21 synergized with programmed death-ligand 1 blockade restrains tumor growth. [Abstract]2021 Nov;112(11):4457-4469. PMID: 34402138
-
Cancer SciPSMB8 inhibition decreases tumor angiogenesis in glioblastoma through vascular endothelial growth factor A reduction. [Abstract]2020 Nov;111(11):4142-4153. PMID: 32816328
-
PLoS PathogThe NS1 protein of the parvovirus MVM Aids in the localization of the viral genome to cellular sites of DNA damage. [Abstract]2020 Oct 16;16(10):e1009002. PMID: 33064772
-
Sci RepGLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes. [Abstract]2020 Aug 3;10(1):13063. PMID: 32747664
-
Cancer Sci2020 May;111(5):1567-1581. PMID: 32133742
-
Sci RepCharacterization of transgenic rice expressing fusion protein Cry1Ab/Vip3A for insect resistance. [Abstract]2018 Oct 25;8(1):15788. PMID: 30361672
-
MicroorganismsDesign, Synthesis, and Antiviral Evaluation of Novel 3,4-Dihydropyrimidin-2(1 H)-one Derivatives. [Abstract]2026 May 28;14(6):1220. PMID: 42354845
-
J Mol Biol2025 May 1;437(9):169034. PMID: 40010432
-
Mol Cell BiochemUFM1 inhibits hypoxia-induced angiogenesis via promoting proteasome degradation of HIF-1α. [Abstract]2024 Jul;479(7):1833-1852. PMID: 38722467
-
Virol SinPseudorabies virus manipulates mitochondrial tryptophanyl-tRNA synthetase 2 for viral replication. [Abstract]2024 Jun;39(3):403-413. PMID: 38636706
-
Virol SinMutual antagonism of mouse-adaptation mutations in HA and PA proteins on H9N2 virus replication. [Abstract]2024 Feb;39(1):56-70. PMID: 37967718
-
J Cell Mol Med2022 Jan;26(2):491-506. PMID: 34866322
-
J Drug TargetConstructing a better binding peptide for drug delivery targeting the interleukin-4 receptor. [Abstract]2020 Nov;28(9):970-981. PMID: 32363946
-
Virol SinThe Establishment of Infectious Clone and Single Round Infectious Particles for Coxsackievirus A10. [Abstract]2020 Aug;35(4):426-435. PMID: 32144688
-
Oncol RepThapsigargin promotes colorectal cancer cell migration through upregulation of lncRNA MALAT1. [Abstract]2020 Apr;43(4):1245-1255. PMID: 32323831
-
J Cell Mol Med2019 Jan;23(1):155-166. PMID: 30370662
-
Virol SinThe Scorpion Venom Peptide Smp76 Inhibits Viral Infection by Regulating Type-I Interferon Response. [Abstract]2018 Dec;33(6):545-556. PMID: 30569290
-
J Neurochem2025 Mar;169(3):e70026. PMID: 40026213
-
Biomedicines2026 May 9;14(5):1075. PMID: 42193400
-
Acta Biochim Biophys Sin (Shanghai)Metabolic reprogramming promotes AR-V7 splicing via SRSF2 lactylation in castration-resistant prostate cancer. [Abstract]2026 Apr 30;Vol.(1):fpage-lpage. PMID: 42178282
-
ACS Chem NeurosciObacunone Alleviates Thalamic Pain via Promoting LCN2-Mediated Phagocytosis of Astrocytes in Mice. [Abstract]2025 Jul 2;16(13):2546-2558. PMID: 40512028
-
ACS Synth Biol2025 Jan 17;14(1):148-160. PMID: 39763210
-
Neurochem ResScavenger Receptor Class B Type I Modulates Epileptic Seizures and Receptor α2δ-1 Expression. [Abstract]2024 Oct;49(10):2842-2853. PMID: 39017956
-
iScienceGRP94 promotes anoikis resistance and peritoneal metastasis through YAP/TEAD1 pathway in gastric cancer. [Abstract]2024 Aug 7;27(9):110638. PMID: 39252968
-
Brain Res Bull2023 Dec:205:110806. PMID: 37918696
-
Clin Exp MedOverexpression of HSPB6 inhibits osteosarcoma progress through the ERK signaling pathway. [Abstract]2023 Dec;23(8):5389-5398. PMID: 37861934
-
Neurochem Res2023 Sep;48(9):2826-2834. PMID: 37148458
-
iScienceZebrafish functional xenograft vasculature platform identifies PF-502 as a durable vasculature normalization drug. [Abstract]2023 Aug 24;26(9):107734. PMID: 37680473
-
iScienceTOPK mediates immune evasion of renal cell carcinoma via upregulating the expression of PD-L1. [Abstract]2023 Jun 20;26(7):107185. PMID: 37404377
-
iScienceLAPTM4B-YAP loop feedback amplification enhances the stemness of hepatocellular carcinoma. [Abstract]2023 Apr 27;26(6):106754. PMID: 37213231
-
iSciencePluripotency retention and exogenous mRNA introduction in planarian stem cells in culture. [Abstract]2023 Jan 20;26(2):106001. PMID: 36866042
-
iScienceSwine acute diarrhea syndrome coronavirus induces autophagy to promote its replication via the Akt/mTOR pathway. [Abstract]2022 Nov 18;25(11):105394. PMID: 36281226
-
iScienceHypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE. [Abstract]2022 Aug 4;25(9):104872. PMID: 36034219
-
iScienceSplicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium. [Abstract]2021 Sep 10;24(10):103097. PMID: 34622152
-
Neurochem ResEffects of NMDAR Antagonist on the Regulation of P-MARCKS Protein to Aβ1-42 Oligomers Induced Neurotoxicity. [Abstract]2018 Oct;43(10):2008-2015. PMID: 30155805
-
Front Mol Neurosci2022 Mar 2;15:762544. PMID: 35310885
-
J NeurosciCaMKIIβ-mediated Phosphorylation Enhances Protein Stability of Spastin to Promote Neurite Outgrowth. [Abstract]2025 Aug 6;45(32):e1995242025. PMID: 40645772
-
FASEB JCDK11 Mediates Autophagy to Promote Breast Cancer Cell Proliferation and Migration by Regulating BCL-2. [Abstract]2025 Aug 31;39(16):e70997. PMID: 40853089
-
FASEB JLycium barbarum Polysaccharide Ameliorates Hindlimb Unloading-Induced Bone Loss by Targeting Noggin. [Abstract]2025 Jul 15;39(13):e70795. PMID: 40635498
-
FASEB JGαq/11 Signaling Modulates Fibroblast Growth Factor 23 Production and Contributes to Acute Kidney Injury. [Abstract]2025 Apr 30;39(8):e70544. PMID: 40275688
-
Antiviral Res2024 Nov:231:106004. PMID: 39265655
-
FASEB JBrown adipose tissue-derived exosomes improve polycystic ovary syndrome in mice via STAT3/GPX4 signaling pathway. [Abstract]2024 Sep 30;38(18):e70062. PMID: 39305125
-
FASEB JTRAF2 decrease promotes the TGF-β-mTORC1 signal in MAFLD-HCC through enhancing AXIN1-mediated Smad7 degradation. [Abstract]2024 Feb 29;38(4):e23491. PMID: 38363556
-
Biochim Biophys Acta Mol Cell Res2023 Nov 22;1871(2):119642. PMID: 37996058
-
J NeurosciMicroglial Tmem59 Deficiency Impairs Phagocytosis of Synapse and Leads to Autism-Like Behaviors in Mice. [Abstract]2022 Jun 22;42(25):4958-4979. PMID: 35606143
-
J Pharmacol Exp Ther2020 Apr;373(1):149-159. PMID: 32015160
-
Chem Commun (Camb)Photothermal therapy-induced immunogenic cell death based on natural melanin nanoparticles against breast cancer. [Abstract]2020 Jan 30;56(9):1389-1392. PMID: 31912821
-
Nanomedicine (Lond)Theranostic micelles combined with multiple strategies to effectively overcome multidrug resistance. [Abstract]2018 Jul;13(13):1517-1533. PMID: 30028224
-
Mol Hum ReprodDown-regulation of IGFBP2 mediates endometrial epithelial cells senescence in thin endometrium. [Abstract]2025 Jul 3;31(3):gaaf032. PMID: 40700608
-
Mol Hum ReprodEutopic macrophages facilitate endometriosis progression via ferroptosis-mediated release of S100A9. [Abstract]2025 Apr 3;31(2):gaaf027. PMID: 40493892
-
Pest Manag Sci2025 Jan;81(1):28-35. PMID: 39300681
-
FEBS JRadiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy. [Abstract]2023 Jul;290(14):3629-3645. PMID: 36871142
-
J NutrAmuc Prevents Liver Inflammation and Oxidative Stress in Mice Challenged with Salmonella Typhimurium. [Abstract]2023 Feb;153(2):532-542. PMID: 36894245
-
Mol Hum ReprodHMGA2-induced epithelial-mesenchymal transition is reversed by let-7d in intrauterine adhesions. [Abstract]2021 Feb 5;27(2):gaaa074. PMID: 33237328
-
Microbiol Spectr2026 Jun 2;14(6):e0160825. PMID: 41995456
-
J VirolNipah virus matrix protein promotes NF-κB activation by targeting multiple signaling modulators. [Abstract]2026 Jun 23;100(6):e0018526. PMID: 42165681
-
J Biol ChemHexosamine biosynthesis drives hemocyanin O-GlcNAcylation to potentiate antibacterial immunity in shrimp. [Abstract]2026 May 28;302(7):113213. PMID: 42214671
-
J Biol ChemCytosolic nucleic acid sensing triggers type I interferon activation via the Hippo kinase LATS1. [Abstract]2026 Jan 23;302(3):111204. PMID: 41581871
-
BMC CancerEstablishment of a new method for detection of TROP2-positive circulating tumor cells in breast cancer. [Abstract]2025 Nov 21;25(1):1797. PMID: 41272532
-
J VirolEnvelope domain III E324, E351, and E380 mutations lever adaptive evolution of DENV-1 genotype I. [Abstract]2024 Oct 22;98(10):e0118324. PMID: 39230303
-
J Biol Chem2024 Aug;300(8):107499. PMID: 38944125
-
J Biol ChemSplicing factor hnRNPA1 regulates alternative splicing of LOXL2 to enhance the production of LOXL2Δ13. [Abstract]2024 Jul;300(7):107414. PMID: 38810697
-
J Biol ChemUSP36 inhibits apoptosis by deubiquitinating cIAP1 and survivin in colorectal cancer cells. [Abstract]2024 Jul;300(7):107463. PMID: 38876304
-
J VirolRecent H9N2 avian influenza virus lost hemagglutination activity due to a K141N substitution in hemagglutinin. [Abstract]2024 Apr 16;98(4):e0024824. PMID: 38466094
-
J Biol Chem2024 Mar;300(3):105721. PMID: 38311175
-
BMC Cancer2024 Mar 19;24(1):354. PMID: 38504172
-
J Biol ChemTBK1-stabilized ZNF268a recruits SETD4 to methylate TBK1 for efficient interferon signaling. [Abstract]2023 Dec;299(12):105428. PMID: 37926288
-
J Biol Chem2023 Nov;299(11):105351. PMID: 37838174
-
Microbiol Spectr2022 Aug 31;10(4):e0091722. PMID: 35867410
-
Microbiol Spectr2022 Apr 27;10(2):e0227621. PMID: 35404086
-
J VirolARF1 with Sec7 Domain-Dependent GBF1 Activates Coatomer Protein I To Support Classical Swine Fever Virus Entry. [Abstract]2022 Mar 23;96(6):e0219321. PMID: 35044210
-
J VirolCyclophilin A Inhibits Human Respiratory Syncytial Virus (RSV) Replication by Binding to RSV-N through Its PPIase Activity. [Abstract]2021 Jul 12;95(15):e0056321. PMID: 34011546
-
J Biol ChemThe adaptor protein GIPC1 stabilizes the scavenger receptor SR-B1 and increases its cholesterol uptake. [Abstract]2021 Jan-Jun:296:100616. PMID: 33811857
-
J Biol Chem2020 Nov 27;295(48):16393-16410. PMID: 32967966
-
J Biol ChemPerturbation of phosphoglycerate kinase 1 (PGK1) only marginally affects glycolysis in cancer cells. [Abstract]2020 May 8;295(19):6425-6446. PMID: 32217690
-
J Biol Chem2018 Nov 23;293(47):18328-18336. PMID: 30305392
-
J Chromatogr A2026 Feb 8:1768:466675. PMID: 41512648
-
J Cell Physiol2025 Nov;240(11):e70113. PMID: 41287970
-
