2. Isotope-Labeled Compounds
  3. Internal Standard for Pesticides & Veterinary Medicine

Internal Standard for Pesticides & Veterinary Medicine

Agricultural products containing pesticide and veterinary drug residues do not mean that they are absolutely unsafe, but whether they will affect human health depends on whether the residue exceeds the standard. Only when the residue exceeds the national testing standards will it have a negative impact on the health of human. For the quantitative detection of residues, isotope-labeled internal standards play their unique advantages. MedChemExpress (MCE) provides a wide variety of isotope-labeled compounds for pesticide and veterinary drug residues to meet different scientific research needs[1].

 

References:

[1] J Hazard Mater. 2022 May 15;430:128413.

Internal Standard for Pesticides & Veterinary Medicine (756):

Cat. No. 상품명 CAS No. Purity 화학구조
  • HY-18569S
    3-Indoleacetic acid-d5 76937-78-5 99.76%
    3-Indoleacetic acid-d5 is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid-d5 can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates.
    3-Indoleacetic acid-d<sub>5</sub>
  • HY-N1428S1
    Citric acid-13C6 287389-42-8 99.90%
    Citric acid-13C6 is the 13C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries.
    Citric acid-<sup>13</sup>C<sub>6</sub>
  • HY-13678S
    Meropenem-d6 1217976-95-8 98.31%
    Meropenem-d6 is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL).
    Meropenem-d<sub>6</sub>
  • HY-14608S3
    L-Glutamic acid-13C5,15N 202468-31-3 99.9%
    L-Glutamic acid-13C5,15N is the 13C- and 15N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
    L-Glutamic acid-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N
  • HY-B0413S
    Fenbendazole-d3 1228182-47-5 99.70%
    Fenbendazole-d3 is a deuterium labeled Fenbendazole. Fenbendazole-d3 is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53.
    Fenbendazole-d<sub>3</sub>
  • HY-117660S1
    Lincomycin-13C,d3
    Lincomycin-13C,d3 (U-10149-13C,d3) is the deuterium and 13C-labeled Lincomycin (HY-117660). Lincomycin (U-10149) is an orally active lincosamide antibiotic. Lincomycin binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice.
    Lincomycin-<sup>13</sup>C,d<sub>3</sub>
  • HY-B1218S
    Sulfaphenazole-d4 2702538-04-1 99.66%
    Sulfaphenazole-d4 is the deuterium labeled Sulfaphenazole (HY-B1218). Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion.
    Sulfaphenazole-d<sub>4</sub>
  • HY-B0469S1
    Medroxyprogesterone acetate-d7
    Medroxyprogesterone acetate-d7 (Medroxyprogesterone 17-acetate-d7) is the deuterium labeled Medroxyprogesterone acetate (HY-B0469) . Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors.
    Medroxyprogesterone acetate-d<sub>7</sub>
  • HY-B1337S1
    Choline-d9 chloride 61037-86-3 99.9%
    Choline-d9 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
    Choline-d<sub>9</sub> chloride
  • HY-Y0271S2
    Urea-13C,15N2 58069-83-3 99.95%
    Urea-13C,15N2 is the 13C and 15N labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
    Urea-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-B0167S
    Salicylic acid-d6 285979-87-5 99.82%
    Salicylic acid-d6 is a deuterium labeled Salicylic acid (HY-B0167). Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation.
    Salicylic acid-d<sub>6</sub>
  • HY-66005S
    Acetaminophen-d4 64315-36-2 99.60%
    Acetaminophen-d4 is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
    Acetaminophen-d<sub>4</sub>
  • HY-B0141S1
    Estradiol-d4 66789-03-5 99.55%
    Estradiol-d4 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
    Estradiol-d<sub>4</sub>
  • HY-N1428S
    Citric acid-d4 147664-83-3 99.31%
    Citric acid-d4 is the deuterium labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries.
    Citric acid-d<sub>4</sub>
  • HY-B1337S
    Choline-d4 chloride 285979-70-6 99.90%
    Choline-d4 (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
    Choline-d<sub>4</sub> chloride
  • HY-18569S3
    3-Indoleacetic acid-d7 1173020-21-7 99.84%
    3-Indoleacetic acid-d7 is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.
    3-Indoleacetic acid-d<sub>7</sub>
  • HY-B0141S2
    Estradiol-d5 221093-45-4 99.73%
    Estradiol-d5 is deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
    Estradiol-d<sub>5</sub>
  • HY-W001132S4
    Indole-d7 73509-20-3 99.94%
    Indole-d7 is the deuterium labeled Indole. Indole is an endogenous metabolite.
    Indole-d<sub>7</sub>
  • HY-B1618S
    Corticosterone-d8 1271728-07-4 99.91%
    Corticosterone-d8 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
    Corticosterone-d<sub>8</sub>
  • HY-B0322S
    Sulfamethoxazole-d4 1020719-86-1 99.32%
    Sulfamethoxazole-d4 (Ro 4-2130-d4) is a deuterium labeled Sulfamethoxazole (HY-B0322). Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis.
    Sulfamethoxazole-d<sub>4</sub>