RAB3A-mediated BAG6 translocation promotes non-small cell lung cancer tumorigenesis and progression

  • Cell Oncol (Dordr). 2025 Oct 22. doi: 10.1007/s13402-025-01123-z.
Xiaoli Liu  #  1  2 ,  Wen Wang  #  1 ,  Wanwei Cao  #  3 ,  Zhanyu Li  #  3 ,  Hao Huang  3 ,  Fang Liu  4 ,  Yang Wang  4 ,  Zhijuan Zhong  4 ,  Hongyu Zhang  5 ,  Xiaofeng Pei  6 ,  Hongtao Chen  7  8
Affiliations
  • 1. Department of Oncology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China.
  • 2. Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China.
  • 3. Department of Pathology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China.
  • 4. Department of Laboratory, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China.
  • 5. Department of Oncology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China. [email protected].
  • 6. Department of Oncology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China. [email protected].
  • 7. Department of Laboratory, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China. [email protected].
  • 8. Department of Laboratory, Xinjiang Medical University Affiliated Second Hospital, Wulumuqi, 830028, China. [email protected].
  • # Contributed equally.
PMID: 41123819 DOI: 10.1007/s13402-025-01123-z
Keywords
BAG6; Cisplatin; Mitophagy; Non-small cell lung cancer; RAB3A; p53/Rb signaling.
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