DevelopmentH3K36me3 modification by SETD2 is essential for Col11a2 and Sema3e transcription to maintain dentinogenesis in mice. [Abstract]2025 Jul 15;152(14):dev204352. PMID: 40554768
-
J Cell Commun SignalMoscatilin alleviates oxidative stress and inflammatory response of Müller cells in diabetic retinopathy through suppressing the p38 mitogen-activated protein kinase/c-Jun N-terminal kinase and nuclear factor kappa-B signaling pathways. [Abstract]2025 Feb 19;19(1):e12059. PMID: 39975983
-
J ImmunolDephosphorylation of T517 on Hemocyanin Is Required for Antibacterial Activity in Penaeus vannamei. [Abstract]2023 May 1;210(9):1396-1407. PMID: 36971684
-
J Biotechnol2023 Mar 20:366:54-64. PMID: 36822476
-
J ImmunolDeacetylation of K481 and K484 on Penaeid Shrimp Hemocyanin Is Critical for Antibacterial Activity. [Abstract]2022 Aug 1;209(3):476-487. PMID: 35851542
-
DevelopmentLoss of perinuclear theca ACTRT1 causes acrosome detachment and severe male subfertility in mice. [Abstract]2022 Jun 15;149(12):dev200489. PMID: 35616329
-
J ImmunolThe IL-33/ST2 Axis Promotes Primary Sjögren's Syndrome by Enhancing Salivary Epithelial Cell Activation and Type 1 Immune Response. [Abstract]2022 Jun 15;208(12):2652-2662. PMID: 35649629
-
J Cell PhysiolVimentin affects colorectal cancer proliferation, invasion, and migration via regulated by activator protein 1. [Abstract]2021 Nov;236(11):7591-7604. PMID: 34041752
-
Regen Ther2020 Oct 16:15:202-209. PMID: 33426220
-
J ImmunolFGFR2 Promotes Expression of PD-L1 in Colorectal Cancer via the JAK/STAT3 Signaling Pathway. [Abstract]2019 May 15;202(10):3065-3075. PMID: 30979816
-
J Hepatocell CarcinomaSilencing NEDD4L Effectively Inhibits the Malignant Behaviors of Hepatocellular Carcinoma. [Abstract]2025 Jul 10:12:1369-1391. PMID: 40661237
-
Vet ResEZH2 enhances PCV2 replication through inhibition of MMP1 and MMP12 transcription activity. [Abstract]2026 Jun 8;57(1):101. PMID: 42260657
-
J Proteome ResProteomics Combined with N-Glycoproteomics to Explore the Pathogenesis of Nasopharyngeal Carcinoma. [Abstract]2025 Dec 5;24(12):6272-6284. PMID: 41269767
-
Ren FailHesperetin attenuates ischemia/reperfusion-induced acute kidney injury by regulating ferroptosis in mice. [Abstract]2025 Dec;47(1):2523573. PMID: 40583332
-
Carcinogenesis2025 Oct 25:bgaf073. PMID: 41139207
-
CarcinogenesisNUF2 and NEK2 promote malignant progression of gallbladder cancer by remodeling the extracellular matrix. [Abstract]2025 Apr 3;46(2):bgaf019. PMID: 40220284
-
J Biomed Mater Res AElastic modulus of hydrogel regulates osteogenic differentiation via liquid-liquid phase separation of YAP. [Abstract]2023 Nov;111(11):1781-1797. PMID: 37494632
-
J Proteome ResProteomic Characterization of Peritoneal Extracellular Vesicles in a Mouse Model of Peritoneal Fibrosis. [Abstract]2023 Mar 3;22(3):908-918. PMID: 36648763
-
EndocrinologyRhoB Promotes Endometrial Stromal Cells Decidualization Via Semaphorin3A/plexinA4 Signaling in Early Pregnancy. [Abstract]2022 Oct 11;163(11):bqac134. PMID: 36047434
-
Diagnostics (Basel)2021 Dec 16;11(12):2371. PMID: 34943607
-
Endocrinology2021 Nov 1;162(11):bqab167. PMID: 34427636
-
EndocrinologyWnt5a Regulates Junctional Function of Sertoli cells Through PCP-mediated Effects on mTORC1 and mTORC2. [Abstract]2021 Oct 1;162(10):bqab149. PMID: 34338758
-
