1. Screening Libraries
  2. Stem Cell Signaling Compound Library

Stem Cell Signaling Compound Library

Cat. No.: HY-L017
Library Contents: XLSX PDF SDF

Adult stem cells are important for tissue homeostasis and regeneration due to their ability to self-renew and generate multiple types of differentiated daughters. Self-renewal is reflected by their capacity to undergo multiple/limitless divisions. Several signaling pathways are involved in self-renewal of stem cells, that is, Notch, Wnt, and Hedgehog pathways or Polycomb family proteins. Recent studies mainly focus on cancer stem cell (CSCs), induced pluripotent stem cell (iPSCs), neural stem cell and maintenance of embryonic stem cell pluripotency. Among them, CSCs have been believed to be responsible for tumor initiation, growth, and recurrence that have implications for cancer therapy.

MCE owns a unique collection of 386 compounds that can be used for stem cell regulatory and signaling pathway research.

MCE Stem Cell Signaling Compound Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 378 compounds supplied in 10 mM solution, 7 compounds supplied in 2 mM solution and 1 compounds supplied in 3 mg/mL solution.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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50 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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2 × 100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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  • Description

  • Product Details

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Description
& Advantages

•   A unique collection of 386 small molecule inhibitors with biological activity used for stem cell regulatory and signaling pathway research.

•   Targets such as GSK-3, Hedgehog, Notch, JAK, ROCK, Wnt, γ-secretase, Casein Kinase, etc.

•   A powerful tool for researching the mechanism behind stem cells, regenerative therapy, drug screening based on tumor stem cells, as well as other pharmaceutical and biological applications.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some protein kinase inhibitors have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   Rich documentation with structure, IC50, and customer reviews.

•   NMR and HPLC validated to ensure the highest purity.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 386 stem cell signaling related compounds supplied as pre-dissolved Solutions or Solid
Solution: 378 compounds supplied in 10 mM solution, 7 compounds supplied in 2 mM solution, 1 compounds supplied in 3 mg/mL solution.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

Stem Cell Signaling Compound Library

Source: MedChem Express

Documentation

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    Product Name:
    Stem Cell Signaling Compound Library
    Cat. No.:
    HY-L017
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack