1. Isotope-Labeled Compounds
  2. Internal Standard for Pesticides & Veterinary Medicine

Internal Standard for Pesticides & Veterinary Medicine

Agricultural products containing pesticide and veterinary drug residues do not mean that they are absolutely unsafe, but whether they will affect human health depends on whether the residue exceeds the standard. Only when the residue exceeds the national testing standards will it have a negative impact on the health of human. For the quantitative detection of residues, isotope-labeled internal standards play their unique advantages. MedChemExpress (MCE) provides a wide variety of isotope-labeled compounds for pesticide and veterinary drug residues to meet different scientific research needs[1].

 

References:

[1] J Hazard Mater. 2022 May 15;430:128413.

Internal Standard for Pesticides & Veterinary Medicine (566):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B0141S1
    Estradiol-d4 66789-03-5 99.55%
    Estradiol-d4 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].
    Estradiol-d<sub>4</sub>
  • HY-18569S
    3-Indoleacetic acid-d5 76937-78-5 99.84%
    3-Indoleacetic acid-d5 is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d5 can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].
    3-Indoleacetic acid-d<sub>5</sub>
  • HY-B0413S
    Fenbendazole-d3 1228182-47-5 99.46%
    Fenbendazole-d3 is a deuterium labeled Fenbendazole. Fenbendazole-d3 is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53[1][2][3][4].
    Fenbendazole-d<sub>3</sub>
  • HY-66005S
    Acetaminophen-d4 64315-36-2 99.60%
    Acetaminophen-d4 is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].
    Acetaminophen-d<sub>4</sub>
  • HY-B0322S
    Sulfamethoxazole-d4 1020719-86-1 99.56%
    Sulfamethoxazole-d4 is a deuterium labeled Sulfamethoxazole (Ro 4-2130). Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic[1].
    Sulfamethoxazole-d<sub>4</sub>
  • HY-B0343AS
    Sarafloxacin-d8 hydrochloride 2733145-07-6
    Sarafloxacin-d8 (A-56620-d8) hydrochloride is the deuterium labeled Sarafloxacin hydrochloride. Sarafloxacin hydrochloride (A-56620 hydrochloride) is a quinolone antibiotic drug.
    Sarafloxacin-d<sub>8</sub> hydrochloride
  • HY-W067028S
    Semicarbazide-13C,15N2 hydrochloride 1173020-16-0
    Semicarbazide-13C,15N2 hydrochloride is 15N and 13C labeled Semicarbazide.
    Semicarbazide-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub> hydrochloride
  • HY-B0175S
    Toltrazuril-d3 1353867-75-0
    Toltrazuril-d3 is deuterated labeled Toltrazuril. Toltrazuril (BAY-i 9142) is an antiprotozoal agent that acts upon Coccidia parasites.
    Toltrazuril-d<sub>3</sub>
  • HY-B1618S
    Corticosterone-d8 1271728-07-4 99.22%
    Corticosterone-d8 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
    Corticosterone-d<sub>8</sub>
  • HY-13678S
    Meropenem-d6 1217976-95-8 ≥98.0%
    Meropenem-d6 is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1][2].
    Meropenem-d<sub>6</sub>
  • HY-B0125S
    Ofloxacin-d3 1173147-91-5 99.77%
    Ofloxacin-d3 is the deuterium labeled Ofloxacin[1].
    Ofloxacin-d<sub>3</sub>
  • HY-Y0271S2
    Urea-13C,15N2 58069-83-3 99.10%
    Urea-13C,15N2 is the 13C and 15N labeled Urea[1]. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
    Urea-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-17506S
    Azithromycin-d3 163921-65-1
    Azithromycin-d3 is the deuterium labeled Azithromycin. Azithromycin (CP-62993) is a macrolide antibiotic useful for the treatment of a number of bacterial infections[1][2].
    Azithromycin-d<sub>3</sub>
  • HY-B1618S1
    Corticosterone-d4 2243253-91-8 99.17%
    Corticosterone-d4 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
    Corticosterone-d<sub>4</sub>
  • HY-B0141S
    Estradiol-d3 79037-37-9 98.60%
    Estradiol-d3 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
    Estradiol-d<sub>3</sub>
  • HY-10582S1
    Flurbiprofen-d5 215175-76-1 ≥99.0%
    Flurbiprofen-d5 is the deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer[1][2][3].
    Flurbiprofen-d<sub>5</sub>
  • HY-B0502S
    Enrofloxacin-d5 1173021-92-5 ≥98.0%
    Enrofloxacin-d5 is the deuterium labeled Enrofloxacin. Enrofloxacin (BAY Vp 2674) is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis.
    Enrofloxacin-d<sub>5</sub>
  • HY-B0167S
    Salicylic acid-d6 285979-87-5 99.83%
    Salicylic acid-d6 is a deuterium labeled Salicylic acid. Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation[1].
    Salicylic acid-d<sub>6</sub>
  • HY-B0151S2
    Pregnenolone-d4-1 61574-54-7 99%
    Pregnenolone-d4-1 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].
    Pregnenolone-d<sub>4</sub>-1
  • HY-103638S
    3-Methoxytyramine-d4 hydrochloride 1216788-76-9 ≥99.0%
    3-Methoxytyramine-d4 (hydrochloride) is the deuterium labeled 3-Methoxytyramine hydrochloride. 3-Methoxytyramine hydrochloride is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1)[1][2].
    3-Methoxytyramine-d<sub>4</sub> hydrochloride