J Gen VirolRules governing genetic exchanges among viral types from different Enterovirus A clusters. [Abstract]2020 Nov;101(11):1145-1155. PMID: 32762804
-
Mol Immunol2026 Jan:189:235-246. PMID: 41485416
-
J Med Virol2025 Nov;97(11):e70661. PMID: 41181874
-
J Nat ProdIdentification of an m6A Natural Inhibitor, Lobeline, That Reverses Lenvatinib Resistance in Hepatocellular Tumors. [Abstract]2024 Aug 23;87(8):1983-1993. PMID: 39136667
-
Biotechnol JHeterologous expression of cyanobacterial gas vesicle proteins in Saccharomyces cerevisiae. [Abstract]2021 Dec;16(12):e2100059. PMID: 34499423
-
PLoS Negl Trop DisUnraveling the role of host kinase PIM1 in Toxoplasma gondii infection: Implications for therapies. [Abstract]2026 Jan 20;20(1):e0013915. PMID: 41557744
-
ACS Chem BiolTargeted O-GlcNAcylation of CK2α Triggers Its Ubiquitin-Proteasome Degradation and Alters Downstream Phosphorylation. [Abstract]2025 Jul 18;20(7):1646-1659. PMID: 40521680
-
Mol Carcinogm6A modification of VEGFA mRNA by RBM15/YTHDF2/IGF2BP3 contributes to angiogenesis of hepatocellular carcinoma. [Abstract]2024 Nov;63(11):2174-2189. PMID: 39092767
-
Mol CarcinogThe cumulative antitumor effects of regorafenib and radiotherapy in hepatocellular carcinoma. [Abstract]2024 Sep;63(9):1738-1749. PMID: 38837427
-
Cancer Med2023 Sep;12(18):18946-18959. PMID: 37694492
-
Exp Cell ResCamptothecin induced DDX5 degradation increased the camptothecin resistance of osteosarcoma. [Abstract]2020 Sep 15;394(2):112148. PMID: 32585151
-
Hum Exp Toxicol2020 Jul;39(7):938-947. PMID: 32081049
-
Exp Cell Res2020 Apr 1;389(1):111847. PMID: 31972218
-
Carbohydr ResIdentification of O-GalNAc-modified proteins interacting with GALNT3 using proximity labeling method. [Abstract]2025 Sep 20:558:109675. PMID: 40992072
-
Brain SciA Four-Week High-Fat Diet Induces Anxiolytic-like Behaviors through Mature BDNF in the mPFC of Mice. [Abstract]2024 Apr 17;14(4):389. PMID: 38672038
-
NeuroscienceProtein Kinase B/Akt1 Phosphorylates Dysbindin-1A at Serine 10 to Regulate Neuronal Development. [Abstract]2022 May 10:490:66-78. PMID: 35124166
-
Biol ReprodSHP2 regulates the HIF-1 signaling pathway in the decidual human endometrial stromal cells. [Abstract]2025 Apr 13;112(4):743-753. PMID: 39893623
-
Biol ReprodDevelopmental proteome dynamics in granulosa and thecal layers from growing follicles to pre-ovulatory duck follicles. [Abstract]2025 Apr 13;112(4):675-691. PMID: 39905481
-
Biol ReprodA novel mechanism regulating pyroptosis-induced fibrosis in endometriosis via lnc-MALAT1/miR-141-3p/NLRP3 pathway. [Abstract]2023 Aug 10;109(2):156-171. PMID: 37233993
-
Mol Biol RepThe investigation of glutamate transporter 1 (GLT-1) degradation pathway in glioblastoma cells. [Abstract]2021 Apr;48(4):3495-3502. PMID: 34003424
-
J Mol Endocrinol2025 Oct 27:JME-25-0033. PMID: 41143604
-
Genes (Basel)2023 Mar 19;14(3):749. PMID: 36981020
-
Genes (Basel)miR-185-5p Regulates Inflammation and Phagocytosis through CDC42/JNK Pathway in Macrophages. [Abstract]2022 Mar 7;13(3):468. PMID: 35328023
-
FEBS LettHuman SND2 mediates ER targeting of GPI-anchored proteins with low hydrophobic GPI attachment signals. [Abstract]2021 Jun;595(11):1542-1558. PMID: 33838053
-
Am J Cancer ResLoss of BRMS2 induces cell growth inhibition and translation capacity reduction in colorectal cancer cells. [Abstract]2021 Mar 1;11(3):930-944. PMID: 33791164
-
Fish Physiol Biochem2025 Jul 30;51(4):129. PMID: 40736925
-
InsectsMolecular Characterizations and Functional Analyses of LmR2D2 in the Locusta migratoria siRNA Pathway. [Abstract]2021 Sep 10;12(9):812. PMID: 34564252
-
Acta HistochemYAP promotes wound healing in diabetic mice by improving endothelial cell function via the regulation of SEMA3B. [Abstract]2026 Apr 27;128(3):152335. PMID: 42048860
-
PeerJOPA1 supports mitochondrial dynamics and immune evasion to CD8+ T cell in lung adenocarcinoma. [Abstract]2022 Dec 21:10:e14543. PMID: 36573240
-
Fitoterapia2018 Jun:127:279-285. PMID: 29540311
-
Discov OncolD-mannose suppresses HIF-1α mediated metabolic reprogramming in clear cell renal cell carcinoma. [Abstract]2025 Oct 21;16(1):1934. PMID: 41118022
-
Tissue Eng Part AThe UCMSC-bFGF/Scaffold System Accelerates the Healing of the Uterine Full-Thickness Injury. [Abstract]2023 Feb;29(3-4):112-125. PMID: 36305369
-
PLoS OneAGR2 expression as a predictive biomarker for therapy response in esophageal squamous cell carcinoma. [Abstract]2022 Nov 3;17(11):e0276990. PMID: 36327302
-
ChembiochemThe Potential Application of Branch-PCR Assembled PTEN Gene Nanovector in Lung Cancer Gene Therapy. [Abstract]2022 Nov 4;23(21):e202200387. PMID: 36073901
-
GeneLactate dehydrogenase a-like 6B is not essential for spermatogenesis and male fertility in mice. [Abstract]2025 Feb 5:936:149100. PMID: 39549775
-
CartilagePKC-δ Promotes IL-1β-Induced Apoptosis of Rat Chondrocytes and Via Activating JNK and P38 MAPK Pathways. [Abstract]2024 Sep;15(3):315-327. PMID: 37491820
-
DNA Cell Biol2021 Sep;40(9):1177-1184. PMID: 34432529
-
Biochem Biophys Res Commun2026 Jul 30:824:153975. PMID: 42166810
-
J Clin Lab AnalGinsenoside Rb1 Targets the HRD1-STING Axis to Mitigate Cholesterol-Induced VSMC Senescence. [Abstract]2026 Mar;40(5):e70172. PMID: 41626813
-
Biochem Biophys Res Commun2025 May 26:760:151673. PMID: 40157288
-
Biochem Biophys Res Commun2023 Apr 23:653:133-139. PMID: 36868077
-
Biochem Biophys Res Commun2020 Sep 10;530(1):160-166. PMID: 32828280
-
Biochem Biophys Res CommunAutophagy inhibition by reversine and its suppressive effects on human hepatocellular carcinoma cells. [Abstract]2020 Jul 12;528(1):105-111. PMID: 32456791
-
Biochem Biophys Res Commun2019 Aug 13;516(1):8-14. PMID: 31182282
-
J BiochemA lipid scramblase TMEM41B is involved in the processing and transport of GPI-anchored proteins. [Abstract]2023 Jul 31;174(2):109-123. PMID: 37279648
-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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-
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Storage
-20°C, 2 years
Attention
1. Avoid repetitive freeze-thaw cycles.
2. DMSO solution thaws slowly in low temperature. Recommend to warm up at 25°C.
3. This product is for R&D use only, not for drug, household, or other uses.
4. For your safety and health, please wear a lab coat and disposable gloves to operate.
Components
| Cat. No. | Product Name | Package |
|---|---|---|
| HY-K0010-1 mL | Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO) | 1 mL |
| HY-K0010-10 mL | Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO) | 1 mL × 10 |
| HY-K0010-50 mL | Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO) | 1 mL × 50 |
| HY-K0010-100 mL | Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO) | 1 mL × 100 |